{"id":"https://openalex.org/W2074054536","doi":"https://doi.org/10.1016/j.placenta.2008.11.004","title":"Tolerance of Human Placental Tissue to Severe Hypoxia and Its Relevance for Dual Ex Vivo Perfusion","display_name":"Tolerance of Human Placental Tissue to Severe Hypoxia and Its Relevance for Dual Ex Vivo Perfusion","publication_year":2008,"publication_date":"2008-12-07","ids":{"openalex":"https://openalex.org/W2074054536","doi":"https://doi.org/10.1016/j.placenta.2008.11.004","mag":"2074054536","pmid":"https://pubmed.ncbi.nlm.nih.gov/19064287"},"language":"en","primary_location":{"id":"doi:10.1016/j.placenta.2008.11.004","doi":"https://doi.org/10.1016/j.placenta.2008.11.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.placenta.2008.11.004","pdf_url":null,"source":{"id":"https://openalex.org/S171513543","display_name":"Placenta","issn_l":"0143-4004","issn":["0143-4004","1532-3102"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058125413","display_name":"H. Schneider","orcid":"https://orcid.org/0009-0008-9427-1229","observed_orcids":["https://orcid.org/0009-0008-9427-1229"]},"institutions":[{"id":"https://openalex.org/I2801112126","display_name":"University Hospital of Bern","ror":"https://ror.org/01q9sj412","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2801112126"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"H. Schneider","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Universit\u00e4ts-Frauenklinik, Insel Spital, Berne, Switzerland. henning.schneider@hispeed.ch","Department of Obstetrics and Gynecology, Universit\u00e4ts-Frauenklinik, Insel Spital, Berne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Universit\u00e4ts-Frauenklinik, Insel Spital, Berne, Switzerland. henning.schneider@hispeed.ch","institution_ids":["https://openalex.org/I2801112126"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Universit\u00e4ts-Frauenklinik, Insel Spital, Berne, Switzerland","institution_ids":["https://openalex.org/I2801112126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5058125413"],"corresponding_institution_ids":["https://openalex.org/I2801112126"],"apc_list":{"value":3720,"currency":"USD","value_usd":3720},"apc_paid":null,"fwci":0.523,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.46666667,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"30","issue":null,"first_page":"71","last_page":"76"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.8988999724388123,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.8988999724388123,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.05180000141263008,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-placenta","display_name":"human placenta","score":0.7850000262260437},{"id":"https://openalex.org/keywords/hypoxia-tolerance","display_name":"hypoxia tolerance","score":0.9269999861717224},{"id":"https://openalex.org/keywords/placental-cotyledons","display_name":"placental cotyledons","score":0.9440000057220459},{"id":"https://openalex.org/keywords/placental-villi","display_name":"placental villi","score":0.6029999852180481},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.6650000214576721},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.9810000061988831},{"id":"https://openalex.org/keywords/placental-metabolism","display_name":"placental metabolism","score":0.5590000152587891},{"id":"https://openalex.org/keywords/fetal-hypoxia","display_name":"fetal hypoxia","score":0.39899998903274536}],"concepts":[{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.7472978830337524},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.7080895900726318},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6378209590911865},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.6045489311218262},{"id":"https://openalex.org/C2993207723","wikidata":"https://www.wikidata.org/wiki/Q4927803","display_name":"Oxygen tension","level":3,"score":0.5749903321266174},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.5688703060150146},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.5102500915527344},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.38633719086647034},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3824959397315979},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35591065883636475},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.3455524444580078},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.34093695878982544},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.32457149028778076},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18066346645355225},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1474400758743286},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.13946539163589478},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001481","descriptor_name":"Basal Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006605","descriptor_name":"Hibernation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015427","descriptor_name":"Reperfusion Injury","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.placenta.2008.11.004","doi":"https://doi.org/10.1016/j.placenta.2008.11.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.placenta.2008.11.004","pdf_url":null,"source":{"id":"https://openalex.org/S171513543","display_name":"Placenta","issn_l":"0143-4004","issn":["0143-4004","1532-3102"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"journal-article"},{"id":"pmid:19064287","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19064287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Placenta","raw_type":"Journal Article"},{"id":"pmh:oai:boris.unibe.ch:27874","doi":null,"is_oa":false,"landing_page_url":"https://boris.unibe.ch/27874/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401086","display_name":"Bern Open Repository and Information System (University of Bern)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118564535","host_organization_name":"University of Bern","host_organization_lineage":["https://openalex.org/I118564535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Schneider, H (2009). Tolerance of human placental tissue to severe hypoxia and its relevance for dual ex vivo perfusion. Placenta, 30 Suppl A, S71-S76. Amsterdam: Elsevier 10.1016/j.placenta.2008.11.004 <http://dx.doi.org/10.1016/j.placenta.2008.11.004>","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W564179495","https://openalex.org/W597378496","https://openalex.org/W1509389829","https://openalex.org/W1537220258","https://openalex.org/W1538482178","https://openalex.org/W1552761384","https://openalex.org/W1562852527","https://openalex.org/W1777530915","https://openalex.org/W1855117407","https://openalex.org/W1971149837","https://openalex.org/W1973175580","https://openalex.org/W1990335913","https://openalex.org/W2002825609","https://openalex.org/W2008037823","https://openalex.org/W2015849090","https://openalex.org/W2016650100","https://openalex.org/W2019860345","https://openalex.org/W2024996129","https://openalex.org/W2041277679","https://openalex.org/W2045899137","https://openalex.org/W2046348353","https://openalex.org/W2052788551","https://openalex.org/W2055785937","https://openalex.org/W2061865477","https://openalex.org/W2064976764","https://openalex.org/W2078594307","https://openalex.org/W2081685662","https://openalex.org/W2087324157","https://openalex.org/W2090506996","https://openalex.org/W2091352702","https://openalex.org/W2092101649","https://openalex.org/W2092454649","https://openalex.org/W2100288303","https://openalex.org/W2110295318","https://openalex.org/W2124047731","https://openalex.org/W2135603076","https://openalex.org/W2137248860","https://openalex.org/W2145219202","https://openalex.org/W2172199758","https://openalex.org/W2326412161","https://openalex.org/W2404688012","https://openalex.org/W2586831009","https://openalex.org/W2619365542","https://openalex.org/W2978126214"],"related_works":["https://openalex.org/W2158472583","https://openalex.org/W2019153639","https://openalex.org/W3199650503","https://openalex.org/W2052788551","https://openalex.org/W2090310456","https://openalex.org/W2082713987","https://openalex.org/W2168772628","https://openalex.org/W2062489041","https://openalex.org/W1481458584","https://openalex.org/W4408833706"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}