{"id":"https://openalex.org/W2073590899","doi":"https://doi.org/10.1016/s0378-4347(97)00322-8","title":"Stereospecific determination of mefloquine in biological fluids by high-performance liquid chromatography","display_name":"Stereospecific determination of mefloquine in biological fluids by high-performance liquid chromatography","publication_year":1997,"publication_date":"1997-10-01","ids":{"openalex":"https://openalex.org/W2073590899","doi":"https://doi.org/10.1016/s0378-4347(97)00322-8","mag":"2073590899","pmid":"https://pubmed.ncbi.nlm.nih.gov/9390732"},"language":"en","primary_location":{"id":"doi:10.1016/s0378-4347(97)00322-8","doi":"https://doi.org/10.1016/s0378-4347(97)00322-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0378-4347(97)00322-8","pdf_url":null,"source":{"id":"https://openalex.org/S14366386","display_name":"Journal of Chromatography B Biomedical Sciences and Applications","issn_l":"0378-4347","issn":["0378-4347","1387-2273","1872-812X","1878-5603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography B: Biomedical Sciences and Applications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003321914","display_name":"Effat Souri","orcid":"https://orcid.org/0000-0002-6145-4167","observed_orcids":["https://orcid.org/0000-0002-6145-4167"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Effat Souri","raw_affiliation_strings":["Department of Medicinal Chemistry, Faculty of Pharmacy, University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry, Faculty of Pharmacy, University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110075884","display_name":"Hassan Farsam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Hassan Farsam","raw_affiliation_strings":["Department of Medicinal Chemistry, Faculty of Pharmacy, University of Medical Sciences, Tehran 14155-6451, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry, Faculty of Pharmacy, University of Medical Sciences, Tehran 14155-6451, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083326383","display_name":"Fakhreddin Jamali","orcid":"https://orcid.org/0000-0003-0277-853X","observed_orcids":["https://orcid.org/0000-0003-0277-853X"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Fakhreddin Jamali","raw_affiliation_strings":["Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alb. T6G 2N8, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alb. T6G 2N8, Canada","institution_ids":["https://openalex.org/I154425047"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110075884"],"corresponding_institution_ids":["https://openalex.org/I70640408"],"apc_list":null,"apc_paid":null,"fwci":0.3018,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.52458509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"700","issue":"1-2","first_page":"215","last_page":"222"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mefloquine","display_name":"mefloquine","score":1.0},{"id":"https://openalex.org/keywords/enantiomers","display_name":"enantiomers","score":0.8159999847412109},{"id":"https://openalex.org/keywords/stereoselective-determination","display_name":"stereoselective determination","score":0.8560000061988831},{"id":"https://openalex.org/keywords/plasma","display_name":"plasma","score":0.5550000071525574},{"id":"https://openalex.org/keywords/urine","display_name":"urine","score":0.972000002861023},{"id":"https://openalex.org/keywords/whole-blood","display_name":"whole blood","score":0.9890000224113464},{"id":"https://openalex.org/keywords/chiral-derivatization","display_name":"chiral derivatization","score":0.875},{"id":"https://openalex.org/keywords/diastereomers","display_name":"diastereomers","score":0.7390000224113464},{"id":"https://openalex.org/keywords/liquid-liquid-extraction","display_name":"liquid-liquid extraction","score":0.8169999718666077},{"id":"https://openalex.org/keywords/antimalarial-drugs","display_name":"antimalarial drugs","score":0.7680000066757202}],"concepts":[{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.898297905921936},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8075444102287292},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.6619284152984619},{"id":"https://openalex.org/C138716334","wikidata":"https://www.wikidata.org/wiki/Q268477","display_name":"Diastereomer","level":2,"score":0.6521708965301514},{"id":"https://openalex.org/C486523","wikidata":"https://www.wikidata.org/wiki/Q494483","display_name":"Enantiomer","level":2,"score":0.626937747001648},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.6185495853424072},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.539709210395813},{"id":"https://openalex.org/C2776923573","wikidata":"https://www.wikidata.org/wiki/Q2294884","display_name":"Derivatization","level":3,"score":0.5177706480026245},{"id":"https://openalex.org/C2777077568","wikidata":"https://www.wikidata.org/wiki/Q150440","display_name":"Hexane","level":2,"score":0.49495452642440796},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10736498236656189}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000962","descriptor_name":"Antimalarials","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000962","descriptor_name":"Antimalarials","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D000962","descriptor_name":"Antimalarials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013056","descriptor_name":"Spectrophotometry, Ultraviolet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015767","descriptor_name":"Mefloquine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015767","descriptor_name":"Mefloquine","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D015767","descriptor_name":"Mefloquine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0378-4347(97)00322-8","doi":"https://doi.org/10.1016/s0378-4347(97)00322-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0378-4347(97)00322-8","pdf_url":null,"source":{"id":"https://openalex.org/S14366386","display_name":"Journal of Chromatography B Biomedical Sciences and Applications","issn_l":"0378-4347","issn":["0378-4347","1387-2273","1872-812X","1878-5603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography B: Biomedical Sciences and Applications","raw_type":"journal-article"},{"id":"pmid:9390732","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9390732","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chromatography. B, Biomedical sciences and applications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W152056264","https://openalex.org/W174622520","https://openalex.org/W1967043268","https://openalex.org/W1976525424","https://openalex.org/W1983988243","https://openalex.org/W1992482403","https://openalex.org/W1998738989","https://openalex.org/W2000726910","https://openalex.org/W2000851763","https://openalex.org/W2002712081","https://openalex.org/W2012908210","https://openalex.org/W2013021255","https://openalex.org/W2016819381","https://openalex.org/W2027560783","https://openalex.org/W2029094910","https://openalex.org/W2045750311","https://openalex.org/W2054535062","https://openalex.org/W2056535536","https://openalex.org/W2059814420","https://openalex.org/W2063689094","https://openalex.org/W2072682889","https://openalex.org/W2095512635","https://openalex.org/W2320180625","https://openalex.org/W2334093465"],"related_works":["https://openalex.org/W1931767587","https://openalex.org/W1998738989","https://openalex.org/W2000726910","https://openalex.org/W2063689094","https://openalex.org/W2054535062","https://openalex.org/W2036477132","https://openalex.org/W1859596670","https://openalex.org/W1967043268","https://openalex.org/W2045267351","https://openalex.org/W2967278330"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}