{"id":"https://openalex.org/W2072968038","doi":"https://doi.org/10.1158/1538-7445.am2013-869","title":"Abstract 869: PTEN/PI3K oncogenic pathway profiling informs an in vivo synergistic therapeutic model for basal-like breast cancer.","display_name":"Abstract 869: PTEN/PI3K oncogenic pathway profiling informs an in vivo synergistic therapeutic model for basal-like breast cancer.","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W2072968038","doi":"https://doi.org/10.1158/1538-7445.am2013-869","mag":"2072968038"},"language":"en","primary_location":{"id":"doi:10.1158/1538-7445.am2013-869","doi":"https://doi.org/10.1158/1538-7445.am2013-869","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2013-869","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016805282","display_name":"Lao H. Saal","orcid":"https://orcid.org/0000-0002-0815-1896","observed_orcids":["https://orcid.org/0000-0002-0815-1896"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lao H. Saal","raw_affiliation_strings":["1Lund University, Lund, Sweden;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Lund University, Lund, Sweden;","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074806052","display_name":"Qing\u2010Bai She","orcid":"https://orcid.org/0000-0002-7207-0599","observed_orcids":["https://orcid.org/0000-0002-7207-0599"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qing-Bai She","raw_affiliation_strings":["2Memorial Sloan-Kettering Cancer Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Memorial Sloan-Kettering Cancer Center, New York, NY;","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085251030","display_name":"Sofia K. Gruvberger-Saal","orcid":"https://orcid.org/0000-0002-8478-9920","observed_orcids":["https://orcid.org/0000-0002-8478-9920"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Sofia K. Gruvberger-Saal","raw_affiliation_strings":["1Lund University, Lund, Sweden;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Lund University, Lund, Sweden;","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111661839","display_name":"Matthew S. Maurer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Maurer","raw_affiliation_strings":["3Columbia University, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Columbia University, New York, NY;","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035955930","display_name":"Mervi Jumppanen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144379","display_name":"Sein\u00e4joen Keskussairaala","ror":"https://ror.org/0398vrq41","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210144379"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Mervi Jumppanen","raw_affiliation_strings":["4Seina\u0308joki Central Hospital, Seina\u0308joki, Finland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Seina\u0308joki Central Hospital, Seina\u0308joki, Finland;","institution_ids":["https://openalex.org/I4210144379"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101448723","display_name":"Tao Su","orcid":"https://orcid.org/0000-0001-8672-9166","observed_orcids":["https://orcid.org/0000-0001-8672-9166"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tao Su","raw_affiliation_strings":["3Columbia University, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Columbia University, New York, NY;","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049508551","display_name":"Meaghan Dendy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Meaghan Dendy","raw_affiliation_strings":["3Columbia University, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Columbia University, New York, NY;","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110347221","display_name":"Ying-Ka Ingar Lau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ying-Ka I. Lau","raw_affiliation_strings":["3Columbia University, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Columbia University, New York, NY;","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011578131","display_name":"Lorenzo Memeo","orcid":"https://orcid.org/0000-0003-4251-7203","observed_orcids":["https://orcid.org/0000-0003-4251-7203"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lorenzo Memeo","raw_affiliation_strings":["3Columbia University, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Columbia University, New York, NY;","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028075419","display_name":"Markus Ringn\u00e9r","orcid":"https://orcid.org/0000-0001-5469-8940","observed_orcids":["https://orcid.org/0000-0001-5469-8940"]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Markus Ringner","raw_affiliation_strings":["1Lund University, Lund, Sweden;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Lund University, Lund, Sweden;","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068108014","display_name":"Jorma J Isola","orcid":"https://orcid.org/0000-0002-0849-5939","observed_orcids":["https://orcid.org/0000-0002-0849-5939"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Jorma Isola","raw_affiliation_strings":["5University of Tampere, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5University of Tampere, Tampere, Finland","institution_ids":["https://openalex.org/I166825849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084696219","display_name":"Hanina H. Hibshoosh","orcid":"https://orcid.org/0000-0001-9688-4514","observed_orcids":["https://orcid.org/0000-0001-9688-4514"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hanina Hibshoosh","raw_affiliation_strings":["3Columbia University, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Columbia University, New York, NY;","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060228803","display_name":"Neal X. Rosen","orcid":"https://orcid.org/0000-0002-8307-654X","observed_orcids":["https://orcid.org/0000-0002-8307-654X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neal Rosen","raw_affiliation_strings":["2Memorial Sloan-Kettering Cancer Center, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Memorial Sloan-Kettering Cancer Center, New York, NY;","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082690187","display_name":"Ramon E. Parsons","orcid":"https://orcid.org/0000-0002-6656-3514","observed_orcids":["https://orcid.org/0000-0002-6656-3514"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramon Parsons","raw_affiliation_strings":["3Columbia University, New York, NY;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Columbia University, New York, NY;","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"73","issue":"8_Supplement","first_page":"869","last_page":"869"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.7788000106811523,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.7788000106811523,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.2102999985218048,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12829","display_name":"Advanced Breast Cancer Therapies","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/basal-like-breast-cancer","display_name":"basal-like breast cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pten","display_name":"PTEN","score":0.8949999809265137},{"id":"https://openalex.org/keywords/pi3k-signaling","display_name":"PI3K signaling","score":0.9470000267028809},{"id":"https://openalex.org/keywords/egfr","display_name":"EGFR","score":0.7419999837875366},{"id":"https://openalex.org/keywords/pik3ca","display_name":"PIK3CA","score":0.9110000133514404},{"id":"https://openalex.org/keywords/tp53-mutation","display_name":"TP53 mutation","score":0.6840000152587891},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.5220000147819519},{"id":"https://openalex.org/keywords/gefitinib","display_name":"gefitinib","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pi3k-inhibitors","display_name":"PI3K inhibitors","score":0.8209999799728394},{"id":"https://openalex.org/keywords/ly294002","display_name":"LY294002","score":0.9430000185966492},{"id":"https://openalex.org/keywords/estrogen-receptor-negative-tumors","display_name":"estrogen receptor-negative tumors","score":0.7110000252723694},{"id":"https://openalex.org/keywords/therapeutic-synergy","display_name":"therapeutic synergy","score":0.5519999861717224},{"id":"https://openalex.org/keywords/xenograft-models","display_name":"xenograft models","score":0.8489999771118164},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8989999890327454},{"id":"https://openalex.org/keywords/molecular-alterations","display_name":"molecular alterations","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C2777609662","wikidata":"https://www.wikidata.org/wiki/Q416356","display_name":"PTEN","level":4,"score":0.9023481011390686},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.6720479726791382},{"id":"https://openalex.org/C2780580887","wikidata":"https://www.wikidata.org/wiki/Q417824","display_name":"Gefitinib","level":4,"score":0.6653786897659302},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6594833135604858},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.509330153465271},{"id":"https://openalex.org/C2779012181","wikidata":"https://www.wikidata.org/wiki/Q2750567","display_name":"Cytokeratin","level":3,"score":0.45742711424827576},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.44935983419418335},{"id":"https://openalex.org/C84606932","wikidata":"https://www.wikidata.org/wiki/Q416496","display_name":"Estrogen receptor","level":4,"score":0.4196210205554962},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3801043927669525},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3404502868652344},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.33693885803222656},{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.2972913980484009},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.29164832830429077},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28842270374298096},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.2651616632938385},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.1293395459651947},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1538-7445.am2013-869","doi":"https://doi.org/10.1158/1538-7445.am2013-869","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1538-7445.am2013-869","pdf_url":null,"source":{"id":"https://openalex.org/S168522863","display_name":"Cancer Research","issn_l":"0008-5472","issn":["0008-5472","1538-7445"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2480418441","https://openalex.org/W2142577868","https://openalex.org/W6977393075","https://openalex.org/W2148823465","https://openalex.org/W2171564712","https://openalex.org/W2126506845","https://openalex.org/W6902567775","https://openalex.org/W2048991577","https://openalex.org/W2106036365","https://openalex.org/W2073308507"],"abstract_inverted_index":{"Abstract":[0],"The":[1,35],"basal-like":[2,40,250],"breast":[3,60,251],"cancer":[4],"(BBC)":[5],"subtype":[6,129],"is":[7],"generally":[8],"characterized":[9],"by":[10,130],"positive":[11],"staining":[12],"for":[13,119,200,249,265],"basal":[14],"mammary":[15],"epithelial":[16],"cytokeratin":[17,123],"markers,":[18],"lack":[19],"of":[20,50,66,82,90,104,110,194,203,256,261],"hormone":[21],"receptor":[22,84],"and":[23,26,125,145,165,196],"HER2":[24],"expression,":[25],"poor":[27],"prognosis":[28],"with":[29,156],"currently":[30],"no":[31],"approved":[32],"molecularly-targeted":[33],"therapies.":[34],"oncogenic":[36,71,239],"signaling":[37],"pathways":[38,147],"driving":[39],"tumorigenesis,":[41],"however,":[42],"are":[43],"not":[44],"fully":[45],"elucidated.":[46],"In":[47,150],"an":[48,170,243],"analysis":[49],"phosphoinositide":[51],"3-kinase":[52],"(PI3K)":[53],"pathway-activating":[54],"molecular":[55,128],"aberrations":[56],"in":[57,148,169,171,244],"116":[58],"unselected":[59],"tumors,":[61],"we":[62],"find":[63],"that":[64],"three-quarters":[65],"cases":[67],"had":[68,100],"a":[69,138],"potential":[70,139],"alteration":[72],"to":[73,88,115],"PIK3CA,":[74],"PTEN,":[75],"HER2,":[76],"INPP4B,":[77],"or":[78,102],"EGFR,":[79],"including":[80],"97%":[81],"estrogen":[83],"(ER)-negative":[85],"tumors":[86,92,99],"compared":[87],"65%":[89],"ER-positive":[91],"(P<0.001).":[93],"Interestingly,":[94],"nearly":[95],"all":[96],"p53":[97],"mutant":[98],"one":[101],"more":[103,182],"these":[105],"alterations":[106],"(93%,":[107],"P=0.001).":[108],"Loss":[109],"PTEN":[111],"was":[112,163,181],"significantly":[113],"associated":[114],"EGFR":[116,146,195],"overexpression,":[117],"positivity":[118],"the":[120,126,143,157,190,201,257,262],"BBC":[121,127,151,173],"marker":[122],"5/14,":[124],"mRNA":[131],"gene":[132],"expression":[133],"profiling":[134,241],"(all":[135],"P<0.001),":[136],"informing":[137],"therapeutic":[140,247],"combination":[141,154],"targeting":[142],"PTEN/PI3K":[144,238],"BBC.":[149,204],"cell":[152],"lines,":[153],"treatment":[155,202],"EGFR-inhibitor":[158],"gefitinib":[159,177],"plus":[160,178],"PI3K-inhibitor":[161,179],"LY294002":[162],"synergistic":[164,246],"increased":[166],"apoptosis.":[167],"Similarly,":[168],"vivo":[172,245],"xenograft":[174],"mouse":[175],"model,":[176],"PWT-458":[180],"effective":[183],"than":[184],"either":[185],"monotherapy.":[186],"Our":[187],"study":[188],"supports":[189],"future":[191],"clinical":[192],"evaluation":[193],"PI3K":[197],"pathway":[198,240],"inhibitors":[199],"Citation":[205],"Format:":[206],"Lao":[207],"H.":[208],"Saal,":[209],"Qing-Bai":[210],"She,":[211],"Sofia":[212],"K.":[213],"Gruvberger-Saal,":[214],"Matthew":[215],"Maurer,":[216],"Mervi":[217],"Jumppanen,":[218],"Tao":[219],"Su,":[220],"Meaghan":[221],"Dendy,":[222],"Ying-Ka":[223],"I.":[224],"Lau,":[225],"Lorenzo":[226],"Memeo,":[227],"Markus":[228],"Ringner,":[229],"Jorma":[230],"Isola,":[231],"Hanina":[232],"Hibshoosh,":[233],"Neal":[234],"Rosen,":[235],"Ramon":[236],"Parsons.":[237],"informs":[242],"model":[248],"cancer.":[252],"[abstract].":[253],"In:":[254],"Proceedings":[255],"104th":[258],"Annual":[259],"Meeting":[260],"American":[263],"Association":[264],"Cancer":[266,276],"Research;":[267],"2013":[268],"Apr":[269],"6-10;":[270],"Washington,":[271],"DC.":[272],"Philadelphia":[273],"(PA):":[274],"AACR;":[275],"Res":[277],"2013;73(8":[278],"Suppl):Abstract":[279],"nr":[280],"869.":[281],"doi:10.1158/1538-7445.AM2013-869":[282]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}