{"id":"https://openalex.org/W2079413595","doi":"https://doi.org/10.1016/0090-6980(75)90057-x","title":"The synthesis of prostaglandin analogs containing hydroxycyclohexenyl rings","display_name":"The synthesis of prostaglandin analogs containing hydroxycyclohexenyl rings","publication_year":1975,"publication_date":"1975-04-01","ids":{"openalex":"https://openalex.org/W2079413595","doi":"https://doi.org/10.1016/0090-6980(75)90057-x","mag":"2079413595","pmid":"https://pubmed.ncbi.nlm.nih.gov/1153807"},"language":"en","primary_location":{"id":"doi:10.1016/0090-6980(75)90057-x","doi":"https://doi.org/10.1016/0090-6980(75)90057-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0090-6980(75)90057-x","pdf_url":null,"source":{"id":"https://openalex.org/S161580142","display_name":"Prostaglandins","issn_l":"0090-6980","issn":["0090-6980","1878-416X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prostaglandins","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109135326","display_name":"Henry C. Arndt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Henry C. Arndt","raw_affiliation_strings":["Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085795604","display_name":"William G. Biddlecom","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William G. Biddlecom","raw_affiliation_strings":["Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090216531","display_name":"Harold C.E. Kluender","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Harold C. Kluender","raw_affiliation_strings":["Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019817364","display_name":"George P. Peruzzotti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George P. Peruzzotti","raw_affiliation_strings":["Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068018530","display_name":"Warren D. Woessner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Warren D. Woessner","raw_affiliation_strings":["Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Miles Laboratories, 3301 Kinsman Boulevard, Madison, Wisconsin, USA 53704","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4615,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.81130952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"4","first_page":"521","last_page":"525"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.2912999987602234,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.2912999987602234,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12228","display_name":"Coordination Chemistry and Organometallics","score":0.18709999322891235,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.15440000593662262,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostaglandin-analogs","display_name":"prostaglandin analogues","score":0.9990000128746033},{"id":"https://openalex.org/keywords/total-synthesis","display_name":"total synthesis","score":0.5320000052452087}],"concepts":[{"id":"https://openalex.org/C2777903533","wikidata":"https://www.wikidata.org/wiki/Q2292678","display_name":"Cyclopentenone","level":2,"score":0.9524220824241638},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.8273487091064453},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.8259228467941284},{"id":"https://openalex.org/C2780664492","wikidata":"https://www.wikidata.org/wiki/Q209717","display_name":"Prostaglandin","level":2,"score":0.7129806280136108},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6302863359451294},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5694947242736816},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3861865997314453},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17559781670570374},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.04987528920173645},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003511","descriptor_name":"Cyclohexanols","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D003517","descriptor_name":"Cyclopentanes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007082","descriptor_name":"Ileum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009119","descriptor_name":"Muscle Contraction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011453","descriptor_name":"Prostaglandins","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D011453","descriptor_name":"Prostaglandins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0090-6980(75)90057-x","doi":"https://doi.org/10.1016/0090-6980(75)90057-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0090-6980(75)90057-x","pdf_url":null,"source":{"id":"https://openalex.org/S161580142","display_name":"Prostaglandins","issn_l":"0090-6980","issn":["0090-6980","1878-416X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prostaglandins","raw_type":"journal-article"},{"id":"pmid:1153807","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1153807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prostaglandins","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W1970640306","https://openalex.org/W1992292853","https://openalex.org/W2025899967","https://openalex.org/W2031167143","https://openalex.org/W2951513199"],"related_works":["https://openalex.org/W2069364232","https://openalex.org/W2025694863","https://openalex.org/W2953152249","https://openalex.org/W2952760651","https://openalex.org/W2937576647","https://openalex.org/W2008146673","https://openalex.org/W6996744313","https://openalex.org/W2047223576","https://openalex.org/W4251603164","https://openalex.org/W1994720771"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}