{"id":"https://openalex.org/W2077948974","doi":"https://doi.org/10.1021/la101791r","title":"Origin of the Nonadhesive Properties of Fibrinogen Matrices Probed by Force Spectroscopy","display_name":"Origin of the Nonadhesive Properties of Fibrinogen Matrices Probed by Force Spectroscopy","publication_year":2010,"publication_date":"2010-09-30","ids":{"openalex":"https://openalex.org/W2077948974","doi":"https://doi.org/10.1021/la101791r","mag":"2077948974","pmid":"https://pubmed.ncbi.nlm.nih.gov/20883009","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2993253"},"language":"en","primary_location":{"id":"doi:10.1021/la101791r","doi":"https://doi.org/10.1021/la101791r","is_oa":false,"landing_page_url":"https://doi.org/10.1021/la101791r","pdf_url":null,"source":{"id":"https://openalex.org/S75741262","display_name":"Langmuir","issn_l":"0743-7463","issn":["0743-7463","1520-5827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Langmuir","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2993253","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071109680","display_name":"Ivan S. Yermolenko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103030","display_name":"G.V. Kurdyumov Institute for Metal Physics","ror":"https://ror.org/01a1qdv64","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210103030"]},{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["UA","US"],"is_corresponding":false,"raw_author_name":"Ivan S. Yermolenko","raw_affiliation_strings":["Center for Metabolic Biology and School of Life Sciences","Institute for Metal Physics, NAS of Ukraine, Kiev, Ukraine","Center for Metabolic Biology and School of Life Sciences, Arizona State University, Tempe, Arizona 85287, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Metabolic Biology and School of Life Sciences","institution_ids":[]},{"raw_affiliation_string":"Institute for Metal Physics, NAS of Ukraine, Kiev, Ukraine","institution_ids":["https://openalex.org/I4210103030"]},{"raw_affiliation_string":"Center for Metabolic Biology and School of Life Sciences, Arizona State University, Tempe, Arizona 85287, United States","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038084330","display_name":"Alexander Fuhrmann","orcid":"https://orcid.org/0009-0002-9363-6755","observed_orcids":["https://orcid.org/0009-0002-9363-6755"]},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander Fuhrmann","raw_affiliation_strings":["Department of Physics","Arizona State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"Arizona State University","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026161950","display_name":"Sergei Magonov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138285227","display_name":"Agilent Technologies (United States)","ror":"https://ror.org/02tryst02","country_code":"US","type":"company","lineage":["https://openalex.org/I138285227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sergei N. Magonov","raw_affiliation_strings":["Agilent Technologies, Chandler, Arizona 85226, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agilent Technologies, Chandler, Arizona 85226, United States","institution_ids":["https://openalex.org/I138285227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089366225","display_name":"Valeryi K. Lishko","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Valeryi K. Lishko","raw_affiliation_strings":["Center for Metabolic Biology and School of Life Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Metabolic Biology and School of Life Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059148543","display_name":"Stanislav P. Oshkadyerov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149851306","display_name":"National Academy of Sciences of Ukraine","ror":"https://ror.org/00je4t102","country_code":"UA","type":"government","lineage":["https://openalex.org/I149851306"]},{"id":"https://openalex.org/I4210103030","display_name":"G.V. Kurdyumov Institute for Metal Physics","ror":"https://ror.org/01a1qdv64","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210103030"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Stanislav P. Oshkadyerov","raw_affiliation_strings":["Institute for Metal Physics, NAS of Ukraine, Kiev, Ukraine","G.V. Kurdyumov Institute for Metal Physics, National Academy of Sciences of Ukraine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Metal Physics, NAS of Ukraine, Kiev, Ukraine","institution_ids":["https://openalex.org/I4210103030"]},{"raw_affiliation_string":"G.V. Kurdyumov Institute for Metal Physics, National Academy of Sciences of Ukraine","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210103030"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078158932","display_name":"Robert Ros","orcid":"https://orcid.org/0000-0001-9271-4091","observed_orcids":["https://orcid.org/0000-0001-9271-4091"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Robert Ros","raw_affiliation_strings":["Department of Physics","CLAS-NS: Biological Physics, Center for"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"CLAS-NS: Biological Physics, Center for","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042525731","display_name":"Tatiana P. Ugarova","orcid":"https://orcid.org/0000-0003-4449-5140","observed_orcids":["https://orcid.org/0000-0003-4449-5140"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Tatiana P. Ugarova","raw_affiliation_strings":["Center for Metabolic Biology and School of Life Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Metabolic Biology and School of Life Sciences","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5042525731","https://openalex.org/A5078158932"],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.1262,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.87669277,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"26","issue":"22","first_page":"17269","last_page":"17277"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.7544000148773193,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.7544000148773193,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.17110000550746918,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.9330000281333923},{"id":"https://openalex.org/keywords/integrin-mediated-cell-adhesion","display_name":"integrin-mediated adhesion","score":0.921999990940094},{"id":"https://openalex.org/keywords/outside-in-signaling","display_name":"outside-in signaling","score":0.8389999866485596},{"id":"https://openalex.org/keywords/fibrinogen-adsorption","display_name":"fibrinogen adsorption","score":0.7739999890327454},{"id":"https://openalex.org/keywords/adhesion-force","display_name":"adhesion force","score":0.7099999785423279},{"id":"https://openalex.org/keywords/mechanical-compliance","display_name":"mechanical compliance","score":0.6069999933242798},{"id":"https://openalex.org/keywords/cross-linking","display_name":"crosslinking","score":0.9120000004768372},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.675000011920929},{"id":"https://openalex.org/keywords/biomaterials","display_name":"biomaterials","score":0.8930000066757202}],"concepts":[{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.8527252674102783},{"id":"https://openalex.org/C119473381","wikidata":"https://www.wikidata.org/wiki/Q49298","display_name":"Force spectroscopy","level":3,"score":0.8029104471206665},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.644126296043396},{"id":"https://openalex.org/C7070889","wikidata":"https://www.wikidata.org/wiki/Q902488","display_name":"Monolayer","level":2,"score":0.59078449010849},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.5436486601829529},{"id":"https://openalex.org/C68928338","wikidata":"https://www.wikidata.org/wiki/Q131790","display_name":"Adhesive","level":3,"score":0.5272865891456604},{"id":"https://openalex.org/C192157962","wikidata":"https://www.wikidata.org/wiki/Q4087243","display_name":"Bilayer","level":3,"score":0.49816083908081055},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4867818057537079},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.43780988454818726},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.42555394768714905},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.3677635192871094},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3554571270942688},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3228488564491272},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.24566900730133057},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16996899247169495},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12205508351325989},{"id":"https://openalex.org/C2779227376","wikidata":"https://www.wikidata.org/wiki/Q6505497","display_name":"Layer (electronics)","level":2,"score":0.1098928451538086},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.07470071315765381},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000269","descriptor_name":"Adhesives","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000269","descriptor_name":"Adhesives","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005340","descriptor_name":"Fibrinogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005340","descriptor_name":"Fibrinogen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018625","descriptor_name":"Microscopy, Atomic Force","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1021/la101791r","doi":"https://doi.org/10.1021/la101791r","is_oa":false,"landing_page_url":"https://doi.org/10.1021/la101791r","pdf_url":null,"source":{"id":"https://openalex.org/S75741262","display_name":"Langmuir","issn_l":"0743-7463","issn":["0743-7463","1520-5827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Langmuir","raw_type":"journal-article"},{"id":"pmid:20883009","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20883009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Langmuir : the ACS journal of surfaces and colloids","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2217221","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2993253","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2993253","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2993253","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Langmuir","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2217221","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2993253","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000859045","display_name":"The role of beta 2 integrins in macrophage fusion","funder_award_id":"R01HL063199","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1505258801","https://openalex.org/W1507013396","https://openalex.org/W1895289679","https://openalex.org/W1964680129","https://openalex.org/W1983331713","https://openalex.org/W1986611667","https://openalex.org/W1993079150","https://openalex.org/W2002445925","https://openalex.org/W2003649362","https://openalex.org/W2003977686","https://openalex.org/W2009100337","https://openalex.org/W2012809150","https://openalex.org/W2014444592","https://openalex.org/W2015332717","https://openalex.org/W2019014231","https://openalex.org/W2020866997","https://openalex.org/W2022383769","https://openalex.org/W2022908994","https://openalex.org/W2027854020","https://openalex.org/W2029499720","https://openalex.org/W2030076176","https://openalex.org/W2039511397","https://openalex.org/W2042156094","https://openalex.org/W2044023324","https://openalex.org/W2051290691","https://openalex.org/W2064659937","https://openalex.org/W2067581909","https://openalex.org/W2067601493","https://openalex.org/W2075096412","https://openalex.org/W2079069178","https://openalex.org/W2090718182","https://openalex.org/W2097517504","https://openalex.org/W2123122212","https://openalex.org/W2135846300","https://openalex.org/W2136949471","https://openalex.org/W2137963069","https://openalex.org/W2160124075","https://openalex.org/W2409311163","https://openalex.org/W2417508769","https://openalex.org/W2436653369","https://openalex.org/W3117368973","https://openalex.org/W4300560771","https://openalex.org/W4324262994"],"related_works":["https://openalex.org/W2068958822","https://openalex.org/W2980457146","https://openalex.org/W1984021141","https://openalex.org/W151110053","https://openalex.org/W4415224513","https://openalex.org/W2072203052","https://openalex.org/W893572315","https://openalex.org/W7100810103","https://openalex.org/W2070587519","https://openalex.org/W2123122212"],"abstract_inverted_index":{"The":[0,26,51,122,143],"deposition":[1,124],"of":[2,15,28,47,78,87,92,125,132,175,187,211,217,223],"a":[3,12,29,43,93,98,117,136,176,184],"multilayered":[4],"fibrinogen":[5,33,39,48,80,88,133,146,160,179,192,213],"matrix":[6,40],"on":[7],"various":[8],"surfaces":[9],"results":[10,134],"in":[11,22,75,89,101,135,140,197,219,227],"dramatic":[13],"reduction":[14,100],"integrin-mediated":[16],"cell":[17,118],"adhesion":[18,103,141],"and":[19,24,64,110,119,171,190,226],"outside-in":[20],"signaling":[21],"platelets":[23],"leukocytes.":[25],"conversion":[27],"highly":[30],"adhesive,":[31],"low-density":[32],"substrate":[34,112],"to":[35,70],"the":[36,72,76,85,90,102,107,111,120,158,165,169,188,198,201,204,208,220],"nonadhesive":[37,79,212],"high-density":[38],"occurs":[41],"within":[42],"very":[44],"narrow":[45],"range":[46],"coating":[49,130],"concentrations.":[50],"molecular":[52,65,94],"events":[53],"responsible":[54],"for":[55],"this":[56],"transition":[57],"are":[58],"not":[59],"well":[60,114],"understood.":[61],"Herein,":[62],"single-cell":[63],"force":[66,155],"spectroscopy":[67],"were":[68],"used":[69],"determine":[71],"early":[73],"steps":[74],"formation":[77],"substrates.":[81],"We":[82,181],"show":[83],"that":[84,183],"adsorption":[86],"form":[91],"bilayer":[95,147,167],"coincides":[96],"with":[97],"several-fold":[99],"forces":[104],"generated":[105],"between":[106,116,200],"AFM":[108],"tip":[109],"as":[113,115],"substrate.":[121],"subsequent":[123],"new":[126],"layers":[127],"at":[128],"higher":[129],"concentrations":[131],"small":[137],"additional":[138],"decrease":[139],"forces.":[142],"poorly":[144],"adhesive":[145,172,178],"is":[148,157],"more":[149,177],"extensible":[150],"under":[151],"an":[152],"applied":[153],"tensile":[154],"than":[156],"surface-bound":[159],"monolayer.":[161,180],"Following":[162],"chemical":[163],"cross-linking,":[164],"stabilized":[166],"displays":[168],"mechanical":[170,209],"properties":[173,210],"characteristic":[174],"propose":[182],"greater":[185],"compliance":[186],"bi-":[189],"multilayer":[191],"matrices":[193,214],"has":[194],"its":[195],"origin":[196],"interaction":[199],"molecules":[202],"forming":[203],"adjacent":[205],"layers.":[206],"Understanding":[207],"should":[215],"be":[216],"importance":[218],"therapeutic":[221],"control":[222],"pathological":[224],"thrombosis":[225],"biomaterials":[228],"science.":[229]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}