{"id":"https://openalex.org/W2074889960","doi":"https://doi.org/10.1093/oxfordjournals.jjco.a023181","title":"AFP-producing Squamous Cell Carcinoma of the Lung in an Adolescent","display_name":"AFP-producing Squamous Cell Carcinoma of the Lung in an Adolescent","publication_year":1996,"publication_date":"1996-04-01","ids":{"openalex":"https://openalex.org/W2074889960","doi":"https://doi.org/10.1093/oxfordjournals.jjco.a023181","mag":"2074889960","pmid":"https://pubmed.ncbi.nlm.nih.gov/8609692"},"language":"en","primary_location":{"id":"doi:10.1093/oxfordjournals.jjco.a023181","doi":"https://doi.org/10.1093/oxfordjournals.jjco.a023181","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.jjco.a023181","pdf_url":null,"source":{"id":"https://openalex.org/S149902429","display_name":"Japanese Journal of Clinical Oncology","issn_l":"0368-2811","issn":["0368-2811","1465-3621"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060646340","display_name":"Hisao Asamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087348","display_name":"National Cancer Centre Japan","ror":"https://ror.org/0025ww868","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348"]},{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"H. Asamura","raw_affiliation_strings":["Division of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan","Division of Thoracic Surgery, National Cancer Center HospitalTokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405285273"]},{"raw_affiliation_string":"Division of Thoracic Surgery, National Cancer Center HospitalTokyo","institution_ids":["https://openalex.org/I4210087348"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H. Nakayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087348","display_name":"National Cancer Centre Japan","ror":"https://ror.org/0025ww868","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348"]},{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Nakayama","raw_affiliation_strings":["Division of Thoracic Surgery, National Cancer Center Hospital Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Thoracic Surgery, National Cancer Center Hospital Tokyo","institution_ids":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112785468","display_name":"Haruhiko Kondo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087348","display_name":"National Cancer Centre Japan","ror":"https://ror.org/0025ww868","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348"]},{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Kondo","raw_affiliation_strings":["Division of Thoracic Surgery, National Cancer Center Hospital Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Thoracic Surgery, National Cancer Center Hospital Tokyo","institution_ids":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111373903","display_name":"Ryosuke Tsuchiya","orcid":"https://orcid.org/0000-0001-7407-3665","observed_orcids":["https://orcid.org/0000-0001-7407-3665"]},"institutions":[{"id":"https://openalex.org/I4210087348","display_name":"National Cancer Centre Japan","ror":"https://ror.org/0025ww868","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348"]},{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"R. Tsuchiya","raw_affiliation_strings":["Division of Thoracic Surgery, National Cancer Center Hospital Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Thoracic Surgery, National Cancer Center Hospital Tokyo","institution_ids":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108132596","display_name":"Ryusuke Ono","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087348","display_name":"National Cancer Centre Japan","ror":"https://ror.org/0025ww868","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348"]},{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"R. Ono","raw_affiliation_strings":["Division of Thoracic Surgery, National Cancer Center Hospital Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Thoracic Surgery, National Cancer Center Hospital Tokyo","institution_ids":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051611223","display_name":"Masayuki Noguchi","orcid":"https://orcid.org/0000-0002-8767-4707","observed_orcids":["https://orcid.org/0000-0002-8767-4707"]},"institutions":[{"id":"https://openalex.org/I4210087348","display_name":"National Cancer Centre Japan","ror":"https://ror.org/0025ww868","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348"]},{"id":"https://openalex.org/I4405287541","display_name":"National Cancer Center Research Institute","ror":"https://ror.org/05fd4mq57","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405287541"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M. Noguchi","raw_affiliation_strings":["Pathology Division, National Cancer Center Research Institute Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology Division, National Cancer Center Research Institute Tokyo","institution_ids":["https://openalex.org/I4210087348","https://openalex.org/I4405287541"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064339671","display_name":"Hitoshi Yoda","orcid":"https://orcid.org/0009-0005-6465-9327","observed_orcids":["https://orcid.org/0009-0005-6465-9327"]},"institutions":[{"id":"https://openalex.org/I4210137409","display_name":"National Hospital Organization","ror":"https://ror.org/03ntccx93","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Yoda","raw_affiliation_strings":["National Toshin Hospital Nagano","National Hospital Organization, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Toshin Hospital Nagano","institution_ids":[]},{"raw_affiliation_string":"National Hospital Organization, Japan","institution_ids":["https://openalex.org/I4210137409"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112178751","display_name":"Takashi Naruke","orcid":"https://orcid.org/0009-0007-8243-082X","observed_orcids":["https://orcid.org/0009-0007-8243-082X"]},"institutions":[{"id":"https://openalex.org/I4210087348","display_name":"National Cancer Centre Japan","ror":"https://ror.org/0025ww868","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348"]},{"id":"https://openalex.org/I4405285273","display_name":"National Cancer Center Hospital","ror":"https://ror.org/053hhpd64","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Naruke","raw_affiliation_strings":["Division of Thoracic Surgery, National Cancer Center Hospital Tokyo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Thoracic Surgery, National Cancer Center Hospital Tokyo","institution_ids":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5060646340"],"corresponding_institution_ids":["https://openalex.org/I4210087348","https://openalex.org/I4405285273"],"apc_list":{"value":3604,"currency":"USD","value_usd":3604},"apc_paid":null,"fwci":0.9959,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.76882818,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"26","issue":"2","first_page":"103","last_page":"106"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12992","display_name":"Metastasis and carcinoma case studies","score":0.7728999853134155,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12992","display_name":"Metastasis and carcinoma case studies","score":0.7728999853134155,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.1679999977350235,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.03060000017285347,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/squamous-cell-carcinoma","display_name":"squamous cell carcinoma","score":0.7950000166893005},{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":0.9509999752044678},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.7789999842643738},{"id":"https://openalex.org/keywords/alpha-fetoprotein","display_name":"alpha-fetoprotein","score":0.9419999718666077},{"id":"https://openalex.org/keywords/hypercalcemia","display_name":"hypercalcemia","score":0.7689999938011169},{"id":"https://openalex.org/keywords/pneumonectomy","display_name":"pneumonectomy","score":0.7929999828338623},{"id":"https://openalex.org/keywords/extracorporeal-circulation","display_name":"extracorporeal circulation","score":0.9350000023841858},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9799425601959229},{"id":"https://openalex.org/C2777589429","wikidata":"https://www.wikidata.org/wiki/Q46565","display_name":"Pneumonectomy","level":3,"score":0.6875050067901611},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.589970588684082},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.5745777487754822},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5443860292434692},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.49519267678260803},{"id":"https://openalex.org/C2994232697","wikidata":"https://www.wikidata.org/wiki/Q1115882","display_name":"Extracorporeal circulation","level":2,"score":0.45650702714920044},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4418962001800537},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.4326953589916229},{"id":"https://openalex.org/C2778078201","wikidata":"https://www.wikidata.org/wiki/Q2964004","display_name":"Lung cancer surgery","level":3,"score":0.4110392928123474},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2889249920845032}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000509","descriptor_name":"alpha-Fetoproteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/oxfordjournals.jjco.a023181","doi":"https://doi.org/10.1093/oxfordjournals.jjco.a023181","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oxfordjournals.jjco.a023181","pdf_url":null,"source":{"id":"https://openalex.org/S149902429","display_name":"Japanese Journal of Clinical Oncology","issn_l":"0368-2811","issn":["0368-2811","1465-3621"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmid:8609692","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8609692","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japanese journal of clinical oncology","raw_type":"Case Reports"},{"id":"pmh:oai:open-archive.highwire.org:jjco:26/2/103","doi":null,"is_oa":false,"landing_page_url":"http://jjco.oxfordjournals.org/cgi/content/short/26/2/103","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W172635172","https://openalex.org/W1559616885","https://openalex.org/W1975730940","https://openalex.org/W2045888209","https://openalex.org/W2057661852","https://openalex.org/W2065618503","https://openalex.org/W2115111939","https://openalex.org/W2154746489","https://openalex.org/W2165476104","https://openalex.org/W2344591136"],"related_works":["https://openalex.org/W2061901901","https://openalex.org/W4210359560","https://openalex.org/W2313862495","https://openalex.org/W2328357484","https://openalex.org/W7096027477","https://openalex.org/W2333593797","https://openalex.org/W2551341958","https://openalex.org/W1977976663","https://openalex.org/W2324150108","https://openalex.org/W2937825996"],"abstract_inverted_index":{"We":[0,47],"report":[1],"a":[2,9,83],"case":[3],"of":[4,15,44,54,58,101,111],"primary":[5],"lung":[6],"cancer":[7],"in":[8,69],"16-year-old":[10],"boy.":[11],"A":[12],"histologic":[13],"diagnosis":[14],"squamous":[16],"cell":[17],"carcinoma":[18],"was":[19,31,98,114,118],"made":[20],"by":[21],"bronchoscopic":[22],"biopsy":[23],"before":[24],"surgery.":[25],"The":[26,123],"serum":[27],"alphafetoprotein":[28],"(AFP)":[29],"level":[30,78],"markedly":[32],"elevated":[33],"at":[34],"193":[35],"ng/dl.":[36],"Preoperative":[37],"and":[38,86,103,116],"postoperative":[39,93,108,129],"evaluation":[40],"revealed":[41],"no":[42],"evidence":[43],"scrotal":[45],"mass.":[46],"performed":[48],"right":[49],"pneumonectomy":[50],"with":[51],"combined":[52],"resection":[53],"the":[55,59,66,70,76,91,96,106,127],"invaded":[56],"portion":[57],"left":[60],"atrium":[61],"under":[62],"extracorporeal":[63],"circulation.":[64],"Despite":[65],"rapid":[67],"improvement":[68],"patient's":[71],"general":[72],"condition":[73],"after":[74],"surgery,":[75],"AFP":[77],"continued":[79],"to":[80,120],"increase":[81],"without":[82],"transient":[84],"decrease":[85],"reached":[87],"3160":[88],"ng/ml":[89],"on":[90,105,126],"23rd":[92],"day.":[94,130],"When":[95],"patient":[97,124],"readmitted":[99],"because":[100],"dyspnea":[102],"headache":[104],"36th":[107],"day,":[109],"hypercalcemia":[110],"13.9":[112],"mg/dl":[113],"noted,":[115],"this":[117],"resistant":[119],"subsequent":[121],"treatment.":[122],"died":[125],"46th":[128]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}