{"id":"https://openalex.org/W2077145482","doi":"https://doi.org/10.1016/j.cell.2013.06.007","title":"Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei","display_name":"Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei","publication_year":2013,"publication_date":"2013-07-01","ids":{"openalex":"https://openalex.org/W2077145482","doi":"https://doi.org/10.1016/j.cell.2013.06.007","mag":"2077145482","pmid":"https://pubmed.ncbi.nlm.nih.gov/23827674","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3749778"},"language":"en","primary_location":{"id":"doi:10.1016/j.cell.2013.06.007","doi":"https://doi.org/10.1016/j.cell.2013.06.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2013.06.007","pdf_url":"http://www.cell.com/article/S0092867413007095/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0092867413007095/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084957989","display_name":"Emily M. Hatch","orcid":"https://orcid.org/0000-0002-3393-4075","observed_orcids":["https://orcid.org/0000-0002-3393-4075"]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily\u00a0M. Hatch","raw_affiliation_strings":["Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067548092","display_name":"Andrew H. Fischer","orcid":"https://orcid.org/0000-0002-5944-4621","observed_orcids":["https://orcid.org/0000-0002-5944-4621"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew\u00a0H. Fischer","raw_affiliation_strings":["Department of Pathology, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Massachusetts Medical School, 55 Lake Avenue, Worcester, MA 01655, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084271294","display_name":"Thomas J. Deerinck","orcid":"https://orcid.org/0000-0002-1696-8409","observed_orcids":["https://orcid.org/0000-0002-1696-8409"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas\u00a0J. Deerinck","raw_affiliation_strings":["Department of Neurosciences, National Center for Microscopy and Imaging Research, and Center for Research in Biological Systems, University of California, San Diego, La Jolla, CA, 92093-0608, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, National Center for Microscopy and Imaging Research, and Center for Research in Biological Systems, University of California, San Diego, La Jolla, CA, 92093-0608, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011761333","display_name":"Martin W. Hetzer","orcid":"https://orcid.org/0000-0002-2111-992X","observed_orcids":["https://orcid.org/0000-0002-2111-992X"]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Martin\u00a0W. Hetzer","raw_affiliation_strings":["Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA","institution_ids":["https://openalex.org/I1307098950"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5011761333"],"corresponding_institution_ids":["https://openalex.org/I1307098950"],"apc_list":{"value":11400,"currency":"USD","value_usd":11400},"apc_paid":null,"fwci":10.4541,"has_fulltext":false,"cited_by_count":728,"citation_normalized_percentile":{"value":0.99150045,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"154","issue":"1","first_page":"47","last_page":"60"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/micronuclei","display_name":"micronuclei","score":0.8500000238418579},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.8050000071525574},{"id":"https://openalex.org/keywords/genomic-instability","display_name":"genomic instability","score":0.8040000200271606},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.9330000281333923},{"id":"https://openalex.org/keywords/chromatin-condensation","display_name":"chromatin condensation","score":0.7879999876022339},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.8539999723434448},{"id":"https://openalex.org/keywords/nuclear-compartmentalization","display_name":"nuclear compartmentalization","score":0.6629999876022339},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9333915710449219},{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.6888695955276489},{"id":"https://openalex.org/C65155139","wikidata":"https://www.wikidata.org/wiki/Q5380912","display_name":"Envelope (radar)","level":3,"score":0.5059320330619812},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3732181489467621},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.36495813727378845},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35761529207229614},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10570040345191956},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.06939181685447693},{"id":"https://openalex.org/C554190296","wikidata":"https://www.wikidata.org/wiki/Q47528","display_name":"Radar","level":2,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002289","descriptor_name":"Carcinoma, Non-Small-Cell Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007399","descriptor_name":"Interphase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009685","descriptor_name":"Nuclear Envelope","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D034882","descriptor_name":"Lamins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042822","descriptor_name":"Genomic Instability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048629","descriptor_name":"Micronuclei, Chromosome-Defective","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.cell.2013.06.007","doi":"https://doi.org/10.1016/j.cell.2013.06.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2013.06.007","pdf_url":"http://www.cell.com/article/S0092867413007095/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},{"id":"pmid:23827674","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23827674","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3749778","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3749778","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cell","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.cell.2013.06.007","doi":"https://doi.org/10.1016/j.cell.2013.06.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cell.2013.06.007","pdf_url":"http://www.cell.com/article/S0092867413007095/pdf","source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1511897599","display_name":"The role of the nucleoporin Nup98 in gene regulation","funder_award_id":"R01GM098749","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3062569857","display_name":"IVEM and Image Analysis Resource","funder_award_id":"P41GM103412","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4742879151","display_name":null,"funder_award_id":"P30CA014118195","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000880274","display_name":"Cancer Center Support Grant (CCSG)","funder_award_id":"P30CA014195","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2077145482.pdf"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1963929154","https://openalex.org/W1967891302","https://openalex.org/W1969665013","https://openalex.org/W1977016073","https://openalex.org/W1978390749","https://openalex.org/W1981835453","https://openalex.org/W1995816679","https://openalex.org/W2001442551","https://openalex.org/W2003556097","https://openalex.org/W2007680864","https://openalex.org/W2026862467","https://openalex.org/W2042107535","https://openalex.org/W2042168939","https://openalex.org/W2045762186","https://openalex.org/W2047741179","https://openalex.org/W2050505892","https://openalex.org/W2050753155","https://openalex.org/W2062739292","https://openalex.org/W2068290381","https://openalex.org/W2070226977","https://openalex.org/W2070582215","https://openalex.org/W2070739953","https://openalex.org/W2073078178","https://openalex.org/W2075547944","https://openalex.org/W2077436902","https://openalex.org/W2083530785","https://openalex.org/W2086624484","https://openalex.org/W2088969742","https://openalex.org/W2095617425","https://openalex.org/W2096262820","https://openalex.org/W2101712721","https://openalex.org/W2102960342","https://openalex.org/W2109948920","https://openalex.org/W2111560040","https://openalex.org/W2112784018","https://openalex.org/W2114610097","https://openalex.org/W2114830509","https://openalex.org/W2117662529","https://openalex.org/W2121410884","https://openalex.org/W2123618943","https://openalex.org/W2131028776","https://openalex.org/W2138825607","https://openalex.org/W2151847364","https://openalex.org/W2158586651","https://openalex.org/W2159925873","https://openalex.org/W2160973386","https://openalex.org/W2167815875","https://openalex.org/W2169016078","https://openalex.org/W2171051669","https://openalex.org/W4238853108","https://openalex.org/W4243158166"],"related_works":["https://openalex.org/W4244568128","https://openalex.org/W4397030629","https://openalex.org/W2952728370","https://openalex.org/W2996013501","https://openalex.org/W4393096118","https://openalex.org/W4413860658","https://openalex.org/W3109417942","https://openalex.org/W1995816679","https://openalex.org/W4391657527","https://openalex.org/W4282946308"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":54},{"year":2025,"cited_by_count":68},{"year":2024,"cited_by_count":69},{"year":2023,"cited_by_count":65},{"year":2022,"cited_by_count":72},{"year":2021,"cited_by_count":75},{"year":2020,"cited_by_count":79},{"year":2019,"cited_by_count":50},{"year":2018,"cited_by_count":64},{"year":2017,"cited_by_count":39},{"year":2016,"cited_by_count":40},{"year":2015,"cited_by_count":29},{"year":2014,"cited_by_count":19},{"year":2013,"cited_by_count":5}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}