{"id":"https://openalex.org/W2076977895","doi":"https://doi.org/10.2217/rme.13.25","title":"Transient Overexpression of Ppar\u03b32 and C/ebp\u03b1 in Mesenchymal Stem Cells Induces Brown Adipose Tissue Formation","display_name":"Transient Overexpression of Ppar\u03b32 and C/ebp\u03b1 in Mesenchymal Stem Cells Induces Brown Adipose Tissue Formation","publication_year":2013,"publication_date":"2013-04-29","ids":{"openalex":"https://openalex.org/W2076977895","doi":"https://doi.org/10.2217/rme.13.25","mag":"2076977895","pmid":"https://pubmed.ncbi.nlm.nih.gov/23627824"},"language":"en","primary_location":{"id":"doi:10.2217/rme.13.25","doi":"https://doi.org/10.2217/rme.13.25","is_oa":false,"landing_page_url":"https://doi.org/10.2217/rme.13.25","pdf_url":null,"source":{"id":"https://openalex.org/S156036346","display_name":"Regenerative Medicine","issn_l":"1746-0751","issn":["1746-0751","1746-076X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Regenerative Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081116926","display_name":"Dmitriy Sheyn","orcid":"https://orcid.org/0000-0002-3333-1485","observed_orcids":["https://orcid.org/0000-0002-3333-1485"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Dmitriy Sheyn","raw_affiliation_strings":["Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]},{"raw_affiliation_string":"Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036741552","display_name":"Gadi Pelled","orcid":"https://orcid.org/0000-0003-3857-5531","observed_orcids":["https://orcid.org/0000-0003-3857-5531"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Gadi Pelled","raw_affiliation_strings":["Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]},{"raw_affiliation_string":"Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085348660","display_name":"Wafa Tawackoli","orcid":"https://orcid.org/0000-0003-3742-8644","observed_orcids":["https://orcid.org/0000-0003-3742-8644"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wafa Tawackoli","raw_affiliation_strings":["Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101456430","display_name":"Susan Su","orcid":"https://orcid.org/0000-0003-0103-7369","observed_orcids":["https://orcid.org/0000-0003-0103-7369"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Su","raw_affiliation_strings":["Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021570609","display_name":"Shiran Ben\u2010David","orcid":"https://orcid.org/0000-0001-9512-7909","observed_orcids":["https://orcid.org/0000-0001-9512-7909"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shiran Ben-David","raw_affiliation_strings":["Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071238164","display_name":"Dan Gazit","orcid":"https://orcid.org/0000-0002-0554-0028","observed_orcids":["https://orcid.org/0000-0002-0554-0028"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Dan Gazit","raw_affiliation_strings":["Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]},{"raw_affiliation_string":"Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078917882","display_name":"Zulma Gazit","orcid":"https://orcid.org/0000-0001-9176-0889","observed_orcids":["https://orcid.org/0000-0001-9176-0889"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I197251160","display_name":"Hebrew University of Jerusalem","ror":"https://ror.org/03qxff017","country_code":"IL","type":"education","lineage":["https://openalex.org/I197251160"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Zulma Gazit","raw_affiliation_strings":["Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Department of Surgery, Regenerative Medicine Institute, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1282927834"]},{"raw_affiliation_string":"Skeletal Biotech Laboratory, Hebrew University-Hadassah, Faculty of Dental Medicine, Jerusalem, Israel","institution_ids":["https://openalex.org/I197251160"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3894,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.80919521,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"8","issue":"3","first_page":"295","last_page":"308"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.92330002784729,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.92330002784729,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.07069999724626541,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brown-adipose-tissue","display_name":"brown adipose tissue","score":0.9390000104904175},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.9940000176429749},{"id":"https://openalex.org/keywords/ppargamma2","display_name":"PPAR\u03b32","score":0.9120000004768372},{"id":"https://openalex.org/keywords/c-ebpalpha","display_name":"C/EBP\u03b1","score":0.9819999933242798},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.7639999985694885},{"id":"https://openalex.org/keywords/thermogenesis","display_name":"thermogenesis","score":0.7009999752044678},{"id":"https://openalex.org/keywords/ucp1","display_name":"UCP1","score":0.8389999866485596},{"id":"https://openalex.org/keywords/bioluminescence-imaging","display_name":"bioluminescence imaging","score":0.7260000109672546},{"id":"https://openalex.org/keywords/ectopic-implantation","display_name":"ectopic implantation","score":0.6940000057220459},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.36399999260902405},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.7983486652374268},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.7905107140541077},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5664153099060059},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5385111570358276},{"id":"https://openalex.org/C2780642333","wikidata":"https://www.wikidata.org/wiki/Q901269","display_name":"Brown adipose tissue","level":3,"score":0.47385385632514954},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3899257779121399},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3730176091194153},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2212631106376648}],"mesh":[{"descriptor_ui":"D000071256","descriptor_name":"Uncoupling Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002001","descriptor_name":"Adipose Tissue, Brown","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005818","descriptor_name":"Genetic Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008163","descriptor_name":"Luminescent Measurements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022763","descriptor_name":"CCAAT-Enhancer-Binding Protein-alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D038081","descriptor_name":"Organogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047495","descriptor_name":"PPAR gamma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050156","descriptor_name":"Adipogenesis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2217/rme.13.25","doi":"https://doi.org/10.2217/rme.13.25","is_oa":false,"landing_page_url":"https://doi.org/10.2217/rme.13.25","pdf_url":null,"source":{"id":"https://openalex.org/S156036346","display_name":"Regenerative Medicine","issn_l":"1746-0751","issn":["1746-0751","1746-076X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Regenerative Medicine","raw_type":"journal-article"},{"id":"pmid:23627824","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23627824","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Regenerative medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W1523142723","https://openalex.org/W1799788806","https://openalex.org/W1973761480","https://openalex.org/W1974058241","https://openalex.org/W1974831291","https://openalex.org/W1977355870","https://openalex.org/W1981525131","https://openalex.org/W1985107218","https://openalex.org/W1986098635","https://openalex.org/W1987417700","https://openalex.org/W2002492903","https://openalex.org/W2005761023","https://openalex.org/W2009508208","https://openalex.org/W2016775082","https://openalex.org/W2017292651","https://openalex.org/W2019640399","https://openalex.org/W2024292392","https://openalex.org/W2026286888","https://openalex.org/W2027903621","https://openalex.org/W2028357148","https://openalex.org/W2028893284","https://openalex.org/W2032109946","https://openalex.org/W2032660293","https://openalex.org/W2033484101","https://openalex.org/W2039395542","https://openalex.org/W2053952731","https://openalex.org/W2062183137","https://openalex.org/W2064356036","https://openalex.org/W2073103789","https://openalex.org/W2073622625","https://openalex.org/W2088394139","https://openalex.org/W2088840362","https://openalex.org/W2089907400","https://openalex.org/W2094993440","https://openalex.org/W2096722301","https://openalex.org/W2098596035","https://openalex.org/W2100221605","https://openalex.org/W2103612137","https://openalex.org/W2104827888","https://openalex.org/W2107752044","https://openalex.org/W2107793453","https://openalex.org/W2115560928","https://openalex.org/W2117361870","https://openalex.org/W2118544754","https://openalex.org/W2120875133","https://openalex.org/W2126068683","https://openalex.org/W2127424952","https://openalex.org/W2130261021","https://openalex.org/W2131231952","https://openalex.org/W2132358997","https://openalex.org/W2135066766","https://openalex.org/W2139534935","https://openalex.org/W2141106456","https://openalex.org/W2145492658","https://openalex.org/W2146817116","https://openalex.org/W2153263291","https://openalex.org/W2158963518","https://openalex.org/W2167569899","https://openalex.org/W2170245391","https://openalex.org/W2172939187","https://openalex.org/W2341034190"],"related_works":["https://openalex.org/W2077348302","https://openalex.org/W2013935086","https://openalex.org/W4413473925","https://openalex.org/W2551512491","https://openalex.org/W1602868054","https://openalex.org/W2169627084","https://openalex.org/W2372262392","https://openalex.org/W2805813610","https://openalex.org/W2034342156","https://openalex.org/W3048761049"],"abstract_inverted_index":{"BACKGROUND:":[0],"Brown":[1],"adipose":[2,37,71,140,162],"tissue":[3,38,122,141,163],"plays":[4],"a":[5,15],"pivotal":[6],"role":[7],"in":[8,19,63,95,98,106,125,144,147,164,167],"mammal":[9],"metabolism":[10],"and":[11,26,43,60,87,97,119,129,137,146,166],"thermogenesis.":[12],"It":[13],"has":[14],"great":[16],"therapeutic":[17],"potential":[18],"several":[20],"metabolic":[21],"disorders":[22],"such":[23],"as":[24],"obesity":[25],"diabetes.":[27],"Mesenchymal":[28],"stem":[29],"cells":[30,92,105,114],"(MSCs)":[31],"are":[32,45],"suitable":[33],"candidates":[34],"for":[35,116],"brown":[36,120,139,161],"formation":[39,69],"de":[40],"novo.":[41],"Ppar\u03b32":[42,59,86],"C/ebp\u03b1":[44,61],"nucleic":[46],"receptors":[47],"known":[48],"to":[49,67,84],"mediate":[50],"adipogenic":[51],"differentiation.":[52],"We":[53,150],"hypothesized":[54],"that":[55,152],"overexpression":[56],"of":[57,70,90,103,155],"the":[58,68,78,104,112,138],"genes":[62],"MSCs":[64,76,159],"would":[65],"lead":[66],"tissue.":[72],"MATERIALS":[73],"&":[74],"METHODS:":[75],"bearing":[77],"Luc":[79,136],"reporter":[80],"gene":[81,153],"were":[82],"transfected":[83],"overexpress":[85],"C/ebp\u03b1.":[88],"Differentiation":[89],"nucleofected":[91],"was":[93,123],"evaluated":[94],"vitro":[96,145,165],"vivo":[99],"following":[100],"ectopic":[101],"implantation":[102],"C3H/HeN":[107],"mice.":[108],"RESULTS:":[109],"After":[110],"implantation,":[111],"engineered":[113],"survived":[115],"5":[117],"weeks":[118],"adipose-like":[121],"observed":[124],"histological":[126],"samples.":[127],"Immunostaining":[128],"bioluminescent":[130],"imaging":[131],"showed":[132],"new":[133],"adipocytes":[134],"expressing":[135],"marker,":[142],"UCP1,":[143],"vivo.":[148,168],"CONCLUSION:":[149],"show":[151],"delivery":[154],"transcription":[156],"factors":[157],"into":[158],"generates":[160]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}