{"id":"https://openalex.org/W2079977579","doi":"https://doi.org/10.1073/pnas.082115999","title":"Genes on chromosomes 1 and 13 have significant effects on Ascaris infection","display_name":"Genes on chromosomes 1 and 13 have significant effects on Ascaris infection","publication_year":2002,"publication_date":"2002-04-16","ids":{"openalex":"https://openalex.org/W2079977579","doi":"https://doi.org/10.1073/pnas.082115999","mag":"2079977579","pmid":"https://pubmed.ncbi.nlm.nih.gov/11960011","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/122804"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.082115999","doi":"https://doi.org/10.1073/pnas.082115999","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.082115999","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/122804","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108101465","display_name":"Sarah Williams\u2010Blangero","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"Sarah Williams-Blangero","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016947225","display_name":"John L. VandeBerg","orcid":"https://orcid.org/0000-0002-7087-979X","observed_orcids":["https://orcid.org/0000-0002-7087-979X"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"John L. VandeBerg","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108459781","display_name":"Janardan Subedi","orcid":"https://orcid.org/0000-0002-5117-230X","observed_orcids":["https://orcid.org/0000-0002-5117-230X"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"Janardan Subedi","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014998864","display_name":"Mary Jo Aivaliotis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"Mary Jo Aivaliotis","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dev Raj Rai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"Dev Raj Rai","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051980815","display_name":"Ram Prasad Upadhayay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"Ram Prasad Upadhayay","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110702356","display_name":"Bharat Jha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"Bharat Jha","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004538115","display_name":"John Blangero","orcid":"https://orcid.org/0000-0001-6250-5723","observed_orcids":["https://orcid.org/0000-0001-6250-5723"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I155028946","display_name":"Tribhuvan University","ror":"https://ror.org/02rg1r889","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946"]},{"id":"https://openalex.org/I4405260107","display_name":"Institute of Medicine","ror":"https://ror.org/038ymyw44","country_code":"NP","type":"education","lineage":["https://openalex.org/I155028946","https://openalex.org/I4405260107"]},{"id":"https://openalex.org/I83328450","display_name":"Miami University","ror":"https://ror.org/05nbqxr67","country_code":"US","type":"education","lineage":["https://openalex.org/I83328450"]}],"countries":["NP","US"],"is_corresponding":false,"raw_author_name":"John Blangero","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245; Southwest Regional Primate Research Center, P.O. Box 760549, San Antonio, TX 78245; Department of Sociology, Anthropology, and Gerontology, Miami University, Oxford, OH 45056; Jiri Helminth Project, Jiri 9, Dolakha District, Nepal; and Tribhuvan University Institute of Medicine, P.O. Box 1524, Majarajgung, Kathmandu, Nepal","institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I155028946","https://openalex.org/I4405260107","https://openalex.org/I83328450"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":10.7504,"has_fulltext":false,"cited_by_count":125,"citation_normalized_percentile":{"value":0.99332542,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"99","issue":"8","first_page":"5533","last_page":"5538"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.9312000274658203,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.9312000274658203,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.035599999129772186,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":0.013000000268220901,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ascaris-lumbricoides","display_name":"Ascaris lumbricoides","score":0.9940000176429749},{"id":"https://openalex.org/keywords/ascariasis","display_name":"ascariasis","score":0.7310000061988831},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.6729999780654907},{"id":"https://openalex.org/keywords/quantitative-trait-loci","display_name":"quantitative trait loci","score":0.746999979019165},{"id":"https://openalex.org/keywords/worm-burden","display_name":"worm burden","score":0.6340000033378601},{"id":"https://openalex.org/keywords/human-chromosome-1","display_name":"chromosome 1","score":0.6499999761581421},{"id":"https://openalex.org/keywords/chromosome-13","display_name":"chromosome 13","score":1.0},{"id":"https://openalex.org/keywords/genetic-markers","display_name":"genetic markers","score":0.5789999961853027},{"id":"https://openalex.org/keywords/human-helminth-infection","display_name":"human helminth infection","score":0.4909999966621399},{"id":"https://openalex.org/keywords/genome-scan","display_name":"genome scan","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C2777364306","wikidata":"https://www.wikidata.org/wiki/Q468771","display_name":"Ascaris lumbricoides","level":3,"score":0.8192814588546753},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8166224956512451},{"id":"https://openalex.org/C2780492224","wikidata":"https://www.wikidata.org/wiki/Q310838","display_name":"Ascaris","level":3,"score":0.8114683628082275},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.663489043712616},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5851636528968811},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5843603610992432},{"id":"https://openalex.org/C142870003","wikidata":"https://www.wikidata.org/wiki/Q843863","display_name":"Genetic linkage","level":3,"score":0.5083982348442078},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.4964030385017395},{"id":"https://openalex.org/C2778830712","wikidata":"https://www.wikidata.org/wiki/Q5185","display_name":"Nematode","level":2,"score":0.47887107729911804},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.4455410838127136},{"id":"https://openalex.org/C31266012","wikidata":"https://www.wikidata.org/wiki/Q6554340","display_name":"Linkage (software)","level":3,"score":0.4255450963973999},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4041227400302887},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.255615770816803},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.20076829195022583},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08731743693351746},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0801762044429779},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001196","descriptor_name":"Ascariasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001196","descriptor_name":"Ascariasis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001200","descriptor_name":"Ascaris","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002878","descriptor_name":"Chromosomes, Human, Pair 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002882","descriptor_name":"Chromosomes, Human, Pair 13","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008040","descriptor_name":"Genetic Linkage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008126","descriptor_name":"Lod Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009390","descriptor_name":"Nepal","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D010270","descriptor_name":"Parasite Egg Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015894","descriptor_name":"Genome, Human","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1073/pnas.082115999","doi":"https://doi.org/10.1073/pnas.082115999","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.082115999","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:122804","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/122804","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:11960011","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11960011","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:122804","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/122804","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7246000170707703,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.40450000762939453,"display_name":"Zero hunger"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2158315337","display_name":"Quantitative Trait Locus Mapping in Human Pedigrees","funder_award_id":"R37MH059490","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G2524895636","display_name":null,"funder_award_id":"AI44406","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4049533224","display_name":"Genetics of Susceptibility to Helminthic Infection","funder_award_id":"R01AI037091","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4905894037","display_name":"A GENOME SCAN FOR SUSCEPTIBILITY TO HELMINTHIC INFECTION","funder_award_id":"R21AI044406","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7727343774","display_name":"A Genome Scan for Susceptibility to Helminthic Infection","funder_award_id":"R01AI044406","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7852197243","display_name":null,"funder_award_id":"MH59490","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G8952902939","display_name":"QUANTITATIVE TRAIT LOCUS MAPPING IN HUMAN PEDIGREES","funder_award_id":"R01MH059490","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W101171454","https://openalex.org/W1510548575","https://openalex.org/W1545987815","https://openalex.org/W1906384791","https://openalex.org/W1910631423","https://openalex.org/W1965385111","https://openalex.org/W1975162165","https://openalex.org/W1975564933","https://openalex.org/W1978141065","https://openalex.org/W1980789378","https://openalex.org/W2001879193","https://openalex.org/W2015045000","https://openalex.org/W2019635739","https://openalex.org/W2035650962","https://openalex.org/W2042103448","https://openalex.org/W2044267317","https://openalex.org/W2044769864","https://openalex.org/W2053540315","https://openalex.org/W2053938906","https://openalex.org/W2054415380","https://openalex.org/W2071903281","https://openalex.org/W2077218313","https://openalex.org/W2103474468","https://openalex.org/W2115335486","https://openalex.org/W2122391004","https://openalex.org/W2127971170","https://openalex.org/W2152330468","https://openalex.org/W2158488526","https://openalex.org/W2170666854","https://openalex.org/W2327420058","https://openalex.org/W2400352759","https://openalex.org/W2412685243","https://openalex.org/W2414609135","https://openalex.org/W4231990549"],"related_works":["https://openalex.org/W2106080259","https://openalex.org/W1906384791","https://openalex.org/W2551644037","https://openalex.org/W1971670981","https://openalex.org/W2073261798","https://openalex.org/W2014744674","https://openalex.org/W6974082660","https://openalex.org/W2802764742","https://openalex.org/W6954549861","https://openalex.org/W2046836371"],"abstract_inverted_index":{"Nematode":[0],"parasites":[1],"show":[2],"a":[3,68,112],"characteristic":[4],"aggregated":[5],"distribution":[6],"among":[7],"hosts.":[8],"This":[9,37,158],"observation":[10],"has":[11],"important":[12],"implications":[13],"for":[14,47,62,102,124],"pathogenesis,":[15],"immunology,":[16],"and":[17,28,144],"control":[18],"of":[19,26,42,64,67,107,119,137],"these":[20,32,86],"infections,":[21],"but":[22],"the":[23,40,43,73,91,103,134,160],"relative":[24],"roles":[25],"environment":[27],"genetics":[29],"in":[30,85,133,170,173],"determining":[31],"patterns":[33],"have":[34],"remained":[35],"uncertain.":[36],"paper":[38],"presents":[39],"results":[41],"first":[44,161],"genome":[45],"scan":[46],"susceptibility":[48,154],"to":[49,111,155],"infection":[50],"with":[51,149],"roundworm":[52],"(Ascaris":[53],"lumbricoides).":[54],"Data":[55],"on":[56,141,146,153],"375":[57],"genetic":[58,125],"markers":[59],"were":[60,122],"generated":[61],"each":[63],"444":[65,109],"members":[66],"genetically":[69],"isolated":[70],"Nepalese":[71],"population,":[72],"Jirels.":[74],"Ascaris":[75,156,171],"worm":[76],"burden":[77,172],"as":[78],"assessed":[79],"by":[80,89],"egg":[81],"counts":[82],"was":[83],"measured":[84],"same":[87],"individuals":[88,110],"using":[90],"Kato":[92],"Katz":[93],"thick":[94],"smear":[95],"method.":[96],"The":[97],"extensive":[98],"genealogical":[99],"data":[100],"available":[101],"population":[104],"allowed":[105],"assignment":[106],"all":[108],"single":[113],"pedigree":[114],"that":[115,121,163],"contained":[116],"6,209":[117],"pairs":[118],"relatives":[120],"informative":[123],"analysis.":[126],"A":[127],"variance":[128],"components":[129],"linkage":[130],"analysis":[131],"resulted":[132],"unequivocal":[135],"localization":[136],"two":[138],"genes":[139],"(one":[140],"chromosome":[142,147],"1":[143],"another":[145],"13)":[148],"clear,":[150],"significant":[151],"effects":[152],"infection.":[157],"is":[159],"evidence":[162],"individual":[164],"quantitative":[165],"trait":[166],"loci":[167],"influence":[168],"variation":[169],"humans.":[174]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
