{"id":"https://openalex.org/W2073485575","doi":"https://doi.org/10.1016/j.neulet.2004.04.035","title":"Dihydrotestosterone may inhibit hypothalamo\u2013pituitary\u2013adrenal activity by acting through estrogen receptor in the male mouse","display_name":"Dihydrotestosterone may inhibit hypothalamo\u2013pituitary\u2013adrenal activity by acting through estrogen receptor in the male mouse","publication_year":2004,"publication_date":"2004-06-25","ids":{"openalex":"https://openalex.org/W2073485575","doi":"https://doi.org/10.1016/j.neulet.2004.04.035","mag":"2073485575","pmid":"https://pubmed.ncbi.nlm.nih.gov/15234470"},"language":"en","primary_location":{"id":"doi:10.1016/j.neulet.2004.04.035","doi":"https://doi.org/10.1016/j.neulet.2004.04.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neulet.2004.04.035","pdf_url":null,"source":{"id":"https://openalex.org/S203050076","display_name":"Neuroscience Letters","issn_l":"0304-3940","issn":["0304-3940","1872-7972"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Letters","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062034653","display_name":"Trent D Lund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Trent D Lund","raw_affiliation_strings":["Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA. tlund@colostate.edu","Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA. tlund@colostate.edu","institution_ids":["https://openalex.org/I92446798"]},{"raw_affiliation_string":"Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109233501","display_name":"Daniel J. Munson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel J Munson","raw_affiliation_strings":["Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063450975","display_name":"Megan E. Haldy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan E Haldy","raw_affiliation_strings":["Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA","institution_ids":["https://openalex.org/I92446798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042132328","display_name":"Robert J. Handa","orcid":"https://orcid.org/0000-0001-9131-2808","observed_orcids":["https://orcid.org/0000-0001-9131-2808"]},"institutions":[{"id":"https://openalex.org/I92446798","display_name":"Colorado State University","ror":"https://ror.org/03k1gpj17","country_code":"US","type":"education","lineage":["https://openalex.org/I92446798"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert J Handa","raw_affiliation_strings":["Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, Colorado State University, Anatomy W103, 1617 Campus Delivery, Fort Collins, CO 80523-1670, USA","institution_ids":["https://openalex.org/I92446798"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062034653"],"corresponding_institution_ids":["https://openalex.org/I92446798"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":null,"fwci":1.5064,"has_fulltext":false,"cited_by_count":80,"citation_normalized_percentile":{"value":0.78614719,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"365","issue":"1","first_page":"43","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.8154000043869019,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.1388999968767166,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.030799999833106995,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dihydrotestosterone","display_name":"dihydrotestosterone","score":1.0},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.8949999809265137},{"id":"https://openalex.org/keywords/corticosterone","display_name":"corticosterone","score":0.9139999747276306},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.8769999742507935},{"id":"https://openalex.org/keywords/estrogen-receptor","display_name":"estrogen receptor","score":0.7609999775886536},{"id":"https://openalex.org/keywords/estradiol-benzoate","display_name":"estradiol benzoate","score":0.9419999718666077},{"id":"https://openalex.org/keywords/androgen-metabolism","display_name":"androgen metabolism","score":0.7289999723434448},{"id":"https://openalex.org/keywords/flutamide","display_name":"flutamide","score":0.7889999747276306},{"id":"https://openalex.org/keywords/tamoxifen","display_name":"tamoxifen","score":0.9980000257492065},{"id":"https://openalex.org/keywords/androgen-receptor","display_name":"androgen receptor","score":0.7250000238418579},{"id":"https://openalex.org/keywords/male-mice","display_name":"male mice","score":0.5009999871253967}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.868179202079773},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8666456341743469},{"id":"https://openalex.org/C2779881493","wikidata":"https://www.wikidata.org/wiki/Q411054","display_name":"Dihydrotestosterone","level":4,"score":0.8152592182159424},{"id":"https://openalex.org/C2778313021","wikidata":"https://www.wikidata.org/wiki/Q418669","display_name":"Flutamide","level":5,"score":0.6517571210861206},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.6281087398529053},{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.6139822602272034},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.5522791147232056},{"id":"https://openalex.org/C2778506572","wikidata":"https://www.wikidata.org/wiki/Q11450699","display_name":"Estradiol benzoate","level":4,"score":0.510903537273407},{"id":"https://openalex.org/C61367390","wikidata":"https://www.wikidata.org/wiki/Q416601","display_name":"Androgen receptor","level":4,"score":0.47330203652381897},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.4650859236717224},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.42523109912872314},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40456971526145935},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3840089440345764},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3789612948894501},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.37046289443969727},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1743292510509491},{"id":"https://openalex.org/C8264082","wikidata":"https://www.wikidata.org/wiki/Q7113259","display_name":"Ovariectomized rat","level":3,"score":0.08341583609580994},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.0},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000726","descriptor_name":"Androgen Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003345","descriptor_name":"Corticosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004965","descriptor_name":"Estrogen Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005485","descriptor_name":"Flutamide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009919","descriptor_name":"Orchiectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011960","descriptor_name":"Receptors, Estrogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012149","descriptor_name":"Restraint, Physical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013196","descriptor_name":"Dihydrotestosterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013196","descriptor_name":"Dihydrotestosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013629","descriptor_name":"Tamoxifen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neulet.2004.04.035","doi":"https://doi.org/10.1016/j.neulet.2004.04.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neulet.2004.04.035","pdf_url":null,"source":{"id":"https://openalex.org/S203050076","display_name":"Neuroscience Letters","issn_l":"0304-3940","issn":["0304-3940","1872-7972"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience Letters","raw_type":"journal-article"},{"id":"pmid:15234470","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15234470","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6878326100","display_name":"Gonadal Steroid Receptors and the Hypothalamo-Pituitary-Adrenal Axis","funder_award_id":"R01NS039951","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8408437498","display_name":null,"funder_award_id":"NS39951","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320320987","display_name":"Curtin University of Technology","ror":"https://ror.org/02n415q13"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1554082852","https://openalex.org/W1855071757","https://openalex.org/W1964261549","https://openalex.org/W1975058795","https://openalex.org/W1977333419","https://openalex.org/W1980421324","https://openalex.org/W1996471481","https://openalex.org/W2003656057","https://openalex.org/W2007269095","https://openalex.org/W2012915393","https://openalex.org/W2025814399","https://openalex.org/W2029193046","https://openalex.org/W2030063067","https://openalex.org/W2045534445","https://openalex.org/W2057480520","https://openalex.org/W2073417859","https://openalex.org/W2073883348","https://openalex.org/W2084086076","https://openalex.org/W2092107317","https://openalex.org/W2151386071","https://openalex.org/W2170425512","https://openalex.org/W4299313234"],"related_works":["https://openalex.org/W2080190440","https://openalex.org/W1988626382","https://openalex.org/W1993026202","https://openalex.org/W2046029139","https://openalex.org/W2042179361","https://openalex.org/W2030063067","https://openalex.org/W2069403955","https://openalex.org/W2063908059","https://openalex.org/W4412494383","https://openalex.org/W2004907725"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}