{"id":"https://openalex.org/W2079091484","doi":"https://doi.org/10.1111/j.1749-6632.1997.tb48446.x","title":"Neuregulins as Potential Neuroprotective Agents","display_name":"Neuregulins as Potential Neuroprotective Agents","publication_year":1997,"publication_date":"1997-10-01","ids":{"openalex":"https://openalex.org/W2079091484","doi":"https://doi.org/10.1111/j.1749-6632.1997.tb48446.x","mag":"2079091484","pmid":"https://pubmed.ncbi.nlm.nih.gov/9370000"},"language":"en","primary_location":{"id":"doi:10.1111/j.1749-6632.1997.tb48446.x","doi":"https://doi.org/10.1111/j.1749-6632.1997.tb48446.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1997.tb48446.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043924261","display_name":"Mark A. Marchionni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"MARK A. MARCHIONNI","raw_affiliation_strings":["Cambridge NeuroScience, Inc., Massachusetts 01239, USA. mark_marchionni@cambneuro.com","Cambridge NeuroScience, Inc. One Kendall Square Cambridge, Massachusetts 01239"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cambridge NeuroScience, Inc., Massachusetts 01239, USA. mark_marchionni@cambneuro.com","institution_ids":[]},{"raw_affiliation_string":"Cambridge NeuroScience, Inc. One Kendall Square Cambridge, Massachusetts 01239","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006907732","display_name":"Judith B. Grinspan","orcid":"https://orcid.org/0000-0003-0940-5314","observed_orcids":["https://orcid.org/0000-0003-0940-5314"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JUDITH B. GRINSPAN","raw_affiliation_strings":["Division of Neurological Research Children's Hospital of Philadelphia Philadelphia, Pennsylvania 19104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neurological Research Children's Hospital of Philadelphia Philadelphia, Pennsylvania 19104","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046673359","display_name":"Peter Canoll","orcid":"https://orcid.org/0000-0002-7001-0226","observed_orcids":["https://orcid.org/0000-0002-7001-0226"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"PETER D. CANOLL","raw_affiliation_strings":["Department of Cell Biology, New York University Medical School, New York, New York 10016"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, New York University Medical School, New York, New York 10016","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019219160","display_name":"Nagesh K. Mahanthappa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"NAGESH K. MAHANTHAPPA","raw_affiliation_strings":["Cambridge NeuroScience, Inc. One Kendall Square Cambridge, Massachusetts 01239"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cambridge NeuroScience, Inc. One Kendall Square Cambridge, Massachusetts 01239","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062858244","display_name":"James L. Salzer","orcid":"https://orcid.org/0000-0001-9126-7197","observed_orcids":["https://orcid.org/0000-0001-9126-7197"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JAMES L. SALZER","raw_affiliation_strings":["Department of Cell Biology, New York University Medical School, New York, New York 10016"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, New York University Medical School, New York, New York 10016","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010248548","display_name":"Steven S. Scherer","orcid":"https://orcid.org/0000-0002-3900-2367","observed_orcids":["https://orcid.org/0000-0002-3900-2367"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"STEVEN S. SCHERER","raw_affiliation_strings":["Department of Neurology University of Pennsylvania Medical Center Philadelphia, Pennsylvania 19104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology University of Pennsylvania Medical Center Philadelphia, Pennsylvania 19104","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5043924261"],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":0.1144,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.11547344,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"825","issue":"1","first_page":"348","last_page":"365"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.8500999808311462,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.8500999808311462,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.06499999761581421,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.014600000344216824,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuregulin","display_name":"neuregulin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.9919999837875366},{"id":"https://openalex.org/keywords/neuroprotective-agents","display_name":"neuroprotective agents","score":0.7860000133514404},{"id":"https://openalex.org/keywords/brain-injury","display_name":"brain injury","score":0.4169999957084656},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.7823606133460999},{"id":"https://openalex.org/C185323287","wikidata":"https://www.wikidata.org/wiki/Q59252204","display_name":"Neuregulin","level":3,"score":0.7151170969009399},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4570044279098511},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2674064636230469},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.1928899586200714},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.16332966089248657},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09491074085235596}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009414","descriptor_name":"Nerve Growth Factors","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009457","descriptor_name":"Neuroglia","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009457","descriptor_name":"Neuroglia","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009836","descriptor_name":"Oligodendroglia","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009836","descriptor_name":"Oligodendroglia","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012583","descriptor_name":"Schwann Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012583","descriptor_name":"Schwann Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1749-6632.1997.tb48446.x","doi":"https://doi.org/10.1111/j.1749-6632.1997.tb48446.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1749-6632.1997.tb48446.x","pdf_url":null,"source":{"id":"https://openalex.org/S8802318","display_name":"Annals of the New York Academy of Sciences","issn_l":"0077-8923","issn":["0077-8923","1749-6632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:9370000","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9370000","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the New York Academy of Sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1560013316","https://openalex.org/W1604121661","https://openalex.org/W1972744392","https://openalex.org/W1973188134","https://openalex.org/W1977243716","https://openalex.org/W1978338248","https://openalex.org/W1980141913","https://openalex.org/W1982210988","https://openalex.org/W1983185480","https://openalex.org/W1983473899","https://openalex.org/W1987657791","https://openalex.org/W1990654868","https://openalex.org/W1994452959","https://openalex.org/W1997914540","https://openalex.org/W2004813091","https://openalex.org/W2005769115","https://openalex.org/W2007309258","https://openalex.org/W2011856091","https://openalex.org/W2016010426","https://openalex.org/W2016405898","https://openalex.org/W2016761620","https://openalex.org/W2018280232","https://openalex.org/W2033836165","https://openalex.org/W2040397739","https://openalex.org/W2042295629","https://openalex.org/W2044833342","https://openalex.org/W2057158750","https://openalex.org/W2058058541","https://openalex.org/W2076682664","https://openalex.org/W2080399383","https://openalex.org/W2081560586","https://openalex.org/W2082026841","https://openalex.org/W2083140708","https://openalex.org/W2084224225","https://openalex.org/W2088591814","https://openalex.org/W2094895636","https://openalex.org/W2110301830","https://openalex.org/W2110795584","https://openalex.org/W2111129548","https://openalex.org/W2115940913","https://openalex.org/W2128133606","https://openalex.org/W2130274176","https://openalex.org/W2151127067","https://openalex.org/W2158330548","https://openalex.org/W2159134891","https://openalex.org/W2165232209","https://openalex.org/W2185470342","https://openalex.org/W2592861607"],"related_works":["https://openalex.org/W617799994","https://openalex.org/W2335430061","https://openalex.org/W1610851390","https://openalex.org/W1984558692","https://openalex.org/W1802137959","https://openalex.org/W1985310722","https://openalex.org/W2020943583","https://openalex.org/W2738976726","https://openalex.org/W2126735914","https://openalex.org/W2070347611"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}