{"id":"https://openalex.org/W2079095976","doi":"https://doi.org/10.1371/journal.pone.0028552","title":"The Discovery of Putative Urine Markers for the Specific Detection of Prostate Tumor by Integrative Mining of Public Genomic Profiles","display_name":"The Discovery of Putative Urine Markers for the Specific Detection of Prostate Tumor by Integrative Mining of Public Genomic Profiles","publication_year":2011,"publication_date":"2011-12-16","ids":{"openalex":"https://openalex.org/W2079095976","doi":"https://doi.org/10.1371/journal.pone.0028552","mag":"2079095976","pmid":"https://pubmed.ncbi.nlm.nih.gov/22194848","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3241627"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0028552","doi":"https://doi.org/10.1371/journal.pone.0028552","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0028552","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0028552&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0028552&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100337242","display_name":"Min Chen","orcid":"https://orcid.org/0000-0002-7572-0761","observed_orcids":["https://orcid.org/0000-0002-7572-0761"]},"institutions":[{"id":"https://openalex.org/I27357992","display_name":"Dalian University of Technology","ror":"https://ror.org/023hj5876","country_code":"CN","type":"education","lineage":["https://openalex.org/I27357992"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Chen","raw_affiliation_strings":["Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, People's Republic of China","School of Software, Dalian University of Technology, Dalian, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, People's Republic of China","institution_ids":["https://openalex.org/I27357992"]},{"raw_affiliation_string":"School of Software, Dalian University of Technology, Dalian, People's Republic of China","institution_ids":["https://openalex.org/I27357992"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kai Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kai Wang","raw_affiliation_strings":["Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100425247","display_name":"Liang Zhang","orcid":"https://orcid.org/0000-0002-8514-5123","observed_orcids":["https://orcid.org/0000-0002-8514-5123"]},"institutions":[{"id":"https://openalex.org/I27357992","display_name":"Dalian University of Technology","ror":"https://ror.org/023hj5876","country_code":"CN","type":"education","lineage":["https://openalex.org/I27357992"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Zhang","raw_affiliation_strings":["Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, People's Republic of China","School of Software, Dalian University of Technology, Dalian, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, People's Republic of China","institution_ids":["https://openalex.org/I27357992"]},{"raw_affiliation_string":"School of Software, Dalian University of Technology, Dalian, People's Republic of China","institution_ids":["https://openalex.org/I27357992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100354298","display_name":"Cheng Li","orcid":"https://orcid.org/0000-0003-4366-6139","observed_orcids":["https://orcid.org/0000-0003-4366-6139"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Cheng Li","raw_affiliation_strings":["Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077997329","display_name":"Yongliang Yang","orcid":"https://orcid.org/0000-0003-0449-0599","observed_orcids":["https://orcid.org/0000-0003-0449-0599"]},"institutions":[{"id":"https://openalex.org/I27357992","display_name":"Dalian University of Technology","ror":"https://ror.org/023hj5876","country_code":"CN","type":"education","lineage":["https://openalex.org/I27357992"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yongliang Yang","raw_affiliation_strings":["Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Medicine, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, People's Republic of China","institution_ids":["https://openalex.org/I27357992"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5077997329","https://openalex.org/A5100354298"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I27357992","https://openalex.org/I4210117453"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":0.908,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.72276037,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"6","issue":"12","first_page":"e28552","last_page":"e28552"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.7314000129699707,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.7314000129699707,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.18140000104904175,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.996999979019165},{"id":"https://openalex.org/keywords/urinary-biomarkers","display_name":"urinary biomarkers","score":0.9070000052452087},{"id":"https://openalex.org/keywords/non-invasive-cancer-detection","display_name":"non-invasive cancer detection","score":0.8769999742507935},{"id":"https://openalex.org/keywords/urine-protein","display_name":"urinary protein","score":0.6190000176429749},{"id":"https://openalex.org/keywords/bladder-cancer","display_name":"bladder cancer","score":0.6140000224113464},{"id":"https://openalex.org/keywords/kidney-cancer","display_name":"kidney cancer","score":0.996999979019165},{"id":"https://openalex.org/keywords/exosomes","display_name":"exosomes","score":0.8130000233650208},{"id":"https://openalex.org/keywords/protein-protein-interaction-network","display_name":"protein-protein interaction network","score":0.8880000114440918},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7979999780654907},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6100000143051147}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7275669574737549},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5032865405082703},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.4704030454158783},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46783390641212463},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.4659577012062073},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.46062105894088745},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.4526873826980591},{"id":"https://openalex.org/C2781261824","wikidata":"https://www.wikidata.org/wiki/Q903634","display_name":"Exosome","level":5,"score":0.4397720396518707},{"id":"https://openalex.org/C20518536","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicles","level":4,"score":0.4299372136592865},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.39196470379829407},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.2259272038936615},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15337347984313965},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10291817784309387},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0729227066040039}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025941","descriptor_name":"Protein Interaction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pone.0028552","doi":"https://doi.org/10.1371/journal.pone.0028552","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0028552","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0028552&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3241627","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3241627","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:22194848","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22194848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.799.1273","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.799.1273","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/73/3a/pone.0028552.PMC3241627.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:6a64d44afb814a15b9f3a32d71896ddf","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6a64d44afb814a15b9f3a32d71896ddf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 6, Iss 12, p e28552 (2011)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0028552","doi":"https://doi.org/10.1371/journal.pone.0028552","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0028552","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0028552&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5547979785","display_name":"dChip:Analysis and Visualization of Oligonucleotide Expression and SNP Arrays","funder_award_id":"R01GM077122","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2079095976.pdf","grobid_xml":"https://content.openalex.org/works/W2079095976.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1875112053","https://openalex.org/W1964066987","https://openalex.org/W1968904113","https://openalex.org/W1978586903","https://openalex.org/W1985213868","https://openalex.org/W2003528295","https://openalex.org/W2005345468","https://openalex.org/W2039055941","https://openalex.org/W2039365712","https://openalex.org/W2040034810","https://openalex.org/W2047360869","https://openalex.org/W2082668371","https://openalex.org/W2099423097","https://openalex.org/W2108710051","https://openalex.org/W2109694492","https://openalex.org/W2116423958","https://openalex.org/W2125989214","https://openalex.org/W2136364250","https://openalex.org/W2137531873","https://openalex.org/W2141885858","https://openalex.org/W2143129697","https://openalex.org/W2152667145","https://openalex.org/W2155142785","https://openalex.org/W2155680682","https://openalex.org/W2157795344","https://openalex.org/W2162218188","https://openalex.org/W2167933222","https://openalex.org/W2168898378","https://openalex.org/W2171437346","https://openalex.org/W4210623056","https://openalex.org/W4238452917","https://openalex.org/W4294107304"],"related_works":["https://openalex.org/W7017654108","https://openalex.org/W3121697723","https://openalex.org/W4362541418","https://openalex.org/W2004741537","https://openalex.org/W4205560432","https://openalex.org/W1980593265","https://openalex.org/W3032086697","https://openalex.org/W2615062025","https://openalex.org/W2004674740","https://openalex.org/W2745706068"],"abstract_inverted_index":{"Urine":[0],"has":[1],"emerged":[2],"as":[3,132,163,179],"an":[4],"attractive":[5],"biofluid":[6],"for":[7,25,43,62,95,208],"the":[8,26,44,115,146,160,185],"noninvasive":[9],"detection":[10],"of":[11,31,36,46,105,124,148,189,205,211],"prostate":[12,63],"cancer":[13,67,107,110],"(PCa).":[14],"There":[15],"is":[16,193],"a":[17,52,121,168,175,203,209],"strong":[18],"imperative":[19],"to":[20,57,183,195],"discover":[21,196],"candidate":[22,59],"urinary":[23,92,128],"markers":[24,61,93,178,182,200],"clinical":[27],"diagnosis":[28],"and":[29,54,75,108,118,152,173,187,197],"prognosis":[30],"PCa.":[32,190],"The":[33],"rising":[34],"flood":[35],"various":[37],"omics":[38],"profiles":[39,69],"presents":[40],"immense":[41],"opportunities":[42],"identification":[45],"prospective":[47],"biomarkers.":[48],"Here":[49],"we":[50,138,165],"present":[51,201],"simple":[53],"efficient":[55],"strategy":[56],"derive":[58],"urine":[60,177],"tumor":[64,149],"by":[65,154],"mining":[66],"genomic":[68],"from":[70,81],"public":[71],"databases.":[72],"Prostate,":[73],"bladder":[74,106],"kidney":[76,109],"are":[77,111],"three":[78],"major":[79],"tissues":[80],"which":[82],"cellular":[83],"matters":[84],"could":[85],"be":[86,101],"released":[87],"into":[88],"urine.":[89],"To":[90],"identify":[91],"specific":[94],"PCa,":[96],"upregulated":[97],"entities":[98,126,142,162],"that":[99],"might":[100],"shed":[102],"in":[103,202],"exosomes":[104],"first":[112],"excluded.":[113],"Through":[114],"ontology-based":[116],"filtering":[117],"further":[119],"assessment,":[120],"reduced":[122],"list":[123],"19":[125],"encoding":[127],"proteins":[129],"was":[130],"derived":[131],"putative":[133],"PCa":[134],"markers.":[135],"Among":[136],"them,":[137],"have":[139,166],"found":[140],"10":[141,161],"closely":[143],"associated":[144],"with":[145],"process":[147],"cell":[150],"growth":[151],"development":[153],"pathway":[155],"enrichment":[156],"analysis.":[157],"Further,":[158],"using":[159],"seeds,":[164],"constructed":[167],"protein-protein":[169],"interaction":[170],"(PPI)":[171],"subnetwork":[172],"suggested":[174],"few":[176],"preferred":[180],"prognostic":[181],"monitor":[184],"invasion":[186],"progression":[188],"Our":[191],"approach":[192],"amenable":[194],"prioritize":[198],"potential":[199],"variety":[204],"body":[206],"fluids":[207],"spectrum":[210],"human":[212],"diseases.":[213]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}