{"id":"https://openalex.org/W2075650331","doi":"https://doi.org/10.1111/j.1348-0421.1988.tb01402.x","title":"Effect of Temperature on Antibacterial Activity of Lidocaine to Staphylococcus aureus and Pseudomonas aeruginosa","display_name":"Effect of Temperature on Antibacterial Activity of Lidocaine to Staphylococcus aureus and Pseudomonas aeruginosa","publication_year":1988,"publication_date":"1988-04-01","ids":{"openalex":"https://openalex.org/W2075650331","doi":"https://doi.org/10.1111/j.1348-0421.1988.tb01402.x","mag":"2075650331","pmid":"https://pubmed.ncbi.nlm.nih.gov/3134598"},"language":"en","primary_location":{"id":"doi:10.1111/j.1348-0421.1988.tb01402.x","doi":"https://doi.org/10.1111/j.1348-0421.1988.tb01402.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1348-0421.1988.tb01402.x","pdf_url":null,"source":{"id":"https://openalex.org/S149171590","display_name":"Microbiology and Immunology","issn_l":"0385-5600","issn":["0385-5600","1348-0421"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology and Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080229657","display_name":"Yoshiharu Taki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiharu Taki","raw_affiliation_strings":["Department of Orthopaedics The Jikei University School of Medicine Minato\u2010ku Tokyo 105"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics The Jikei University School of Medicine Minato\u2010ku Tokyo 105","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Keiko Seki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiko Seki","raw_affiliation_strings":["Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014217114","display_name":"Hajime Ikigai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hajime Ikigai","raw_affiliation_strings":["Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025429263","display_name":"Shoko Nishihara","orcid":"https://orcid.org/0000-0002-1668-2603","observed_orcids":["https://orcid.org/0000-0002-1668-2603"]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shoko Nishihara","raw_affiliation_strings":["Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hiroshi Ueno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Ueno","raw_affiliation_strings":["Department of Orthopaedics The Jikei University School of Medicine  Minato\u2010ku Tokyo 105"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics The Jikei University School of Medicine  Minato\u2010ku Tokyo 105","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113586834","display_name":"Kagehisa Murota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kagehisa Murota","raw_affiliation_strings":["Department of Orthopaedics The Jikei University School of Medicine  Minato\u2010ku Tokyo 105"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics The Jikei University School of Medicine  Minato\u2010ku Tokyo 105","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109962356","display_name":"Sh\u014dgo Masuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shogo Masuda","raw_affiliation_strings":["Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology The Jikei University School of Medicine  Minato\u2010ku Tokyo 105","institution_ids":["https://openalex.org/I115498069"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I115498069"],"apc_list":{"value":2750,"currency":"USD","value_usd":2750},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.20350109,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"32","issue":"4","first_page":"429","last_page":"434"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lidocaine","display_name":"lidocaine","score":1.0},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.8529999852180481},{"id":"https://openalex.org/keywords/temperature-effects","display_name":"temperature effects","score":0.6769999861717224},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":1.0},{"id":"https://openalex.org/keywords/local-anesthetics","display_name":"local anesthetics","score":0.6700000166893005},{"id":"https://openalex.org/keywords/bacterial-susceptibility","display_name":"bacterial susceptibility","score":0.5699999928474426}],"concepts":[{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.871361255645752},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.8461095690727234},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.733884334564209},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5828266143798828},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.5143111944198608},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.24440035223960876},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004352","descriptor_name":"Drug Resistance, Microbial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008012","descriptor_name":"Lidocaine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1348-0421.1988.tb01402.x","doi":"https://doi.org/10.1111/j.1348-0421.1988.tb01402.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1348-0421.1988.tb01402.x","pdf_url":null,"source":{"id":"https://openalex.org/S149171590","display_name":"Microbiology and Immunology","issn_l":"0385-5600","issn":["0385-5600","1348-0421"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology and Immunology","raw_type":"journal-article"},{"id":"pmid:3134598","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3134598","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbiology and immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1598643903","https://openalex.org/W2054079326","https://openalex.org/W2077037415","https://openalex.org/W2104570804","https://openalex.org/W2271112592","https://openalex.org/W2401339137"],"related_works":["https://openalex.org/W4249712983","https://openalex.org/W2146919056","https://openalex.org/W2074562407","https://openalex.org/W2007025525","https://openalex.org/W2001667184","https://openalex.org/W2946347697","https://openalex.org/W2748930222","https://openalex.org/W4233044692","https://openalex.org/W2330762524","https://openalex.org/W1968969392"],"abstract_inverted_index":{"The":[0,126],"effect":[1,132],"of":[2,8,39,50,77,84,109,129,137],"temperature":[3],"on":[4,133],"the":[5,36,63,130,134],"antibacterial":[6,37,55,72,89,135],"activity":[7,38,73,136],"lidocaine":[9,40,78,122,138],"to":[10,41,56,74,90,117,121],"Staphylococcus":[11],"aureus":[12,26,43,58,76,92],"and":[13,31],"Pseudomonas":[14],"aeruginosa":[15,103,114],"was":[16,44,53,79,87,115,139],"investigated":[17],"in":[18,47,81,107,141],"vitro.":[19],"At":[20],"10":[21],"C":[22,68],"at":[23,59,66,94],"which":[24,52,86],"S.":[25,42,57,75,91,110,124],"organisms":[27,93,104],"do":[28],"not":[29,45,88],"grow":[30],"might":[32],"be":[33,118],"metabolically":[34],"inactive,":[35],"observed":[46,80],"a":[48,69,82],"concentration":[49,83],"1%,":[51],"quite":[54],"37":[60,95],"C.":[61,96],"On":[62],"other":[64],"hand,":[65],"40":[67],"conspicuously":[70],"increased":[71],"0.25%":[85],"Similar":[97],"results":[98],"were":[99,105],"obtained":[100],"when":[101],"P.":[102,113],"examined":[106],"place":[108],"aureus,":[111],"although":[112],"found":[116],"less":[119],"susceptible":[120],"than":[123],"aureus.":[125],"clinical":[127],"significance":[128],"thermal":[131],"discussed":[140],"brief.":[142]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}