{"id":"https://openalex.org/W2076849480","doi":"https://doi.org/10.1016/0022-4731(77)90271-0","title":"The effects of low dose diethylstilbestrol administration in neonatal female rats","display_name":"The effects of low dose diethylstilbestrol administration in neonatal female rats","publication_year":1977,"publication_date":"1977-05-01","ids":{"openalex":"https://openalex.org/W2076849480","doi":"https://doi.org/10.1016/0022-4731(77)90271-0","mag":"2076849480","pmid":"https://pubmed.ncbi.nlm.nih.gov/563955"},"language":"en","primary_location":{"id":"doi:10.1016/0022-4731(77)90271-0","doi":"https://doi.org/10.1016/0022-4731(77)90271-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-4731(77)90271-0","pdf_url":null,"source":{"id":"https://openalex.org/S104308233","display_name":"Journal of Steroid Biochemistry","issn_l":"0022-4731","issn":["0022-4731","1878-2353"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320146","host_organization_name":"Pergamon Press","host_organization_lineage":["https://openalex.org/P4310320146"],"host_organization_lineage_names":["Pergamon Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Steroid Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Mary Slaughter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210088756","display_name":"Royal Victoria Hospital","ror":"https://ror.org/00arwy491","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210088756","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Mary Slaughter","raw_affiliation_strings":["Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada","institution_ids":["https://openalex.org/I4210088756","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029092017","display_name":"Richard Wilen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210088756","display_name":"Royal Victoria Hospital","ror":"https://ror.org/00arwy491","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210088756","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Richard Wilen","raw_affiliation_strings":["Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada","institution_ids":["https://openalex.org/I4210088756","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113769876","display_name":"Kenneth Joseph Ryan","orcid":"https://orcid.org/0000-0002-6547-9273","observed_orcids":["https://orcid.org/0000-0002-6547-9273"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210088756","display_name":"Royal Victoria Hospital","ror":"https://ror.org/00arwy491","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210088756","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Kenneth J. Ryan","raw_affiliation_strings":["Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada","institution_ids":["https://openalex.org/I4210088756","https://openalex.org/I5023651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030184373","display_name":"Frederick Nicholas Naftolin","orcid":"https://orcid.org/0000-0002-9447-6266","observed_orcids":["https://orcid.org/0000-0002-9447-6266"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210088756","display_name":"Royal Victoria Hospital","ror":"https://ror.org/00arwy491","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210088756","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA","US"],"is_corresponding":true,"raw_author_name":"Frederick Naftolin","raw_affiliation_strings":["Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gyneeology and Laboratory of Human Reproduction and Reproductive Biology, Harvard Medical School, Boston, MA, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Obstetrics and Gyneeology, McGill Faculty of Medicine and Royal Victoria Hospital, Montreal, P.Q., Canada","institution_ids":["https://openalex.org/I4210088756","https://openalex.org/I5023651"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5030184373"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210088756","https://openalex.org/I5023651"],"apc_list":null,"apc_paid":null,"fwci":0.688,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.69986987,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"5","first_page":"621","last_page":"623"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.4871000051498413,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.4871000051498413,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.2761000096797943,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.2273000031709671,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diethylstilbestrol","display_name":"diethylstilbestrol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neonatal-rats","display_name":"neonatal rats","score":0.6990000009536743},{"id":"https://openalex.org/keywords/testosterone-propionate","display_name":"testosterone propionate","score":0.7860000133514404},{"id":"https://openalex.org/keywords/estradiol-benzoate","display_name":"estradiol benzoate","score":0.9879999756813049},{"id":"https://openalex.org/keywords/persistent-estrus","display_name":"persistent estrus","score":0.8040000200271606},{"id":"https://openalex.org/keywords/female-sterilization","display_name":"female sterilization","score":0.5770000219345093},{"id":"https://openalex.org/keywords/estrogen-binding-protein","display_name":"estrogen-binding protein","score":0.9210000038146973},{"id":"https://openalex.org/keywords/masculinization","display_name":"masculinization","score":0.6370000243186951}],"concepts":[{"id":"https://openalex.org/C2781397067","wikidata":"https://www.wikidata.org/wiki/Q423989","display_name":"Diethylstilbestrol","level":3,"score":0.9155848026275635},{"id":"https://openalex.org/C2781115071","wikidata":"https://www.wikidata.org/wiki/Q10354588","display_name":"Testosterone propionate","level":4,"score":0.898175835609436},{"id":"https://openalex.org/C1998276","wikidata":"https://www.wikidata.org/wiki/Q388121","display_name":"Estrous cycle","level":2,"score":0.7345948219299316},{"id":"https://openalex.org/C2778506572","wikidata":"https://www.wikidata.org/wiki/Q11450699","display_name":"Estradiol benzoate","level":4,"score":0.7233140468597412},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7023440599441528},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6997858285903931},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.6224989891052246},{"id":"https://openalex.org/C3019458133","wikidata":"https://www.wikidata.org/wiki/Q212317","display_name":"Sesame oil","level":3,"score":0.5480515956878662},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4861433207988739},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.45871642231941223},{"id":"https://openalex.org/C2780014933","wikidata":"https://www.wikidata.org/wiki/Q422956","display_name":"Propionate","level":2,"score":0.41657155752182007},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.37958791851997375},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2940702438354492},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.19518595933914185},{"id":"https://openalex.org/C8264082","wikidata":"https://www.wikidata.org/wiki/Q7113259","display_name":"Ovariectomized rat","level":3,"score":0.10590231418609619},{"id":"https://openalex.org/C144027150","wikidata":"https://www.wikidata.org/wiki/Q48803","display_name":"Horticulture","level":1,"score":0.0},{"id":"https://openalex.org/C2780928516","wikidata":"https://www.wikidata.org/wiki/Q47334","display_name":"Sesamum","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004031","descriptor_name":"Diestrus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004054","descriptor_name":"Diethylstilbestrol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004971","descriptor_name":"Estrus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012741","descriptor_name":"Sexual Maturation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0022-4731(77)90271-0","doi":"https://doi.org/10.1016/0022-4731(77)90271-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0022-4731(77)90271-0","pdf_url":null,"source":{"id":"https://openalex.org/S104308233","display_name":"Journal of Steroid Biochemistry","issn_l":"0022-4731","issn":["0022-4731","1878-2353"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320146","host_organization_name":"Pergamon Press","host_organization_lineage":["https://openalex.org/P4310320146"],"host_organization_lineage_names":["Pergamon Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Steroid Biochemistry","raw_type":"journal-article"},{"id":"pmid:563955","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/563955","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of steroid biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1596855324","https://openalex.org/W1627893155","https://openalex.org/W1966635891","https://openalex.org/W1992617085","https://openalex.org/W1999260196","https://openalex.org/W2012741371","https://openalex.org/W2018270544","https://openalex.org/W2020479800","https://openalex.org/W2049775136","https://openalex.org/W2059113574","https://openalex.org/W2097624341","https://openalex.org/W2138180048","https://openalex.org/W2262964675","https://openalex.org/W2275418539","https://openalex.org/W2402951126","https://openalex.org/W2405814241","https://openalex.org/W2412739544","https://openalex.org/W2489590461","https://openalex.org/W2795696357","https://openalex.org/W4376523630"],"related_works":["https://openalex.org/W2109060290","https://openalex.org/W1965451195","https://openalex.org/W7095138627","https://openalex.org/W2609384725","https://openalex.org/W2136012536","https://openalex.org/W2002626014","https://openalex.org/W1987335784","https://openalex.org/W2057355377","https://openalex.org/W1864944252","https://openalex.org/W2737566970"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}