{"id":"https://openalex.org/W2075814735","doi":"https://doi.org/10.1248/cpb.56.1628","title":"Medicinal Flowers. XXIII. New Taraxastane-Type Triterpene, Punicanolic Acid, with Tumor Necrosis Factor-.ALPHA. Inhibitory Activity from the Flowers of Punica granatum","display_name":"Medicinal Flowers. XXIII. New Taraxastane-Type Triterpene, Punicanolic Acid, with Tumor Necrosis Factor-.ALPHA. Inhibitory Activity from the Flowers of Punica granatum","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2075814735","doi":"https://doi.org/10.1248/cpb.56.1628","mag":"2075814735","pmid":"https://pubmed.ncbi.nlm.nih.gov/18981621"},"language":"en","primary_location":{"id":"doi:10.1248/cpb.56.1628","doi":"https://doi.org/10.1248/cpb.56.1628","is_oa":true,"landing_page_url":"https://doi.org/10.1248/cpb.56.1628","pdf_url":"https://www.jstage.jst.go.jp/article/cpb/56/11/56_11_1628/_pdf","source":{"id":"https://openalex.org/S3861430","display_name":"Chemical and Pharmaceutical Bulletin","issn_l":"0009-2363","issn":["0009-2363","1347-5223"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical and Pharmaceutical Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/cpb/56/11/56_11_1628/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101651697","display_name":"Yuanyuan Xie","orcid":"https://orcid.org/0000-0001-5374-0094","observed_orcids":["https://orcid.org/0000-0001-5374-0094"]},"institutions":[{"id":"https://openalex.org/I103890011","display_name":"Shenyang Pharmaceutical University","ror":"https://ror.org/03dnytd23","country_code":"CN","type":"education","lineage":["https://openalex.org/I103890011"]},{"id":"https://openalex.org/I916559398","display_name":"Kindai University","ror":"https://ror.org/05kt9ap64","country_code":"JP","type":"education","lineage":["https://openalex.org/I916559398"]}],"countries":["CN","JP"],"is_corresponding":false,"raw_author_name":"Yuanyuan Xie","raw_affiliation_strings":["Pharmaceutical Research and Technology Institute, Kinki University","School of Traditional Chinese Medicine, Shenyang Pharmaceutical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Research and Technology Institute, Kinki University","institution_ids":["https://openalex.org/I916559398"]},{"raw_affiliation_string":"School of Traditional Chinese Medicine, Shenyang Pharmaceutical University","institution_ids":["https://openalex.org/I103890011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031585366","display_name":"Toshio Morikawa","orcid":"https://orcid.org/0000-0003-2794-5365","observed_orcids":["https://orcid.org/0000-0003-2794-5365"]},"institutions":[{"id":"https://openalex.org/I916559398","display_name":"Kindai University","ror":"https://ror.org/05kt9ap64","country_code":"JP","type":"education","lineage":["https://openalex.org/I916559398"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshio Morikawa","raw_affiliation_strings":["Pharmaceutical Research and Technology Institute, Kinki University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Research and Technology Institute, Kinki University","institution_ids":["https://openalex.org/I916559398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010875095","display_name":"Kiyofumi Ninomiya","orcid":"https://orcid.org/0000-0002-5278-7293","observed_orcids":["https://orcid.org/0000-0002-5278-7293"]},"institutions":[{"id":"https://openalex.org/I916559398","display_name":"Kindai University","ror":"https://ror.org/05kt9ap64","country_code":"JP","type":"education","lineage":["https://openalex.org/I916559398"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiyofumi Ninomiya","raw_affiliation_strings":["Pharmaceutical Research and Technology Institute, Kinki University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Research and Technology Institute, Kinki University","institution_ids":["https://openalex.org/I916559398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033945897","display_name":"Katsuya Imura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I916559398","display_name":"Kindai University","ror":"https://ror.org/05kt9ap64","country_code":"JP","type":"education","lineage":["https://openalex.org/I916559398"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuya Imura","raw_affiliation_strings":["Pharmaceutical Research and Technology Institute, Kinki University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Research and Technology Institute, Kinki University","institution_ids":["https://openalex.org/I916559398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002610788","display_name":"Osamu Muraoka","orcid":"https://orcid.org/0000-0002-4947-5651","observed_orcids":["https://orcid.org/0000-0002-4947-5651"]},"institutions":[{"id":"https://openalex.org/I916559398","display_name":"Kindai University","ror":"https://ror.org/05kt9ap64","country_code":"JP","type":"education","lineage":["https://openalex.org/I916559398"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Osamu Muraoka","raw_affiliation_strings":["Pharmaceutical Research and Technology Institute, Kinki University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmaceutical Research and Technology Institute, Kinki University","institution_ids":["https://openalex.org/I916559398"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100747823","display_name":"Dan Yuan","orcid":"https://orcid.org/0000-0002-0695-4046","observed_orcids":["https://orcid.org/0000-0002-0695-4046","https://orcid.org/0000-0002-5620-5457"]},"institutions":[{"id":"https://openalex.org/I103890011","display_name":"Shenyang Pharmaceutical University","ror":"https://ror.org/03dnytd23","country_code":"CN","type":"education","lineage":["https://openalex.org/I103890011"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan Yuan","raw_affiliation_strings":["School of Traditional Chinese Medicine, Shenyang Pharmaceutical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Traditional Chinese Medicine, Shenyang Pharmaceutical University","institution_ids":["https://openalex.org/I103890011"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048821605","display_name":"Masayuki Yoshikawa","orcid":"https://orcid.org/0000-0003-3106-3277","observed_orcids":["https://orcid.org/0000-0003-3106-3277"]},"institutions":[{"id":"https://openalex.org/I25998863","display_name":"Kyoto Pharmaceutical University","ror":"https://ror.org/01ytgve10","country_code":"JP","type":"education","lineage":["https://openalex.org/I25998863"]},{"id":"https://openalex.org/I916559398","display_name":"Kindai University","ror":"https://ror.org/05kt9ap64","country_code":"JP","type":"education","lineage":["https://openalex.org/I916559398"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masayuki Yoshikawa","raw_affiliation_strings":["Kyoto Pharmaceutical University","Pharmaceutical Research and Technology Institute, Kinki University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto Pharmaceutical University","institution_ids":["https://openalex.org/I25998863"]},{"raw_affiliation_string":"Pharmaceutical Research and Technology Institute, Kinki University","institution_ids":["https://openalex.org/I916559398"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.3527,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.87708196,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"56","issue":"11","first_page":"1628","last_page":"1631"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.7182999849319458,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11385","display_name":"Natural product bioactivities and synthesis","score":0.7182999849319458,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12638","display_name":"Pomegranate: compositions and health benefits","score":0.2467000037431717,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.013799999840557575,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pomegranate","display_name":"Punica granatum","score":0.9549999833106995},{"id":"https://openalex.org/keywords/anti-tnf-therapy","display_name":"anti-TNF therapy","score":0.9049999713897705},{"id":"https://openalex.org/keywords/l929-fibroblasts","display_name":"L929 fibroblasts","score":0.9900000095367432},{"id":"https://openalex.org/keywords/flavones","display_name":"flavones","score":0.8059999942779541},{"id":"https://openalex.org/keywords/oleanolic-acid","display_name":"oleanolic acid","score":0.8410000205039978},{"id":"https://openalex.org/keywords/maslinic-acid","display_name":"maslinic acid","score":0.9980000257492065},{"id":"https://openalex.org/keywords/luteolin","display_name":"luteolin","score":0.9449999928474426},{"id":"https://openalex.org/keywords/beta-sitosterol","display_name":"\u03b2-sitosterol","score":0.8949999809265137},{"id":"https://openalex.org/keywords/medicinal-flowers","display_name":"medicinal flowers","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C2778858181","wikidata":"https://www.wikidata.org/wiki/Q418628","display_name":"Oleanolic acid","level":3,"score":0.883479118347168},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8521770238876343},{"id":"https://openalex.org/C2780527577","wikidata":"https://www.wikidata.org/wiki/Q2915788","display_name":"Triterpene","level":3,"score":0.8400349617004395},{"id":"https://openalex.org/C2780125355","wikidata":"https://www.wikidata.org/wiki/Q4959355","display_name":"Punica","level":2,"score":0.6957635283470154},{"id":"https://openalex.org/C160492267","wikidata":"https://www.wikidata.org/wiki/Q319616","display_name":"Pharmacognosy","level":4,"score":0.6025339961051941},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.5996449589729309},{"id":"https://openalex.org/C2779858419","wikidata":"https://www.wikidata.org/wiki/Q407153","display_name":"Ethyl acetate","level":2,"score":0.5952131748199463},{"id":"https://openalex.org/C2776292868","wikidata":"https://www.wikidata.org/wiki/Q424525","display_name":"Flavones","level":2,"score":0.5436457991600037},{"id":"https://openalex.org/C44937612","wikidata":"https://www.wikidata.org/wiki/Q212364","display_name":"Terpene","level":2,"score":0.49859023094177246},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4984862804412842},{"id":"https://openalex.org/C2781464872","wikidata":"https://www.wikidata.org/wiki/Q422044","display_name":"Ellagic acid","level":4,"score":0.4600519835948944},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4481715261936188},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2954792380332947},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.2386818528175354},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.22189673781394958},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.2170771062374115},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.1666528880596161},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.05951008200645447},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002236","descriptor_name":"Carbohydrate Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002240","descriptor_name":"Carbohydrate Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004354","descriptor_name":"Drug Screening Assays, Antitumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013778","descriptor_name":"Tetrazolium Salts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013844","descriptor_name":"Thiazoles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014315","descriptor_name":"Triterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D029561","descriptor_name":"Lythraceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D035264","descriptor_name":"Flowers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1248/cpb.56.1628","doi":"https://doi.org/10.1248/cpb.56.1628","is_oa":true,"landing_page_url":"https://doi.org/10.1248/cpb.56.1628","pdf_url":"https://www.jstage.jst.go.jp/article/cpb/56/11/56_11_1628/_pdf","source":{"id":"https://openalex.org/S3861430","display_name":"Chemical and Pharmaceutical Bulletin","issn_l":"0009-2363","issn":["0009-2363","1347-5223"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical and Pharmaceutical Bulletin","raw_type":"journal-article"},{"id":"pmid:18981621","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18981621","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical & pharmaceutical bulletin","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1248/cpb.56.1628","doi":"https://doi.org/10.1248/cpb.56.1628","is_oa":true,"landing_page_url":"https://doi.org/10.1248/cpb.56.1628","pdf_url":"https://www.jstage.jst.go.jp/article/cpb/56/11/56_11_1628/_pdf","source":{"id":"https://openalex.org/S3861430","display_name":"Chemical and Pharmaceutical Bulletin","issn_l":"0009-2363","issn":["0009-2363","1347-5223"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical and Pharmaceutical Bulletin","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334798","display_name":"Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College","ror":"https://ror.org/042pgcv68"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2075814735.pdf","grobid_xml":"https://content.openalex.org/works/W2075814735.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W5210908","https://openalex.org/W136823849","https://openalex.org/W1606710785","https://openalex.org/W1965152958","https://openalex.org/W1972722981","https://openalex.org/W1974609452","https://openalex.org/W1989878038","https://openalex.org/W1994792408","https://openalex.org/W1999928435","https://openalex.org/W2001016241","https://openalex.org/W2001333050","https://openalex.org/W2001833057","https://openalex.org/W2026892316","https://openalex.org/W2027618337","https://openalex.org/W2030663750","https://openalex.org/W2032225618","https://openalex.org/W2033234194","https://openalex.org/W2035246117","https://openalex.org/W2039744784","https://openalex.org/W2043994556","https://openalex.org/W2046708576","https://openalex.org/W2051576033","https://openalex.org/W2051760916","https://openalex.org/W2056525414","https://openalex.org/W2060488177","https://openalex.org/W2066507340","https://openalex.org/W2069598312","https://openalex.org/W2070422796","https://openalex.org/W2074910566","https://openalex.org/W2077475465","https://openalex.org/W2085115067","https://openalex.org/W2091624650","https://openalex.org/W2091962716","https://openalex.org/W2099528329","https://openalex.org/W2102047788","https://openalex.org/W2103267125","https://openalex.org/W2117379817","https://openalex.org/W2119944195","https://openalex.org/W2124811236","https://openalex.org/W2134389003","https://openalex.org/W2150690655","https://openalex.org/W2153923972","https://openalex.org/W2952011241"],"related_works":["https://openalex.org/W2952125536","https://openalex.org/W2134495892","https://openalex.org/W7046844199","https://openalex.org/W2575521580","https://openalex.org/W4408227535","https://openalex.org/W7112843919","https://openalex.org/W4286500892","https://openalex.org/W2901955242","https://openalex.org/W7124500786","https://openalex.org/W4407616592"],"abstract_inverted_index":{"The":[0],"methanolic":[1],"extract":[2],"from":[3,40],"the":[4,41,64],"flowers":[5],"of":[6],"Punica":[7],"granatum":[8],"L.":[9],"(Punicaceae)":[10],"was":[11,38],"found":[12],"to":[13],"show":[14],"inhibitory":[15],"effect":[16],"on":[17],"tumor":[18],"necrosis":[19],"factor-alpha":[20],"(TNF-alpha,":[21],"1":[22],"ng/ml)-induced":[23],"cytotoxicity":[24,85],"in":[25,86],"L929":[26,87],"cells.":[27],"By":[28],"bioassay-guided":[29],"separation,":[30],"a":[31],"new":[32],"taraxastane-type":[33],"triterpene,":[34],"punicanolic":[35],"acid":[36,68,71],"(1),":[37],"isolated":[39],"active":[42],"fraction":[43],"(ethyl":[44],"acetate-soluble":[45],"fraction)":[46],"together":[47],"with":[48],"four":[49],"triterpenes":[50],"(2--5),":[51],"two":[52,57],"galloyl":[53],"glucoses":[54],"(6,":[55],"7),":[56],"flavones":[58],"(8,":[59],"9),":[60],"and":[61,79],"beta-sitosterol.":[62],"Among":[63],"constituents,":[65],"1,":[66],"oleanolic":[67],"(2),":[69],"maslinic":[70],"(4),":[72],"1,2,6-tri-O-galloyl":[73],"beta-D-glucopyranoside":[74,77],"(6),":[75],"1,2-di-O-galloyl-4,6-O-(S)-hexahydroxydiphenoyl":[76],"(7),":[78],"luteolin":[80],"(8)":[81],"significantly":[82],"inhibited":[83],"TNF-alpha-induced":[84],"cells":[88],"at":[89],"30":[90],"microM.":[91]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}