{"id":"https://openalex.org/W2078617837","doi":"https://doi.org/10.1016/s0022-3476(78)80317-5","title":"Excretion of iron in response to deferoxamine in sickle cell anemia","display_name":"Excretion of iron in response to deferoxamine in sickle cell anemia","publication_year":1978,"publication_date":"1978-04-01","ids":{"openalex":"https://openalex.org/W2078617837","doi":"https://doi.org/10.1016/s0022-3476(78)80317-5","mag":"2078617837","pmid":"https://pubmed.ncbi.nlm.nih.gov/633013"},"language":"en","primary_location":{"id":"doi:10.1016/s0022-3476(78)80317-5","doi":"https://doi.org/10.1016/s0022-3476(78)80317-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3476(78)80317-5","pdf_url":null,"source":{"id":"https://openalex.org/S3774022","display_name":"The Journal of Pediatrics","issn_l":"0022-3476","issn":["0022-3476","1085-8695","1097-6833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101889067","display_name":"Alan R. Cohen","orcid":"https://orcid.org/0000-0002-9506-6541","observed_orcids":["https://orcid.org/0000-0002-9506-6541"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alan Cohen","raw_affiliation_strings":["Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pa. USA","The Children's Hospital of Philadelphia, Philadelphia, Pa. USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pa. USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Children's Hospital of Philadelphia, Philadelphia, Pa. USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075699991","display_name":"Elias Schwartz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elias Schwartz","raw_affiliation_strings":["Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pa. USA","The Children's Hospital of Philadelphia, Philadelphia, Pa. USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pa. USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Children's Hospital of Philadelphia, Philadelphia, Pa. USA","institution_ids":["https://openalex.org/I1335321130"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101889067"],"corresponding_institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"],"apc_list":{"value":4570,"currency":"USD","value_usd":4570},"apc_paid":null,"fwci":2.7905,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.91294227,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"92","issue":"4","first_page":"659","last_page":"662"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.013299999758601189,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sickle-cell-disease","display_name":"sickle cell disease","score":0.9739999771118164},{"id":"https://openalex.org/keywords/deferoxamine","display_name":"deferoxamine","score":0.9779999852180481},{"id":"https://openalex.org/keywords/iron-chelation","display_name":"iron chelation","score":0.9269999861717224},{"id":"https://openalex.org/keywords/urinary-iron-excretion","display_name":"urinary iron excretion","score":0.9810000061988831},{"id":"https://openalex.org/keywords/iron-overload","display_name":"iron overload","score":0.7720000147819519},{"id":"https://openalex.org/keywords/blood-transfusion","display_name":"blood transfusion","score":0.7540000081062317},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.843999981880188},{"id":"https://openalex.org/keywords/pediatric-patients","display_name":"pediatric patients","score":0.5400000214576721},{"id":"https://openalex.org/keywords/iron-stores","display_name":"iron stores","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C2776672577","wikidata":"https://www.wikidata.org/wiki/Q419618","display_name":"Deferoxamine","level":2,"score":0.9266941547393799},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9156628847122192},{"id":"https://openalex.org/C2778620579","wikidata":"https://www.wikidata.org/wiki/Q185034","display_name":"Sickle cell anemia","level":3,"score":0.6493625640869141},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.6157399415969849},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.5523121356964111},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34379470348358154},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.11632618308067322}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001803","descriptor_name":"Blood Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003676","descriptor_name":"Deferoxamine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003676","descriptor_name":"Deferoxamine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007263","descriptor_name":"Infusions, Parenteral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D017707","descriptor_name":"Erythrocyte Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0022-3476(78)80317-5","doi":"https://doi.org/10.1016/s0022-3476(78)80317-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3476(78)80317-5","pdf_url":null,"source":{"id":"https://openalex.org/S3774022","display_name":"The Journal of Pediatrics","issn_l":"0022-3476","issn":["0022-3476","1085-8695","1097-6833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pediatrics","raw_type":"journal-article"},{"id":"pmid:633013","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/633013","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of pediatrics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1484754873","https://openalex.org/W1511101472","https://openalex.org/W1577505215","https://openalex.org/W1952356754","https://openalex.org/W1982629808","https://openalex.org/W1991632536","https://openalex.org/W2000448122","https://openalex.org/W2010035240","https://openalex.org/W2011692631","https://openalex.org/W2014521487","https://openalex.org/W2016055426","https://openalex.org/W2037749245","https://openalex.org/W2040543160","https://openalex.org/W2051597612","https://openalex.org/W2077281091","https://openalex.org/W2088689065","https://openalex.org/W2198428752","https://openalex.org/W2328653859","https://openalex.org/W2404692851","https://openalex.org/W2437037440","https://openalex.org/W4247917048"],"related_works":["https://openalex.org/W2006045225","https://openalex.org/W75313515","https://openalex.org/W251003681","https://openalex.org/W2036534494","https://openalex.org/W1978254214","https://openalex.org/W2018780838","https://openalex.org/W4397044172","https://openalex.org/W2378154290","https://openalex.org/W190357846","https://openalex.org/W7098744794"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}