{"id":"https://openalex.org/W2074038463","doi":"https://doi.org/10.1083/jcb.200105102","title":"Abelson kinase regulates epithelial morphogenesis in Drosophila","display_name":"Abelson kinase regulates epithelial morphogenesis in Drosophila","publication_year":2001,"publication_date":"2001-12-24","ids":{"openalex":"https://openalex.org/W2074038463","doi":"https://doi.org/10.1083/jcb.200105102","mag":"2074038463","pmid":"https://pubmed.ncbi.nlm.nih.gov/11756472","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2199330"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.200105102","doi":"https://doi.org/10.1083/jcb.200105102","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.200105102","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2199330","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090867256","display_name":"Elizabeth E. Grevengoed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth E. Grevengoed","raw_affiliation_strings":["1Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027891362","display_name":"Joseph Loureiro","orcid":"https://orcid.org/0000-0001-7222-9160","observed_orcids":["https://orcid.org/0000-0001-7222-9160"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph J. Loureiro","raw_affiliation_strings":["2Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016976508","display_name":"Traci L. Jesse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Traci L. Jesse","raw_affiliation_strings":["3Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068906620","display_name":"Mark A. Peifer","orcid":"https://orcid.org/0000-0003-1412-3987","observed_orcids":["https://orcid.org/0000-0003-1412-3987"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark Peifer","raw_affiliation_strings":["1Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","2Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","3Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"2Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"3Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068906620"],"corresponding_institution_ids":["https://openalex.org/I114027177","https://openalex.org/I4390039329"],"apc_list":null,"apc_paid":null,"fwci":2.7114,"has_fulltext":true,"cited_by_count":143,"citation_normalized_percentile":{"value":0.89102631,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"155","issue":"7","first_page":"1185","last_page":"1198"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.5396000146865845,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.5396000146865845,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.2809999883174896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.09390000253915787,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abelson-kinase","display_name":"Abelson kinase","score":0.9810000061988831},{"id":"https://openalex.org/keywords/epithelial-morphogenesis","display_name":"epithelial morphogenesis","score":0.9139999747276306},{"id":"https://openalex.org/keywords/dorsal-closure","display_name":"dorsal closure","score":0.9070000052452087},{"id":"https://openalex.org/keywords/enabled","display_name":"Enabled","score":0.7749999761581421},{"id":"https://openalex.org/keywords/actin-dynamics","display_name":"actin dynamics","score":0.8510000109672546},{"id":"https://openalex.org/keywords/adherens-junctions","display_name":"adherens junctions","score":0.9959999918937683},{"id":"https://openalex.org/keywords/armadillos","display_name":"armadillos","score":0.9800000190734863},{"id":"https://openalex.org/keywords/de-cadherin","display_name":"DE-cadherin","score":0.9549999833106995},{"id":"https://openalex.org/keywords/shotguns","display_name":"shotguns","score":0.7649999856948853},{"id":"https://openalex.org/keywords/alpha-catenin","display_name":"alpha-catenin","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.8109999895095825},{"id":"https://openalex.org/keywords/cell-morphology-changes","display_name":"cell shape changes","score":0.8220000267028809},{"id":"https://openalex.org/keywords/drosophila-embryo","display_name":"Drosophila embryo","score":0.8240000009536743},{"id":"https://openalex.org/keywords/non-receptor-tyrosine-kinase","display_name":"non-receptor tyrosine kinase","score":0.8700000047683716}],"concepts":[{"id":"https://openalex.org/C201508349","wikidata":"https://www.wikidata.org/wiki/Q45173","display_name":"Adherens junction","level":4,"score":0.9111422896385193},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8797065019607544},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.8225485682487488},{"id":"https://openalex.org/C125418893","wikidata":"https://www.wikidata.org/wiki/Q587961","display_name":"ABL","level":4,"score":0.7443228960037231},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.7154346704483032},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.44681596755981445},{"id":"https://openalex.org/C49353375","wikidata":"https://www.wikidata.org/wiki/Q189100","display_name":"Cell polarity","level":3,"score":0.42342519760131836},{"id":"https://openalex.org/C2780157343","wikidata":"https://www.wikidata.org/wiki/Q104840543","display_name":"Armadillo","level":2,"score":0.4223410487174988},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.4178531765937805},{"id":"https://openalex.org/C149402561","wikidata":"https://www.wikidata.org/wiki/Q24776048","display_name":"Cadherin","level":3,"score":0.41144317388534546},{"id":"https://openalex.org/C42362537","wikidata":"https://www.wikidata.org/wiki/Q87099740","display_name":"Tyrosine kinase","level":3,"score":0.27714061737060547},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22721922397613525},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.2178966999053955},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.1673946976661682},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08368262648582458}],"mesh":[{"descriptor_ui":"D000097905","descriptor_name":"Roundabout Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009424","descriptor_name":"Nervous System Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011971","descriptor_name":"Receptors, Immunologic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015723","descriptor_name":"Gene Library","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016475","descriptor_name":"3T3 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020662","descriptor_name":"Guanine Nucleotide Exchange Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020690","descriptor_name":"GTPase-Activating Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064067","descriptor_name":"Rho Guanine Nucleotide Exchange Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1083/jcb.200105102","doi":"https://doi.org/10.1083/jcb.200105102","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.200105102","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Cell Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2199330","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2199330","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmid:11756472","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11756472","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Journal Article"},{"id":"pmh:cdr.lib.unc.edu:1r66j699n","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.17615/8pcz-6038","pdf_url":"https://cdr.lib.unc.edu/downloads/3b591g39t","source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Asian Journal of Cell Biology, 155(7)","raw_type":"Article"},{"id":"doi:10.17615/8pcz-6038","doi":"https://doi.org/10.17615/8pcz-6038","is_oa":true,"landing_page_url":"https://doi.org/10.17615/8pcz-6038","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2199330","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2199330","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3757727673","display_name":"NRSA in Genetics","funder_award_id":"T32GM007092","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4339777089","display_name":"Integrated Training in Cancer Model Systems","funder_award_id":"T32CA009156","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6402396074","display_name":null,"funder_award_id":"5T3CA09156","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7424117460","display_name":"Nutritional Biochemistry and Epidemiology of Cancer","funder_award_id":"T32CA072319","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8097660198","display_name":"Cell adhesion, signal transduction and cytoskeletal regulation in Drosophila","funder_award_id":"R01GM047857","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8907275968","display_name":"ADHERENS JUNCTIONS SIGNALING PATHWAYS IN DROSOPHILA","funder_award_id":"F32GM020797","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W209719701","https://openalex.org/W1486645125","https://openalex.org/W1575878259","https://openalex.org/W1583757620","https://openalex.org/W1752721376","https://openalex.org/W1938204331","https://openalex.org/W1971766102","https://openalex.org/W1972659626","https://openalex.org/W1973131553","https://openalex.org/W1981566818","https://openalex.org/W1985656017","https://openalex.org/W2007766285","https://openalex.org/W2010087461","https://openalex.org/W2015114060","https://openalex.org/W2023915893","https://openalex.org/W2024782132","https://openalex.org/W2030945799","https://openalex.org/W2035771357","https://openalex.org/W2036479824","https://openalex.org/W2038403184","https://openalex.org/W2045860277","https://openalex.org/W2048184033","https://openalex.org/W2049706987","https://openalex.org/W2051281022","https://openalex.org/W2056862346","https://openalex.org/W2057974199","https://openalex.org/W2058416613","https://openalex.org/W2061761105","https://openalex.org/W2063076755","https://openalex.org/W2075278063","https://openalex.org/W2090217559","https://openalex.org/W2094735120","https://openalex.org/W2097276658","https://openalex.org/W2099022660","https://openalex.org/W2115093096","https://openalex.org/W2131283226","https://openalex.org/W2140795059","https://openalex.org/W2142526945","https://openalex.org/W2146934540","https://openalex.org/W2162245996","https://openalex.org/W2728956820"],"related_works":["https://openalex.org/W7098505171","https://openalex.org/W2152395437","https://openalex.org/W2470356093","https://openalex.org/W4298255965","https://openalex.org/W2504226354","https://openalex.org/W4252292400","https://openalex.org/W2004940993","https://openalex.org/W2099809076","https://openalex.org/W2038403184","https://openalex.org/W2045178384"],"abstract_inverted_index":{"Activation":[0],"of":[1,12,18,104,121,141,156,175,194],"the":[2,10,15,35,79,97,131,176],"nonreceptor":[3],"tyrosine":[4],"kinase":[5],"Abelson":[6],"(Abl)":[7],"contributes":[8],"to":[9,34,118],"development":[11,22],"leukemia,":[13],"but":[14],"complex":[16],"roles":[17],"Abl":[19,28,45,62,98,110,157,187],"in":[20,46,66,111,163,192],"normal":[21],"are":[23,144],"not":[24],"fully":[25],"understood.":[26],"Drosophila":[27,44],"links":[29],"neural":[30],"axon":[31],"guidance":[32],"receptors":[33],"cytoskeleton.":[36],"Here":[37],"we":[38,94],"report":[39],"a":[40,102],"novel":[41],"role":[42],"for":[43,53,149,186],"epithelial":[47,123,190],"cells,":[48,124],"where":[49],"it":[50,127],"is":[51,107],"critical":[52],"morphogenesis.":[54,112,138],"Embryos":[55],"completely":[56],"lacking":[57],"both":[58],"maternal":[59],"and":[60,74,125,160],"zygotic":[61],"die":[63],"with":[64,109,130],"defects":[65,81,140],"several":[67],"morphogenetic":[68],"processes":[69],"requiring":[70],"cell":[71,75,179],"shape":[72],"changes":[73],"migration.":[76],"We":[77,113,182],"describe":[78],"cellular":[80],"that":[82,96,115,126],"underlie":[83],"these":[84,195],"problems,":[85],"focusing":[86],"on":[87,172],"dorsal":[88],"closure":[89],"as":[90],"an":[91],"example.":[92],"Further,":[93],"show":[95],"target":[99],"Enabled":[100],"(Ena),":[101],"modulator":[103],"actin":[105],"dynamics,":[106],"involved":[108],"find":[114],"Ena":[116],"localizes":[117],"adherens":[119,132,164],"junctions":[120],"most":[122],"genetically":[128],"interacts":[129],"junction":[133],"protein":[134],"Armadillo":[135],"(Arm)":[136],"during":[137,189],"The":[139],"abl":[142],"mutants":[143],"strongly":[145],"enhanced":[146],"by":[147],"heterozygosity":[148],"shotgun,":[150],"which":[151],"encodes":[152],"DE-cadherin.":[153],"Finally,":[154],"loss":[155],"reduces":[158],"Arm":[159],"alpha-catenin":[161],"accumulation":[162],"junctions,":[165],"while":[166],"having":[167],"little":[168],"or":[169,178],"no":[170],"effect":[171],"other":[173],"components":[174],"cytoskeleton":[177],"polarity":[180],"machinery.":[181],"discuss":[183],"possible":[184],"models":[185],"function":[188],"morphogenesis":[191],"light":[193],"data.":[196]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}