{"id":"https://openalex.org/W2078033465","doi":"https://doi.org/10.1111/1574-6968.12330","title":"Discrepancies among three laboratory methods forClostridium difficiledetection and a proposal for their optimal use","display_name":"Discrepancies among three laboratory methods forClostridium difficiledetection and a proposal for their optimal use","publication_year":2013,"publication_date":"2013-11-18","ids":{"openalex":"https://openalex.org/W2078033465","doi":"https://doi.org/10.1111/1574-6968.12330","mag":"2078033465","pmid":"https://pubmed.ncbi.nlm.nih.gov/24236508"},"language":"en","primary_location":{"id":"doi:10.1111/1574-6968.12330","doi":"https://doi.org/10.1111/1574-6968.12330","is_oa":false,"landing_page_url":"https://doi.org/10.1111/1574-6968.12330","pdf_url":null,"source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103331793","display_name":"Alexandre Amorim Monteiro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134363262","display_name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre","ror":"https://ror.org/00x0nkm13","country_code":"BR","type":"education","lineage":["https://openalex.org/I134363262"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alexandre A. Monteiro","raw_affiliation_strings":["Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I134363262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038994409","display_name":"Renata Neto Pires","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134363262","display_name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre","ror":"https://ror.org/00x0nkm13","country_code":"BR","type":"education","lineage":["https://openalex.org/I134363262"]},{"id":"https://openalex.org/I2800505568","display_name":"Santa Casa Hospital","ror":"https://ror.org/01by1qv45","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I2800505568"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Renata N. Pires","raw_affiliation_strings":["Santa Casa de Miseric\u00f3rdia de Porto Alegre; Porto Alegre Brazil","Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santa Casa de Miseric\u00f3rdia de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I2800505568"]},{"raw_affiliation_string":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I134363262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013665334","display_name":"Ludmila Fiorenzano Baethgen","orcid":"https://orcid.org/0000-0002-4871-8877","observed_orcids":["https://orcid.org/0000-0002-4871-8877"]},"institutions":[{"id":"https://openalex.org/I134363262","display_name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre","ror":"https://ror.org/00x0nkm13","country_code":"BR","type":"education","lineage":["https://openalex.org/I134363262"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ludmila F. Baethgen","raw_affiliation_strings":["Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I134363262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009637166","display_name":"L\u00ed\u00adlian Carla Carneiro","orcid":"https://orcid.org/0000-0003-4067-1506","observed_orcids":["https://orcid.org/0000-0003-4067-1506"]},"institutions":[{"id":"https://openalex.org/I134363262","display_name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre","ror":"https://ror.org/00x0nkm13","country_code":"BR","type":"education","lineage":["https://openalex.org/I134363262"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Lilian C. Carneiro","raw_affiliation_strings":["Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I134363262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084992808","display_name":"Rejane Giacomelli Tavares","orcid":"https://orcid.org/0000-0002-9806-1893","observed_orcids":["https://orcid.org/0000-0002-9806-1893"]},"institutions":[{"id":"https://openalex.org/I145689991","display_name":"Universidade Feevale","ror":"https://ror.org/05gefd119","country_code":"BR","type":"education","lineage":["https://openalex.org/I145689991"]},{"id":"https://openalex.org/I169248161","display_name":"Universidade Federal de Pelotas","ror":"https://ror.org/05msy9z54","country_code":"BR","type":"education","lineage":["https://openalex.org/I169248161"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rejane G. Tavares","raw_affiliation_strings":["Universidade Federal De Pelotas, Pelotas, Brazil","Universidade Feevale, Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal De Pelotas, Pelotas, Brazil","institution_ids":["https://openalex.org/I169248161"]},{"raw_affiliation_string":"Universidade Feevale, Porto Alegre, Brazil","institution_ids":["https://openalex.org/I145689991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027351937","display_name":"Juliana Caier\u00e3o","orcid":"https://orcid.org/0000-0002-8776-8447","observed_orcids":["https://orcid.org/0000-0002-8776-8447"]},"institutions":[{"id":"https://openalex.org/I134363262","display_name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre","ror":"https://ror.org/00x0nkm13","country_code":"BR","type":"education","lineage":["https://openalex.org/I134363262"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Juliana Caier\u00e3o","raw_affiliation_strings":["Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I134363262"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020852034","display_name":"Steven Park","orcid":"https://orcid.org/0000-0002-6757-1559","observed_orcids":["https://orcid.org/0000-0002-6757-1559"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Park","raw_affiliation_strings":["Public Health Research Institute, New Jersey Medical School, New Jersey, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Public Health Research Institute, New Jersey Medical School, New Jersey, NJ, USA","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005383633","display_name":"David S. Perlin","orcid":"https://orcid.org/0000-0002-9503-3184","observed_orcids":["https://orcid.org/0000-0002-9503-3184","https://orcid.org/0000-0002-1268-5524"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David S. Perlin","raw_affiliation_strings":["Public Health Research Institute, New Jersey Medical School, New Jersey, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Public Health Research Institute, New Jersey Medical School, New Jersey, NJ, USA","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035564899","display_name":"\u00c9dison Moraes Rodrigues Filho","orcid":"https://orcid.org/0000-0002-9750-3653","observed_orcids":["https://orcid.org/0000-0002-9750-3653"]},"institutions":[{"id":"https://openalex.org/I2800505568","display_name":"Santa Casa Hospital","ror":"https://ror.org/01by1qv45","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I2800505568"]},{"id":"https://openalex.org/I4210131915","display_name":"Grupo Hospitalar Concei\u00e7\u00e3o","ror":"https://ror.org/0387j8q89","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210131915"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Edison M. Rodrigues Filho","raw_affiliation_strings":["Grupo Hospitalar Concei\u00e7\u00e3o; Porto Alegre Brazil","Santa Casa de Miseric\u00f3rdia de Porto Alegre; Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo Hospitalar Concei\u00e7\u00e3o; Porto Alegre Brazil","institution_ids":["https://openalex.org/I4210131915"]},{"raw_affiliation_string":"Santa Casa de Miseric\u00f3rdia de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I2800505568"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081472175","display_name":"Alessandro Comar\u00fa Pasqualotto","orcid":"https://orcid.org/0000-0002-6782-5395","observed_orcids":["https://orcid.org/0000-0002-6782-5395"]},"institutions":[{"id":"https://openalex.org/I134363262","display_name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre","ror":"https://ror.org/00x0nkm13","country_code":"BR","type":"education","lineage":["https://openalex.org/I134363262"]},{"id":"https://openalex.org/I2800505568","display_name":"Santa Casa Hospital","ror":"https://ror.org/01by1qv45","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I2800505568"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Alessandro C. Pasqualotto","raw_affiliation_strings":["Santa Casa de Miseric\u00f3rdia de Porto Alegre; Porto Alegre Brazil","Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santa Casa de Miseric\u00f3rdia de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I2800505568"]},{"raw_affiliation_string":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre; Porto Alegre Brazil","institution_ids":["https://openalex.org/I134363262"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5081472175"],"corresponding_institution_ids":["https://openalex.org/I134363262","https://openalex.org/I2800505568"],"apc_list":{"value":2500,"currency":"GBP","value_usd":3297},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.13475539,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"350","issue":"2","first_page":"133","last_page":"137"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12499","display_name":"Diphtheria, Corynebacterium, and Tetanus","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clostridioides-difficile","display_name":"Clostridium difficile","score":1.0},{"id":"https://openalex.org/keywords/clostridium-difficile-associated-diarrhea","display_name":"Clostridium difficile-associated diarrhea","score":0.925000011920929},{"id":"https://openalex.org/keywords/nosocomial-diarrhea","display_name":"nosocomial diarrhea","score":0.7990000247955322},{"id":"https://openalex.org/keywords/toxin-b-gene","display_name":"toxin B gene","score":0.5979999899864197},{"id":"https://openalex.org/keywords/real-time-pcr","display_name":"real-time PCR","score":0.8360000252723694},{"id":"https://openalex.org/keywords/enzyme-immunoassay","display_name":"enzyme immunoassay","score":0.890999972820282},{"id":"https://openalex.org/keywords/diagnostic-test-comparison","display_name":"diagnostic test comparison","score":0.7080000042915344},{"id":"https://openalex.org/keywords/asymptomatic-carriers","display_name":"asymptomatic carriers","score":0.6970000267028809},{"id":"https://openalex.org/keywords/c-difficile-colonization","display_name":"C. difficile colonization","score":0.8109999895095825},{"id":"https://openalex.org/keywords/screening","display_name":"screening","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C2994496256","wikidata":"https://www.wikidata.org/wiki/Q27031090","display_name":"Clostridium difficile","level":3,"score":0.919399082660675},{"id":"https://openalex.org/C137916694","wikidata":"https://www.wikidata.org/wiki/Q1549382","display_name":"Asymptomatic carrier","level":3,"score":0.71925288438797},{"id":"https://openalex.org/C134193097","wikidata":"https://www.wikidata.org/wiki/Q5135489","display_name":"Clostridium difficile toxin B","level":5,"score":0.6660319566726685},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.6564038395881653},{"id":"https://openalex.org/C97505648","wikidata":"https://www.wikidata.org/wiki/Q5135488","display_name":"Clostridium difficile toxin A","level":4,"score":0.5988495349884033},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5453907251358032},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5200297832489014},{"id":"https://openalex.org/C3019428505","wikidata":"https://www.wikidata.org/wiki/Q574905","display_name":"C difficile","level":4,"score":0.4761659801006317},{"id":"https://openalex.org/C2776607351","wikidata":"https://www.wikidata.org/wiki/Q592153","display_name":"Clostridiaceae","level":3,"score":0.43182235956192017},{"id":"https://openalex.org/C2777367657","wikidata":"https://www.wikidata.org/wiki/Q184651","display_name":"Toxin","level":2,"score":0.4201943278312683},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35650748014450073},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3068374991416931},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.128483384847641}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001938","descriptor_name":"Brazil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004761","descriptor_name":"Enterocolitis, Pseudomembranous","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D004761","descriptor_name":"Enterocolitis, Pseudomembranous","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015373","descriptor_name":"Bacterial Typing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D015373","descriptor_name":"Bacterial Typing Techniques","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D016360","descriptor_name":"Clostridioides difficile","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016360","descriptor_name":"Clostridioides difficile","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D060888","descriptor_name":"Real-Time Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/1574-6968.12330","doi":"https://doi.org/10.1111/1574-6968.12330","is_oa":false,"landing_page_url":"https://doi.org/10.1111/1574-6968.12330","pdf_url":null,"source":{"id":"https://openalex.org/S34954451","display_name":"FEMS Microbiology Letters","issn_l":"0378-1097","issn":["0378-1097","1574-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Microbiology Letters","raw_type":"journal-article"},{"id":"pmid:24236508","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24236508","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS microbiology letters","raw_type":"Letter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1949517763","https://openalex.org/W1964197510","https://openalex.org/W1984608017","https://openalex.org/W2029718679","https://openalex.org/W2040684206","https://openalex.org/W2041676095","https://openalex.org/W2056233231","https://openalex.org/W2082175533","https://openalex.org/W2099040951","https://openalex.org/W2102696728","https://openalex.org/W2102860868","https://openalex.org/W2117992341","https://openalex.org/W2118572948","https://openalex.org/W2127283488","https://openalex.org/W2127608454","https://openalex.org/W2130043670","https://openalex.org/W2143266022","https://openalex.org/W2162742658","https://openalex.org/W2166660180","https://openalex.org/W2167811982","https://openalex.org/W2603390547"],"related_works":["https://openalex.org/W2083533173","https://openalex.org/W1808448760","https://openalex.org/W4232674480","https://openalex.org/W4401872578","https://openalex.org/W2118351170","https://openalex.org/W2103736482","https://openalex.org/W2127608454","https://openalex.org/W1993525241","https://openalex.org/W2147870828","https://openalex.org/W2146570715"],"abstract_inverted_index":{"Clostridium":[0],"difficile":[1,70,132,160],"is":[2],"the":[3,15,35,98,103,140,149],"major":[4],"cause":[5],"of":[6,18,26,37,58,163,172],"nosocomial":[7],"diarrhoea.":[8],"Several":[9],"detection":[10,57],"methods":[11],"are":[12],"available":[13],"for":[14,50,56,130,158],"laboratory":[16,40],"diagnosis":[17],"C.":[19,44,69,86,131,159],"difficile,":[20],"but":[21],"these":[22],"vary":[23],"in":[24,72,102,145],"terms":[25],"sensitivity":[27],"and":[28,61,68,93,121,174],"specificity.":[29],"In":[30],"this":[31],"study,":[32,104,147],"we":[33],"compared":[34],"performance":[36],"three":[38,81],"following":[39],"tests":[41],"to":[42,138,151],"detect":[43],"difficile:":[45],"in-house":[46],"real-time":[47],"PCR":[48,135,173],"aiming":[49],"toxin":[51],"B":[52,62],"gene":[53],"(tcdB),":[54],"EIA":[55,175],"toxins":[59,133],"A":[60,65],"(Premier":[63],"Toxins":[64],"&":[66],"B)":[67],"culture":[71],"selective":[73],"medium":[74],"(bioMerieux).":[75],"Our":[76],"results":[77,120],"were":[78,107,113],"grouped":[79],"into":[80],"categories":[82],"as":[83,109,154],"follows:":[84],"(1)":[85],"difficile-associated":[87],"diarrhoea":[88],"(CDAD);":[89],"(2)":[90],"asymptomatic":[91,114],"carriers;":[92],"(3)":[94],"negative":[95,119],"results.":[96],"Among":[97],"113":[99],"patients":[100],"included":[101],"9":[105,122],"(8.0%)":[106,123],"classified":[108],"CDAD,":[110],"19":[111],"(16.8%)":[112],"carriers,":[115],"76":[116],"(67.2%)":[117],"had":[118],"could":[124],"not":[125],"be":[126,139,152,166],"categorized":[127],"(positive":[128],"test":[129,144],"only).":[134],"was":[136],"found":[137],"most":[141],"sensitive":[142],"diagnostic":[143],"our":[146],"with":[148],"potential":[150],"used":[153],"a":[155,170],"screening":[156],"method":[157],"colonization/CDAD.":[161],"Diagnosis":[162],"CDAD":[164],"would":[165],"better":[167],"performed":[168],"by":[169],"combination":[171],"tests.":[176]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}