{"id":"https://openalex.org/W2078281979","doi":"https://doi.org/10.1016/0014-5793(91)80103-a","title":"Regulation of the catalytic activity and oligomeric composition of enzymes in reversed micelles of surfactants in organic solvents","display_name":"Regulation of the catalytic activity and oligomeric composition of enzymes in reversed micelles of surfactants in organic solvents","publication_year":1991,"publication_date":"1991-01-28","ids":{"openalex":"https://openalex.org/W2078281979","doi":"https://doi.org/10.1016/0014-5793(91)80103-a","mag":"2078281979","pmid":"https://pubmed.ncbi.nlm.nih.gov/1991503"},"language":"en","primary_location":{"id":"doi:10.1016/0014-5793(91)80103-a","doi":"https://doi.org/10.1016/0014-5793(91)80103-a","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0014-5793(91)80103-a","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2891%2980103-A","source":{"id":"https://openalex.org/S104830714","display_name":"FEBS Letters","issn_l":"0014-5793","issn":["0014-5793","1873-3468"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2891%2980103-A","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060362637","display_name":"Alexander V. Kabanov","orcid":"https://orcid.org/0000-0002-3665-946X","observed_orcids":["https://orcid.org/0000-0002-3665-946X"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexander V. Kabanov","raw_affiliation_strings":["Department of Chemical Enzymology, Moscow State University, USSR","Department of Chemical Enzymology, Moscow State University, Moscow, USSR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Enzymology, Moscow State University, USSR","institution_ids":["https://openalex.org/I19880235"]},{"raw_affiliation_string":"Department of Chemical Enzymology, Moscow State University, Moscow, USSR","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039340847","display_name":"Sergei N. Nametkin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Sergey N. Nametkin","raw_affiliation_strings":["Department of Chemical Enzymology, Moscow State University, Moscow, USSR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Enzymology, Moscow State University, Moscow, USSR","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032833836","display_name":"Natalia L. Klyachko","orcid":"https://orcid.org/0000-0002-9357-8236","observed_orcids":["https://orcid.org/0000-0002-9357-8236"]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Nataliya L. Klyachko","raw_affiliation_strings":["Department of Chemical Enzymology, Moscow State University, Moscow, USSR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Enzymology, Moscow State University, Moscow, USSR","institution_ids":["https://openalex.org/I19880235"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111857225","display_name":"Andrey V. Levashov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Andrey V. Levashov","raw_affiliation_strings":["Department of Chemical Enzymology, Moscow State University, Moscow, USSR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Enzymology, Moscow State University, Moscow, USSR","institution_ids":["https://openalex.org/I19880235"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5039340847"],"corresponding_institution_ids":["https://openalex.org/I19880235"],"apc_list":{"value":3980,"currency":"USD","value_usd":3980},"apc_paid":null,"fwci":2.4762,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.90161376,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"278","issue":"2","first_page":"143","last_page":"146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.11320000141859055,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11617","display_name":"Enzyme Production and Characterization","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.8320000171661377},{"id":"https://openalex.org/keywords/reverse-micelles","display_name":"reverse micelles","score":0.9509999752044678},{"id":"https://openalex.org/keywords/sodium-bis-2-ethylhexyl-sulfosuccinate","display_name":"sodium bis(2-ethylhexyl) sulfosuccinate","score":0.9800000190734863},{"id":"https://openalex.org/keywords/aerosol-optical-depth","display_name":"aerosol optical depth","score":0.5619999766349792},{"id":"https://openalex.org/keywords/octane","display_name":"octane","score":0.8930000066757202},{"id":"https://openalex.org/keywords/alpha-chymotrypsin","display_name":"alpha-chymotrypsin","score":0.9350000023841858},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.996999979019165},{"id":"https://openalex.org/keywords/degree-of-hydration","display_name":"degree of hydration","score":0.7350000143051147},{"id":"https://openalex.org/keywords/enzyme-dimerization","display_name":"enzyme dimerization","score":0.7990000247955322},{"id":"https://openalex.org/keywords/enzyme-quaternary-structure","display_name":"enzyme quaternary structure","score":0.5260000228881836}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7967234253883362},{"id":"https://openalex.org/C2779546866","wikidata":"https://www.wikidata.org/wiki/Q531306","display_name":"Dimer","level":2,"score":0.7198552489280701},{"id":"https://openalex.org/C166940927","wikidata":"https://www.wikidata.org/wiki/Q178827","display_name":"Monomer","level":3,"score":0.6483948230743408},{"id":"https://openalex.org/C11268172","wikidata":"https://www.wikidata.org/wiki/Q421110","display_name":"Micelle","level":3,"score":0.6362643837928772},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.5942252278327942},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.530908465385437},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.5212367177009583},{"id":"https://openalex.org/C207374878","wikidata":"https://www.wikidata.org/wiki/Q3274587","display_name":"Hydrodynamic radius","level":4,"score":0.46519434452056885},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.4243174195289612},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.385567843914032},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.15953311324119568},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000469","descriptor_name":"Alkaline Phosphatase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002918","descriptor_name":"Chymotrypsin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008823","descriptor_name":"Micelles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008823","descriptor_name":"Micelles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008823","descriptor_name":"Micelles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009795","descriptor_name":"Octanes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009795","descriptor_name":"Octanes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009795","descriptor_name":"Octanes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046911","descriptor_name":"Macromolecular Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046911","descriptor_name":"Macromolecular Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046911","descriptor_name":"Macromolecular Substances","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0014-5793(91)80103-a","doi":"https://doi.org/10.1016/0014-5793(91)80103-a","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0014-5793(91)80103-a","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2891%2980103-A","source":{"id":"https://openalex.org/S104830714","display_name":"FEBS Letters","issn_l":"0014-5793","issn":["0014-5793","1873-3468"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS Letters","raw_type":"journal-article"},{"id":"pmid:1991503","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1991503","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS letters","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/0014-5793(91)80103-a","doi":"https://doi.org/10.1016/0014-5793(91)80103-a","is_oa":true,"landing_page_url":"https://doi.org/10.1016/0014-5793(91)80103-a","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2891%2980103-A","source":{"id":"https://openalex.org/S104830714","display_name":"FEBS Letters","issn_l":"0014-5793","issn":["0014-5793","1873-3468"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS Letters","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6","score":0.6299999952316284}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2078281979.pdf","grobid_xml":"https://content.openalex.org/works/W2078281979.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W31935675","https://openalex.org/W112033475","https://openalex.org/W1492793778","https://openalex.org/W1507938174","https://openalex.org/W1686849190","https://openalex.org/W1986486768","https://openalex.org/W1993964963","https://openalex.org/W2001409631","https://openalex.org/W2023347251","https://openalex.org/W2051758098","https://openalex.org/W2058475414"],"related_works":["https://openalex.org/W2953251415","https://openalex.org/W1975231683","https://openalex.org/W2092889823","https://openalex.org/W2126853599","https://openalex.org/W894066805","https://openalex.org/W4253249727","https://openalex.org/W1972220625","https://openalex.org/W2127915608","https://openalex.org/W2407990031","https://openalex.org/W2949498492"],"abstract_inverted_index":{"The":[0,43,75,95,170],"phenomenon":[1],"of":[2,4,8,18,21,45,64,68,91,97,111,128,135,158,166,172,176,195,213,222,247,251],"regulation":[3],"the":[5,16,46,51,58,61,65,72,89,92,103,109,125,129,133,156,159,162,173,219,241],"catalytic":[6,48,77,174],"activity":[7,49,78,175],"enzymes":[9],"via":[10],"changing":[11],"their":[12],"oligomeric":[13,105,220,249],"composition":[14,221],"in":[15,25,108,218],"system":[17],"reversed":[19],"micelles":[20],"sodium":[22],"bis(2-ethylhexyl)sulfosuccinate":[23],"(AOT)":[24],"octane":[26],"was":[27],"studied":[28],"using":[29],"alpha-chymotrypsin":[30],"(CT)":[31],"from":[32,39,227],"bovine":[33],"brain":[34],"and":[35],"alkaline":[36],"phosphatase":[37],"(AP)":[38],"calf":[40],"intestinal":[41],"mucosa.":[42],"dependences":[44],"enzyme":[47,93,104],"on":[50,178],"AOT":[52],"hydration":[53],"degree":[54],"(Wo":[55,199,205,229,236],"=":[56,118,149,200,206],"[H2O]/[AOT]),":[57],"parameter":[59],"determining":[60],"radius":[62,126,157],"(rc)":[63],"inner":[66],"cavity":[67],"micelles,":[69],"usually":[70],"represent":[71],"bell-shaped":[73],"curves.":[74],"maximal":[76],"is":[79,86,114,122,145,153,191],"observed":[80,115,146,188,242],"at":[81,116,147],"such":[82],"Wo":[83,117,148,179,214],"when":[84,120,151,189],"rc":[85,121,152,190],"equal":[87,123,154,192],"to":[88,124,155,193,233,245],"size":[90],"molecule.":[94],"position":[96],"this":[98,113,144],"maximum":[99],"strictly":[100],"correlates":[101],"with":[102,183],"composition.":[106],"Thus,":[107],"case":[110,134],"CT":[112,130,142,168],"12":[119],"(rp)":[127],"globule.":[131],"In":[132],"artificially":[136],"produced":[137],"conjugate":[138],"containing":[139],"six":[140,167],"cross-linked":[141],"molecules,":[143],"43":[150],"sphere":[160],"surrounding":[161],"absolute":[163],"octahedron":[164],"composed":[165],"globules.":[169],"dependence":[171],"AP":[177,197,203,223],"represents":[180],"a":[181,216],"curve":[182],"two":[184],"maxima":[185,243],"that":[186,211],"are":[187],"rp":[194],"either":[196],"monomer":[198],"17)":[201],"or":[202],"dimer":[204],"25).":[207],"Ultracentrifugation":[208],"experiments":[209],"revealed":[210],"variation":[212],"causes":[215],"change":[217],"-":[224],"its":[225],"transition":[226],"monomeric":[228],"less":[230],"than":[231,238],"20)":[232],"dimeric":[234],"form":[235],"greater":[237],"20).":[239],"Hence,":[240],"correspond":[244],"functioning":[246],"different":[248],"forms":[250],"AP.":[252]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}