{"id":"https://openalex.org/W2077926432","doi":"https://doi.org/10.1016/s0009-2797(00)00167-8","title":"Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells","display_name":"Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells","publication_year":2000,"publication_date":"2000-07-01","ids":{"openalex":"https://openalex.org/W2077926432","doi":"https://doi.org/10.1016/s0009-2797(00)00167-8","mag":"2077926432","pmid":"https://pubmed.ncbi.nlm.nih.gov/10936227"},"language":"en","primary_location":{"id":"doi:10.1016/s0009-2797(00)00167-8","doi":"https://doi.org/10.1016/s0009-2797(00)00167-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0009-2797(00)00167-8","pdf_url":null,"source":{"id":"https://openalex.org/S34460812","display_name":"Chemico-Biological Interactions","issn_l":"0009-2797","issn":["0009-2797","1872-7786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-Biological Interactions","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028245593","display_name":"Myriam Coulet","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Myriam Coulet","raw_affiliation_strings":["INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille BP3, 31931, Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille BP3, 31931, Toulouse, France","institution_ids":["https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007684374","display_name":"C. Eeckhoutte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Claudine Eeckhoutte","raw_affiliation_strings":["INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France","institution_ids":["https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083370178","display_name":"G. Larrieu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gilberte Larrieu","raw_affiliation_strings":["INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France","institution_ids":["https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112642168","display_name":"Jean\u2010Fran\u00e7ois Sutra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Fran\u00e7ois Sutra","raw_affiliation_strings":["INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France","institution_ids":["https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110223951","display_name":"M. Alvinerie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Michel Alvinerie","raw_affiliation_strings":["INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France","institution_ids":["https://openalex.org/I4210088668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046882477","display_name":"Katherine Mac\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405279210","display_name":"Nestec (Switzerland)","ror":"https://ror.org/014x0er85","country_code":"CH","type":"company","lineage":["https://openalex.org/I4210112383","https://openalex.org/I4405279210"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Katherine Mac\u00e9","raw_affiliation_strings":["Nestec Ltd., Research Centre, PO Box 44, CH-1000 Lausanne 26, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nestec Ltd., Research Centre, PO Box 44, CH-1000 Lausanne 26, Switzerland","institution_ids":["https://openalex.org/I4405279210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110880738","display_name":"Andrea C. Pfeifer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405279210","display_name":"Nestec (Switzerland)","ror":"https://ror.org/014x0er85","country_code":"CH","type":"company","lineage":["https://openalex.org/I4210112383","https://openalex.org/I4405279210"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Andrea Pfeifer","raw_affiliation_strings":["Nestec Ltd., Research Centre, PO Box 44, CH-1000 Lausanne 26, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nestec Ltd., Research Centre, PO Box 44, CH-1000 Lausanne 26, Switzerland","institution_ids":["https://openalex.org/I4405279210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110937344","display_name":"Flavia Zucco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154278","display_name":"Institute of Biomedical Technologies","ror":"https://ror.org/04ehykb85","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210154278","https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Flavia Zucco","raw_affiliation_strings":["Istituto di Tecnologie Biomediche, CNR, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto di Tecnologie Biomediche, CNR, Rome, Italy","institution_ids":["https://openalex.org/I4210154278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108242253","display_name":"Annalaura Paganuzzi Stammati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Anna Laura Stammati","raw_affiliation_strings":["Istituto Superiore di Sanit\u00e0, Laboratorio di Tossicologia Comparata ed Ecotossicologia, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Superiore di Sanit\u00e0, Laboratorio di Tossicologia Comparata ed Ecotossicologia, Rome, Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032779620","display_name":"Isabella De Angelis","orcid":"https://orcid.org/0000-0001-7820-3631","observed_orcids":["https://orcid.org/0000-0001-7820-3631"]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Isabella De Angelis","raw_affiliation_strings":["Istituto Superiore di Sanit\u00e0, Laboratorio di Tossicologia Comparata ed Ecotossicologia, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Superiore di Sanit\u00e0, Laboratorio di Tossicologia Comparata ed Ecotossicologia, Rome, Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049041222","display_name":"Anna Lidia Vignoli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Anna Lidia Vignoli","raw_affiliation_strings":["Istituto Superiore di Sanit\u00e0, Laboratorio di Tossicologia Comparata ed Ecotossicologia, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istituto Superiore di Sanit\u00e0, Laboratorio di Tossicologia Comparata ed Ecotossicologia, Rome, Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035351503","display_name":"Pierre Galtier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Pierre Galtier","raw_affiliation_strings":["INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INRA, Laboratoire de Pharmacologie-Toxicologie, 180 Chemin de Tournefeuille, BP3, 31931 Toulouse, France","institution_ids":["https://openalex.org/I4210088668"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5035351503"],"corresponding_institution_ids":["https://openalex.org/I4210088668"],"apc_list":{"value":3540,"currency":"USD","value_usd":3540},"apc_paid":null,"fwci":1.1974,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.76068999,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"127","issue":"2","first_page":"109","last_page":"124"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.02710000053048134,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thiabendazole","display_name":"thiabendazole","score":1.0},{"id":"https://openalex.org/keywords/cyp1a2","display_name":"CYP1A2","score":0.9290000200271606},{"id":"https://openalex.org/keywords/covalent-protein-binding","display_name":"covalent protein binding","score":0.8730000257492065},{"id":"https://openalex.org/keywords/benzimidazole-fungicides","display_name":"benzimidazole fungicides","score":0.8080000281333923},{"id":"https://openalex.org/keywords/cyp-inducers","display_name":"CYP inducers","score":0.6140000224113464},{"id":"https://openalex.org/keywords/beta-naphthoflavone","display_name":"beta-naphthoflavone","score":0.9309999942779541},{"id":"https://openalex.org/keywords/drug-metabolism","display_name":"drug metabolism","score":0.4659999907016754},{"id":"https://openalex.org/keywords/metabolic-activation","display_name":"metabolic activation","score":0.5669999718666077},{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.5249999761581421},{"id":"https://openalex.org/keywords/human-bronchial-epithelial-cells","display_name":"human bronchial epithelial cells","score":0.7789999842643738}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7199850082397461},{"id":"https://openalex.org/C86745063","wikidata":"https://www.wikidata.org/wiki/Q3737406","display_name":"CYP1A2","level":4,"score":0.703738808631897},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.6828604340553284},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5929014086723328},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.5044475793838501},{"id":"https://openalex.org/C109650736","wikidata":"https://www.wikidata.org/wiki/Q424440","display_name":"CYP3A4","level":4,"score":0.47258174419403076},{"id":"https://openalex.org/C87644729","wikidata":"https://www.wikidata.org/wiki/Q547502","display_name":"Microsome","level":3,"score":0.46573296189308167},{"id":"https://openalex.org/C2781109383","wikidata":"https://www.wikidata.org/wiki/Q898497","display_name":"Hydroxylation","level":3,"score":0.4430118203163147},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3815177083015442}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000969","descriptor_name":"Antinematodal Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000969","descriptor_name":"Antinematodal Agents","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D000969","descriptor_name":"Antinematodal Agents","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001980","descriptor_name":"Bronchi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001980","descriptor_name":"Bronchi","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003114","descriptor_name":"Colony-Forming Units Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004790","descriptor_name":"Enzyme Induction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007408","descriptor_name":"Intestinal Absorption","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013827","descriptor_name":"Thiabendazole","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D013827","descriptor_name":"Thiabendazole","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013827","descriptor_name":"Thiabendazole","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D013827","descriptor_name":"Thiabendazole","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D018938","descriptor_name":"Caco-2 Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018938","descriptor_name":"Caco-2 Cells","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D019388","descriptor_name":"Cytochrome P-450 CYP1A2","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D019388","descriptor_name":"Cytochrome P-450 CYP1A2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0009-2797(00)00167-8","doi":"https://doi.org/10.1016/s0009-2797(00)00167-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0009-2797(00)00167-8","pdf_url":null,"source":{"id":"https://openalex.org/S34460812","display_name":"Chemico-Biological Interactions","issn_l":"0009-2797","issn":["0009-2797","1872-7786"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-Biological Interactions","raw_type":"journal-article"},{"id":"pmid:10936227","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10936227","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemico-biological interactions","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-02689186v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.inrae.fr/hal-02689186","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Chemico-Biological Interactions, 2000, 127, pp.109-124","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W201548973","https://openalex.org/W593158849","https://openalex.org/W1558112674","https://openalex.org/W1562777547","https://openalex.org/W1563004338","https://openalex.org/W1775749144","https://openalex.org/W1904678284","https://openalex.org/W1969094114","https://openalex.org/W1988097121","https://openalex.org/W1993417033","https://openalex.org/W1993962474","https://openalex.org/W1996292375","https://openalex.org/W1997574513","https://openalex.org/W2000328589","https://openalex.org/W2013331166","https://openalex.org/W2014398218","https://openalex.org/W2022287668","https://openalex.org/W2028345719","https://openalex.org/W2029362945","https://openalex.org/W2030064604","https://openalex.org/W2040348660","https://openalex.org/W2050734291","https://openalex.org/W2059059418","https://openalex.org/W2061788598","https://openalex.org/W2063968553","https://openalex.org/W2069164050","https://openalex.org/W2069510665","https://openalex.org/W2091655067","https://openalex.org/W2092908280","https://openalex.org/W2143984053","https://openalex.org/W2152539673","https://openalex.org/W2157357990","https://openalex.org/W2301685103","https://openalex.org/W2305286984","https://openalex.org/W2396875484","https://openalex.org/W2397625180","https://openalex.org/W2409152313","https://openalex.org/W2419612683","https://openalex.org/W4232534952","https://openalex.org/W6633265384"],"related_works":["https://openalex.org/W2061788598","https://openalex.org/W2030064604","https://openalex.org/W2022287668","https://openalex.org/W4414074739","https://openalex.org/W1988097121","https://openalex.org/W2134612478","https://openalex.org/W1970897722","https://openalex.org/W2066640048","https://openalex.org/W2172019735","https://openalex.org/W2161214777"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}