{"id":"https://openalex.org/W2076944010","doi":"https://doi.org/10.1038/80450","title":"Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice","display_name":"Skeletal muscle respiratory uncoupling prevents diet-induced obesity and insulin resistance in mice","publication_year":2000,"publication_date":"2000-10-01","ids":{"openalex":"https://openalex.org/W2076944010","doi":"https://doi.org/10.1038/80450","mag":"2076944010","pmid":"https://pubmed.ncbi.nlm.nih.gov/11017142"},"language":"en","primary_location":{"id":"doi:10.1038/80450","doi":"https://doi.org/10.1038/80450","is_oa":false,"landing_page_url":"https://doi.org/10.1038/80450","pdf_url":null,"source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Bing Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bing Li","raw_affiliation_strings":["Departments of Medicine and Cell Biology & Physiology, Division of Atherosclerosis, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, St. Louis, Missouri 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology, Division of Atherosclerosis, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, St. Louis, Missouri 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111734905","display_name":"Lorraine A. Nolte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lorraine A. Nolte","raw_affiliation_strings":["Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060715270","display_name":"Jeong-Sun Ju","orcid":"https://orcid.org/0000-0001-7276-9941","observed_orcids":["https://orcid.org/0000-0001-7276-9941"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeong-Sun Ju","raw_affiliation_strings":["Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039592281","display_name":"Dong Ho Han","orcid":"https://orcid.org/0000-0002-8411-3736","observed_orcids":["https://orcid.org/0000-0002-8411-3736"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dong Ho Han","raw_affiliation_strings":["Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108376928","display_name":"Trey Coleman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trey Coleman","raw_affiliation_strings":["Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110123538","display_name":"John O. Holloszy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John O. Holloszy","raw_affiliation_strings":["Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063847286","display_name":"Clay F. Semenkovich","orcid":"https://orcid.org/0000-0003-1163-1871","observed_orcids":["https://orcid.org/0000-0003-1163-1871","https://orcid.org/0000-0002-0711-6343"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Clay F. Semenkovich","raw_affiliation_strings":["Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine, Box 8046, 660 South Euclid Avenue,  St. Louis, 63110, Missouri, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Departments of Medicine and Cell Biology & Physiology Division of Atherosclerosis, Division of Geriatrics and Gerontology, Nutrition, and Lipid Research, Center for Cardiovascular Research, Washington University School of Medicine,  St. Louis, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5063847286"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":11.1706,"has_fulltext":false,"cited_by_count":289,"citation_normalized_percentile":{"value":0.99177478,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"6","issue":"10","first_page":"1115","last_page":"1120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.13920000195503235,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondrial-uncoupling","display_name":"mitochondrial uncoupling","score":0.7860000133514404},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.8769999742507935},{"id":"https://openalex.org/keywords/diet-induced-obesity","display_name":"diet-induced obesity","score":0.8349999785423279},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9900000095367432},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9700000286102295},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9079999923706055},{"id":"https://openalex.org/keywords/skeletal-muscle-oxygen-consumption","display_name":"skeletal muscle oxygen consumption","score":0.8629999756813049},{"id":"https://openalex.org/keywords/glucose-tolerance","display_name":"glucose tolerance","score":0.859000027179718},{"id":"https://openalex.org/keywords/glucose-transport","display_name":"glucose transport","score":0.7279999852180481},{"id":"https://openalex.org/keywords/muscle-triglycerides","display_name":"muscle triglycerides","score":0.8669999837875366},{"id":"https://openalex.org/keywords/metabolic-rate","display_name":"metabolic rate","score":0.796999990940094},{"id":"https://openalex.org/keywords/exercise-metabolism","display_name":"exercise metabolism","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8610416650772095},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8564140200614929},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.7956134080886841},{"id":"https://openalex.org/C2779406938","wikidata":"https://www.wikidata.org/wiki/Q24720289","display_name":"Uncoupling protein","level":4,"score":0.6900240778923035},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.6623917818069458},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.527208149433136},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5073992609977722},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4962206482887268},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.4840080440044403},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.44054025411605835},{"id":"https://openalex.org/C141035611","wikidata":"https://www.wikidata.org/wiki/Q5532934","display_name":"Genetically modified mouse","level":4,"score":0.43824511766433716},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4292534291744232},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.38993486762046814},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3184841275215149},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2667490243911743},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.16512557864189148},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11588132381439209},{"id":"https://openalex.org/C2780642333","wikidata":"https://www.wikidata.org/wiki/Q901269","display_name":"Brown adipose tissue","level":3,"score":0.08866769075393677},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.053253114223480225}],"mesh":[{"descriptor_ui":"D000071256","descriptor_name":"Uncoupling Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D014475","descriptor_name":"Uncoupling Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019069","descriptor_name":"Cell Respiration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/80450","doi":"https://doi.org/10.1038/80450","is_oa":false,"landing_page_url":"https://doi.org/10.1038/80450","pdf_url":null,"source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},{"id":"pmid:11017142","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11017142","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3671350849","display_name":null,"funder_award_id":"AG00425","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G45885746","display_name":"INTERMEDIARY METABOLISM AND A NOVEL RNA BINDING PROTEIN","funder_award_id":"R01DK053198","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G933518394","display_name":"ATHEROSCLEROSIS, DIABETES AND LPL","funder_award_id":"R01HL058427","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W180691554","https://openalex.org/W331117150","https://openalex.org/W1435468342","https://openalex.org/W1553937914","https://openalex.org/W1583148430","https://openalex.org/W1905697185","https://openalex.org/W1968024017","https://openalex.org/W1972113685","https://openalex.org/W1974418613","https://openalex.org/W1974680883","https://openalex.org/W1986503787","https://openalex.org/W1987588766","https://openalex.org/W1996810555","https://openalex.org/W2000279901","https://openalex.org/W2021365028","https://openalex.org/W2021760176","https://openalex.org/W2027059985","https://openalex.org/W2037204981","https://openalex.org/W2043498565","https://openalex.org/W2051285216","https://openalex.org/W2055239948","https://openalex.org/W2056293291","https://openalex.org/W2059274438","https://openalex.org/W2062073832","https://openalex.org/W2067768014","https://openalex.org/W2075171810","https://openalex.org/W2079167667","https://openalex.org/W2092505879","https://openalex.org/W2099126367","https://openalex.org/W2102547070","https://openalex.org/W2112821460","https://openalex.org/W2130407178","https://openalex.org/W2136689463","https://openalex.org/W2145242451","https://openalex.org/W2148562280","https://openalex.org/W2151584333","https://openalex.org/W2156172044","https://openalex.org/W2157250831","https://openalex.org/W2167376898","https://openalex.org/W2170826886","https://openalex.org/W2172189555","https://openalex.org/W2182867189","https://openalex.org/W2321598419","https://openalex.org/W3119605303","https://openalex.org/W4300938833"],"related_works":["https://openalex.org/W2031664391","https://openalex.org/W1589517965","https://openalex.org/W4221111646","https://openalex.org/W2325126836","https://openalex.org/W2269129210","https://openalex.org/W2112466242","https://openalex.org/W1975982666","https://openalex.org/W2049783305","https://openalex.org/W2125445685","https://openalex.org/W2361976084"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":16},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":16}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}