{"id":"https://openalex.org/W2073802424","doi":"https://doi.org/10.1093/nar/18.16.4962-a","title":"Two RFLPs detected by a cosmid at locus D16S144","display_name":"Two RFLPs detected by a cosmid at locus D16S144","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W2073802424","doi":"https://doi.org/10.1093/nar/18.16.4962-a","mag":"2073802424","pmid":"https://pubmed.ncbi.nlm.nih.gov/1975678","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/332031"},"language":"en","primary_location":{"id":"doi:10.1093/nar/18.16.4962-a","doi":"https://doi.org/10.1093/nar/18.16.4962-a","is_oa":false,"landing_page_url":"https://doi.org/10.1093/nar/18.16.4962-a","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC332031","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084939460","display_name":"Terry J. Lerner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143017","display_name":"Sequenom (United States)","ror":"https://ror.org/03rb80v65","country_code":"US","type":"company","lineage":["https://openalex.org/I4210143017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terry J. Lerner","raw_affiliation_strings":["Integrated Genetics, Inc., Framingham, MA 01701","Integrated Genetics, Inc.1 Mountain Road, Framingham, MA 01701, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrated Genetics, Inc., Framingham, MA 01701","institution_ids":["https://openalex.org/I4210143017"]},{"raw_affiliation_string":"Integrated Genetics, Inc.1 Mountain Road, Framingham, MA 01701, USA","institution_ids":["https://openalex.org/I4210143017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082960047","display_name":"Eric A. Arn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143017","display_name":"Sequenom (United States)","ror":"https://ror.org/03rb80v65","country_code":"US","type":"company","lineage":["https://openalex.org/I4210143017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Arn","raw_affiliation_strings":["Integrated Genetics, Inc. 1 Mountain Road, Framingham, MA 01701, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrated Genetics, Inc. 1 Mountain Road, Framingham, MA 01701, USA","institution_ids":["https://openalex.org/I4210143017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090348753","display_name":"Mary Ann Anderson","orcid":"https://orcid.org/0000-0002-3515-0215","observed_orcids":["https://orcid.org/0000-0002-3515-0215"]},"institutions":[{"id":"https://openalex.org/I4210143017","display_name":"Sequenom (United States)","ror":"https://ror.org/03rb80v65","country_code":"US","type":"company","lineage":["https://openalex.org/I4210143017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Ann Anderson","raw_affiliation_strings":["Integrated Genetics, Inc. 1 Mountain Road, Framingham, MA 01701, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrated Genetics, Inc. 1 Mountain Road, Framingham, MA 01701, USA","institution_ids":["https://openalex.org/I4210143017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027635355","display_name":"Katherine W. KIinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143017","display_name":"Sequenom (United States)","ror":"https://ror.org/03rb80v65","country_code":"US","type":"company","lineage":["https://openalex.org/I4210143017"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine W. KIinger","raw_affiliation_strings":["Integrated Genetics, Inc. 1 Mountain Road, Framingham, MA 01701, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrated Genetics, Inc. 1 Mountain Road, Framingham, MA 01701, USA","institution_ids":["https://openalex.org/I4210143017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061371974","display_name":"David Frederick Callen","orcid":"https://orcid.org/0000-0002-6189-9991","observed_orcids":["https://orcid.org/0000-0002-6189-9991"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David F. Callen","raw_affiliation_strings":["Adelaide Children's Hospital North Adelaide, SA 5006, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adelaide Children's Hospital North Adelaide, SA 5006, Australia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050004777","display_name":"Rudolph E. Tanzi","orcid":"https://orcid.org/0000-0002-7032-1454","observed_orcids":["https://orcid.org/0000-0002-7032-1454"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rudolph E. Tanzi","raw_affiliation_strings":["Neurogenetics Laboratory, Massachusetts General Hospital and Harvard Medical School Boston, MA 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurogenetics Laboratory, Massachusetts General Hospital and Harvard Medical School Boston, MA 02114, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3992,"currency":"USD","value_usd":3992},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.22982849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"16","first_page":"4962","last_page":"4962"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.04569999873638153,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.041999999433755875,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rflp-polymorphism","display_name":"RFLP polymorphism","score":0.753000020980835},{"id":"https://openalex.org/keywords/cosmids","display_name":"cosmids","score":0.5460000038146973},{"id":"https://openalex.org/keywords/chromosome-16","display_name":"chromosome 16","score":0.8460000157356262},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.6079999804496765},{"id":"https://openalex.org/keywords/dna-markers","display_name":"DNA markers","score":0.3089999854564667}],"concepts":[{"id":"https://openalex.org/C35101798","wikidata":"https://www.wikidata.org/wiki/Q414491","display_name":"Cosmid","level":3,"score":0.49133458733558655},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.46507665514945984},{"id":"https://openalex.org/C74916050","wikidata":"https://www.wikidata.org/wiki/Q841090","display_name":"Classics","level":1,"score":0.45213666558265686},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.4107322692871094},{"id":"https://openalex.org/C53553401","wikidata":"https://www.wikidata.org/wiki/Q47307","display_name":"Genealogy","level":1,"score":0.40568485856056213},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39238572120666504},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.34271955490112305},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3071448802947998},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12110093235969543},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.09306225180625916}],"mesh":[{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002885","descriptor_name":"Chromosomes, Human, Pair 16","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003360","descriptor_name":"Cosmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012150","descriptor_name":"Polymorphism, Restriction Fragment Length","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1093/nar/18.16.4962-a","doi":"https://doi.org/10.1093/nar/18.16.4962-a","is_oa":false,"landing_page_url":"https://doi.org/10.1093/nar/18.16.4962-a","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:232280","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC332031","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:332031","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/332031","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmid:1975678","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1975678","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:nar:18/16/4962b","doi":null,"is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/18/16/4962b","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:232280","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC332031","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2087822709"],"related_works":["https://openalex.org/W111581773","https://openalex.org/W2075279210","https://openalex.org/W1989956147","https://openalex.org/W2130768714","https://openalex.org/W2064203152","https://openalex.org/W2041709397","https://openalex.org/W2011880370","https://openalex.org/W4246241837","https://openalex.org/W2089973097","https://openalex.org/W1964753078"],"abstract_inverted_index":{"Terry":[0],"J.":[1],"Lerner,":[2],"Eric":[3],"Arn,":[4],"Mary":[5],"Ann":[6],"Anderson,":[7],"Katherine":[8],"W.":[9],"KIinger,":[10],"David":[11],"F.":[12],"Callen,":[13],"Rudolph":[14],"E.":[15],"Tanzi;":[16],"Two":[17],"RFLPs":[18],"detected":[19],"by":[20],"a":[21],"cosmid":[22],"at":[23],"locus":[24],"D16S144,":[25],"Nuc":[26]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}