{"id":"https://openalex.org/W2080240125","doi":"https://doi.org/10.1016/j.molcel.2011.07.025","title":"A Primate Herpesvirus Uses the Integrator Complex to Generate Viral MicroRNAs","display_name":"A Primate Herpesvirus Uses the Integrator Complex to Generate Viral MicroRNAs","publication_year":2011,"publication_date":"2011-09-01","ids":{"openalex":"https://openalex.org/W2080240125","doi":"https://doi.org/10.1016/j.molcel.2011.07.025","mag":"2080240125","pmid":"https://pubmed.ncbi.nlm.nih.gov/21925386","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3176678"},"language":"en","primary_location":{"id":"doi:10.1016/j.molcel.2011.07.025","doi":"https://doi.org/10.1016/j.molcel.2011.07.025","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.molcel.2011.07.025","pdf_url":"http://www.cell.com/article/S1097276511005909/pdf","source":{"id":"https://openalex.org/S156208185","display_name":"Molecular Cell","issn_l":"1097-2765","issn":["1097-2765","1097-4164"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S1097276511005909/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016241654","display_name":"Demi\u00e1n Cazalla","orcid":"https://orcid.org/0000-0002-9076-3655","observed_orcids":["https://orcid.org/0000-0002-9076-3655"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Demi\u00e1n Cazalla","raw_affiliation_strings":["Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051515439","display_name":"Mingyi Xie","orcid":"https://orcid.org/0000-0001-7955-197X","observed_orcids":["https://orcid.org/0000-0001-7955-197X"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mingyi Xie","raw_affiliation_strings":["Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA","Howard Hughes Medical Institute, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035064101","display_name":"JOAN ARGETSINGER STEITZ","orcid":"https://orcid.org/0000-0002-0534-8722","observed_orcids":["https://orcid.org/0000-0002-0534-8722"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joan\u00a0A. Steitz","raw_affiliation_strings":["Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA","Howard Hughes Medical Institute, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Boyer Center for Molecular Medicine, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5035064101"],"corresponding_institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I32971472"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":3.8574,"has_fulltext":false,"cited_by_count":118,"citation_normalized_percentile":{"value":0.9363121,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"43","issue":"6","first_page":"982","last_page":"992"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.4494999945163727,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.4494999945163727,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.3118000030517578,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.02459999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpesvirus-saimiri","display_name":"Herpesvirus saimiri","score":0.9350000023841858},{"id":"https://openalex.org/keywords/integrator-complex","display_name":"Integrator complex","score":0.9580000042915344},{"id":"https://openalex.org/keywords/3-end-processing","display_name":"3' end processing","score":0.7699999809265137},{"id":"https://openalex.org/keywords/microprocessor-complex","display_name":"microprocessor complex","score":0.7649999856948853},{"id":"https://openalex.org/keywords/exportin-5","display_name":"XPO5","score":0.9620000123977661},{"id":"https://openalex.org/keywords/dicer","display_name":"Dicer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/argonaute-proteins","display_name":"Argonaute proteins","score":0.6990000009536743},{"id":"https://openalex.org/keywords/cis-regulatory-elements","display_name":"cis-regulatory elements","score":0.7699999809265137},{"id":"https://openalex.org/keywords/gammaherpesviruses","display_name":"gammaherpesvirus","score":0.7440000176429749},{"id":"https://openalex.org/keywords/latent-infection","display_name":"latent infection","score":0.5429999828338623},{"id":"https://openalex.org/keywords/non-coding-rna","display_name":"non-coding RNA","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9594911336898804},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6445268988609314},{"id":"https://openalex.org/C79518650","wikidata":"https://www.wikidata.org/wiki/Q2081431","display_name":"Integrator","level":3,"score":0.527695894241333},{"id":"https://openalex.org/C2780509455","wikidata":"https://www.wikidata.org/wiki/Q7380","display_name":"Primate","level":2,"score":0.5163270831108093},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4625081419944763},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.45355919003486633},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.24437075853347778},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23416370153427124},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07660654187202454},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06367406249046326},{"id":"https://openalex.org/C2776257435","wikidata":"https://www.wikidata.org/wiki/Q1576430","display_name":"Bandwidth (computing)","level":2,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002144","descriptor_name":"Callithrix","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006567","descriptor_name":"Herpesvirus 2, Saimiriine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012367","descriptor_name":"RNA, Viral","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D012367","descriptor_name":"RNA, Viral","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D043244","descriptor_name":"Ribonuclease III","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.molcel.2011.07.025","doi":"https://doi.org/10.1016/j.molcel.2011.07.025","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.molcel.2011.07.025","pdf_url":"http://www.cell.com/article/S1097276511005909/pdf","source":{"id":"https://openalex.org/S156208185","display_name":"Molecular Cell","issn_l":"1097-2765","issn":["1097-2765","1097-4164"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cell","raw_type":"journal-article"},{"id":"pmid:21925386","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21925386","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular cell","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2445439","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3176678","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3176678","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3176678","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Mol Cell","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.molcel.2011.07.025","doi":"https://doi.org/10.1016/j.molcel.2011.07.025","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.molcel.2011.07.025","pdf_url":"http://www.cell.com/article/S1097276511005909/pdf","source":{"id":"https://openalex.org/S156208185","display_name":"Molecular Cell","issn_l":"1097-2765","issn":["1097-2765","1097-4164"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G251346309","display_name":null,"funder_award_id":"CA-16038","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8624074680","display_name":"Molecular Basis of Cancer Virus Replication, Transformation, and Innate Defense","funder_award_id":"P01CA016038","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2080240125.pdf"},"referenced_works_count":76,"referenced_works":["https://openalex.org/W88010964","https://openalex.org/W1514610153","https://openalex.org/W1525850266","https://openalex.org/W1608089360","https://openalex.org/W1793762009","https://openalex.org/W1874987427","https://openalex.org/W1910404793","https://openalex.org/W1912540205","https://openalex.org/W1972628058","https://openalex.org/W1978105099","https://openalex.org/W1983514447","https://openalex.org/W1987109078","https://openalex.org/W1988625317","https://openalex.org/W1989917351","https://openalex.org/W1995399992","https://openalex.org/W2004445056","https://openalex.org/W2005090326","https://openalex.org/W2008945738","https://openalex.org/W2010890469","https://openalex.org/W2011039989","https://openalex.org/W2011058860","https://openalex.org/W2014064723","https://openalex.org/W2015238489","https://openalex.org/W2017426710","https://openalex.org/W2019387053","https://openalex.org/W2020120461","https://openalex.org/W2031176852","https://openalex.org/W2032034734","https://openalex.org/W2034740353","https://openalex.org/W2045402423","https://openalex.org/W2048158327","https://openalex.org/W2054109341","https://openalex.org/W2056573404","https://openalex.org/W2059357290","https://openalex.org/W2059382687","https://openalex.org/W2061664626","https://openalex.org/W2062332984","https://openalex.org/W2064132925","https://openalex.org/W2066213138","https://openalex.org/W2070571588","https://openalex.org/W2072155079","https://openalex.org/W2073718731","https://openalex.org/W2079963781","https://openalex.org/W2086848163","https://openalex.org/W2099517697","https://openalex.org/W2103485233","https://openalex.org/W2106929712","https://openalex.org/W2107961632","https://openalex.org/W2110952184","https://openalex.org/W2112192177","https://openalex.org/W2113327117","https://openalex.org/W2121382548","https://openalex.org/W2123079914","https://openalex.org/W2128882718","https://openalex.org/W2129363188","https://openalex.org/W2130993320","https://openalex.org/W2133074943","https://openalex.org/W2136148915","https://openalex.org/W2136991248","https://openalex.org/W2137257434","https://openalex.org/W2139074713","https://openalex.org/W2140995557","https://openalex.org/W2142798790","https://openalex.org/W2143261855","https://openalex.org/W2147651981","https://openalex.org/W2148189550","https://openalex.org/W2149291473","https://openalex.org/W2149385968","https://openalex.org/W2150351594","https://openalex.org/W2151371371","https://openalex.org/W2155412493","https://openalex.org/W2159204828","https://openalex.org/W2168230240","https://openalex.org/W2169401299","https://openalex.org/W3040523477","https://openalex.org/W4214489112"],"related_works":["https://openalex.org/W2254385280","https://openalex.org/W2153749165","https://openalex.org/W2139925467","https://openalex.org/W1514610153","https://openalex.org/W2148189550","https://openalex.org/W2031176852","https://openalex.org/W2762436345","https://openalex.org/W3198170853","https://openalex.org/W2079963781","https://openalex.org/W1995399992"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":18},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
