{"id":"https://openalex.org/W2080434471","doi":"https://doi.org/10.1016/j.vaccine.2012.06.007","title":"Vaccination with Clostridium perfringens recombinant proteins in combination with Montanide\u2122 ISA 71 VG adjuvant increases protection against experimental necrotic enteritis in commercial broiler chickens","display_name":"Vaccination with Clostridium perfringens recombinant proteins in combination with Montanide\u2122 ISA 71 VG adjuvant increases protection against experimental necrotic enteritis in commercial broiler chickens","publication_year":2012,"publication_date":"2012-06-18","ids":{"openalex":"https://openalex.org/W2080434471","doi":"https://doi.org/10.1016/j.vaccine.2012.06.007","mag":"2080434471","pmid":"https://pubmed.ncbi.nlm.nih.gov/22713719"},"language":"en","primary_location":{"id":"doi:10.1016/j.vaccine.2012.06.007","doi":"https://doi.org/10.1016/j.vaccine.2012.06.007","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2012.06.007","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111813207","display_name":"Seung I. Jang","orcid":"https://orcid.org/0000-0003-2522-4310","observed_orcids":["https://orcid.org/0000-0003-2522-4310"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seung I. Jang","raw_affiliation_strings":["Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service-US Department of Agriculture, Beltsville, MD 20705, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service-US Department of Agriculture, Beltsville, MD 20705, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035053381","display_name":"Hyun Soon Lillehoj","orcid":"https://orcid.org/0000-0001-7755-6216","observed_orcids":["https://orcid.org/0000-0001-7755-6216"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hyun S. Lillehoj","raw_affiliation_strings":["Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020772215","display_name":"Sung Hyen Lee","orcid":"https://orcid.org/0000-0002-7886-4752","observed_orcids":["https://orcid.org/0000-0002-7886-4752"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sung-Hyen Lee","raw_affiliation_strings":["Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018052057","display_name":"Kyung-Woo Lee","orcid":"https://orcid.org/0000-0002-3533-7979","observed_orcids":["https://orcid.org/0000-0002-3533-7979"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyung Woo Lee","raw_affiliation_strings":["Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, MD 20705, USA","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041148840","display_name":"Erik Peter Lillehoj","orcid":"https://orcid.org/0000-0002-2710-1704","observed_orcids":["https://orcid.org/0000-0002-2710-1704"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erik P. Lillehoj","raw_affiliation_strings":["Department of Pediatrics, University of Maryland, School of Medicine, Baltimore, MD 21201, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Maryland, School of Medicine, Baltimore, MD 21201, USA","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055934572","display_name":"Yeong Ho Hong","orcid":"https://orcid.org/0000-0002-4510-7851","observed_orcids":["https://orcid.org/0000-0002-4510-7851"]},"institutions":[{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yeong Ho Hong","raw_affiliation_strings":["Department of Animal Science and Technology, Chung-Ang University, Anseong 456-756, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science and Technology, Chung-Ang University, Anseong 456-756, South Korea","institution_ids":["https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010025414","display_name":"Dong-Jun An","orcid":"https://orcid.org/0000-0002-5690-4039","observed_orcids":["https://orcid.org/0000-0002-5690-4039"]},"institutions":[{"id":"https://openalex.org/I4210160954","display_name":"Animal and Plant Quarantine Agency","ror":"https://ror.org/04sbe6g90","country_code":"KR","type":"government","lineage":["https://openalex.org/I4210160954"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dong-Jun An","raw_affiliation_strings":["Animal Plant and Fisheries Quarantine and Inspection Agency, Ministry for Food, Agriculture, Forestry and Fisheries, Anyang, Kyunggido 430-824, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Plant and Fisheries Quarantine and Inspection Agency, Ministry for Food, Agriculture, Forestry and Fisheries, Anyang, Kyunggido 430-824, South Korea","institution_ids":["https://openalex.org/I4210160954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085689759","display_name":"Wooseog Jeong","orcid":"https://orcid.org/0000-0002-3214-9323","observed_orcids":["https://orcid.org/0000-0002-3214-9323"]},"institutions":[{"id":"https://openalex.org/I4210160954","display_name":"Animal and Plant Quarantine Agency","ror":"https://ror.org/04sbe6g90","country_code":"KR","type":"government","lineage":["https://openalex.org/I4210160954"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Wooseog Jeong","raw_affiliation_strings":["Animal Plant and Fisheries Quarantine and Inspection Agency, Ministry for Food, Agriculture, Forestry and Fisheries, Anyang, Kyunggido 430-824, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Plant and Fisheries Quarantine and Inspection Agency, Ministry for Food, Agriculture, Forestry and Fisheries, Anyang, Kyunggido 430-824, South Korea","institution_ids":["https://openalex.org/I4210160954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010232095","display_name":"Ji-Eun Chun","orcid":"https://orcid.org/0000-0003-3844-8567","observed_orcids":["https://orcid.org/0000-0003-3844-8567"]},"institutions":[{"id":"https://openalex.org/I4210160954","display_name":"Animal and Plant Quarantine Agency","ror":"https://ror.org/04sbe6g90","country_code":"KR","type":"government","lineage":["https://openalex.org/I4210160954"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji-Eun Chun","raw_affiliation_strings":["Animal Plant and Fisheries Quarantine and Inspection Agency, Ministry for Food, Agriculture, Forestry and Fisheries, Anyang, Kyunggido 430-824, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Animal Plant and Fisheries Quarantine and Inspection Agency, Ministry for Food, Agriculture, Forestry and Fisheries, Anyang, Kyunggido 430-824, South Korea","institution_ids":["https://openalex.org/I4210160954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103480443","display_name":"Fran\u00e7ois Bertrand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267296","display_name":"SEPPIC (France)","ror":"https://ror.org/022s7wx37","country_code":"FR","type":"company","lineage":["https://openalex.org/I4405267296"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fran\u00e7ois Bertrand","raw_affiliation_strings":["SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France","institution_ids":["https://openalex.org/I4405267296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063648180","display_name":"Laurent Dupuis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267296","display_name":"SEPPIC (France)","ror":"https://ror.org/022s7wx37","country_code":"FR","type":"company","lineage":["https://openalex.org/I4405267296"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laurent Dupuis","raw_affiliation_strings":["SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France","institution_ids":["https://openalex.org/I4405267296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090689906","display_name":"S. Deville","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267296","display_name":"SEPPIC (France)","ror":"https://ror.org/022s7wx37","country_code":"FR","type":"company","lineage":["https://openalex.org/I4405267296"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S\u00e9bastien Deville","raw_affiliation_strings":["SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France","institution_ids":["https://openalex.org/I4405267296"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057177890","display_name":"Juliette Ben Arous","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267296","display_name":"SEPPIC (France)","ror":"https://ror.org/022s7wx37","country_code":"FR","type":"company","lineage":["https://openalex.org/I4405267296"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Juliette Ben Arous","raw_affiliation_strings":["SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SEPPIC, 22 Terrasse Bellini, 92800 Puteaux, France","institution_ids":["https://openalex.org/I4405267296"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5035053381"],"corresponding_institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":null,"fwci":6.595,"has_fulltext":false,"cited_by_count":93,"citation_normalized_percentile":{"value":0.97378377,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"30","issue":"36","first_page":"5401","last_page":"5406"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12691","display_name":"Coccidia and coccidiosis research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clostridium-perfringens","display_name":"Clostridium perfringens","score":0.968999981880188},{"id":"https://openalex.org/keywords/necrotic-enteritis","display_name":"necrotic enteritis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/recombinant-protein-vaccine","display_name":"recombinant protein vaccine","score":0.8140000104904175},{"id":"https://openalex.org/keywords/adjuvants","display_name":"adjuvants","score":0.8130000233650208},{"id":"https://openalex.org/keywords/netb-toxin","display_name":"NetB toxin","score":0.9739999771118164},{"id":"https://openalex.org/keywords/alpha-toxin","display_name":"alpha-toxin","score":0.9419999718666077},{"id":"https://openalex.org/keywords/elongation-factor-tu","display_name":"elongation factor Tu","score":0.9610000252723694},{"id":"https://openalex.org/keywords/broiler-chickens","display_name":"broiler chickens","score":0.9779999852180481},{"id":"https://openalex.org/keywords/intestinal-lesions","display_name":"intestinal lesions","score":0.6769999861717224},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8379999995231628},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.9629999995231628},{"id":"https://openalex.org/keywords/antibody-response","display_name":"antibody response","score":0.3720000088214874}],"concepts":[{"id":"https://openalex.org/C2779116991","wikidata":"https://www.wikidata.org/wiki/Q309465","display_name":"Clostridium perfringens","level":3,"score":0.7175496816635132},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.6639158129692078},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.606340229511261},{"id":"https://openalex.org/C22889606","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Antibody titer","level":4,"score":0.6018154621124268},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.5759069323539734},{"id":"https://openalex.org/C2777367657","wikidata":"https://www.wikidata.org/wiki/Q184651","display_name":"Toxin","level":2,"score":0.5720367431640625},{"id":"https://openalex.org/C2778773781","wikidata":"https://www.wikidata.org/wiki/Q3497618","display_name":"Eimeria maxima","level":3,"score":0.4613198935985565},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.46017566323280334},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4554639756679535},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.4201532006263733},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.39132508635520935},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.28967559337615967},{"id":"https://openalex.org/C2777976947","wikidata":"https://www.wikidata.org/wiki/Q795375","display_name":"Eimeria","level":2,"score":0.0874391496181488},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.055969566106796265},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.04286181926727295},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000276","descriptor_name":"Adjuvants, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001428","descriptor_name":"Bacterial Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001428","descriptor_name":"Bacterial Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D003015","descriptor_name":"Clostridium Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003015","descriptor_name":"Clostridium Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D003015","descriptor_name":"Clostridium Infections","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D003016","descriptor_name":"Clostridium perfringens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004751","descriptor_name":"Enteritis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004751","descriptor_name":"Enteritis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D004751","descriptor_name":"Enteritis","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D008353","descriptor_name":"Mannitol","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D009829","descriptor_name":"Oleic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011201","descriptor_name":"Poultry Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011201","descriptor_name":"Poultry Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011201","descriptor_name":"Poultry Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018925","descriptor_name":"Chemokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.vaccine.2012.06.007","doi":"https://doi.org/10.1016/j.vaccine.2012.06.007","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2012.06.007","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},{"id":"pmid:22713719","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22713719","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.8409000039100647,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1449114343","https://openalex.org/W1563659068","https://openalex.org/W1964610623","https://openalex.org/W1969256725","https://openalex.org/W1987420509","https://openalex.org/W1990619325","https://openalex.org/W1992948287","https://openalex.org/W1994371693","https://openalex.org/W1999225385","https://openalex.org/W2001474512","https://openalex.org/W2012749673","https://openalex.org/W2034038126","https://openalex.org/W2034965138","https://openalex.org/W2037519719","https://openalex.org/W2041528883","https://openalex.org/W2077385052","https://openalex.org/W2077844467","https://openalex.org/W2087560843","https://openalex.org/W2091722523","https://openalex.org/W2098167705","https://openalex.org/W2100706861","https://openalex.org/W2117608098","https://openalex.org/W2141178521","https://openalex.org/W2141998772","https://openalex.org/W2333146760"],"related_works":["https://openalex.org/W2603515229","https://openalex.org/W2098119546","https://openalex.org/W4297995602","https://openalex.org/W4408459882","https://openalex.org/W4283314507","https://openalex.org/W4387958580","https://openalex.org/W2141178521","https://openalex.org/W2003545867","https://openalex.org/W2044396650","https://openalex.org/W2156218941"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}