{"id":"https://openalex.org/W2080151794","doi":"https://doi.org/10.1249/01.mss.0000353511.09224.dd","title":"Changes In PPARd Protein Content Following Acute Aerobic Exercise In Human Vastus Lateralis Muscle.","display_name":"Changes In PPARd Protein Content Following Acute Aerobic Exercise In Human Vastus Lateralis Muscle.","publication_year":2009,"publication_date":"2009-05-01","ids":{"openalex":"https://openalex.org/W2080151794","doi":"https://doi.org/10.1249/01.mss.0000353511.09224.dd","mag":"2080151794"},"language":"en","primary_location":{"id":"doi:10.1249/01.mss.0000353511.09224.dd","doi":"https://doi.org/10.1249/01.mss.0000353511.09224.dd","is_oa":false,"landing_page_url":"https://doi.org/10.1249/01.mss.0000353511.09224.dd","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003672291","display_name":"Nicholas Perry Greene","orcid":"https://orcid.org/0000-0001-9621-2005","observed_orcids":["https://orcid.org/0000-0001-9621-2005"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas P. Greene","raw_affiliation_strings":["(No relationships reported)","(Sponsor: Stephen F. Crouse, FACSM)","Email: [email\u00a0protected]","Texas A&M University, College Station, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(No relationships reported)","institution_ids":[]},{"raw_affiliation_string":"(Sponsor: Stephen F. Crouse, FACSM)","institution_ids":[]},{"raw_affiliation_string":"Email: [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Texas A&M University, College Station, TX","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049073072","display_name":"Mats Inge Nilsson","orcid":"https://orcid.org/0000-0001-5656-5578","observed_orcids":["https://orcid.org/0000-0001-5656-5578"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mats I. Nilsson","raw_affiliation_strings":["(No relationships reported)","(Sponsor: Stephen F. Crouse, FACSM)","Email: [email\u00a0protected]","Texas A&M University, College Station, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(No relationships reported)","institution_ids":[]},{"raw_affiliation_string":"(Sponsor: Stephen F. Crouse, FACSM)","institution_ids":[]},{"raw_affiliation_string":"Email: [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Texas A&M University, College Station, TX","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112373627","display_name":"Brad S. Lambert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brad S. Lambert","raw_affiliation_strings":["(No relationships reported)","(Sponsor: Stephen F. Crouse, FACSM)","Email: [email\u00a0protected]","Texas A&M University, College Station, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(No relationships reported)","institution_ids":[]},{"raw_affiliation_string":"(Sponsor: Stephen F. Crouse, FACSM)","institution_ids":[]},{"raw_affiliation_string":"Email: [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Texas A&M University, College Station, TX","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072072183","display_name":"Steven E. Reichman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven E. Reichman","raw_affiliation_strings":["(No relationships reported)","(Sponsor: Stephen F. Crouse, FACSM)","Email: [email\u00a0protected]","Texas A&M University, College Station, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(No relationships reported)","institution_ids":[]},{"raw_affiliation_string":"(Sponsor: Stephen F. Crouse, FACSM)","institution_ids":[]},{"raw_affiliation_string":"Email: [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Texas A&M University, College Station, TX","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026323332","display_name":"James D. Fluckey","orcid":"https://orcid.org/0000-0003-1231-0412","observed_orcids":["https://orcid.org/0000-0003-1231-0412"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James D. Fluckey","raw_affiliation_strings":["(No relationships reported)","(Sponsor: Stephen F. Crouse, FACSM)","Email: [email\u00a0protected]","Texas A&M University, College Station, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(No relationships reported)","institution_ids":[]},{"raw_affiliation_string":"(Sponsor: Stephen F. Crouse, FACSM)","institution_ids":[]},{"raw_affiliation_string":"Email: [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Texas A&M University, College Station, TX","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058567665","display_name":"Stephen F. Crouse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen F. Crouse","raw_affiliation_strings":["Sponsor: Stephen F. Crouse, FACSM)","(No relationships reported)","Email: [email\u00a0protected]","Texas A&M University, College Station, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sponsor: Stephen F. Crouse, FACSM)","institution_ids":[]},{"raw_affiliation_string":"(No relationships reported)","institution_ids":[]},{"raw_affiliation_string":"Email: [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Texas A&M University, College Station, TX","institution_ids":["https://openalex.org/I91045830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I91045830"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16694158,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"5","first_page":"78","last_page":"78"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ppardelta","display_name":"PPAR\u03b4","score":0.9380000233650208},{"id":"https://openalex.org/keywords/ppargamma","display_name":"PPAR\u03b3","score":0.5979999899864197},{"id":"https://openalex.org/keywords/acute-aerobic-exercise","display_name":"acute aerobic exercise","score":0.8939999938011169},{"id":"https://openalex.org/keywords/vastus-lateralis","display_name":"vastus lateralis","score":0.9290000200271606},{"id":"https://openalex.org/keywords/protein-expression","display_name":"protein expression","score":0.6190000176429749},{"id":"https://openalex.org/keywords/exercise-training","display_name":"exercise training","score":0.3919999897480011},{"id":"https://openalex.org/keywords/glucose-and-lipid-metabolism","display_name":"glycolipid metabolism","score":0.7179999947547913}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7661542296409607},{"id":"https://openalex.org/C2781464450","wikidata":"https://www.wikidata.org/wiki/Q839144","display_name":"Treadmill","level":2,"score":0.6577432155609131},{"id":"https://openalex.org/C99476002","wikidata":"https://www.wikidata.org/wiki/Q42297","display_name":"Analysis of variance","level":2,"score":0.5395362377166748},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.51072096824646},{"id":"https://openalex.org/C103038586","wikidata":"https://www.wikidata.org/wiki/Q1152037","display_name":"Aerobic exercise","level":2,"score":0.5044904947280884},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.40636634826660156},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.355515718460083}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1249/01.mss.0000353511.09224.dd","doi":"https://doi.org/10.1249/01.mss.0000353511.09224.dd","is_oa":false,"landing_page_url":"https://doi.org/10.1249/01.mss.0000353511.09224.dd","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine &amp; Science in Sports &amp; Exercise","raw_type":"journal-article"},{"id":"pmh:oai:digitalcommons.wku.edu:ijesab-1025","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.wku.edu/ijesab/vol2/iss1/23","pdf_url":null,"source":{"id":"https://openalex.org/S4377196460","display_name":"TopSCHOLAR (Western Kentucky University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94339441","host_organization_name":"Western Kentucky University","host_organization_lineage":["https://openalex.org/I94339441"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Exercise Science: Conference Proceedings","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2146957228","https://openalex.org/W1558803334","https://openalex.org/W4366606761","https://openalex.org/W2255430195","https://openalex.org/W2290214200","https://openalex.org/W2474777679","https://openalex.org/W2734334317","https://openalex.org/W2898992673","https://openalex.org/W2806795504","https://openalex.org/W2600223504"],"abstract_inverted_index":{"PPARd":[0,35,42,55,168,195,232,251],"is":[1,46,253],"a":[2,20,150,157,260,281],"transcription":[3],"factor":[4],"which":[5],"functions":[6],"in":[7,54,65,76,171,204,229,255,270,283],"the":[8,39,77,115,124,131,165,284,295],"regulation":[9],"of":[10,41,62,160,231,263,272,286,315,319],"lipid":[11],"and":[12,15,72,87,98,117,140,187,304,311],"glucose":[13],"metabolism,":[14],"may":[16],"be":[17],"implicated":[18],"as":[19,189],"therapeutic":[21],"target":[22,158],"for":[23,110,156,289,301],"several":[24],"metabolic":[25],"diseases.":[26],"Exercise":[27],"training":[28],"has":[29],"previously":[30,205],"been":[31],"shown":[32],"to":[33,43,106,114,118,137],"increase":[34],"protein":[36,56,169],"content,":[37],"but":[38],"response":[40],"acute":[44,60,138,202,278],"exercise":[45,64,109,139,166,203,236,265,279],"not":[47],"yet":[48],"understood.":[49],"PURPOSE:":[50],"To":[51],"explore":[52],"changes":[53],"content":[57,170,196],"following":[58,201,235,259],"an":[59],"bout":[61,262],"aerobic":[63,264],"untrained":[66],"obese":[67,207,257],"adults.":[68],"METHODS:":[69],"8":[70],"men":[71],"4":[73],"women":[74],"participated":[75],"study.":[78,125],"Subjects'":[79],"mean":[80],"age,":[81],"weight,":[82],"VO2MAX":[83,155],"(Bruce":[84],"treadmill":[85,152],"GXT),":[86],"body":[88,100],"composition":[89],"(DEXA)":[90],"were":[91,104,128,147,181],"44":[92],"yr,":[93],"93.2":[94],"kg,":[95],"28.2":[96],"mL/kg/min,":[97],"40.5%":[99],"fat,":[101],"respectively.":[102],"Subjects":[103,146],"asked":[105],"refrain":[107],"from":[108,130],"1":[111],"week":[112],"prior":[113,136],"experiment":[116],"maintain":[119],"normal":[120],"dietary":[121],"habits":[122],"during":[123,164],"Muscle":[126],"biopsies":[127],"obtained":[129],"vastus":[132],"lateralis":[133],"3":[134],"days":[135],"again":[141],"24":[142,199],"hours":[143,200],"after":[144],"exercise.":[145],"exercised":[148,214,242],"on":[149],"motorized":[151],"at":[153,307],"70%":[154],"duration":[159],"400kcal":[161],"energy":[162],"expenditure":[163],"session.":[167],"biopsied":[172],"tissue":[173],"was":[174,197,292],"determined":[175],"by":[176,183,294],"Western":[177],"blot":[178],"analysis.":[179],"Data":[180],"analyzed":[182],"repeated":[184],"measures":[185],"ANOVA":[186],"expressed":[188],"means":[190],"\u00b1":[191,211,216,239,244],"standard":[192],"error.":[193],"RESULTS:":[194],"enhanced":[198,254],"untrained,":[206,256],"adults":[208,258],"(unexercised":[209,237],"1.54":[210],"0.38":[212],"vs.":[213,241],"2.30":[215],"0.39":[217],"arbitrary":[218],"units,":[219],"P":[220],"<":[221],"0.05).":[222],"Gel":[223],"mobility":[224],"shift":[225],"indicated":[226],"no":[227,267],"difference":[228],"activity":[230],"(phosphorylated:":[233],"total)":[234],"0.36":[238],"0.03":[240],"0.34":[243],"0.04).":[245],"CONCLUSION:":[246],"Our":[247],"study":[248],"shows":[249],"that":[250,277],"expression":[252,285],"single":[261],"with":[266],"relative":[268],"change":[269],"phosphorylation":[271],"PPARd.":[273,287],"These":[274],"data":[275],"indicate":[276],"plays":[280],"role":[282],"Funding":[288],"this":[290],"research":[291],"provided":[293],"Sydney":[296],"&":[297],"J.L.":[298],"Huffines":[299],"Institute":[300],"Sports":[302,320],"Medicine":[303,321],"Human":[305],"Performance":[306],"Texas":[308,313],"A&M":[309],"University":[310],"The":[312,316],"Chapter":[314],"American":[317],"College":[318]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}