{"id":"https://openalex.org/W207981039","doi":null,"title":"Inflammation and lifestyle in cardiovascular medicine","display_name":"Inflammation and lifestyle in cardiovascular medicine","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W207981039","mag":"207981039"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:umu-36221","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36221","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36221","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079180613","display_name":"Jonas S. O. Andersson","orcid":"https://orcid.org/0000-0002-7939-0149","observed_orcids":["https://orcid.org/0000-0002-7939-0149"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jonas Andersson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7939-0149","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5079180613"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.45239999890327454,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.45239999890327454,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.3416000008583069,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.03909999877214432,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9679999947547913},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.8330000042915344},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8420000076293945},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.8809999823570251},{"id":"https://openalex.org/keywords/intracerebral-hemorrhage","display_name":"intracerebral hemorrhage","score":0.9950000047683716},{"id":"https://openalex.org/keywords/lifestyle-intervention","display_name":"lifestyle intervention","score":0.7739999890327454},{"id":"https://openalex.org/keywords/wellness-center","display_name":"wellness center","score":0.7889999747276306},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.7649999856948853},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8880000114440918},{"id":"https://openalex.org/keywords/impaired-glucose-tolerance","display_name":"impaired glucose tolerance","score":0.9160000085830688},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.7990000247955322},{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.8349999785423279},{"id":"https://openalex.org/keywords/plasminogen-activator-inhibitor-1","display_name":"plasminogen activator inhibitor-1","score":0.9549999833106995},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.6549999713897705},{"id":"https://openalex.org/keywords/endurance-exercise","display_name":"endurance exercise","score":0.5699999928474426},{"id":"https://openalex.org/keywords/cardiovascular-risk-prediction","display_name":"cardiovascular risk prediction","score":0.6320000290870667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5243097543716431},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4759647250175476},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2509291172027588}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:umu-36221","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36221","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:207981039","doi":null,"is_oa":false,"landing_page_url":"http://umu.diva-portal.org/smash/get/diva2:352934/FULLTEXT01","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:umu-36221","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36221","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":144,"referenced_works":["https://openalex.org/W88735253","https://openalex.org/W101847764","https://openalex.org/W140387039","https://openalex.org/W150173255","https://openalex.org/W177064649","https://openalex.org/W202019503","https://openalex.org/W1242386148","https://openalex.org/W1443802491","https://openalex.org/W1552103637","https://openalex.org/W1568390176","https://openalex.org/W1629966220","https://openalex.org/W1812416290","https://openalex.org/W1817200870","https://openalex.org/W1893661163","https://openalex.org/W1901234763","https://openalex.org/W1909056334","https://openalex.org/W1951334717","https://openalex.org/W1964513167","https://openalex.org/W1964943353","https://openalex.org/W1965174204","https://openalex.org/W1966675928","https://openalex.org/W1968295892","https://openalex.org/W1971985756","https://openalex.org/W1974638703","https://openalex.org/W1977261901","https://openalex.org/W1982982006","https://openalex.org/W1986899572","https://openalex.org/W1990223762","https://openalex.org/W1990506334","https://openalex.org/W1992569328","https://openalex.org/W1993029034","https://openalex.org/W1993506680","https://openalex.org/W1996866382","https://openalex.org/W2001953371","https://openalex.org/W2002343382","https://openalex.org/W2003361780","https://openalex.org/W2005349948","https://openalex.org/W2008928218","https://openalex.org/W2014892421","https://openalex.org/W2018135697","https://openalex.org/W2019995128","https://openalex.org/W2023647145","https://openalex.org/W2024886564","https://openalex.org/W2025001402","https://openalex.org/W2028936188","https://openalex.org/W2029608013","https://openalex.org/W2036070208","https://openalex.org/W2039486346","https://openalex.org/W2043957646","https://openalex.org/W2046117118","https://openalex.org/W2046446693","https://openalex.org/W2050167744","https://openalex.org/W2052205324","https://openalex.org/W2053609205","https://openalex.org/W2058591384","https://openalex.org/W2059652342","https://openalex.org/W2061060421","https://openalex.org/W2061511405","https://openalex.org/W2062371885","https://openalex.org/W2063226454","https://openalex.org/W2065699955","https://openalex.org/W2066641505","https://openalex.org/W2066963386","https://openalex.org/W2072005929","https://openalex.org/W2072656254","https://openalex.org/W2073229291","https://openalex.org/W2075125837","https://openalex.org/W2080208126","https://openalex.org/W2081615427","https://openalex.org/W2084292199","https://openalex.org/W2086081611","https://openalex.org/W2089940123","https://openalex.org/W2092336097","https://openalex.org/W2094649779","https://openalex.org/W2097796010","https://openalex.org/W2100419955","https://openalex.org/W2100990638","https://openalex.org/W2101636105","https://openalex.org/W2102036115","https://openalex.org/W2103076184","https://openalex.org/W2103340465","https://openalex.org/W2104618850","https://openalex.org/W2106036991","https://openalex.org/W2110642473","https://openalex.org/W2112857693","https://openalex.org/W2113987248","https://openalex.org/W2114280375","https://openalex.org/W2115966352","https://openalex.org/W2116884033","https://openalex.org/W2117121624","https://openalex.org/W2117287919","https://openalex.org/W2119210523","https://openalex.org/W2119316150","https://openalex.org/W2119363292","https://openalex.org/W2120795994","https://openalex.org/W2121893515","https://openalex.org/W2122073769","https://openalex.org/W2123470976","https://openalex.org/W2123566103","https://openalex.org/W2124312719","https://openalex.org/W2125921569","https://openalex.org/W2127101722","https://openalex.org/W2127486028","https://openalex.org/W2127486207","https://openalex.org/W2129465958","https://openalex.org/W2129551299","https://openalex.org/W2129761019","https://openalex.org/W2134293572","https://openalex.org/W2135392289","https://openalex.org/W2135479614","https://openalex.org/W2136641821","https://openalex.org/W2136961309","https://openalex.org/W2137570167","https://openalex.org/W2138185074","https://openalex.org/W2138195191","https://openalex.org/W2138595885","https://openalex.org/W2139660685","https://openalex.org/W2141285840","https://openalex.org/W2142179136","https://openalex.org/W2143648826","https://openalex.org/W2144871493","https://openalex.org/W2146917818","https://openalex.org/W2146980963","https://openalex.org/W2148824946","https://openalex.org/W2150807996","https://openalex.org/W2154604035","https://openalex.org/W2155121555","https://openalex.org/W2156722540","https://openalex.org/W2156744146","https://openalex.org/W2157622195","https://openalex.org/W2162483087","https://openalex.org/W2163092745","https://openalex.org/W2163451548","https://openalex.org/W2163853417","https://openalex.org/W2169537897","https://openalex.org/W2171748766","https://openalex.org/W2316376271","https://openalex.org/W2317055961","https://openalex.org/W2324841714","https://openalex.org/W2329993286","https://openalex.org/W2331697328","https://openalex.org/W2401758208","https://openalex.org/W2411826498","https://openalex.org/W3022401702"],"related_works":["https://openalex.org/W2647886943","https://openalex.org/W7016631514","https://openalex.org/W3147721753","https://openalex.org/W7099823877","https://openalex.org/W2768859025","https://openalex.org/W2347151078","https://openalex.org/W2127038926","https://openalex.org/W2042401120","https://openalex.org/W2112329799","https://openalex.org/W2037349803"],"abstract_inverted_index":{"Despite":[0],"major":[1],"advances":[2],"in":[3,23,45,50,164,214,256],"the":[4,10,19,26,38,46,64,68,143,172,218,356,393,402,418,444],"treatment":[5],"and":[6,32,59,88,98,142,174,246,259,353,396,441],"prevention":[7],"of":[8,21,36,61,78,148,181,212,231,296,330,355,383,420,422],"atherosclerosis":[9],"last":[11],"several":[12,133],"decades,":[13],"cardiovascular":[14,39,51,126,138],"disease":[15,40,52,139],"still":[16],"accounts":[17],"for":[18,91,125,137,325,351,430],"majority":[20],"deaths":[22],"Sweden.":[24],"With":[25],"population":[27],"getting":[28],"older,":[29],"more":[30,96],"obese":[31,183],"with":[33,55,132,185,239,253,266,280,293,300,304,312,345,405,417],"rising":[34],"numbers":[35],"diabetics,":[37],"burden":[41],"may":[42],"increase":[43],"further":[44],"future.":[47],"The":[48,221,284,411],"focus":[49],"has":[53,74],"shifted":[54],"time":[56],"from":[57],"calcification":[58],"narrowing":[60],"arteries":[62],"to":[63,190,217,274,317,366,375,446],"biological":[65],"processes":[66],"within":[67],"atherosclerotic":[69],"plaque.":[70],"C-reactive":[71,128],"protein":[72,129],"(CRP)":[73],"emerged":[75],"as":[76,93],"one":[77,201],"many":[79],"proteins":[80],"that":[81,112,401],"reflect":[82],"a":[83,122,153,162,179,191,200,205,234,373,381,435],"low":[84,166],"grade":[85],"systemic":[86],"inflammation":[87,320,447],"is":[89,95,114,130,380,408,415],"suitable":[90],"analysis":[92],"it":[94,371],"stable":[97],"easily":[99],"measured":[100],"than":[101],"most":[102],"other":[103,134],"inflammatory":[104,118],"markers.":[105],"Several":[106],"large":[107],"prospective":[108],"studies":[109],"have":[110],"shown":[111],"CRP":[113,168,213,250,277,285,326,352,368,379,403],"not":[115,227,409],"only":[116],"an":[117],"marker,":[119],"but":[120,226,298,370,386,443],"even":[121,348],"predictive":[123],"marker":[124,382],"disease.":[127,283],"associated":[131,252,279,292,344,416],"risk":[135,419],"factors":[136],"including":[140],"obesity":[141],"metabolic":[144,357],"syndrome.":[145,358],"Our":[146,432],"study":[147,180,238,308],"twenty":[149],"healthy":[150],"men":[151],"during":[152],"two":[154],"week":[155],"endurance":[156],"cross":[157],"country":[158],"skiing":[159],"tour":[160,173],"demonstrated":[161],"decline":[163],"already":[165],"baseline":[167],"levels":[169,211,295],"immediately":[170],"after":[171,228,333,349,425,428],"six":[175],"weeks":[176],"later.":[177],"In":[178,233,336,359],"200":[182],"individuals":[184],"impaired":[186],"glucose":[187],"tolerance":[188],"randomised":[189],"counselling":[192],"session":[193],"at":[194,204,224],"their":[195],"health":[196],"care":[197],"centre":[198],"or":[199],"month":[202],"stay":[203],"wellness":[206,219],"centre,":[207],"we":[208],"found":[209,265],"decreased":[210],"subjects":[215],"admitted":[216],"centre.":[220],"effect":[222],"remained":[223],"one,":[225],"three":[229],"years":[230],"follow-up.":[232],"prospective,":[235],"nested,":[236],"case-referent":[237],"308":[240],"ischemic":[241,254,271,301,384,406],"strokes,":[242],"61":[243],"intracerebral":[244,267,305],"haemorrhages":[245],"735":[247],"matched":[248],"referents,":[249],"was":[251,264,278,291,315,343],"stroke":[255,272,302,398,407],"both":[257],"uni-":[258],"multivariate":[260,337],"analyses.":[261],"No":[262],"association":[263],"haemorrhages.":[268],"When":[269],"classifying":[270],"according":[273],"TOAST":[275],"criteria,":[276],"small":[281],"vessel":[282],"1444":[286],"(CC/CT":[287],"vs.":[288],"TT)":[289],"polymorphism":[290,395],"plasma":[294],"CRP,":[297],"neither":[299],"nor":[303],"haemorrhage.":[306],"A":[307],"on":[309],"129":[310],"patients":[311],"atrial":[313,331,423,439],"fibrillation":[314,332,424,440],"used":[316,365],"evaluate":[318],"whether":[319],"sensitive":[321],"fibrinolytic":[322,412],"variables":[323],"adjusted":[324],"could":[327],"predict":[328],"recurrence":[329,421],"electrical":[334,426],"cardioversion.":[335],"iv":[338],"models,":[339],"lower":[340],"PAI-1":[341],"mass":[342],"sinus":[346],"rhythm":[347],"adjusting":[350],"markers":[354],"conclusion,":[360],"lifestyle":[361],"intervention":[362],"can":[363],"be":[364],"reduce":[367],"levels,":[369],"remains":[372,448],"challenge":[374],"maintain":[376],"this":[377],"effect.":[378],"stroke,":[385],"there":[387],"are":[388],"no":[389],"significant":[390],"associations":[391],"between":[392,438],"CRP1444":[394],"any":[397],"subtype,":[399],"suggesting":[400],"relationship":[404],"causal.":[410],"variable,":[413],"PAI-1,":[414,442],"cardioversion":[427],"adjustment":[429],"CRP.":[431],"findings":[433],"suggest":[434],"pathophysiological":[436],"link":[437],"relation":[445],"unclear.":[449]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}