{"id":"https://openalex.org/W2073557461","doi":"https://doi.org/10.1016/0014-2999(93)90027-f","title":"In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist","display_name":"In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist","publication_year":1993,"publication_date":"1993-12-01","ids":{"openalex":"https://openalex.org/W2073557461","doi":"https://doi.org/10.1016/0014-2999(93)90027-f","mag":"2073557461","pmid":"https://pubmed.ncbi.nlm.nih.gov/7509286"},"language":"en","primary_location":{"id":"doi:10.1016/0014-2999(93)90027-f","doi":"https://doi.org/10.1016/0014-2999(93)90027-f","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-2999(93)90027-f","pdf_url":null,"source":{"id":"https://openalex.org/S187816532","display_name":"European Journal of Pharmacology","issn_l":"0014-2999","issn":["0014-2999","1879-0712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113589235","display_name":"Xavier Emonds\u2010Alt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Xavier Emonds-Alt","raw_affiliation_strings":["Sanofi Recherche, Montpellier, France","Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, Montpellier, France","institution_ids":["https://openalex.org/I3018075036"]},{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029960785","display_name":"Jean-Daniel Doutremepuich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Daniel Doutremepuich","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041194140","display_name":"Michel H\u00e9aulme","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Michel Heaulme","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073079789","display_name":"Gervais Neliat","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gervais Neliat","raw_affiliation_strings":["Cerep, Le Bois L'Ev\u00eaque, F-86600 Celle L'Evescault, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerep, Le Bois L'Ev\u00eaque, F-86600 Celle L'Evescault, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088037920","display_name":"Vincent Santucci","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vincent Santucci","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111597252","display_name":"R\u00e9gis Steinberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Regis Steinberg","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008369945","display_name":"Pol Vilain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pol Vilain","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061738068","display_name":"Daniel Bichon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Daniel Bichon","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014412277","display_name":"Jean-Philippe Ducoux","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Philippe Ducoux","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003380039","display_name":"Vincenzo Proietto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vincenzo Proietto","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035215054","display_name":"Didier Van Broeck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Didier Van Broeck","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110129721","display_name":"Philippe Soubri\u00e9","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Philippe Soubri\u00e9","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111932689","display_name":"G\u00e9rard Le Fur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"G\u00e9rard Le Fur","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111621439","display_name":"Jean-Claude Breli\u00e8re","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018075036","display_name":"Sanofi (France)","ror":"https://ror.org/02n6c9837","country_code":"FR","type":"company","lineage":["https://openalex.org/I3018075036"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Claude Breli\u00e9re","raw_affiliation_strings":["Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sanofi Recherche, 371 rue du Professeur J. Blayac, F-34184 Montpellier Cedex 04, France","institution_ids":["https://openalex.org/I3018075036"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113589235"],"corresponding_institution_ids":["https://openalex.org/I3018075036"],"apc_list":{"value":3230,"currency":"USD","value_usd":3230},"apc_paid":null,"fwci":8.3729,"has_fulltext":false,"cited_by_count":371,"citation_normalized_percentile":{"value":0.98653738,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"250","issue":"3","first_page":"403","last_page":"413"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sr140333","display_name":"SR140333","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tachykinin-nk1-receptor-antagonists","display_name":"tachykinin NK1 receptor antagonist","score":0.9089999794960022},{"id":"https://openalex.org/keywords/substance-p","display_name":"substance P","score":0.8930000066757202},{"id":"https://openalex.org/keywords/nonpeptide-antagonists","display_name":"non-peptide antagonists","score":0.7179999947547913},{"id":"https://openalex.org/keywords/noncompetitive-antagonism","display_name":"non-competitive antagonism","score":0.7509999871253967},{"id":"https://openalex.org/keywords/acetylcholine-release","display_name":"acetylcholine release","score":0.746999979019165},{"id":"https://openalex.org/keywords/striatum","display_name":"striatum","score":0.6949999928474426},{"id":"https://openalex.org/keywords/hypotension","display_name":"hypotension","score":0.8029999732971191},{"id":"https://openalex.org/keywords/bronchoconstriction","display_name":"bronchoconstriction","score":0.996999979019165},{"id":"https://openalex.org/keywords/plasma-extravasation","display_name":"plasma extravasation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/nociceptive-stimulation","display_name":"nociceptive stimulation","score":0.765999972820282},{"id":"https://openalex.org/keywords/thalamic-neurons","display_name":"thalamic neurons","score":0.9629999995231628},{"id":"https://openalex.org/keywords/pulmonary-artery-relaxation","display_name":"pulmonary artery relaxation","score":0.7580000162124634},{"id":"https://openalex.org/keywords/ileum-contraction","display_name":"ileum contraction","score":0.8050000071525574},{"id":"https://openalex.org/keywords/neurokinin-receptors","display_name":"neurokinin receptors","score":0.6819999814033508}],"concepts":[{"id":"https://openalex.org/C55938493","wikidata":"https://www.wikidata.org/wiki/Q426034","display_name":"Tachykinin receptor","level":5,"score":0.7544240951538086},{"id":"https://openalex.org/C2776533618","wikidata":"https://www.wikidata.org/wiki/Q411041","display_name":"Substance P","level":4,"score":0.7538819909095764},{"id":"https://openalex.org/C2777056410","wikidata":"https://www.wikidata.org/wiki/Q408566","display_name":"Neurokinin A","level":5,"score":0.7381385564804077},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6263139247894287},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6195000410079956},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6114252209663391},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4887104034423828},{"id":"https://openalex.org/C202871150","wikidata":"https://www.wikidata.org/wiki/Q12744608","display_name":"NK1 receptor antagonist","level":5,"score":0.4556349813938141},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.43332213163375854},{"id":"https://openalex.org/C2775910092","wikidata":"https://www.wikidata.org/wiki/Q180623","display_name":"Acetylcholine","level":2,"score":0.4269481897354126},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.2896853983402252},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1088545024394989}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002199","descriptor_name":"Capillary Permeability","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007022","descriptor_name":"Hypotension","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D007022","descriptor_name":"Hypotension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009126","descriptor_name":"Muscle Relaxation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009130","descriptor_name":"Muscle, Smooth","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010880","descriptor_name":"Piperidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011812","descriptor_name":"Quinuclidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013373","descriptor_name":"Substance P","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D013373","descriptor_name":"Substance P","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013373","descriptor_name":"Substance P","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016084","descriptor_name":"Bronchoconstriction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018040","descriptor_name":"Receptors, Neurokinin-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064729","descriptor_name":"Neurokinin-1 Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0014-2999(93)90027-f","doi":"https://doi.org/10.1016/0014-2999(93)90027-f","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-2999(93)90027-f","pdf_url":null,"source":{"id":"https://openalex.org/S187816532","display_name":"European Journal of Pharmacology","issn_l":"0014-2999","issn":["0014-2999","1879-0712"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Pharmacology","raw_type":"journal-article"},{"id":"pmid:7509286","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7509286","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of pharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W249845531","https://openalex.org/W1547131709","https://openalex.org/W1573840829","https://openalex.org/W1892962265","https://openalex.org/W1911199944","https://openalex.org/W1965016519","https://openalex.org/W1972802593","https://openalex.org/W1977063430","https://openalex.org/W1981318858","https://openalex.org/W1982770942","https://openalex.org/W1995901467","https://openalex.org/W1997913414","https://openalex.org/W2001246212","https://openalex.org/W2004799627","https://openalex.org/W2009936187","https://openalex.org/W2010196759","https://openalex.org/W2022072984","https://openalex.org/W2028502625","https://openalex.org/W2031706219","https://openalex.org/W2041936147","https://openalex.org/W2053583807","https://openalex.org/W2055292745","https://openalex.org/W2057971042","https://openalex.org/W2059900452","https://openalex.org/W2071505167","https://openalex.org/W2073233024","https://openalex.org/W2077714000","https://openalex.org/W2086892522","https://openalex.org/W2086913393","https://openalex.org/W2089376420","https://openalex.org/W2089414938","https://openalex.org/W2091303128","https://openalex.org/W2113579215","https://openalex.org/W2121785350","https://openalex.org/W2146390263","https://openalex.org/W2161498398","https://openalex.org/W2163815564","https://openalex.org/W2172113265","https://openalex.org/W2269968001","https://openalex.org/W2326197515","https://openalex.org/W3021378521","https://openalex.org/W3099977804","https://openalex.org/W6639860611","https://openalex.org/W6668213207","https://openalex.org/W6672082403","https://openalex.org/W6700787358"],"related_works":["https://openalex.org/W2139131684","https://openalex.org/W2030332142","https://openalex.org/W2031034264","https://openalex.org/W2021433535","https://openalex.org/W2027529370","https://openalex.org/W2018339076","https://openalex.org/W2052360390","https://openalex.org/W4230004586","https://openalex.org/W2089218012","https://openalex.org/W2067141584"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}