{"id":"https://openalex.org/W2076974534","doi":"https://doi.org/10.1016/j.tiv.2009.12.009","title":"Cell-density-dependent methylmercury susceptibility of cultured human brain microvascular pericytes","display_name":"Cell-density-dependent methylmercury susceptibility of cultured human brain microvascular pericytes","publication_year":2009,"publication_date":"2009-12-18","ids":{"openalex":"https://openalex.org/W2076974534","doi":"https://doi.org/10.1016/j.tiv.2009.12.009","mag":"2076974534","pmid":"https://pubmed.ncbi.nlm.nih.gov/20005941"},"language":"en","primary_location":{"id":"doi:10.1016/j.tiv.2009.12.009","doi":"https://doi.org/10.1016/j.tiv.2009.12.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tiv.2009.12.009","pdf_url":null,"source":{"id":"https://openalex.org/S39580544","display_name":"Toxicology in Vitro","issn_l":"0887-2333","issn":["0887-2333","1879-3177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology in Vitro","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111782165","display_name":"Takashi Hirooka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49155475","display_name":"Hokuriku University","ror":"https://ror.org/04wcpjy25","country_code":"JP","type":"education","lineage":["https://openalex.org/I49155475"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Hirooka","raw_affiliation_strings":["Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3, Kanagawa-machi, Kanazawa 920-1181, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3, Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088550986","display_name":"Yasuyuki Fujiwara","orcid":"https://orcid.org/0000-0003-0028-0658","observed_orcids":["https://orcid.org/0000-0003-0028-0658"]},"institutions":[{"id":"https://openalex.org/I195444995","display_name":"Aichi Gakuin University","ror":"https://ror.org/01rwx7470","country_code":"JP","type":"education","lineage":["https://openalex.org/I195444995"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuyuki Fujiwara","raw_affiliation_strings":["Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya, Aichi 464-8650, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya, Aichi 464-8650, Japan","institution_ids":["https://openalex.org/I195444995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068312886","display_name":"Yuka Minami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49155475","display_name":"Hokuriku University","ror":"https://ror.org/04wcpjy25","country_code":"JP","type":"education","lineage":["https://openalex.org/I49155475"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuka Minami","raw_affiliation_strings":["Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010155058","display_name":"Akihiko Ishii","orcid":"https://orcid.org/0000-0003-4638-1294","observed_orcids":["https://orcid.org/0000-0003-4638-1294"]},"institutions":[{"id":"https://openalex.org/I49155475","display_name":"Hokuriku University","ror":"https://ror.org/04wcpjy25","country_code":"JP","type":"education","lineage":["https://openalex.org/I49155475"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akihiko Ishii","raw_affiliation_strings":["Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078855197","display_name":"Mio Ishigooka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I49155475","display_name":"Hokuriku University","ror":"https://ror.org/04wcpjy25","country_code":"JP","type":"education","lineage":["https://openalex.org/I49155475"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mio Ishigooka","raw_affiliation_strings":["Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004496411","display_name":"Yasuhiro Shinkai","orcid":"https://orcid.org/0000-0003-1772-5342","observed_orcids":["https://orcid.org/0000-0003-1772-5342"]},"institutions":[{"id":"https://openalex.org/I49155475","display_name":"Hokuriku University","ror":"https://ror.org/04wcpjy25","country_code":"JP","type":"education","lineage":["https://openalex.org/I49155475"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuhiro Shinkai","raw_affiliation_strings":["Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3, Kanagawa-machi, Kanazawa 920-1181, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3, Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031356291","display_name":"Chika Yamamoto","orcid":"https://orcid.org/0000-0003-4512-8924","observed_orcids":["https://orcid.org/0000-0003-4512-8924"]},"institutions":[{"id":"https://openalex.org/I49155475","display_name":"Hokuriku University","ror":"https://ror.org/04wcpjy25","country_code":"JP","type":"education","lineage":["https://openalex.org/I49155475"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chika Yamamoto","raw_affiliation_strings":["Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]},{"raw_affiliation_string":"Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077968240","display_name":"Masahiko Satoh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I195444995","display_name":"Aichi Gakuin University","ror":"https://ror.org/01rwx7470","country_code":"JP","type":"education","lineage":["https://openalex.org/I195444995"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiko Satoh","raw_affiliation_strings":["Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya, Aichi 464-8650, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya, Aichi 464-8650, Japan","institution_ids":["https://openalex.org/I195444995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075008238","display_name":"Akira Yasutake","orcid":"https://orcid.org/0000-0003-0686-6860","observed_orcids":["https://orcid.org/0000-0003-0686-6860"]},"institutions":[{"id":"https://openalex.org/I4210140020","display_name":"National Institute for Minamata Disease","ror":"https://ror.org/052rvxk90","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210140020"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Yasutake","raw_affiliation_strings":["National Institute for Minamata Disease, 4058-18 Hama, Minamata City, Kumamoto 867-0008, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute for Minamata Disease, 4058-18 Hama, Minamata City, Kumamoto 867-0008, Japan","institution_ids":["https://openalex.org/I4210140020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062131236","display_name":"Komyo Eto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Komyo Eto","raw_affiliation_strings":["Health and Nursing Facilities for the Aged, Jushindai, Shinwakai, 272 Ikura Kitakata, Tamana City, Kumamoto 865-0041, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health and Nursing Facilities for the Aged, Jushindai, Shinwakai, 272 Ikura Kitakata, Tamana City, Kumamoto 865-0041, Japan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100836061","display_name":"Toshiyuki Kaji","orcid":"https://orcid.org/0000-0002-7393-2656","observed_orcids":["https://orcid.org/0000-0002-7393-2656"]},"institutions":[{"id":"https://openalex.org/I49155475","display_name":"Hokuriku University","ror":"https://ror.org/04wcpjy25","country_code":"JP","type":"education","lineage":["https://openalex.org/I49155475"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Toshiyuki Kaji","raw_affiliation_strings":["Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]},{"raw_affiliation_string":"Organization for Frontier Research in Preventive Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan","institution_ids":["https://openalex.org/I49155475"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100836061"],"corresponding_institution_ids":["https://openalex.org/I49155475"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":1.0821,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.74463656,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"24","issue":"3","first_page":"835","last_page":"841"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.9506999850273132,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.9506999850273132,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.035100001841783524,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methylmercury","display_name":"methylmercury","score":0.972000002861023},{"id":"https://openalex.org/keywords/cell-density","display_name":"cell density","score":0.7459999918937683},{"id":"https://openalex.org/keywords/neurotoxicity","display_name":"neurotoxicity","score":0.7540000081062317},{"id":"https://openalex.org/keywords/vascular-toxicity","display_name":"vascular toxicity","score":0.7699999809265137},{"id":"https://openalex.org/keywords/lat1","display_name":"LAT1","score":0.6200000047683716},{"id":"https://openalex.org/keywords/intracellular-accumulation","display_name":"intracellular accumulation","score":0.75},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.8790000081062317},{"id":"https://openalex.org/keywords/metallothionein","display_name":"metallothionein","score":0.9980000257492065},{"id":"https://openalex.org/keywords/inorganic-mercury","display_name":"inorganic mercury","score":0.6759999990463257},{"id":"https://openalex.org/keywords/cadmium","display_name":"cadmium","score":0.953000009059906},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8450000286102295}],"concepts":[{"id":"https://openalex.org/C2780373914","wikidata":"https://www.wikidata.org/wiki/Q414075","display_name":"Methylmercury","level":3,"score":0.9429926872253418},{"id":"https://openalex.org/C2779491297","wikidata":"https://www.wikidata.org/wiki/Q3338704","display_name":"Neurotoxicity","level":3,"score":0.6404160261154175},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6110751032829285},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.5665521025657654},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.4909398853778839},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.48453253507614136},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.4444340765476227},{"id":"https://openalex.org/C20719415","wikidata":"https://www.wikidata.org/wiki/Q416896","display_name":"Metallothionein","level":3,"score":0.44412681460380554},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.4147205948829651},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.41338419914245605},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35437285900115967},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2512413263320923},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.22068944573402405},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.1552751660346985},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12061119079589844},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06947621703147888},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0680321455001831},{"id":"https://openalex.org/C71572567","wikidata":"https://www.wikidata.org/wiki/Q864231","display_name":"Bioaccumulation","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002196","descriptor_name":"Capillaries","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002196","descriptor_name":"Capillaries","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005721","descriptor_name":"Glutamate-Cysteine Ligase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005978","descriptor_name":"Glutathione","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007770","descriptor_name":"L-Lactate Dehydrogenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008668","descriptor_name":"Metallothionein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008767","descriptor_name":"Methylmercury Compounds","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008767","descriptor_name":"Methylmercury Compounds","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017669","descriptor_name":"Mercury Compounds","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017669","descriptor_name":"Mercury Compounds","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020286","descriptor_name":"Pericytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D026923","descriptor_name":"Amino Acid Transport Systems, Basic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D027283","descriptor_name":"Large Neutral Amino Acid-Transporter 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.tiv.2009.12.009","doi":"https://doi.org/10.1016/j.tiv.2009.12.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tiv.2009.12.009","pdf_url":null,"source":{"id":"https://openalex.org/S39580544","display_name":"Toxicology in Vitro","issn_l":"0887-2333","issn":["0887-2333","1879-3177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology in Vitro","raw_type":"journal-article"},{"id":"pmid:20005941","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20005941","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology in vitro : an international journal published in association with BIBRA","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1595366583","https://openalex.org/W1967714577","https://openalex.org/W1968291093","https://openalex.org/W1982061719","https://openalex.org/W1989953524","https://openalex.org/W1990079644","https://openalex.org/W1993721436","https://openalex.org/W1994026753","https://openalex.org/W2009016920","https://openalex.org/W2009603006","https://openalex.org/W2015541518","https://openalex.org/W2023814887","https://openalex.org/W2040123934","https://openalex.org/W2046441392","https://openalex.org/W2052580459","https://openalex.org/W2054431943","https://openalex.org/W2054444894","https://openalex.org/W2056653854","https://openalex.org/W2074460303","https://openalex.org/W2076047293","https://openalex.org/W2081298113","https://openalex.org/W2083312006","https://openalex.org/W2087607022","https://openalex.org/W2114756450","https://openalex.org/W2115390024","https://openalex.org/W2132661781","https://openalex.org/W2140539172","https://openalex.org/W4235369040"],"related_works":["https://openalex.org/W2083456979","https://openalex.org/W2010339632","https://openalex.org/W4396523958","https://openalex.org/W2025998949","https://openalex.org/W4409013000","https://openalex.org/W2039587780","https://openalex.org/W7213653864","https://openalex.org/W3163946168","https://openalex.org/W2171932008","https://openalex.org/W7146753986"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}