{"id":"https://openalex.org/W2080431429","doi":"https://doi.org/10.1517/13543776.4.9.1037","title":"Overview: Fusion proteins: Fundamental and therapeutic applications","display_name":"Overview: Fusion proteins: Fundamental and therapeutic applications","publication_year":1994,"publication_date":"1994-09-01","ids":{"openalex":"https://openalex.org/W2080431429","doi":"https://doi.org/10.1517/13543776.4.9.1037","mag":"2080431429"},"language":"en","primary_location":{"id":"doi:10.1517/13543776.4.9.1037","doi":"https://doi.org/10.1517/13543776.4.9.1037","is_oa":false,"landing_page_url":"https://doi.org/10.1517/13543776.4.9.1037","pdf_url":null,"source":{"id":"https://openalex.org/S3784663","display_name":"Expert Opinion on Therapeutic Patents","issn_l":"1354-3776","issn":["1354-3776","1744-7674"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Therapeutic Patents","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048303857","display_name":"Carrie Baker Brachmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carrie Baker Brachmann","raw_affiliation_strings":["Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD, 21205, USA","Johns Hopkins University ("],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD, 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Johns Hopkins University (","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075536007","display_name":"Jef D. Boeke","orcid":"https://orcid.org/0000-0001-5322-4946","observed_orcids":["https://orcid.org/0000-0001-5322-4946"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jef D Boeke","raw_affiliation_strings":["Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD, 21205, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD, 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.11758324,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"4","issue":"9","first_page":"1037","last_page":"1051"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.7192000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.7192000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.11949999630451202,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.05310000106692314,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fusion-protein","display_name":"fusion protein","score":1.0},{"id":"https://openalex.org/keywords/therapeutic-use","display_name":"therapeutic applications","score":0.6389999985694885},{"id":"https://openalex.org/keywords/protein-engineering","display_name":"protein engineering","score":0.5120000243186951},{"id":"https://openalex.org/keywords/recombinant-protein","display_name":"recombinant protein","score":0.6169999837875366},{"id":"https://openalex.org/keywords/drug-development","display_name":"drug development","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5422157049179077},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44154274463653564},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.430698424577713},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3282164931297302},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31548404693603516},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18224167823791504},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.10432595014572144},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1517/13543776.4.9.1037","doi":"https://doi.org/10.1517/13543776.4.9.1037","is_oa":false,"landing_page_url":"https://doi.org/10.1517/13543776.4.9.1037","pdf_url":null,"source":{"id":"https://openalex.org/S3784663","display_name":"Expert Opinion on Therapeutic Patents","issn_l":"1354-3776","issn":["1354-3776","1744-7674"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Therapeutic Patents","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W95253480","https://openalex.org/W1492813788","https://openalex.org/W1523930697","https://openalex.org/W1549507201","https://openalex.org/W1561547954","https://openalex.org/W1567346833","https://openalex.org/W1571941406","https://openalex.org/W1585168522","https://openalex.org/W1656315112","https://openalex.org/W1852101032","https://openalex.org/W1884238430","https://openalex.org/W1964896501","https://openalex.org/W1989053318","https://openalex.org/W1990607884","https://openalex.org/W1992526113","https://openalex.org/W1996223704","https://openalex.org/W1996427305","https://openalex.org/W1998511748","https://openalex.org/W1999149594","https://openalex.org/W2000315664","https://openalex.org/W2001949463","https://openalex.org/W2010649076","https://openalex.org/W2011729980","https://openalex.org/W2016453061","https://openalex.org/W2018414056","https://openalex.org/W2018782505","https://openalex.org/W2020891741","https://openalex.org/W2026723170","https://openalex.org/W2028673291","https://openalex.org/W2029852810","https://openalex.org/W2032806769","https://openalex.org/W2041265532","https://openalex.org/W2045117614","https://openalex.org/W2046110140","https://openalex.org/W2052150715","https://openalex.org/W2055609042","https://openalex.org/W2056216896","https://openalex.org/W2056403651","https://openalex.org/W2057209113","https://openalex.org/W2061073014","https://openalex.org/W2065232854","https://openalex.org/W2071482027","https://openalex.org/W2074969682","https://openalex.org/W2075097399","https://openalex.org/W2079749468","https://openalex.org/W2084429764","https://openalex.org/W2085317906","https://openalex.org/W2088854448","https://openalex.org/W2090286778","https://openalex.org/W2126020222","https://openalex.org/W2146026497","https://openalex.org/W2156037313","https://openalex.org/W2156782507","https://openalex.org/W2170159375","https://openalex.org/W2171023157","https://openalex.org/W2220274965","https://openalex.org/W2315494976"],"related_works":["https://openalex.org/W4239241993","https://openalex.org/W7099127137","https://openalex.org/W7100919936","https://openalex.org/W6981045200","https://openalex.org/W2528484038","https://openalex.org/W4315479718","https://openalex.org/W2595536409","https://openalex.org/W2072277836","https://openalex.org/W4250482253","https://openalex.org/W1933079064"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-08-15T07:11:24.734988","created_date":"2016-06-24T00:00:00"}
