{"id":"https://openalex.org/W2076482318","doi":"https://doi.org/10.1016/j.jacc.2007.03.025","title":"Patients With Prior Myocardial Infarction, Stroke, or Symptomatic Peripheral Arterial Disease in the CHARISMA Trial","display_name":"Patients With Prior Myocardial Infarction, Stroke, or Symptomatic Peripheral Arterial Disease in the CHARISMA Trial","publication_year":2007,"publication_date":"2007-04-12","ids":{"openalex":"https://openalex.org/W2076482318","doi":"https://doi.org/10.1016/j.jacc.2007.03.025","mag":"2076482318","pmid":"https://pubmed.ncbi.nlm.nih.gov/17498584"},"language":"en","primary_location":{"id":"doi:10.1016/j.jacc.2007.03.025","doi":"https://doi.org/10.1016/j.jacc.2007.03.025","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2007.03.025","pdf_url":null,"source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.jacc.2007.03.025","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010571732","display_name":"Deepak L. Bhatt","orcid":"https://orcid.org/0000-0002-1278-6245","observed_orcids":["https://orcid.org/0000-0002-1278-6245","https://orcid.org/0000-0003-0487-7531"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Deepak L. Bhatt","raw_affiliation_strings":["Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA. bhattd@ccf.org","Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA. bhattd@ccf.org","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037858868","display_name":"Marcus D Flather","orcid":"https://orcid.org/0000-0001-5644-3116","observed_orcids":["https://orcid.org/0000-0001-5644-3116"]},"institutions":[{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Marcus D. Flather","raw_affiliation_strings":["Clinical Trials and Evaluation Unit, Royal Brompton Hospital, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Trials and Evaluation Unit, Royal Brompton Hospital, London, United Kingdom","institution_ids":["https://openalex.org/I4210096640"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108088827","display_name":"Werner Hacke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Werner Hacke","raw_affiliation_strings":["Department of Neurology, University of Heidelberg, Heidelberg, Germany","Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]},{"raw_affiliation_string":"Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111624150","display_name":"Peter B. Berger","orcid":"https://orcid.org/0000-0002-3249-8240","observed_orcids":["https://orcid.org/0000-0002-3249-8240"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter B. Berger","raw_affiliation_strings":["Geisinger Center for Health Research, Danville, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Geisinger Center for Health Research, Danville, Pennsylvania","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108779552","display_name":"Henry Richard Black","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Henry R. Black","raw_affiliation_strings":["New York University School of Medicine, New York, New York","New York University School of Medicine New York New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University School of Medicine, New York, New York","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York University School of Medicine New York New York","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069006768","display_name":"William E. Boden","orcid":"https://orcid.org/0000-0001-7145-8084","observed_orcids":["https://orcid.org/0000-0001-7145-8084"]},"institutions":[{"id":"https://openalex.org/I1325611130","display_name":"Kaleida Health","ror":"https://ror.org/02sb3pg33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1325611130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William E. Boden","raw_affiliation_strings":["Division of Cardiology, Kaleida Healthcare, Buffalo, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Kaleida Healthcare, Buffalo, New York","institution_ids":["https://openalex.org/I1325611130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037078532","display_name":"P. Cacoub","orcid":"https://orcid.org/0000-0002-6727-4992","observed_orcids":["https://orcid.org/0000-0002-6727-4992"]},"institutions":[{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Patrice Cacoub","raw_affiliation_strings":["Department of Internal Medicine, Hopital Pitie-Salpetriere, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Hopital Pitie-Salpetriere, Paris, France","institution_ids":["https://openalex.org/I4210121705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101573678","display_name":"Eric A. Cohen","orcid":"https://orcid.org/0000-0001-6243-0186","observed_orcids":["https://orcid.org/0000-0001-6243-0186"]},"institutions":[{"id":"https://openalex.org/I1323843004","display_name":"Sunnybrook Health Science Centre","ror":"https://ror.org/03wefcv03","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Eric A. Cohen","raw_affiliation_strings":["Division of Cardiology, Sunnybrook and Women\u2019s College Health Science Centre, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Sunnybrook and Women\u2019s College Health Science Centre, Toronto, Canada","institution_ids":["https://openalex.org/I1323843004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056183044","display_name":"Mark A. Creager","orcid":"https://orcid.org/0000-0001-9758-6447","observed_orcids":["https://orcid.org/0000-0001-9758-6447"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark A. Creager","raw_affiliation_strings":["Division of Cardiovascular Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts","Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040093844","display_name":"J. Donald Easton","orcid":"https://orcid.org/0000-0002-8039-805X","observed_orcids":["https://orcid.org/0000-0002-8039-805X"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Donald Easton","raw_affiliation_strings":["Department of Neurology, Rhode Island Hospital and Brown University, Providence, Rhode Island"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Rhode Island Hospital and Brown University, Providence, Rhode Island","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I2800446032"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010936003","display_name":"Christian W. Hamm","orcid":"https://orcid.org/0000-0001-6763-4161","observed_orcids":["https://orcid.org/0000-0001-6763-4161"]},"institutions":[{"id":"https://openalex.org/I4210133626","display_name":"Kerckhoff Klinik","ror":"https://ror.org/04m54m956","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210133626"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian W. Hamm","raw_affiliation_strings":["Department of Cardiology, Kerckhoff-Klinik Center, Bad Nauheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Kerckhoff-Klinik Center, Bad Nauheim, Germany","institution_ids":["https://openalex.org/I4210133626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014800121","display_name":"Graeme J. Hankey","orcid":"https://orcid.org/0000-0002-6044-7328","observed_orcids":["https://orcid.org/0000-0002-6044-7328"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2799740997","display_name":"Royal Perth Hospital","ror":"https://ror.org/00zc2xc51","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2799740997","https://openalex.org/I2800882159","https://openalex.org/I4388446364","https://openalex.org/I4405257575"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Graeme J. Hankey","raw_affiliation_strings":["Department of Neurology, Royal Perth Hospital and School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Royal Perth Hospital and School of Medicine and Pharmacology, The University of Western Australia, Perth, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2799740997"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001594817","display_name":"S. Claiborne Johnston","orcid":"https://orcid.org/0000-0002-2912-0714","observed_orcids":["https://orcid.org/0000-0002-2912-0714"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Claiborne Johnston","raw_affiliation_strings":["Department of Neurology, University of California San Francisco, San Francisco, California","Department of Neurology, University of California San Francisco, San Francisco California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of California San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Neurology, University of California San Francisco, San Francisco California","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110149029","display_name":"Koon\u2010Hou Mak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801414801","display_name":"Gleneagles Hospital","ror":"https://ror.org/0176wfg98","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2801414801"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Koon-Hou Mak","raw_affiliation_strings":["Gleneagles Medical Centre, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gleneagles Medical Centre, Singapore","institution_ids":["https://openalex.org/I2801414801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026157924","display_name":"Jean\u2010Louis Mas","orcid":"https://orcid.org/0000-0003-4891-3127","observed_orcids":["https://orcid.org/0000-0003-4891-3127"]},"institutions":[{"id":"https://openalex.org/I4210124863","display_name":"Centre Hospitalier Sainte-Anne","ror":"https://ror.org/02kxjxy06","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210124863"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Louis Mas","raw_affiliation_strings":["Department of Neurology and Stroke Unit, Sainte-Anne Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology and Stroke Unit, Sainte-Anne Hospital, Paris, France","institution_ids":["https://openalex.org/I4210124863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027244910","display_name":"Gilles Montalescot","orcid":"https://orcid.org/0000-0003-0824-6809","observed_orcids":["https://orcid.org/0000-0003-0824-6809"]},"institutions":[{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gilles Montalescot","raw_affiliation_strings":["Institut de Cardiologie \u2014 Centre Hospitalier Universitaire Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de Cardiologie \u2014 Centre Hospitalier Universitaire Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France","institution_ids":["https://openalex.org/I4210121705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107832652","display_name":"Thomas A. Pearson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas A. Pearson","raw_affiliation_strings":["Department of Community & Preventive Medicine, University of Rochester School of Medicine, Rochester, New York","Department of Community and Preventive Medicine, University of Rochester School of Medicine, Rochester, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Community & Preventive Medicine, University of Rochester School of Medicine, Rochester, New York","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"raw_affiliation_string":"Department of Community and Preventive Medicine, University of Rochester School of Medicine, Rochester, New York","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003831287","display_name":"Philippe Gabr\u00edel Steg","orcid":"https://orcid.org/0000-0001-6896-2941","observed_orcids":["https://orcid.org/0000-0001-6896-2941"]},"institutions":[{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210145170","display_name":"H\u00f4pital Bichat-Claude-Bernard","ror":"https://ror.org/03fdnmv92","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210145170"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P. Gabriel Steg","raw_affiliation_strings":["Service de Cardiologie, H\u00f4pital Bichat, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de Cardiologie, H\u00f4pital Bichat, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210145170"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054364960","display_name":"Steven R. Steinhubl","orcid":"https://orcid.org/0000-0002-9256-7914","observed_orcids":["https://orcid.org/0000-0002-9256-7914"]},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven R. Steinhubl","raw_affiliation_strings":["Division of Cardiology, University of Kentucky, Lexington, Kentucky"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, University of Kentucky, Lexington, Kentucky","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042851664","display_name":"Michael A. Weber","orcid":"https://orcid.org/0000-0002-8504-0831","observed_orcids":["https://orcid.org/0000-0002-8504-0831"]},"institutions":[{"id":"https://openalex.org/I181697535","display_name":"SUNY Downstate Health Sciences University","ror":"https://ror.org/0041qmd21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181697535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. Weber","raw_affiliation_strings":["SUNY Downstate Medical Center College of Medicine, Brooklyn, New York","SUNY Downstate Medical Center, College of Medicine, Brooklyn, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SUNY Downstate Medical Center College of Medicine, Brooklyn, New York","institution_ids":["https://openalex.org/I181697535"]},{"raw_affiliation_string":"SUNY Downstate Medical Center, College of Medicine, Brooklyn, New York","institution_ids":["https://openalex.org/I181697535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036149166","display_name":"Liz Fabry-Ribaudo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liz Fabry-Ribaudo","raw_affiliation_strings":["Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113636435","display_name":"Tingfei Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tingfei Hu","raw_affiliation_strings":["Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084515381","display_name":"Eric J. Topol","orcid":"https://orcid.org/0000-0002-1478-4729","observed_orcids":["https://orcid.org/0000-0002-1478-4729"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric J. Topol","raw_affiliation_strings":["Case Western Reserve University; Cleveland Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University; Cleveland Ohio","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039466154","display_name":"Keith A.A. Fox","orcid":"https://orcid.org/0000-0002-0140-2752","observed_orcids":["https://orcid.org/0000-0002-0140-2752"]},"institutions":[{"id":"https://openalex.org/I2802789809","display_name":"Edinburgh Royal Infirmary","ror":"https://ror.org/009bsy196","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802789809"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Keith A.A. Fox","raw_affiliation_strings":["University and Royal Infirmary of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University and Royal Infirmary of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I2802789809"]}]}],"institutions":[],"countries_distinct_count":7,"institutions_distinct_count":25,"corresponding_author_ids":["https://openalex.org/A5010571732"],"corresponding_institution_ids":["https://openalex.org/I1316902750"],"apc_list":{"value":7166,"currency":"USD","value_usd":7166},"apc_paid":null,"fwci":43.6256,"has_fulltext":false,"cited_by_count":805,"citation_normalized_percentile":{"value":0.99868312,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"49","issue":"19","first_page":"1982","last_page":"1988"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dual-antiplatelet-therapy","display_name":"dual antiplatelet therapy","score":0.9940000176429749},{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.9829999804496765},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/prior-myocardial-infarction","display_name":"old myocardial infarction","score":0.9089999794960022},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9959999918937683},{"id":"https://openalex.org/keywords/symptomatic-peripheral-arterial-disease","display_name":"symptomatic peripheral arterial disease","score":0.9800000190734863},{"id":"https://openalex.org/keywords/charisma-trial","display_name":"CHARISMA trial","score":0.9449999928474426},{"id":"https://openalex.org/keywords/secondary-prevention","display_name":"secondary prevention","score":0.6800000071525574},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.6129999756813049},{"id":"https://openalex.org/keywords/bleeding-complications","display_name":"bleeding complications","score":0.7009999752044678},{"id":"https://openalex.org/keywords/subgroup-analysis","display_name":"subgroup analysis","score":0.5189999938011169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9782372117042542},{"id":"https://openalex.org/C2777849778","wikidata":"https://www.wikidata.org/wiki/Q410237","display_name":"Clopidogrel","level":3,"score":0.7874575257301331},{"id":"https://openalex.org/C2777628954","wikidata":"https://www.wikidata.org/wiki/Q18216","display_name":"Aspirin","level":2,"score":0.7798013687133789},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.6757892370223999},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6713322997093201},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.6679049730300903},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.6639349460601807},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5462768077850342},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5197493433952332},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.49368008971214294},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.35008153319358826},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077144","descriptor_name":"Clopidogrel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077144","descriptor_name":"Clopidogrel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077144","descriptor_name":"Clopidogrel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001241","descriptor_name":"Aspirin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001241","descriptor_name":"Aspirin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001241","descriptor_name":"Aspirin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D013988","descriptor_name":"Ticlopidine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.jacc.2007.03.025","doi":"https://doi.org/10.1016/j.jacc.2007.03.025","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2007.03.025","pdf_url":null,"source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},{"id":"pmid:17498584","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17498584","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/73fa45de-5f99-42cb-83b5-80a754fcb663","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/73fa45de-5f99-42cb-83b5-80a754fcb663","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ricerca.uniba.it:11586/10547","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11586/10547","pdf_url":null,"source":{"id":"https://openalex.org/S4377196296","display_name":"CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5561750","host_organization_name":"University of Bari Aldo Moro","host_organization_lineage":["https://openalex.org/I5561750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ueaeprints.uea.ac.uk:46272","doi":null,"is_oa":false,"landing_page_url":"https://ueaeprints.uea.ac.uk/id/eprint/46272/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400384","display_name":"UEA Digital Repository (University of East Anglia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1118541","host_organization_name":"University of East Anglia","host_organization_lineage":["https://openalex.org/I1118541"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/j.jacc.2007.03.025","doi":"https://doi.org/10.1016/j.jacc.2007.03.025","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2007.03.025","pdf_url":null,"source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6899999976158142}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307781","display_name":"Sanofi","ror":"https://ror.org/027vj4x92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W311320695","https://openalex.org/W1553345686","https://openalex.org/W1596397105","https://openalex.org/W1996134888","https://openalex.org/W2004235420","https://openalex.org/W2053379248","https://openalex.org/W2084673482","https://openalex.org/W2100209149","https://openalex.org/W2106822998","https://openalex.org/W2107797912","https://openalex.org/W2147319349","https://openalex.org/W2162886638","https://openalex.org/W2529190803"],"related_works":["https://openalex.org/W2279508388","https://openalex.org/W2129507256","https://openalex.org/W2018700837","https://openalex.org/W2370813820","https://openalex.org/W1983076760","https://openalex.org/W2410339737","https://openalex.org/W2086674965","https://openalex.org/W2359827248","https://openalex.org/W4242658903","https://openalex.org/W2883947381"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":22},{"year":2021,"cited_by_count":30},{"year":2020,"cited_by_count":52},{"year":2019,"cited_by_count":41},{"year":2018,"cited_by_count":62},{"year":2017,"cited_by_count":65},{"year":2016,"cited_by_count":60},{"year":2015,"cited_by_count":46},{"year":2014,"cited_by_count":37},{"year":2013,"cited_by_count":35},{"year":2012,"cited_by_count":45}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}