{"id":"https://openalex.org/W2075706291","doi":"https://doi.org/10.1016/s0003-4975(98)00092-7","title":"Temporal Relation of ATP-Sensitive Potassium-Channel Activation and Contractility Before Cardioplegia","display_name":"Temporal Relation of ATP-Sensitive Potassium-Channel Activation and Contractility Before Cardioplegia","publication_year":1998,"publication_date":"1998-04-01","ids":{"openalex":"https://openalex.org/W2075706291","doi":"https://doi.org/10.1016/s0003-4975(98)00092-7","mag":"2075706291","pmid":"https://pubmed.ncbi.nlm.nih.gov/9564931"},"language":"en","primary_location":{"id":"doi:10.1016/s0003-4975(98)00092-7","doi":"https://doi.org/10.1016/s0003-4975(98)00092-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0003-4975(98)00092-7","pdf_url":"http://www.annalsthoracicsurgery.org/article/S0003497598000927/pdf","source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.annalsthoracicsurgery.org/article/S0003497598000927/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061323680","display_name":"Latha Hebbar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Latha Hebbar","raw_affiliation_strings":["Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston 29425-2207, USA","Department of Anesthesia and Perioperative Medicine, Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston 29425-2207, USA","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Department of Anesthesia and Perioperative Medicine, Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042619903","display_name":"Ward V. Houck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ward V. Houck","raw_affiliation_strings":["Department of Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019414083","display_name":"James L. Zellner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James L. Zellner","raw_affiliation_strings":["Department of Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108211934","display_name":"B. Hugh Dorman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.Hugh Dorman","raw_affiliation_strings":["Department of Anesthesia and Perioperative Medicine, Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesia and Perioperative Medicine, Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041498326","display_name":"Francis G. Spinale","orcid":"https://orcid.org/0000-0003-0529-5605","observed_orcids":["https://orcid.org/0000-0003-0529-5605"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Francis G. Spinale","raw_affiliation_strings":["Department of Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA","institution_ids":["https://openalex.org/I153297377"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5041498326"],"corresponding_institution_ids":["https://openalex.org/I153297377"],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":0.2502,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.60965504,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"65","issue":"4","first_page":"1077","last_page":"1082"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/potassium-channel-openers","display_name":"potassium channel openers","score":0.9120000004768372},{"id":"https://openalex.org/keywords/aprikalim","display_name":"aprikalim","score":0.9589999914169312},{"id":"https://openalex.org/keywords/cardioplegic-arrest","display_name":"cardioplegic arrest","score":0.8650000095367432},{"id":"https://openalex.org/keywords/cardioprotection","display_name":"cardioprotection","score":0.7319999933242798},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.7170000076293945},{"id":"https://openalex.org/keywords/rewarming","display_name":"rewarming","score":0.574999988079071},{"id":"https://openalex.org/keywords/treatment-timing","display_name":"treatment timing","score":0.5389999747276306},{"id":"https://openalex.org/keywords/cardiac-surgery","display_name":"cardiac surgery","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C39133596","wikidata":"https://www.wikidata.org/wiki/Q5165683","display_name":"Contractility","level":2,"score":0.837149977684021},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8037635087966919},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.615828812122345},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5704813599586487},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5027482509613037},{"id":"https://openalex.org/C2776894844","wikidata":"https://www.wikidata.org/wiki/Q1197437","display_name":"Fissipedia","level":2,"score":0.46112507581710815},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4420100450515747},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.42949995398521423},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09162008762359619},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077331","descriptor_name":"Ringer's Solution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000318","descriptor_name":"Adrenergic beta-Agonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002314","descriptor_name":"Cardioplegic Solutions","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002316","descriptor_name":"Cardiotonic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005905","descriptor_name":"Glyburide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006324","descriptor_name":"Heart Arrest, Induced","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007036","descriptor_name":"Hypothermia, Induced","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007545","descriptor_name":"Isoproterenol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007552","descriptor_name":"Isotonic Solutions","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009200","descriptor_name":"Myocardial Contraction","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D010847","descriptor_name":"Picolines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011714","descriptor_name":"Pyrans","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015425","descriptor_name":"Myocardial Reperfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017694","descriptor_name":"Rewarming","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018715","descriptor_name":"Microscopy, Video","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026902","descriptor_name":"Potassium Channel Blockers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0003-4975(98)00092-7","doi":"https://doi.org/10.1016/s0003-4975(98)00092-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0003-4975(98)00092-7","pdf_url":"http://www.annalsthoracicsurgery.org/article/S0003497598000927/pdf","source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},{"id":"pmid:9564931","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9564931","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of thoracic surgery","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1016/s0003-4975(98)00092-7","doi":"https://doi.org/10.1016/s0003-4975(98)00092-7","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0003-4975(98)00092-7","pdf_url":"http://www.annalsthoracicsurgery.org/article/S0003497598000927/pdf","source":{"id":"https://openalex.org/S144860794","display_name":"The Annals of Thoracic Surgery","issn_l":"0003-4975","issn":["0003-4975","1552-6259"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Annals of Thoracic Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8063999825","display_name":"STRUCTURAL REMODELING IN CARDIOMYOPATHY AND RECOVERY","funder_award_id":"R29HL045024","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2075706291.pdf","grobid_xml":"https://content.openalex.org/works/W2075706291.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1565733551","https://openalex.org/W1963715537","https://openalex.org/W1969978734","https://openalex.org/W1981762076","https://openalex.org/W1986874340","https://openalex.org/W1987946315","https://openalex.org/W1991149230","https://openalex.org/W2002484365","https://openalex.org/W2004355280","https://openalex.org/W2006549990","https://openalex.org/W2030809229","https://openalex.org/W2046751422","https://openalex.org/W2049252096","https://openalex.org/W2062294237","https://openalex.org/W2071425476","https://openalex.org/W2082280658","https://openalex.org/W2083275191","https://openalex.org/W2093104453","https://openalex.org/W2129167542","https://openalex.org/W2136556999","https://openalex.org/W2164183838","https://openalex.org/W2396806720","https://openalex.org/W2399329612","https://openalex.org/W2416563191","https://openalex.org/W2430383105","https://openalex.org/W3145568296"],"related_works":["https://openalex.org/W2418855165","https://openalex.org/W2055055427","https://openalex.org/W2425626448","https://openalex.org/W2059460327","https://openalex.org/W2087869009","https://openalex.org/W1565733551","https://openalex.org/W2163246034","https://openalex.org/W2093104453","https://openalex.org/W2044819045","https://openalex.org/W2046751422"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}