{"id":"https://openalex.org/W2073553740","doi":"https://doi.org/10.1111/j.1444-0938.2005.tb06711.x","title":"Anatomy and development of the macula: specialisation and the vulnerability to macular degeneration","display_name":"Anatomy and development of the macula: specialisation and the vulnerability to macular degeneration","publication_year":2005,"publication_date":"2005-09-01","ids":{"openalex":"https://openalex.org/W2073553740","doi":"https://doi.org/10.1111/j.1444-0938.2005.tb06711.x","mag":"2073553740","pmid":"https://pubmed.ncbi.nlm.nih.gov/16255686"},"language":"en","primary_location":{"id":"doi:10.1111/j.1444-0938.2005.tb06711.x","doi":"https://doi.org/10.1111/j.1444-0938.2005.tb06711.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1444-0938.2005.tb06711.x","pdf_url":null,"source":{"id":"https://openalex.org/S110643388","display_name":"Clinical and Experimental Optometry","issn_l":"0816-4622","issn":["0816-4622","0817-881X","1444-0938"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Optometry","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090224250","display_name":"Jan M. Provis","orcid":"https://orcid.org/0000-0002-6405-2868","observed_orcids":["https://orcid.org/0000-0002-6405-2868"]},"institutions":[{"id":"https://openalex.org/I118347636","display_name":"Australian National University","ror":"https://ror.org/019wvm592","country_code":"AU","type":"education","lineage":["https://openalex.org/I118347636"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jan M. Provis","raw_affiliation_strings":["Research School of Biological Sciences, The Australian National University, Canberra, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research School of Biological Sciences, The Australian National University, Canberra, Australia","institution_ids":["https://openalex.org/I118347636"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113396482","display_name":"Philip L. Penfold","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118347636","display_name":"Australian National University","ror":"https://ror.org/019wvm592","country_code":"AU","type":"education","lineage":["https://openalex.org/I118347636"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Philip L. Penfold","raw_affiliation_strings":["Regenera Ltd, Canberra Airport, ACT, \tAustralia","Research School of Biological Sciences, The Australian National University, Canberra, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Regenera Ltd, Canberra Airport, ACT, \tAustralia","institution_ids":[]},{"raw_affiliation_string":"Research School of Biological Sciences, The Australian National University, Canberra, Australia","institution_ids":["https://openalex.org/I118347636"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057988533","display_name":"Elisa Eleanor Cornish","orcid":"https://orcid.org/0000-0003-3898-8811","observed_orcids":["https://orcid.org/0000-0003-3898-8811"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Elisa E. Cornish","raw_affiliation_strings":["Save Sight Institute, University of Sydney, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Save Sight Institute, University of Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047119037","display_name":"Trent M. Sandercoe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Trent M. Sandercoe","raw_affiliation_strings":["Save Sight Institute, University of Sydney, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Save Sight Institute, University of Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070288036","display_name":"Michele C. Madigan","orcid":"https://orcid.org/0000-0003-1053-6979","observed_orcids":["https://orcid.org/0000-0003-1053-6979"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Michele C. Madigan","raw_affiliation_strings":["Save Sight Institute, University of Sydney, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Save Sight Institute, University of Sydney, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2900,"currency":"USD","value_usd":2900},"apc_paid":null,"fwci":1.4265,"has_fulltext":false,"cited_by_count":206,"citation_normalized_percentile":{"value":0.79345088,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"88","issue":"5","first_page":"269","last_page":"281"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9541000127792358,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.041600000113248825,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macula","display_name":"macula","score":0.9559999704360962},{"id":"https://openalex.org/keywords/macular-degeneration","display_name":"macular degeneration","score":0.8389999866485596},{"id":"https://openalex.org/keywords/retinal-development","display_name":"retinal development","score":0.75},{"id":"https://openalex.org/keywords/cone-photoreceptors","display_name":"cone photoreceptors","score":0.8500000238418579},{"id":"https://openalex.org/keywords/fovea","display_name":"fovea","score":0.6119999885559082},{"id":"https://openalex.org/keywords/choriocapillaris","display_name":"choriocapillaris","score":0.9390000104904175},{"id":"https://openalex.org/keywords/retinal-blood-supply","display_name":"retinal blood supply","score":0.9449999928474426},{"id":"https://openalex.org/keywords/muller-cells","display_name":"M\u00fcller cells","score":0.5839999914169312},{"id":"https://openalex.org/keywords/retinal-ganglion-cells","display_name":"retinal ganglion cells","score":0.8840000033378601},{"id":"https://openalex.org/keywords/bruch-s-membrane","display_name":"Bruch's membrane","score":0.7789999842643738},{"id":"https://openalex.org/keywords/retinal-pigment-epithelium","display_name":"retinal pigment epithelium","score":0.996999979019165},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7379999756813049},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/age-related-macular-degeneration","display_name":"age-related macular degeneration","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.8517294526100159},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6256141066551208},{"id":"https://openalex.org/C30181142","wikidata":"https://www.wikidata.org/wiki/Q865103","display_name":"Foveal","level":3,"score":0.6198246479034424},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5114411115646362},{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.47065678238868713},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4545218050479889},{"id":"https://openalex.org/C2778024200","wikidata":"https://www.wikidata.org/wiki/Q2346242","display_name":"Retinal pigment epithelium","level":3,"score":0.45046091079711914},{"id":"https://openalex.org/C2776694393","wikidata":"https://www.wikidata.org/wiki/Q271762","display_name":"Choroid","level":3,"score":0.43309828639030457},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.40613123774528503},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3930816948413849},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30732351541519165}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008266","descriptor_name":"Macula Lutea","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D008266","descriptor_name":"Macula Lutea","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1444-0938.2005.tb06711.x","doi":"https://doi.org/10.1111/j.1444-0938.2005.tb06711.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1444-0938.2005.tb06711.x","pdf_url":null,"source":{"id":"https://openalex.org/S110643388","display_name":"Clinical and Experimental Optometry","issn_l":"0816-4622","issn":["0816-4622","0817-881X","1444-0938"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Optometry","raw_type":"journal-article"},{"id":"pmid:16255686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16255686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & experimental optometry","raw_type":"Journal Article"},{"id":"pmh:oai:openresearch-repository.anu.edu.au:1885/83135","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1885/83135","pdf_url":null,"source":{"id":"https://openalex.org/S4306402539","display_name":"ANU Open Research (Australian National University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118347636","host_organization_name":"Australian National University","host_organization_lineage":["https://openalex.org/I118347636"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical and Experimental Optometry","raw_type":"Journal article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":122,"referenced_works":["https://openalex.org/W12805694","https://openalex.org/W30467198","https://openalex.org/W91872680","https://openalex.org/W127777169","https://openalex.org/W130062870","https://openalex.org/W196576021","https://openalex.org/W207750732","https://openalex.org/W1483963847","https://openalex.org/W1484256565","https://openalex.org/W1488792046","https://openalex.org/W1496373917","https://openalex.org/W1499757659","https://openalex.org/W1509391708","https://openalex.org/W1539610146","https://openalex.org/W1543034495","https://openalex.org/W1565600091","https://openalex.org/W1572398729","https://openalex.org/W1582738275","https://openalex.org/W1590548658","https://openalex.org/W1596751131","https://openalex.org/W1607763659","https://openalex.org/W1618162090","https://openalex.org/W1731074416","https://openalex.org/W1780202576","https://openalex.org/W1817006636","https://openalex.org/W1883306593","https://openalex.org/W1901360874","https://openalex.org/W1964602001","https://openalex.org/W1965404473","https://openalex.org/W1966067258","https://openalex.org/W1966318341","https://openalex.org/W1966785179","https://openalex.org/W1968298081","https://openalex.org/W1976540988","https://openalex.org/W1980685924","https://openalex.org/W1980969801","https://openalex.org/W1983613539","https://openalex.org/W1984358837","https://openalex.org/W1985235161","https://openalex.org/W1987648803","https://openalex.org/W1987756195","https://openalex.org/W1989820156","https://openalex.org/W1991870061","https://openalex.org/W1992112653","https://openalex.org/W1992859141","https://openalex.org/W1994014733","https://openalex.org/W1997956353","https://openalex.org/W2000399151","https://openalex.org/W2003965310","https://openalex.org/W2006480537","https://openalex.org/W2007695162","https://openalex.org/W2010099441","https://openalex.org/W2011403734","https://openalex.org/W2014393992","https://openalex.org/W2015562927","https://openalex.org/W2016145428","https://openalex.org/W2021338387","https://openalex.org/W2024947141","https://openalex.org/W2025372063","https://openalex.org/W2025398169","https://openalex.org/W2025958760","https://openalex.org/W2026691719","https://openalex.org/W2030860017","https://openalex.org/W2034347345","https://openalex.org/W2039792596","https://openalex.org/W2040965438","https://openalex.org/W2044257198","https://openalex.org/W2045247659","https://openalex.org/W2046638324","https://openalex.org/W2048270119","https://openalex.org/W2051060275","https://openalex.org/W2053229392","https://openalex.org/W2055153760","https://openalex.org/W2056898486","https://openalex.org/W2056989349","https://openalex.org/W2057559671","https://openalex.org/W2063709616","https://openalex.org/W2069997798","https://openalex.org/W2070394325","https://openalex.org/W2070625860","https://openalex.org/W2072520225","https://openalex.org/W2073119489","https://openalex.org/W2073330897","https://openalex.org/W2077774442","https://openalex.org/W2079957682","https://openalex.org/W2086178001","https://openalex.org/W2088082580","https://openalex.org/W2088551743","https://openalex.org/W2093498435","https://openalex.org/W2095075033","https://openalex.org/W2096824046","https://openalex.org/W2096926081","https://openalex.org/W2096985787","https://openalex.org/W2098193587","https://openalex.org/W2098714675","https://openalex.org/W2109304711","https://openalex.org/W2110391446","https://openalex.org/W2111572168","https://openalex.org/W2111684548","https://openalex.org/W2113784410","https://openalex.org/W2117386992","https://openalex.org/W2122345966","https://openalex.org/W2123460349","https://openalex.org/W2124223884","https://openalex.org/W2129003569","https://openalex.org/W2142863049","https://openalex.org/W2152381240","https://openalex.org/W2156993091","https://openalex.org/W2160073622","https://openalex.org/W2161038338","https://openalex.org/W2161235995","https://openalex.org/W2170201303","https://openalex.org/W2185693177","https://openalex.org/W2217246609","https://openalex.org/W2230100068","https://openalex.org/W2273142706","https://openalex.org/W2400001653","https://openalex.org/W2410139671","https://openalex.org/W3145351529","https://openalex.org/W4210631414","https://openalex.org/W4232505429","https://openalex.org/W4253427643"],"related_works":["https://openalex.org/W7132114278","https://openalex.org/W3175934911","https://openalex.org/W1572398729","https://openalex.org/W7160551106","https://openalex.org/W2040965438","https://openalex.org/W2164574799","https://openalex.org/W2088357082","https://openalex.org/W1615651587","https://openalex.org/W2089749058","https://openalex.org/W3008851651"],"abstract_inverted_index":{"The":[0,11,23,35,46],"central":[1],"retina":[2,17,70,146,220],"in":[3,18,52,94,97,138,175,195,225,248],"primates":[4],"is":[5,79,87,104],"adapted":[6],"for":[7],"high":[8,25],"acuity":[9],"vision.":[10],"most":[12],"significant":[13],"adaptations":[14,180],"to":[15,65,127,186,214,232],"neural":[16,77,145,219],"this":[19,113,249],"respect":[20],"are:":[21],"1.":[22],"very":[24],"density":[26,75],"of":[27,37,48,68,76,82,108,140,143,156,169,192,210,222,242],"cone":[28],"photoreceptors":[29],"on":[30,58,208],"the":[31,53,59,66,69,73,109,119,133,144,157,160,166,176,182,190,200,215,226,229,236,240],"visual":[32,60],"axis;":[33],"2.":[34],"dominance":[36],"Midget":[38],"pathways":[39],"arising":[40],"from":[41,132],"these":[42,179],"cones":[43],"and":[44,55,85,92,100,171,198,212,217,228,239],"3.":[45],"diminishment":[47],"retinal":[49,122,201],"blood":[50,63,130],"supply":[51,64,131,168],"macula,":[54],"its":[56],"absence":[57],"axis.":[61],"Restricted":[62],"part":[67],"that":[71,117,153],"has":[72],"highest":[74],"elements":[78],"paradoxical.":[80],"Inhibition":[81],"vascular":[83],"growth":[84],"proliferation":[86],"evident":[88],"during":[89,106,125],"foetal":[90],"life":[91],"results":[93],"metabolic":[95,141],"stress":[96,244],"ganglion":[98],"cells":[99],"Muller":[101],"cells,":[102],"which":[103,135],"resolved":[105],"formation":[107],"foveal":[110,161],"depression.":[111],"In":[112],"review":[114],"we":[115],"argue":[116,151],"at":[118],"macula":[120],"stressed":[121],"neurons":[123],"adapt":[124],"development":[126],"a":[128],"limited":[129],"choriocapillaris,":[134],"supplies":[136],"little":[137],"excess":[139],"demand":[142],"under":[147],"normal":[148],"conditions.":[149],"We":[150],"also":[152],"while":[154],"adaptation":[155],"choriocapillaris":[158,227],"underlying":[159],"region":[162,183],"may":[163],"initially":[164],"augment":[165],"local":[167],"oxygen":[170,211],"nutrients":[172,213],"by":[173],"diffusion,":[174],"long":[177],"term":[178],"make":[181],"more":[184],"vulnerable":[185],"age-related":[187],"changes,":[188],"including":[189],"accumulation":[191],"insoluble":[193],"material":[194],"Bruch's":[196],"membrane":[197],"beneath":[199],"pigment":[202],"epithelium.":[203],"These":[204],"changes":[205],"eventually":[206],"impact":[207],"delivery":[209],"RPE":[216],"outer":[218],"because":[221],"reduced":[223],"flow":[224],"increasing":[230],"barriers":[231],"effective":[233],"diffusion.":[234],"Both":[235],"inflammatory":[237],"response":[238],"sequelae":[241],"oxidative":[243],"are":[245],"predictable":[246],"outcomes":[247],"scenario.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}