{"id":"https://openalex.org/W2079942338","doi":"https://doi.org/10.1016/j.bbr.2013.11.015","title":"BDNF-stimulated intracellular signalling mechanisms underlie exercise-induced improvement in spatial memory in the male Wistar rat","display_name":"BDNF-stimulated intracellular signalling mechanisms underlie exercise-induced improvement in spatial memory in the male Wistar rat","publication_year":2013,"publication_date":"2013-11-21","ids":{"openalex":"https://openalex.org/W2079942338","doi":"https://doi.org/10.1016/j.bbr.2013.11.015","mag":"2079942338","pmid":"https://pubmed.ncbi.nlm.nih.gov/24269499"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbr.2013.11.015","doi":"https://doi.org/10.1016/j.bbr.2013.11.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbr.2013.11.015","pdf_url":null,"source":{"id":"https://openalex.org/S81474683","display_name":"Behavioural Brain Research","issn_l":"0166-4328","issn":["0166-4328","1872-7549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioural Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.tara.tcd.ie/bitstream/2262/71493/1/Bechara-BDNF-stimulated%20intracellular%20signalli.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047345745","display_name":"Ranya G. Bechara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Ranya G. Bechara","raw_affiliation_strings":["Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland; Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland. Electronic address: becharar@tcd.ie","Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland","Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland; Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland. Electronic address: becharar@tcd.ie","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007612534","display_name":"Ronan Lyne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Ronan Lyne","raw_affiliation_strings":["Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009560918","display_name":"Aine Marie Kelly","orcid":"https://orcid.org/0000-0002-9255-0848","observed_orcids":["https://orcid.org/0000-0002-9255-0848"]},"institutions":[{"id":"https://openalex.org/I205274468","display_name":"Trinity College Dublin","ror":"https://ror.org/02tyrky19","country_code":"IE","type":"education","lineage":["https://openalex.org/I205274468"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"\u00c1ine M. Kelly","raw_affiliation_strings":["Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland; Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland","Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland","Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland; Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Department of Physiology, School of Medicine, University of Dublin, Trinity College, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]},{"raw_affiliation_string":"Trinity College Institute of Neuroscience, University of Dublin, Trinity College, Dublin 2, Ireland","institution_ids":["https://openalex.org/I205274468"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5047345745"],"corresponding_institution_ids":["https://openalex.org/I205274468"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":1.2791,"has_fulltext":true,"cited_by_count":67,"citation_normalized_percentile":{"value":0.76683734,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"275","issue":null,"first_page":"297","last_page":"306"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.7089999914169312,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.7089999914169312,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.15320000052452087,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.12319999933242798,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-derived-neurotrophic-factor","display_name":"brain-derived neurotrophic factor","score":0.925000011920929},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.7549999952316284},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.9850000143051147},{"id":"https://openalex.org/keywords/spatial-learning","display_name":"spatial learning","score":0.8550000190734863},{"id":"https://openalex.org/keywords/dentate-gyrus","display_name":"dentate gyrus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.7900000214576721},{"id":"https://openalex.org/keywords/trkb","display_name":"TrkB","score":0.7210000157356262},{"id":"https://openalex.org/keywords/erk1","display_name":"ERK1","score":0.824999988079071},{"id":"https://openalex.org/keywords/synapsin-1","display_name":"synapsin-1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/intracerebroventricular-injection","display_name":"intracerebroventricular administration","score":0.8679999709129333},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.7839999794960022},{"id":"https://openalex.org/keywords/synaptic-transmission","display_name":"synaptic transmission","score":0.8500000238418579}],"concepts":[{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.927796483039856},{"id":"https://openalex.org/C50493954","wikidata":"https://www.wikidata.org/wiki/Q18031806","display_name":"Synapsin I","level":5,"score":0.7943617105484009},{"id":"https://openalex.org/C2778790584","wikidata":"https://www.wikidata.org/wiki/Q123045","display_name":"Brain-derived neurotrophic factor","level":4,"score":0.6791620254516602},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6351965665817261},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.6030710339546204},{"id":"https://openalex.org/C160539049","wikidata":"https://www.wikidata.org/wiki/Q3064187","display_name":"Neurotrophic factors","level":3,"score":0.5495294332504272},{"id":"https://openalex.org/C97124661","wikidata":"https://www.wikidata.org/wiki/Q14897782","display_name":"Tropomyosin receptor kinase B","level":4,"score":0.4533774256706238},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.43216636776924133},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4256880283355713},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4123947322368622},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.31350845098495483},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25854915380477905},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.12869665026664734},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.0},{"id":"https://openalex.org/C148785051","wikidata":"https://www.wikidata.org/wiki/Q671136","display_name":"Synaptic vesicle","level":4,"score":0.0},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001973","descriptor_name":"Bromodeoxyuridine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010805","descriptor_name":"Physical Conditioning, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011189","descriptor_name":"Potassium Chloride","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016704","descriptor_name":"Synapsins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018891","descriptor_name":"Dentate Gyrus","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D018891","descriptor_name":"Dentate Gyrus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018891","descriptor_name":"Dentate Gyrus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D020813","descriptor_name":"Receptor, trkB","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020813","descriptor_name":"Receptor, trkB","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065852","descriptor_name":"Spatial Memory","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D065852","descriptor_name":"Spatial Memory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D065853","descriptor_name":"Spatial Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.bbr.2013.11.015","doi":"https://doi.org/10.1016/j.bbr.2013.11.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbr.2013.11.015","pdf_url":null,"source":{"id":"https://openalex.org/S81474683","display_name":"Behavioural Brain Research","issn_l":"0166-4328","issn":["0166-4328","1872-7549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioural Brain Research","raw_type":"journal-article"},{"id":"pmid:24269499","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24269499","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Behavioural brain research","raw_type":"Journal Article"},{"id":"pmh:oai:tara.tcd.ie:2262/71493","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2262/71493","pdf_url":"https://www.tara.tcd.ie/bitstream/2262/71493/1/Bechara-BDNF-stimulated%20intracellular%20signalli.pdf","source":{"id":"https://openalex.org/S4306400387","display_name":"Trinity's Access to Research Output (TARA) (Trinity College Dublin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205274468","host_organization_name":"Trinity College Dublin","host_organization_lineage":["https://openalex.org/I205274468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:http://www.rian.ie/103934/","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2262/71493","pdf_url":null,"source":{"id":"https://openalex.org/S4306400033","display_name":"Arrow@dit (Dublin Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210144925","host_organization_name":"Technological University Dublin","host_organization_lineage":["https://openalex.org/I4210144925"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bechara RG, Lyne R, Kelly AM, BDNF-stimulated intracellular signalling mechanisms underlie exercise-induced improvement in spatial memory in the male Wistar rat., Behavioural Brain Research, 2014","raw_type":"Journal article"}],"best_oa_location":{"id":"pmh:oai:tara.tcd.ie:2262/71493","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2262/71493","pdf_url":"https://www.tara.tcd.ie/bitstream/2262/71493/1/Bechara-BDNF-stimulated%20intracellular%20signalli.pdf","source":{"id":"https://openalex.org/S4306400387","display_name":"Trinity's Access to Research Output (TARA) (Trinity College Dublin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205274468","host_organization_name":"Trinity College Dublin","host_organization_lineage":["https://openalex.org/I205274468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2079942338.pdf","grobid_xml":"https://content.openalex.org/works/W2079942338.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W170973748","https://openalex.org/W1505414983","https://openalex.org/W1528643139","https://openalex.org/W1552458995","https://openalex.org/W1851485572","https://openalex.org/W1970516662","https://openalex.org/W1978668014","https://openalex.org/W1989049076","https://openalex.org/W1989876752","https://openalex.org/W1991000015","https://openalex.org/W1991856249","https://openalex.org/W1992790917","https://openalex.org/W1995188451","https://openalex.org/W1998096024","https://openalex.org/W2003665687","https://openalex.org/W2011583477","https://openalex.org/W2012438895","https://openalex.org/W2013045480","https://openalex.org/W2019814990","https://openalex.org/W2032690257","https://openalex.org/W2033333756","https://openalex.org/W2034758657","https://openalex.org/W2043106016","https://openalex.org/W2043610928","https://openalex.org/W2051556001","https://openalex.org/W2056798963","https://openalex.org/W2060532219","https://openalex.org/W2063849763","https://openalex.org/W2070037297","https://openalex.org/W2070820832","https://openalex.org/W2078945917","https://openalex.org/W2079472132","https://openalex.org/W2084719211","https://openalex.org/W2092519903","https://openalex.org/W2103752895","https://openalex.org/W2110341145","https://openalex.org/W2117820491","https://openalex.org/W2118977349","https://openalex.org/W2119757776","https://openalex.org/W2122117563","https://openalex.org/W2122586715","https://openalex.org/W2124806566","https://openalex.org/W2128635872","https://openalex.org/W2130941610","https://openalex.org/W2131196982","https://openalex.org/W2154684087","https://openalex.org/W2154727263","https://openalex.org/W2163006694","https://openalex.org/W2163752265","https://openalex.org/W2163815564"],"related_works":["https://openalex.org/W3201543307","https://openalex.org/W1998096024","https://openalex.org/W2119757776","https://openalex.org/W2944982230","https://openalex.org/W2009641399","https://openalex.org/W1990121428","https://openalex.org/W2060388037","https://openalex.org/W2100164454","https://openalex.org/W2802496934","https://openalex.org/W2088754913"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}