{"id":"https://openalex.org/W2073039121","doi":"https://doi.org/10.1042/bj20041686","title":"Molecular basis of N-acetylglucosaminyltransferase I deficiency in Arabidopsis thaliana plants lacking complex N-glycans","display_name":"Molecular basis of N-acetylglucosaminyltransferase I deficiency in Arabidopsis thaliana plants lacking complex N-glycans","publication_year":2005,"publication_date":"2005-04-05","ids":{"openalex":"https://openalex.org/W2073039121","doi":"https://doi.org/10.1042/bj20041686","mag":"2073039121","pmid":"https://pubmed.ncbi.nlm.nih.gov/15537386","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1134966"},"language":"en","primary_location":{"id":"doi:10.1042/bj20041686","doi":"https://doi.org/10.1042/bj20041686","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj20041686","pdf_url":"https://portlandpress.com/biochemj/article-pdf/387/2/385/720226/bj3870385.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://portlandpress.com/biochemj/article-pdf/387/2/385/720226/bj3870385.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010190025","display_name":"Richard Strasser","orcid":"https://orcid.org/0000-0001-8764-6530","observed_orcids":["https://orcid.org/0000-0001-8764-6530"]},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Richard STRASSER","raw_affiliation_strings":["Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069156139","display_name":"Johannes Stadlmann","orcid":"https://orcid.org/0000-0001-5693-6690","observed_orcids":["https://orcid.org/0000-0001-5693-6690"]},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Johannes STADLMANN","raw_affiliation_strings":["Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036335718","display_name":"Barbara Svoboda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Barbara SVOBODA","raw_affiliation_strings":["Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040086885","display_name":"Friedrich Altmann","orcid":"https://orcid.org/0000-0002-0112-7877","observed_orcids":["https://orcid.org/0000-0002-0112-7877"]},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Friedrich ALTMANN","raw_affiliation_strings":["Department f\u00fcr Chemie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department f\u00fcr Chemie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038939942","display_name":"Josef Gl\u00f6ssl","orcid":"https://orcid.org/0000-0002-5042-8828","observed_orcids":["https://orcid.org/0000-0002-5042-8828"]},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Josef GL\u00d6SSL","raw_affiliation_strings":["Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065762571","display_name":"Lukas Mach","orcid":"https://orcid.org/0000-0001-9013-5408","observed_orcids":["https://orcid.org/0000-0001-9013-5408"]},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Lukas MACH","raw_affiliation_strings":["Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department f\u00fcr Angewandte Pflanzenwissenschaften und Pflanzenbiotechnologie, Institut f\u00fcr Angewandte Genetik und Zellbiologie, Universit\u00e4t f\u00fcr Bodenkultur Wien, Muthgasse 18, A-1190 Wien, Austria","institution_ids":["https://openalex.org/I92869138"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010190025","https://openalex.org/A5036335718","https://openalex.org/A5065762571","https://openalex.org/A5069156139"],"corresponding_institution_ids":["https://openalex.org/I92869138"],"apc_list":null,"apc_paid":null,"fwci":1.9616,"has_fulltext":true,"cited_by_count":106,"citation_normalized_percentile":{"value":0.85363248,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"387","issue":"2","first_page":"385","last_page":"391"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10869","display_name":"Polysaccharides and Plant Cell Walls","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/n-acetylglucosaminyltransferase-i","display_name":"N-acetylglucosaminyltransferase I","score":0.9900000095367432},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.9210000038146973},{"id":"https://openalex.org/keywords/complex-n-glycans","display_name":"complex N-glycans","score":0.9039999842643738},{"id":"https://openalex.org/keywords/n-glycosylation-sites","display_name":"N-glycosylation sites","score":0.8029999732971191},{"id":"https://openalex.org/keywords/golgi-enzymes","display_name":"Golgi enzymes","score":0.5550000071525574},{"id":"https://openalex.org/keywords/enzyme-folding","display_name":"enzyme folding","score":0.6119999885559082},{"id":"https://openalex.org/keywords/n-glycan-processing","display_name":"N-glycan processing","score":0.7229999899864197},{"id":"https://openalex.org/keywords/heterologous-expression","display_name":"heterologous expression","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.6802205443382263},{"id":"https://openalex.org/C2777313579","wikidata":"https://www.wikidata.org/wiki/Q898365","display_name":"Glycosylation","level":2,"score":0.6029731035232544},{"id":"https://openalex.org/C30324644","wikidata":"https://www.wikidata.org/wiki/Q3334151","display_name":"N-linked glycosylation","level":4,"score":0.593345582485199},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5791837573051453},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5504931211471558},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.5493341684341431},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5436349511146545},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.4678785502910614},{"id":"https://openalex.org/C158619295","wikidata":"https://www.wikidata.org/wiki/Q21101062","display_name":"Endoplasmic-reticulum-associated protein degradation","level":4,"score":0.467096745967865},{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.43121716380119324},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.21223744750022888},{"id":"https://openalex.org/C139447449","wikidata":"https://www.wikidata.org/wiki/Q14633900","display_name":"Unfolded protein response","level":3,"score":0.18243619799613953},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.15664425492286682},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15385988354682922}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017351","descriptor_name":"N-Acetylglucosaminyltransferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017351","descriptor_name":"N-Acetylglucosaminyltransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1042/bj20041686","doi":"https://doi.org/10.1042/bj20041686","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj20041686","pdf_url":"https://portlandpress.com/biochemj/article-pdf/387/2/385/720226/bj3870385.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},{"id":"pmid:15537386","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15537386","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Biochemical journal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1134966","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1134966/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochem J","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1042/bj20041686","doi":"https://doi.org/10.1042/bj20041686","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj20041686","pdf_url":"https://portlandpress.com/biochemj/article-pdf/387/2/385/720226/bj3870385.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5390844734","display_name":"The catalytic mechanism of UDP-GlcNAc: Mannoside N-acetylglucosamintransferases I and II","funder_award_id":"P14343","funder_id":"https://openalex.org/F4320321181","funder_display_name":"Austrian Science Fund"}],"funders":[{"id":"https://openalex.org/F4320321181","display_name":"Austrian Science Fund","ror":"https://ror.org/013tf3c58"},{"id":"https://openalex.org/F4320323821","display_name":"Universit\u00e4t f\u00fcr Bodenkultur Wien","ror":"https://ror.org/057ff4y42"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2073039121.pdf","grobid_xml":"https://content.openalex.org/works/W2073039121.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W142220879","https://openalex.org/W248961844","https://openalex.org/W1482931197","https://openalex.org/W1532050252","https://openalex.org/W1546157935","https://openalex.org/W1639179179","https://openalex.org/W1776136637","https://openalex.org/W1875959162","https://openalex.org/W1966887838","https://openalex.org/W1977937848","https://openalex.org/W1990976236","https://openalex.org/W1999063456","https://openalex.org/W2011006472","https://openalex.org/W2022408153","https://openalex.org/W2024556021","https://openalex.org/W2074827684","https://openalex.org/W2076452068","https://openalex.org/W2079531717","https://openalex.org/W2084694430","https://openalex.org/W2099258810","https://openalex.org/W2107491970","https://openalex.org/W2116122104","https://openalex.org/W2133912554","https://openalex.org/W2135931409","https://openalex.org/W2140273488","https://openalex.org/W2146804547","https://openalex.org/W2152708819","https://openalex.org/W2154125835","https://openalex.org/W2157319606","https://openalex.org/W2159050517","https://openalex.org/W2169499352","https://openalex.org/W4243001760","https://openalex.org/W4244331995","https://openalex.org/W4296322132","https://openalex.org/W6632684027","https://openalex.org/W6680647856"],"related_works":["https://openalex.org/W7097028648","https://openalex.org/W2105456078","https://openalex.org/W2079531717","https://openalex.org/W2084694430","https://openalex.org/W2135931409","https://openalex.org/W2132372019","https://openalex.org/W2159050517","https://openalex.org/W2754083730","https://openalex.org/W2099258810","https://openalex.org/W66185224"],"abstract_inverted_index":{"GnTI":[0,24,37,61,114,132],"(N-acetylglucosaminyltransferase":[1],"I)":[2],"is":[3,137],"a":[4,28,40,45,94,100],"Golgi-resident":[5],"enzyme":[6],"essential":[7],"for":[8],"the":[9,71,74,80,91,128,141,149,153],"processing":[10],"of":[11,35,59,68,73,79,93,111,131,152],"high-mannose":[12],"to":[13,99,140,146],"hybrid":[14],"and":[15,26,70],"complex":[16,121],"N-glycans.":[17],"The":[18],"Arabidopsis":[19],"thaliana":[20],"cgl":[21,36,60,116,135],"mutant":[22],"lacks":[23],"activity":[25,69,133],"as":[27],"consequence":[29],"accumulates":[30],"oligomannosidic":[31],"structures.":[32],"Molecular":[33],"cloning":[34],"cDNA":[38],"revealed":[39],"point":[41],"mutation,":[42],"which":[43,86,144],"causes":[44],"critical":[46],"amino":[47],"acid":[48],"substitution":[49],"(Asp144-->Asn),":[50],"thereby":[51],"creating":[52],"an":[53],"additional":[54,142],"N-glycosylation":[55,75,96],"site.":[56,76],"Heterologous":[57],"expression":[58],"in":[62,90,115,134],"insect":[63],"cells":[64],"confirmed":[65],"its":[66],"lack":[67],"use":[72],"Remarkably,":[77],"introduction":[78],"Asp144-->Asn":[81],"mutation":[82],"into":[83],"rabbit":[84,113],"GnTI,":[85],"does":[87],"not":[88],"result":[89],"formation":[92],"new":[95],"site,":[97],"led":[98],"protein":[101],"with":[102,148],"strongly":[103],"reduced,":[104],"but":[105],"still":[106],"detectable":[107],"enzymic":[108],"activity.":[109],"Expression":[110],"Asn144":[112],"plants":[117,136],"could":[118],"partially":[119],"restore":[120],"N-glycan":[122],"formation.":[123],"These":[124],"results":[125],"indicate":[126],"that":[127],"complete":[129],"deficiency":[130],"mainly":[138],"due":[139],"N-glycan,":[143],"appears":[145],"interfere":[147],"proper":[150],"folding":[151],"enzyme.":[154]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}