{"id":"https://openalex.org/W2079966941","doi":"https://doi.org/10.2196/jmir.6.3.e35","title":"Tackling Publication Bias and Selective Reporting in Health Informatics Research: Register your eHealth Trials in the International eHealth Studies Registry","display_name":"Tackling Publication Bias and Selective Reporting in Health Informatics Research: Register your eHealth Trials in the International eHealth Studies Registry","publication_year":2004,"publication_date":"2004-09-30","ids":{"openalex":"https://openalex.org/W2079966941","doi":"https://doi.org/10.2196/jmir.6.3.e35","mag":"2079966941","pmid":"https://pubmed.ncbi.nlm.nih.gov/15471761","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1550610"},"language":"en","primary_location":{"id":"doi:10.2196/jmir.6.3.e35","doi":"https://doi.org/10.2196/jmir.6.3.e35","is_oa":true,"landing_page_url":"https://doi.org/10.2196/jmir.6.3.e35","pdf_url":"https://www.jmir.org/2004/3/e35/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.jmir.org/2004/3/e35/PDF","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032622638","display_name":"G\u00fcnther Eysenbach","orcid":"https://orcid.org/0000-0001-6479-5330","observed_orcids":["https://orcid.org/0000-0001-6479-5330"]},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Gunther Eysenbach","raw_affiliation_strings":["Centre for Global eHealth Innovation, Toronto, Canada","Department of Health Policy, Management and Evaluation Senior Scientist, Centre for Global eHealth Innovation University of Toronto University Health Network 190 Elizabeth Street Toronto ON M5G 2C4 Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Global eHealth Innovation, Toronto, Canada","institution_ids":[]},{"raw_affiliation_string":"Department of Health Policy, Management and Evaluation Senior Scientist, Centre for Global eHealth Innovation University of Toronto University Health Network 190 Elizabeth Street Toronto ON M5G 2C4 Canada","institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5032622638"],"corresponding_institution_ids":["https://openalex.org/I1325899441","https://openalex.org/I185261750"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":null,"has_fulltext":true,"cited_by_count":34,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"3","first_page":"e35","last_page":"e35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13607","display_name":"Academic Publishing and Open Access","score":0.03400000184774399,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11937","display_name":"Research Data Management Practices","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1710","display_name":"Information Systems"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/publication-bias","display_name":"publication bias","score":0.9850000143051147},{"id":"https://openalex.org/keywords/selective-reporting-bias","display_name":"selective reporting","score":0.996999979019165},{"id":"https://openalex.org/keywords/clinical-trial-registration","display_name":"clinical trial registration","score":0.7350000143051147},{"id":"https://openalex.org/keywords/health-informatics-research","display_name":"health informatics research","score":0.7940000295639038},{"id":"https://openalex.org/keywords/non-randomized-studies","display_name":"non-randomized studies","score":0.8299999833106995},{"id":"https://openalex.org/keywords/research-duplication","display_name":"research duplication","score":0.4690000116825104}],"concepts":[{"id":"https://openalex.org/C202645933","wikidata":"https://www.wikidata.org/wiki/Q4930","display_name":"eHealth","level":3,"score":0.9676652550697327},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.6268773078918457},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.5702285170555115},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5234891176223755},{"id":"https://openalex.org/C191630685","wikidata":"https://www.wikidata.org/wiki/Q4027615","display_name":"Informatics","level":2,"score":0.48990291357040405},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4708033800125122},{"id":"https://openalex.org/C108827166","wikidata":"https://www.wikidata.org/wiki/Q175975","display_name":"Internet privacy","level":1,"score":0.4208545684814453},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31638145446777344},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.2798435091972351},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.26993390917778015},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.21337798237800598},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.18689894676208496},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.1327555775642395},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006262","descriptor_name":"Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011643","descriptor_name":"Publishing","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D017594","descriptor_name":"Publication Bias","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D048088","descriptor_name":"Informatics","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.2196/jmir.6.3.e35","doi":"https://doi.org/10.2196/jmir.6.3.e35","is_oa":true,"landing_page_url":"https://doi.org/10.2196/jmir.6.3.e35","pdf_url":"https://www.jmir.org/2004/3/e35/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:562535","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1550610","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:15471761","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15471761","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical Internet research","raw_type":"Editorial"},{"id":"pmh:oai:localhost:1807/4718","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/4718","pdf_url":null,"source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},{"id":"pmh:oai:utoronto.scholaris.ca:1807/4718","doi":null,"is_oa":true,"landing_page_url":"https://utoronto.scholaris.ca/bitstreams/c2bbfa52-a5ab-4a4b-af29-f9278831d376/download","pdf_url":null,"source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.2196/jmir.6.3.e35","doi":"https://doi.org/10.2196/jmir.6.3.e35","is_oa":true,"landing_page_url":"https://doi.org/10.2196/jmir.6.3.e35","pdf_url":"https://www.jmir.org/2004/3/e35/PDF","source":{"id":"https://openalex.org/S17147534","display_name":"Journal of Medical Internet Research","issn_l":"1438-8871","issn":["1438-8871","1439-4456"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","fnege-4","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Internet Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Partnerships for the goals","score":0.550000011920929,"id":"https://metadata.un.org/sdg/17"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2079966941.pdf","grobid_xml":"https://content.openalex.org/works/W2079966941.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1486263930","https://openalex.org/W1504095083","https://openalex.org/W1887056411","https://openalex.org/W1966057123","https://openalex.org/W1994151990","https://openalex.org/W2034572160","https://openalex.org/W2090760643","https://openalex.org/W2095225831","https://openalex.org/W2113097201","https://openalex.org/W2133774931","https://openalex.org/W2140521029","https://openalex.org/W2146962585","https://openalex.org/W2163756514","https://openalex.org/W2169201348","https://openalex.org/W2971461972","https://openalex.org/W4246599781"],"related_works":["https://openalex.org/W4293219740","https://openalex.org/W2779375218","https://openalex.org/W2059447862","https://openalex.org/W7098689851","https://openalex.org/W1956249145","https://openalex.org/W2143548104","https://openalex.org/W2560217268","https://openalex.org/W2015157752","https://openalex.org/W2034556909","https://openalex.org/W1992108332"],"abstract_inverted_index":{"Beginning":[0],"in":[1,25,78],"July":[2],"2005,":[3],"several":[4],"major":[5],"medical":[6],"journals,":[7],"including":[8],"the":[9,79,96,112],"Journal":[10],"of":[11,43,73,81,98,104,117,130,141],"Medical":[12],"Internet":[13],"Research,":[14],"will":[15,110,125],"only":[16],"consider":[17],"trials":[18,74],"for":[19,57,101,115],"publication":[20,36],"that":[21],"have":[22],"been":[23,68],"registered":[24],"a":[26,60,105],"trial":[27,49],"registry":[28],"before":[29],"they":[30],"started.":[31],"This":[32],"is":[33],"to":[34,39,52],"reduce":[35],"bias":[37],"and":[38,84,138],"prevent":[40],"selective":[41],"reporting":[42],"positive":[44],"outcomes.":[45],"As":[46],"existing":[47],"clinical":[48],"registers":[50],"seem":[51],"be":[53],"unsuitable":[54],"or":[55],"suboptimal":[56],"eHealth":[58,63,88,118,132],"studies,":[59],"free":[61],"International":[62,87],"Study":[64,89],"Registry":[65],"(IESR)":[66],"has":[67],"set":[69],"up,":[70],"allowing":[71],"registration":[72,103,116],"(including":[75],"non-randomized":[76],"studies)":[77],"field":[80],"health":[82],"informatics":[83],"assigning":[85],"an":[86,122,127],"Number":[90],"(IESN).":[91],"The":[92],"IESR":[93,109],"should":[94],"meet":[95],"requirements":[97],"journal":[99],"editors":[100],"a-priori":[102],"study.":[106],"We":[107],"hope":[108],"become":[111,126],"preferred":[113],"choice":[114],"studies":[119],"and,":[120],"as":[121],"secondary":[123],"benefit,":[124],"international":[128],"repository":[129],"ongoing":[131],"projects,":[133],"thereby":[134],"enhancing":[135],"global":[136],"collaboration":[137],"reducing":[139],"duplication":[140],"effort.":[142]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}