{"id":"https://openalex.org/W2076248141","doi":"https://doi.org/10.1016/0091-3057(93)90335-q","title":"Benzodiazepine receptor-mediated behavioral effects of nitrous oxide in the rat social interaction test","display_name":"Benzodiazepine receptor-mediated behavioral effects of nitrous oxide in the rat social interaction test","publication_year":1993,"publication_date":"1993-09-01","ids":{"openalex":"https://openalex.org/W2076248141","doi":"https://doi.org/10.1016/0091-3057(93)90335-q","mag":"2076248141","pmid":"https://pubmed.ncbi.nlm.nih.gov/8255907"},"language":"en","primary_location":{"id":"doi:10.1016/0091-3057(93)90335-q","doi":"https://doi.org/10.1016/0091-3057(93)90335-q","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0091-3057(93)90335-q","pdf_url":null,"source":{"id":"https://openalex.org/S59685179","display_name":"Pharmacology Biochemistry and Behavior","issn_l":"0091-3057","issn":["0091-3057","1873-5177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacology Biochemistry and Behavior","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015469925","display_name":"Raymond Mark Quock","orcid":"https://orcid.org/0000-0001-6616-4778","observed_orcids":["https://orcid.org/0000-0001-6616-4778"]},"institutions":[{"id":"https://openalex.org/I4210110323","display_name":"University of Illinois Chicago, Rockford campus","ror":"https://ror.org/02437s643","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210110323"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Raymond M. Quock","raw_affiliation_strings":["Department of Biomedical Sciences, University of Illinois, College of Medicine at Rockford 61107"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Illinois, College of Medicine at Rockford 61107","institution_ids":["https://openalex.org/I4210110323"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089003701","display_name":"Pamela J. Wetzel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110323","display_name":"University of Illinois Chicago, Rockford campus","ror":"https://ror.org/02437s643","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210110323"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela J. Wetzel","raw_affiliation_strings":["Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA","institution_ids":["https://openalex.org/I4210110323"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036443067","display_name":"R.H. Maillefer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110323","display_name":"University of Illinois Chicago, Rockford campus","ror":"https://ror.org/02437s643","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210110323"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rog\u00e9r H. Maillefer","raw_affiliation_strings":["Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA","institution_ids":["https://openalex.org/I4210110323"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044644907","display_name":"Bradley L. Hodges","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110323","display_name":"University of Illinois Chicago, Rockford campus","ror":"https://ror.org/02437s643","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210110323"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bradley L. Hodges","raw_affiliation_strings":["Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA","institution_ids":["https://openalex.org/I4210110323"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073426839","display_name":"Bradley A. Curtis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110323","display_name":"University of Illinois Chicago, Rockford campus","ror":"https://ror.org/02437s643","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210110323"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bradley A. Curtis","raw_affiliation_strings":["Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA","institution_ids":["https://openalex.org/I4210110323"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009717381","display_name":"Donald A. Czech","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102461120","display_name":"Marquette University","ror":"https://ror.org/04gr4te78","country_code":"US","type":"education","lineage":["https://openalex.org/I102461120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald A. Czech","raw_affiliation_strings":["Department of Psychology, Marquette University, Milwaukee, WI 53233, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, Marquette University, Milwaukee, WI 53233, USA","institution_ids":["https://openalex.org/I102461120"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015469925"],"corresponding_institution_ids":["https://openalex.org/I4210110323"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":null,"fwci":2.4416,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.87877991,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"46","issue":"1","first_page":"161","last_page":"165"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.3659999966621399,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.3659999966621399,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.31790000200271606,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.19059999287128448,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitrous-oxide","display_name":"nitrous oxide","score":1.0},{"id":"https://openalex.org/keywords/benzodiazepine-receptor","display_name":"benzodiazepine receptor","score":0.9599999785423279},{"id":"https://openalex.org/keywords/anxiolytic-effects","display_name":"anxiolytic effects","score":0.9070000052452087},{"id":"https://openalex.org/keywords/social-interaction","display_name":"social interaction","score":0.9229999780654907},{"id":"https://openalex.org/keywords/chlordiazepoxide","display_name":"chlordiazepoxide","score":0.9549999833106995},{"id":"https://openalex.org/keywords/flumazenil","display_name":"flumazenil","score":0.996999979019165},{"id":"https://openalex.org/keywords/sedation","display_name":"sedation","score":0.7889999747276306},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C2778325228","wikidata":"https://www.wikidata.org/wiki/Q178566","display_name":"Chlordiazepoxide","level":3,"score":0.9031174182891846},{"id":"https://openalex.org/C2778409475","wikidata":"https://www.wikidata.org/wiki/Q421920","display_name":"Flumazenil","level":4,"score":0.8663655519485474},{"id":"https://openalex.org/C2777573673","wikidata":"https://www.wikidata.org/wiki/Q905750","display_name":"Nitrous oxide","level":2,"score":0.7995280623435974},{"id":"https://openalex.org/C2778173252","wikidata":"https://www.wikidata.org/wiki/Q83871","display_name":"Benzodiazepine","level":3,"score":0.7991087436676025},{"id":"https://openalex.org/C2777765862","wikidata":"https://www.wikidata.org/wiki/Q62903","display_name":"Anxiolytic","level":3,"score":0.6545652747154236},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5849029421806335},{"id":"https://openalex.org/C2776175493","wikidata":"https://www.wikidata.org/wiki/Q210402","display_name":"Diazepam","level":2,"score":0.5294857621192932},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5234783887863159},{"id":"https://openalex.org/C168258287","wikidata":"https://www.wikidata.org/wiki/Q60147","display_name":"GABAA receptor","level":3,"score":0.4636908769607544},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.35931694507598877},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3517330288887024},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.33390337228775024},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2398134171962738},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0901837944984436}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D002707","descriptor_name":"Chlordiazepoxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005442","descriptor_name":"Flumazenil","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007398","descriptor_name":"Interpersonal Relations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009609","descriptor_name":"Nitrous Oxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058787","descriptor_name":"GABA-A Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0091-3057(93)90335-q","doi":"https://doi.org/10.1016/0091-3057(93)90335-q","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0091-3057(93)90335-q","pdf_url":null,"source":{"id":"https://openalex.org/S59685179","display_name":"Pharmacology Biochemistry and Behavior","issn_l":"0091-3057","issn":["0091-3057","1873-5177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacology Biochemistry and Behavior","raw_type":"journal-article"},{"id":"pmid:8255907","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8255907","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacology, biochemistry, and behavior","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3059173629","display_name":null,"funder_award_id":"DE-09378","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G6197563910","display_name":"NITROUS OXIDE CONSCIOUS SEDATION--ANXIOYSIS","funder_award_id":"1r03de009378-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1608149862","https://openalex.org/W1981219928","https://openalex.org/W1988307857","https://openalex.org/W2011797714","https://openalex.org/W2023282221","https://openalex.org/W2036096547","https://openalex.org/W2039542537","https://openalex.org/W2056760270","https://openalex.org/W2059354993","https://openalex.org/W2084882106","https://openalex.org/W2108612481","https://openalex.org/W2117164661","https://openalex.org/W2122122994","https://openalex.org/W2178648866","https://openalex.org/W2401815609","https://openalex.org/W2401895158"],"related_works":["https://openalex.org/W2011797714","https://openalex.org/W1967623697","https://openalex.org/W1967168120","https://openalex.org/W2413525810","https://openalex.org/W1977895422","https://openalex.org/W2087739403","https://openalex.org/W2085051045","https://openalex.org/W2067258010","https://openalex.org/W1973368707","https://openalex.org/W2098638088"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}