{"id":"https://openalex.org/W2073974950","doi":"https://doi.org/10.2176/nmc.oa.2014-0287","title":"Endovascular Embolization of Brain Arteriovenous Malformations with Eudragit-E","display_name":"Endovascular Embolization of Brain Arteriovenous Malformations with Eudragit-E","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2073974950","doi":"https://doi.org/10.2176/nmc.oa.2014-0287","mag":"2073974950","pmid":"https://pubmed.ncbi.nlm.nih.gov/25739432","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4533335"},"language":"en","primary_location":{"id":"doi:10.2176/nmc.oa.2014-0287","doi":"https://doi.org/10.2176/nmc.oa.2014-0287","is_oa":true,"landing_page_url":"https://doi.org/10.2176/nmc.oa.2014-0287","pdf_url":"https://www.jstage.jst.go.jp/article/nmc/55/3/55_oa.2014-0287/_pdf","source":{"id":"https://openalex.org/S170822592","display_name":"Neurologia medico-chirurgica","issn_l":"0470-8105","issn":["0470-8105","1349-8029"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313358","host_organization_name":"Japan Neurological Society","host_organization_lineage":["https://openalex.org/P4310313358"],"host_organization_lineage_names":["Japan Neurological Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurologia medico-chirurgica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.jstage.jst.go.jp/article/nmc/55/3/55_oa.2014-0287/_pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037777677","display_name":"Goichiro Tamura","orcid":"https://orcid.org/0000-0003-1268-3673","observed_orcids":["https://orcid.org/0000-0003-1268-3673"]},"institutions":[{"id":"https://openalex.org/I4210096268","display_name":"National Hospital Organization Mito Medical Center","ror":"https://ror.org/00m9ydx43","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096268","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Goichiro TAMURA","raw_affiliation_strings":["Department of Neurosurgery, Mito Medical Center, National Health Organization"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mito Medical Center, National Health Organization","institution_ids":["https://openalex.org/I4210096268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080626582","display_name":"Noriyuki Kato","orcid":"https://orcid.org/0000-0001-7393-6019","observed_orcids":["https://orcid.org/0000-0001-7393-6019"]},"institutions":[{"id":"https://openalex.org/I4210096268","display_name":"National Hospital Organization Mito Medical Center","ror":"https://ror.org/00m9ydx43","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096268","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriyuki KATO","raw_affiliation_strings":["Department of Neurosurgery, Mito Medical Center, National Health Organization"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mito Medical Center, National Health Organization","institution_ids":["https://openalex.org/I4210096268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108685508","display_name":"Tomosato Yamazaki","orcid":"https://orcid.org/0000-0002-7020-3431","observed_orcids":["https://orcid.org/0000-0002-7020-3431"]},"institutions":[{"id":"https://openalex.org/I4210096268","display_name":"National Hospital Organization Mito Medical Center","ror":"https://ror.org/00m9ydx43","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096268","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomosato YAMAZAKI","raw_affiliation_strings":["Department of Neurosurgery, Mito Medical Center, National Health Organization"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mito Medical Center, National Health Organization","institution_ids":["https://openalex.org/I4210096268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053458239","display_name":"Yoshimitsu Akutsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096268","display_name":"National Hospital Organization Mito Medical Center","ror":"https://ror.org/00m9ydx43","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096268","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshimitsu AKUTSU","raw_affiliation_strings":["Department of Neurosurgery, Mito Medical Center, National Health Organization"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mito Medical Center, National Health Organization","institution_ids":["https://openalex.org/I4210096268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089710148","display_name":"Hisayuki Hosoo","orcid":"https://orcid.org/0000-0002-0392-6808","observed_orcids":["https://orcid.org/0000-0002-0392-6808"]},"institutions":[{"id":"https://openalex.org/I4210096268","display_name":"National Hospital Organization Mito Medical Center","ror":"https://ror.org/00m9ydx43","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096268","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisayuki HOSOO","raw_affiliation_strings":["Department of Neurosurgery, Mito Medical Center, National Health Organization"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mito Medical Center, National Health Organization","institution_ids":["https://openalex.org/I4210096268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110387787","display_name":"Hiromichi Kasuya","orcid":"https://orcid.org/0009-0002-5759-3241","observed_orcids":["https://orcid.org/0009-0002-5759-3241"]},"institutions":[{"id":"https://openalex.org/I4210096268","display_name":"National Hospital Organization Mito Medical Center","ror":"https://ror.org/00m9ydx43","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096268","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiromichi KASUYA","raw_affiliation_strings":["Department of Neurosurgery, Mito Medical Center, National Health Organization"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mito Medical Center, National Health Organization","institution_ids":["https://openalex.org/I4210096268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089403750","display_name":"Makoto Sonobe","orcid":"https://orcid.org/0000-0001-9747-7443","observed_orcids":["https://orcid.org/0000-0001-9747-7443"]},"institutions":[{"id":"https://openalex.org/I4210096268","display_name":"National Hospital Organization Mito Medical Center","ror":"https://ror.org/00m9ydx43","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210096268","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto SONOBE","raw_affiliation_strings":["Department of Neurosurgery, Mito Medical Center, National Health Organization"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mito Medical Center, National Health Organization","institution_ids":["https://openalex.org/I4210096268"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5037777677"],"corresponding_institution_ids":["https://openalex.org/I4210096268"],"apc_list":{"value":10000,"currency":"JPY","value_usd":75},"apc_paid":{"value":10000,"currency":"JPY","value_usd":75},"fwci":0.2042,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.51637235,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"55","issue":"3","first_page":"253","last_page":"260"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11402","display_name":"Vascular Malformations Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11402","display_name":"Vascular Malformations Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10980","display_name":"Vascular Malformations and Hemangiomas","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eudragit-e","display_name":"Eudragit E","score":0.9729999899864197},{"id":"https://openalex.org/keywords/brain-arteriovenous-malformations","display_name":"cerebral arteriovenous malformations","score":0.9259999990463257},{"id":"https://openalex.org/keywords/endovascular-embolization","display_name":"endovascular embolization","score":0.9559999704360962},{"id":"https://openalex.org/keywords/liquid-embolic-materials","display_name":"liquid embolic materials","score":0.8539999723434448},{"id":"https://openalex.org/keywords/embolization-complications","display_name":"embolization complications","score":0.5680000185966492},{"id":"https://openalex.org/keywords/cerebral-infarction","display_name":"cerebral infarction","score":0.9139999747276306},{"id":"https://openalex.org/keywords/intracerebral-hemorrhage","display_name":"intracerebral hemorrhage","score":0.8960000276565552},{"id":"https://openalex.org/keywords/spetzler-martin-grade","display_name":"Spetzler-Martin grade","score":0.8619999885559082},{"id":"https://openalex.org/keywords/stereotactic-radiosurgery","display_name":"stereotactic radiosurgery","score":0.8840000033378601}],"concepts":[{"id":"https://openalex.org/C2776035437","wikidata":"https://www.wikidata.org/wiki/Q1144114","display_name":"Embolization","level":2,"score":0.7318032383918762},{"id":"https://openalex.org/C2779603958","wikidata":"https://www.wikidata.org/wiki/Q1584110","display_name":"Arteriovenous malformation","level":2,"score":0.4692254960536957},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46445557475090027},{"id":"https://openalex.org/C3018386432","wikidata":"https://www.wikidata.org/wiki/Q426449","display_name":"Endovascular treatment","level":3,"score":0.43932002782821655},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3217993974685669},{"id":"https://openalex.org/C2776098176","wikidata":"https://www.wikidata.org/wiki/Q189389","display_name":"Aneurysm","level":2,"score":0.12282505631446838}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002538","descriptor_name":"Intracranial Arteriovenous Malformations","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002538","descriptor_name":"Intracranial Arteriovenous Malformations","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004621","descriptor_name":"Embolization, Therapeutic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008768","descriptor_name":"Methylmethacrylates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057510","descriptor_name":"Endovascular Procedures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.2176/nmc.oa.2014-0287","doi":"https://doi.org/10.2176/nmc.oa.2014-0287","is_oa":true,"landing_page_url":"https://doi.org/10.2176/nmc.oa.2014-0287","pdf_url":"https://www.jstage.jst.go.jp/article/nmc/55/3/55_oa.2014-0287/_pdf","source":{"id":"https://openalex.org/S170822592","display_name":"Neurologia medico-chirurgica","issn_l":"0470-8105","issn":["0470-8105","1349-8029"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313358","host_organization_name":"Japan Neurological Society","host_organization_lineage":["https://openalex.org/P4310313358"],"host_organization_lineage_names":["Japan Neurological Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurologia medico-chirurgica","raw_type":"journal-article"},{"id":"pmid:25739432","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25739432","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurologia medico-chirurgica","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:4533335","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4533335/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurol Med Chir (Tokyo)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.2176/nmc.oa.2014-0287","doi":"https://doi.org/10.2176/nmc.oa.2014-0287","is_oa":true,"landing_page_url":"https://doi.org/10.2176/nmc.oa.2014-0287","pdf_url":"https://www.jstage.jst.go.jp/article/nmc/55/3/55_oa.2014-0287/_pdf","source":{"id":"https://openalex.org/S170822592","display_name":"Neurologia medico-chirurgica","issn_l":"0470-8105","issn":["0470-8105","1349-8029"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313358","host_organization_name":"Japan Neurological Society","host_organization_lineage":["https://openalex.org/P4310313358"],"host_organization_lineage_names":["Japan Neurological Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurologia medico-chirurgica","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2073974950.pdf","grobid_xml":"https://content.openalex.org/works/W2073974950.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W149981375","https://openalex.org/W1527957196","https://openalex.org/W1965509007","https://openalex.org/W1974301402","https://openalex.org/W1979863485","https://openalex.org/W2002835343","https://openalex.org/W2011229517","https://openalex.org/W2013779386","https://openalex.org/W2014038245","https://openalex.org/W2023863859","https://openalex.org/W2028030167","https://openalex.org/W2040838550","https://openalex.org/W2048310782","https://openalex.org/W2049473654","https://openalex.org/W2055398896","https://openalex.org/W2060456913","https://openalex.org/W2074534105","https://openalex.org/W2122802007","https://openalex.org/W2124275134","https://openalex.org/W2128560725","https://openalex.org/W2147595657","https://openalex.org/W2150451218","https://openalex.org/W2171247860","https://openalex.org/W2272799169","https://openalex.org/W2342801915","https://openalex.org/W2356936387","https://openalex.org/W2576063645"],"related_works":["https://openalex.org/W2150451218","https://openalex.org/W1965509007","https://openalex.org/W7096266924","https://openalex.org/W2384285581","https://openalex.org/W7095553768","https://openalex.org/W2055398896","https://openalex.org/W4417533751","https://openalex.org/W2043437296","https://openalex.org/W4387618699","https://openalex.org/W1979983008"],"abstract_inverted_index":{"Eudragit-E":[0,60,90,173,207],"was":[1,116,156,171,200],"originally":[2],"developed":[3],"as":[4],"a":[5,16,104],"non-adhesive":[6],"liquid":[7],"embolic":[8],"material":[9,34,73],"in":[10,29],"the":[11,122],"late":[12],"1990s":[13],"and":[14,20,23,31,57,100,121,135,204],"is":[15,27,50],"copolymer":[17],"of":[18,41,59,107,150,177,182,194,206],"methyl":[19],"butyl":[21],"methacrylate":[22,25],"dimethylaminoethyl":[24],"that":[26],"dissolved":[28],"ethanol":[30],"iopamidol.":[32],"This":[33],"has":[35,61],"been":[36,63],"used":[37],"for":[38,46,74],"endovascular":[39,87,163],"embolization":[40,154,164,199,208],"brain":[42,78],"arteriovenous":[43],"malformations":[44],"(AVMs)":[45],"some":[47],"time":[48],"but":[49],"currently":[51],"not":[52,62],"widely":[53],"used.":[54],"Because":[55],"safety":[56,203],"feasibility":[58],"well":[64],"documented,":[65],"we":[66],"here":[67],"report":[68],"our":[69],"experience":[70],"using":[71,89],"this":[72],"treating":[75],"22":[76,95],"human":[77],"AVMs.":[79],"From":[80],"June":[81],"1998":[82],"to":[83,93,186,198],"February":[84],"2014,":[85],"30":[86],"procedures":[88],"were":[91,125,141,209],"performed":[92],"treat":[94],"patients,":[96],"including":[97],"14":[98],"men":[99],"8":[101],"women":[102],"with":[103,143,153],"mean":[105,113],"age":[106],"41.1":[108],"years":[109],"(15-70":[110],"years).":[111],"The":[112,148,158,192,202],"follow-up":[114],"period":[115],"56":[117],"months":[118],"(12-129":[119],"months),":[120],"Spetzler-Martin":[123],"grades":[124],"I":[126],"(4":[127,137],"patients),":[128,131,134],"II":[129],"(9":[130],"III":[132],"(5":[133],"IV":[136],"patients).":[138],"Residual":[139],"AVMs":[140],"treated":[142],"stereotactic":[144,167],"radiosurgery":[145,168],"or":[146,169],"surgery.":[147],"rate":[149,161,193],"complete":[151],"obliteration":[152,160],"alone":[155],"27.3%.":[157],"overall":[159],"after":[162],"with/without":[165],"subsequent":[166],"surgery":[170],"72.7%.":[172],"caused":[174],"two":[175],"cases":[176],"cerebral":[178],"infarction.":[179],"One":[180],"case":[181],"intracerebral":[183],"hemorrhage":[184],"due":[185],"postoperative":[187],"hemodynamic":[188],"changes":[189],"also":[190],"occurred.":[191],"complications":[195],"directly":[196],"related":[197],"10.0%.":[201],"effectiveness":[205],"satisfactory.":[210]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}