{"id":"https://openalex.org/W2075815682","doi":"https://doi.org/10.1007/bf00199723","title":"Immune response of mice exposed to cis-diamminedichloroplatinum","display_name":"Immune response of mice exposed to cis-diamminedichloroplatinum","publication_year":1985,"publication_date":"1985-04-01","ids":{"openalex":"https://openalex.org/W2075815682","doi":"https://doi.org/10.1007/bf00199723","mag":"2075815682","pmid":"https://pubmed.ncbi.nlm.nih.gov/3157438","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11039269"},"language":"en","primary_location":{"id":"doi:10.1007/bf00199723","doi":"https://doi.org/10.1007/bf00199723","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00199723","pdf_url":null,"source":{"id":"https://openalex.org/S203303425","display_name":"Cancer Immunology Immunotherapy","issn_l":"0340-7004","issn":["0340-7004","1432-0851"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Immunology Immunotherapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11039269","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035940340","display_name":"Omar Bagasra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2803028891","display_name":"Hahnemann University Hospital","ror":"https://ror.org/016bbv872","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2803028891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omar Bagasra","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I2803028891"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I2803028891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074673918","display_name":"Linda Currao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2803028891","display_name":"Hahnemann University Hospital","ror":"https://ror.org/016bbv872","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2803028891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linda Currao","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I2803028891"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I2803028891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039791188","display_name":"Lesley Desouza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2803028891","display_name":"Hahnemann University Hospital","ror":"https://ror.org/016bbv872","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2803028891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"LuisR. DeSouza","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I2803028891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011584764","display_name":"J. Wolter Oosterhuis","orcid":"https://orcid.org/0000-0002-6685-686X","observed_orcids":["https://orcid.org/0000-0002-6685-686X"]},"institutions":[{"id":"https://openalex.org/I2803028891","display_name":"Hahnemann University Hospital","ror":"https://ror.org/016bbv872","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2803028891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.Wolter Oosterhuis","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I2803028891"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I2803028891"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051722819","display_name":"Ivan Damjanov","orcid":"https://orcid.org/0000-0002-1394-6052","observed_orcids":["https://orcid.org/0000-0002-1394-6052"]},"institutions":[{"id":"https://openalex.org/I2803028891","display_name":"Hahnemann University Hospital","ror":"https://ror.org/016bbv872","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2803028891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ivan Damjanov","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, 19102-1192, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I2803028891"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Hahnemann University School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I2803028891"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2803028891"],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":0.4912,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.6307438,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"2","first_page":"142","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.9459999799728394},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.8140000104904175},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9330000281333923},{"id":"https://openalex.org/keywords/lymphoid-organs","display_name":"lymphoid organs","score":0.8040000200271606},{"id":"https://openalex.org/keywords/splenic-plaque-forming-cells","display_name":"splenic plaque-forming cells","score":0.8550000190734863},{"id":"https://openalex.org/keywords/t-cell-dependent-antigens","display_name":"T-dependent antigens","score":0.5609999895095825},{"id":"https://openalex.org/keywords/t-independent-antigens","display_name":"T-independent antigens","score":0.9909999966621399},{"id":"https://openalex.org/keywords/age-dependent-effects","display_name":"age-dependent effects","score":0.5630000233650208},{"id":"https://openalex.org/keywords/dose-dependent-effects","display_name":"dose-dependent effects","score":0.7630000114440918},{"id":"https://openalex.org/keywords/t-cell-depletion","display_name":"T cell depletion","score":0.7649999856948853},{"id":"https://openalex.org/keywords/b-cell-depletion","display_name":"B-cell depletion","score":0.9959999918937683},{"id":"https://openalex.org/keywords/thymus","display_name":"thymus","score":0.8149999976158142},{"id":"https://openalex.org/keywords/lymph-nodes","display_name":"lymph nodes","score":0.9359999895095825},{"id":"https://openalex.org/keywords/spleen","display_name":"spleen","score":0.8040000200271606},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.5540000200271606}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.8502347469329834},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.8428085446357727},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.7536193132400513},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.649559736251831},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.521757185459137},{"id":"https://openalex.org/C181152851","wikidata":"https://www.wikidata.org/wiki/Q712604","display_name":"Lymphatic system","level":2,"score":0.515200674533844},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.45387381315231323},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.4500022530555725},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44609972834587097},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28724583983421326},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1354888677597046}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000955","descriptor_name":"Antigens, T-Independent","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006377","descriptor_name":"T-Lymphocytes, Helper-Inducer","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006377","descriptor_name":"T-Lymphocytes, Helper-Inducer","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008208","descriptor_name":"Lymphatic System","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D008208","descriptor_name":"Lymphatic System","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D050378","descriptor_name":"T-Lymphocytes, Regulatory","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/bf00199723","doi":"https://doi.org/10.1007/bf00199723","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00199723","pdf_url":null,"source":{"id":"https://openalex.org/S203303425","display_name":"Cancer Immunology Immunotherapy","issn_l":"0340-7004","issn":["0340-7004","1432-0851"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Immunology Immunotherapy","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11039269","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11039269","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Immunol Immunother","raw_type":"Text"},{"id":"pmid:3157438","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3157438","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer immunology, immunotherapy : CII","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11039269","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11039269","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Immunol Immunother","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4111315368","display_name":null,"funder_award_id":"CA-23097","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G478084625","display_name":null,"funder_award_id":"CA 38405","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W167981432","https://openalex.org/W1476207571","https://openalex.org/W1525919172","https://openalex.org/W1566014256","https://openalex.org/W1628384779","https://openalex.org/W1684880136","https://openalex.org/W1808208212","https://openalex.org/W1964532737","https://openalex.org/W1978785687","https://openalex.org/W1983388313","https://openalex.org/W2007812018","https://openalex.org/W2008647477","https://openalex.org/W2015257039","https://openalex.org/W2015705392","https://openalex.org/W2036060573","https://openalex.org/W2036182567","https://openalex.org/W2040984019","https://openalex.org/W2046648691","https://openalex.org/W2082315905","https://openalex.org/W2088381124","https://openalex.org/W2101195702","https://openalex.org/W2114193271","https://openalex.org/W2124860442","https://openalex.org/W2136025868","https://openalex.org/W2139804369","https://openalex.org/W2194368740","https://openalex.org/W2314001387","https://openalex.org/W2395599374","https://openalex.org/W2422264815","https://openalex.org/W4300430814"],"related_works":["https://openalex.org/W1988233362","https://openalex.org/W2004043062","https://openalex.org/W2424305107","https://openalex.org/W1699306240","https://openalex.org/W2070236426","https://openalex.org/W36081160","https://openalex.org/W2142571475","https://openalex.org/W50624548","https://openalex.org/W2014804941","https://openalex.org/W2012224873"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}