{"id":"https://openalex.org/W2080201744","doi":"https://doi.org/10.1248/bpb.19.308","title":"Comparative Fungicidal Activity of a New Quaternary Ammonium Salt, N-Alkyl-N-2-hydroxyethyl-N,N-dimethylammonium Butyl Phosphate and Commonly Used Disinfectants.","display_name":"Comparative Fungicidal Activity of a New Quaternary Ammonium Salt, N-Alkyl-N-2-hydroxyethyl-N,N-dimethylammonium Butyl Phosphate and Commonly Used Disinfectants.","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W2080201744","doi":"https://doi.org/10.1248/bpb.19.308","mag":"2080201744","pmid":"https://pubmed.ncbi.nlm.nih.gov/8850330"},"language":"en","primary_location":{"id":"doi:10.1248/bpb.19.308","doi":"https://doi.org/10.1248/bpb.19.308","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.19.308","pdf_url":"https://www.jstage.jst.go.jp/article/bpb1993/19/2/19_2_308/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/bpb1993/19/2/19_2_308/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Shin OHTA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129652","display_name":"Shinshu University Hospital","ror":"https://ror.org/03a2hf118","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shin OHTA","raw_affiliation_strings":["Department of Pharmacy, Shinshu University Hospital, Nagano, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Shinshu University Hospital, Nagano, Japan","institution_ids":["https://openalex.org/I4210129652"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Masahiro MAKINO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129652","display_name":"Shinshu University Hospital","ror":"https://ror.org/03a2hf118","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129652"]},{"id":"https://openalex.org/I4405265156","display_name":"Nicca Chemical Co., Ltd. (Japan)","ror":"https://ror.org/04140zw73","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405265156"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro MAKINO","raw_affiliation_strings":["/ Department of Research and Development, Nicca Chemical Co., Ltd., / Department of Pharmacy, Shinshu University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"/ Department of Research and Development, Nicca Chemical Co., Ltd., / Department of Pharmacy, Shinshu University Hospital","institution_ids":["https://openalex.org/I4210129652","https://openalex.org/I4405265156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050510524","display_name":"Katsuhiro Nagai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129652","display_name":"Shinshu University Hospital","ror":"https://ror.org/03a2hf118","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129652"]},{"id":"https://openalex.org/I4405265156","display_name":"Nicca Chemical Co., Ltd. (Japan)","ror":"https://ror.org/04140zw73","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405265156"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuhiro NAGAI","raw_affiliation_strings":["/ Department of Research and Development, Nicca Chemical Co., Ltd., / Department of Pharmacy, Shinshu University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"/ Department of Research and Development, Nicca Chemical Co., Ltd., / Department of Pharmacy, Shinshu University Hospital","institution_ids":["https://openalex.org/I4210129652","https://openalex.org/I4405265156"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110329899","display_name":"HIROSHI ZENDA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210129652","display_name":"Shinshu University Hospital","ror":"https://ror.org/03a2hf118","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210129652"]},{"id":"https://openalex.org/I4405265156","display_name":"Nicca Chemical Co., Ltd. (Japan)","ror":"https://ror.org/04140zw73","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405265156"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi ZENDA","raw_affiliation_strings":["/ Department of Research and Development, Nicca Chemical Co., Ltd., / Department of Pharmacy, Shinshu University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"/ Department of Research and Development, Nicca Chemical Co., Ltd., / Department of Pharmacy, Shinshu University Hospital","institution_ids":["https://openalex.org/I4210129652","https://openalex.org/I4405265156"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2988,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.5435967,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"19","issue":"2","first_page":"308","last_page":"310"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quaternary-ammonium-salts","display_name":"quaternary ammonium compounds","score":0.8759999871253967},{"id":"https://openalex.org/keywords/fungicidal-activity","display_name":"fungicidal activity","score":0.9810000061988831},{"id":"https://openalex.org/keywords/disinfectants","display_name":"disinfectants","score":0.7799999713897705},{"id":"https://openalex.org/keywords/benzalkonium-chloride","display_name":"benzalkonium chloride","score":0.9490000009536743},{"id":"https://openalex.org/keywords/chlorhexidine-gluconate","display_name":"chlorhexidine gluconate","score":0.9909999966621399},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9330000281333923},{"id":"https://openalex.org/keywords/candida-tropicalis","display_name":"Candida tropicalis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/candida-parapsilosis","display_name":"Candida parapsilosis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/aspergillus-niger","display_name":"Aspergillus niger","score":0.9890000224113464},{"id":"https://openalex.org/keywords/aspergillus-terreus","display_name":"Aspergillus terreus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/trichophyton-rubrum","display_name":"Trichophyton rubrum","score":1.0},{"id":"https://openalex.org/keywords/antifungal-agents","display_name":"antifungal agents","score":0.7440000176429749},{"id":"https://openalex.org/keywords/counterion-effects","display_name":"counterion effects","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C2779870022","wikidata":"https://www.wikidata.org/wiki/Q190901","display_name":"Ammonium","level":2,"score":0.8218958973884583},{"id":"https://openalex.org/C2776371256","wikidata":"https://www.wikidata.org/wiki/Q12370","display_name":"Salt (chemistry)","level":2,"score":0.802757978439331},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.7344492673873901},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.6948163509368896},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6822287440299988},{"id":"https://openalex.org/C2778197767","wikidata":"https://www.wikidata.org/wiki/Q423820","display_name":"Ammonium phosphate","level":3,"score":0.4891274571418762},{"id":"https://openalex.org/C160464908","wikidata":"https://www.wikidata.org/wiki/Q26185","display_name":"Quaternary","level":2,"score":0.436308890581131},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.3715198040008545},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.34441953897476196},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0993620753288269},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C2780560099","wikidata":"https://www.wikidata.org/wiki/Q83323","display_name":"Fertilizer","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000644","descriptor_name":"Quaternary Ammonium Compounds","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004202","descriptor_name":"Disinfectants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1248/bpb.19.308","doi":"https://doi.org/10.1248/bpb.19.308","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.19.308","pdf_url":"https://www.jstage.jst.go.jp/article/bpb1993/19/2/19_2_308/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},{"id":"pmid:8850330","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8850330","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological & pharmaceutical bulletin","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1248/bpb.19.308","doi":"https://doi.org/10.1248/bpb.19.308","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.19.308","pdf_url":"https://www.jstage.jst.go.jp/article/bpb1993/19/2/19_2_308/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2080201744.pdf","grobid_xml":"https://content.openalex.org/works/W2080201744.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2126321901","https://openalex.org/W2395293963","https://openalex.org/W2428653902","https://openalex.org/W4221100064","https://openalex.org/W3125172901","https://openalex.org/W2357045787","https://openalex.org/W2387706549","https://openalex.org/W2370377029","https://openalex.org/W4240275678","https://openalex.org/W2418780199"],"abstract_inverted_index":{"We":[0],"synthesized":[1],"a":[2,24,189,197,201],"new":[3,225],"quaternary":[4],"ammonium":[5],"salt,":[6],"N-alkyl-N-2-hydroxyethyl-N,":[7],"N-dimethylammonium":[8],"butyl":[9,26,190],"phosphate":[10,27,191],"(ABP)":[11],"that":[12,236],"does":[13],"not":[14],"precipitate":[15],"in":[16,55,72,140,146],"the":[17,48,103,124,186,194],"presence":[18],"of":[19,51,75,138,241],"anionic":[20],"surfactants":[21],"by":[22],"incorporating":[23],"paired":[25],"anion":[28,192,199],"into":[29],"cationic":[30],"surfactants.":[31],"ABP":[32,52,99,126,228],"showed":[33,102,127,155],"much":[34],"greater":[35],"bactericidal":[36],"activities":[37],"and":[38,64,95,100,110,113,134,145,151,164,173,193,206,219,244],"antirusting":[39],"effects":[40,50,69,105,115,130,157,213,235],"than":[41],"benzalkonium":[42],"chloride":[43,198],"(BAC).":[44],"In":[45],"this":[46,184],"study,":[47],"fungicidal":[49,129,234],"were":[53,70],"evaluated":[54,71],"comparison":[56],"with":[57,120],"common":[58],"disinfectants":[59],"[BAC,":[60],"chlorhexidine":[61],"digluconate":[62],"(CHX)":[63],"alkyldiaminoethylglycine":[65],"hydrochloride":[66],"(ADE)].":[67],"Fungicidal":[68],"10":[73],"strains":[74],"6":[76],"fungal":[77],"species,":[78],"namely,":[79],"3":[80,117],"Candida":[81,84,87],"albicans,":[82,119],"2":[83,92,107,135,165],"tropicalis,":[85],"1":[86,89,96,162,220],"parapsilosis,":[88,112],"Aspergillus":[90,93],"niger,":[91],"terreus,":[94],"Trichophyton":[97],"rubrum.":[98],"BAC":[101,154],"same":[104],"on":[106,116,214],"C.":[108,111,118],"tropicalis":[109],"similar":[114],"slight":[121],"differences":[122],"among":[123],"strains.":[125],"quick":[128],"against":[131,158],"A.":[132,136,159,166,215],"niger":[133,160,216],"terreus":[137,167],"molds":[139],"30":[141,169],"min":[142,148,170],"at":[143,149,161,168,171,217,222],"0.1%":[144,218],"15":[147],"0.2":[150,172],"0.4%,":[152,174],"but":[153],"slow":[156],"h":[163,221],"respectively.":[175],"There":[176],"is":[177,229],"one":[178],"factor,":[179],"which":[180],"may":[181],"have":[182,232],"caused":[183],"difference:":[185],"former":[187],"had":[188,196],"latter":[195],"as":[200],"counter":[202],"ion.":[203],"BAC,":[204,242],"CHX":[205,243],"ADE":[207],"needed":[208],"24h":[209],"to":[210,231,239],"cause":[211],"notable":[212],"0.2%.":[223],"The":[224],"synthetic":[226],"anti-rust":[227],"considered":[230],"sufficient":[233],"are":[237],"comparable":[238],"those":[240],"ADE.":[245]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}