{"id":"https://openalex.org/W2076750409","doi":"https://doi.org/10.1016/j.antiviral.2009.02.059","title":"Prophylactic Efficacy of Intranasally Administered HSP Nanoparticles for Treating a Lethal SARS-CoV Infection in BALB/c Mice","display_name":"Prophylactic Efficacy of Intranasally Administered HSP Nanoparticles for Treating a Lethal SARS-CoV Infection in BALB/c Mice","publication_year":2009,"publication_date":"2009-05-01","ids":{"openalex":"https://openalex.org/W2076750409","doi":"https://doi.org/10.1016/j.antiviral.2009.02.059","mag":"2076750409"},"language":"en","primary_location":{"id":"doi:10.1016/j.antiviral.2009.02.059","doi":"https://doi.org/10.1016/j.antiviral.2009.02.059","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.antiviral.2009.02.059","pdf_url":null,"source":{"id":"https://openalex.org/S137372404","display_name":"Antiviral Research","issn_l":"0166-3542","issn":["0166-3542","1872-9096"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antiviral Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7134289","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068456155","display_name":"Dale L. Barnard","orcid":"https://orcid.org/0000-0002-4505-020X","observed_orcids":["https://orcid.org/0000-0002-4505-020X"]},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dale Barnard","raw_affiliation_strings":["Utah State University, Logan, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Utah State University, Logan, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"middle","author":{"id":null,"display_name":"James Wiley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Wiley","raw_affiliation_strings":["Montana State University, Bozeman, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Montana State University, Bozeman, USA","institution_ids":["https://openalex.org/I23732399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021948435","display_name":"Miles K. Wandersee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miles Wandersee","raw_affiliation_strings":["Utah State University, Logan, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Utah State University, Logan, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062162666","display_name":"Yohichi Kumaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yohichi Kumaki","raw_affiliation_strings":["Utah State University, Logan, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Utah State University, Logan, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006725047","display_name":"Mark Young","orcid":"https://orcid.org/0000-0001-8069-9840","observed_orcids":["https://orcid.org/0000-0001-8069-9840"]},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Young","raw_affiliation_strings":["Montana State University, Bozeman, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Montana State University, Bozeman, USA","institution_ids":["https://openalex.org/I23732399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052644960","display_name":"Trevor Douglas","orcid":"https://orcid.org/0000-0002-7882-2704","observed_orcids":["https://orcid.org/0000-0002-7882-2704"]},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trevor Douglas","raw_affiliation_strings":["Montana State University, Bozeman, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Montana State University, Bozeman, USA","institution_ids":["https://openalex.org/I23732399"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047442745","display_name":"Allan Harmsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23732399","display_name":"Montana State University","ror":"https://ror.org/02w0trx84","country_code":"US","type":"education","lineage":["https://openalex.org/I23732399","https://openalex.org/I4210126032"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allan Harmsen","raw_affiliation_strings":["Montana State University, Bozeman, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Montana State University, Bozeman, USA","institution_ids":["https://openalex.org/I23732399"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068456155"],"corresponding_institution_ids":["https://openalex.org/I121980950"],"apc_list":{"value":4160,"currency":"USD","value_usd":4160},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.17813985,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"82","issue":"2","first_page":"A32","last_page":"A32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.007699999958276749,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heat-shock-proteins","display_name":"heat shock proteins","score":0.6460000276565552},{"id":"https://openalex.org/keywords/intranasal-administration","display_name":"intranasal administration","score":0.8730000257492065},{"id":"https://openalex.org/keywords/sars-cov","display_name":"SARS-CoV","score":0.8510000109672546},{"id":"https://openalex.org/keywords/prophylaxis","display_name":"prophylaxis","score":0.8330000042915344},{"id":"https://openalex.org/keywords/nanoparticle-based-vaccines","display_name":"nanoparticle vaccine","score":0.5180000066757202},{"id":"https://openalex.org/keywords/balb-c-mice","display_name":"BALB/c mice","score":0.7730000019073486},{"id":"https://openalex.org/keywords/viral-infection","display_name":"viral infection","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C85663871","wikidata":"https://www.wikidata.org/wiki/Q6966562","display_name":"Nasal administration","level":2,"score":0.8819845914840698},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6349685192108154},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5562046766281128},{"id":"https://openalex.org/C2776529007","wikidata":"https://www.wikidata.org/wiki/Q9820","display_name":"BALB/c","level":3,"score":0.5413451194763184},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.5255290865898132},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5230159163475037},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.4248335063457489},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.41030117869377136},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.15002569556236267},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12629881501197815},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.10662403702735901},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.1035546064376831},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.antiviral.2009.02.059","doi":"https://doi.org/10.1016/j.antiviral.2009.02.059","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.antiviral.2009.02.059","pdf_url":null,"source":{"id":"https://openalex.org/S137372404","display_name":"Antiviral Research","issn_l":"0166-3542","issn":["0166-3542","1872-9096"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antiviral Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7134289","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7134289","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antiviral Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7134289","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7134289","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antiviral Res","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7111654523","https://openalex.org/W1999008826","https://openalex.org/W4391022518","https://openalex.org/W2560290744","https://openalex.org/W3205090915","https://openalex.org/W3086379599","https://openalex.org/W1966683713","https://openalex.org/W4411428685","https://openalex.org/W2342601274","https://openalex.org/W4385293552"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}