{"id":"https://openalex.org/W2072609727","doi":"https://doi.org/10.5152/balkanmedj.2012.079","title":"Aquaporin-1 and Aquaporin-3 Expressions in the Intervertebral Disc of Rats with Aging","display_name":"Aquaporin-1 and Aquaporin-3 Expressions in the Intervertebral Disc of Rats with Aging","publication_year":2012,"publication_date":"2012-08-23","ids":{"openalex":"https://openalex.org/W2072609727","doi":"https://doi.org/10.5152/balkanmedj.2012.079","mag":"2072609727","pmid":"https://pubmed.ncbi.nlm.nih.gov/25207032","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4115877"},"language":"en","primary_location":{"id":"doi:10.5152/balkanmedj.2012.079","doi":"https://doi.org/10.5152/balkanmedj.2012.079","is_oa":true,"landing_page_url":"https://doi.org/10.5152/balkanmedj.2012.079","pdf_url":"https://doi.org/10.5152/balkanmedj.2012.079","source":{"id":"https://openalex.org/S2479243684","display_name":"Balkan Medical Journal","issn_l":"1301-3149","issn":["1301-3149","2146-3123","2146-3131"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Balkan Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.5152/balkanmedj.2012.079","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113924763","display_name":"Ufuk Ta\u015f","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I238144855","display_name":"Tokat Gaziosmanpa\u015fa \u00dcniversitesi","ror":"https://ror.org/01rpe9k96","country_code":"TR","type":"education","lineage":["https://openalex.org/I238144855"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ufuk Tas","raw_affiliation_strings":["Department of Anatomy, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey","Department of Anatomy Faculty of Medicine Gaziosmanpasa University Tokat Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey","institution_ids":["https://openalex.org/I238144855"]},{"raw_affiliation_string":"Department of Anatomy Faculty of Medicine Gaziosmanpasa University Tokat Turkey","institution_ids":["https://openalex.org/I238144855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050328648","display_name":"Sevil \u00c7ayl\u0131","orcid":"https://orcid.org/0000-0003-2465-5389","observed_orcids":["https://orcid.org/0000-0003-2465-5389"]},"institutions":[{"id":"https://openalex.org/I238144855","display_name":"Tokat Gaziosmanpa\u015fa \u00dcniversitesi","ror":"https://ror.org/01rpe9k96","country_code":"TR","type":"education","lineage":["https://openalex.org/I238144855"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Sevil Cayli","raw_affiliation_strings":["Department of Histology and Embryology, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey;","institution_ids":["https://openalex.org/I238144855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036860510","display_name":"Ahmet \u0130nan\u0131r","orcid":"https://orcid.org/0000-0001-8300-2682","observed_orcids":["https://orcid.org/0000-0001-8300-2682"]},"institutions":[{"id":"https://openalex.org/I238144855","display_name":"Tokat Gaziosmanpa\u015fa \u00dcniversitesi","ror":"https://ror.org/01rpe9k96","country_code":"TR","type":"education","lineage":["https://openalex.org/I238144855"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ahmet Inanir","raw_affiliation_strings":["Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey","institution_ids":["https://openalex.org/I238144855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050785734","display_name":"Birsen \u00d6zyurt","orcid":"https://orcid.org/0000-0002-7421-9246","observed_orcids":["https://orcid.org/0000-0002-7421-9246"]},"institutions":[{"id":"https://openalex.org/I238144855","display_name":"Tokat Gaziosmanpa\u015fa \u00dcniversitesi","ror":"https://ror.org/01rpe9k96","country_code":"TR","type":"education","lineage":["https://openalex.org/I238144855"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Birsen Ozyurt","raw_affiliation_strings":["Department of Anatomy, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey","Department of Anatomy Faculty of Medicine Gaziosmanpasa University Tokat Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey","institution_ids":["https://openalex.org/I238144855"]},{"raw_affiliation_string":"Department of Anatomy Faculty of Medicine Gaziosmanpasa University Tokat Turkey","institution_ids":["https://openalex.org/I238144855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070000447","display_name":"Seda Ocakl\u0131","orcid":"https://orcid.org/0000-0003-3053-281X","observed_orcids":["https://orcid.org/0000-0003-3053-281X"]},"institutions":[{"id":"https://openalex.org/I238144855","display_name":"Tokat Gaziosmanpa\u015fa \u00dcniversitesi","ror":"https://ror.org/01rpe9k96","country_code":"TR","type":"education","lineage":["https://openalex.org/I238144855"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Seda Ocakli","raw_affiliation_strings":["Department of Histology and Embryology, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey;","institution_ids":["https://openalex.org/I238144855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036491202","display_name":"Zafer Karaca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I238144855","display_name":"Tokat Gaziosmanpa\u015fa \u00dcniversitesi","ror":"https://ror.org/01rpe9k96","country_code":"TR","type":"education","lineage":["https://openalex.org/I238144855"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Zafer Ismail Karaca","raw_affiliation_strings":["Department of Histology and Embryology, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Histology and Embryology, Faculty of Medicine, Gaziosmanpa\u015fa University, Tokat, Turkey","institution_ids":["https://openalex.org/I238144855"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047740699","display_name":"Mustafa Sars\u0131lmaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I334480368","display_name":"\u015eifa University","ror":"https://ror.org/03gdf8x58","country_code":"TR","type":"education","lineage":["https://openalex.org/I334480368"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mustafa Sarsilmaz","raw_affiliation_strings":["Department of Anatomy, Faculty of Medicine, \u015eifa University; \u0130zmir-Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Faculty of Medicine, \u015eifa University; \u0130zmir-Turkey","institution_ids":["https://openalex.org/I334480368"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2303,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.61797372,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"29","issue":"4","first_page":"349","last_page":"353"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aquaporin-1","display_name":"aquaporin-1","score":0.9900000095367432},{"id":"https://openalex.org/keywords/aquaporin-3","display_name":"AQP3","score":1.0},{"id":"https://openalex.org/keywords/intervertebral-disc-degeneration","display_name":"intervertebral disc degeneration","score":0.9660000205039978},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.9490000009536743},{"id":"https://openalex.org/keywords/nucleus-pulposus","display_name":"nucleus pulposus","score":0.9660000205039978},{"id":"https://openalex.org/keywords/annulus-fibrosus","display_name":"annulus fibrosus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/water-channel-proteins","display_name":"water channel proteins","score":0.9509999752044678},{"id":"https://openalex.org/keywords/lumbar-disc","display_name":"lumbar intervertebral disc","score":0.847000002861023},{"id":"https://openalex.org/keywords/age-related-disc-degeneration","display_name":"age-related disc degeneration","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C2777755357","wikidata":"https://www.wikidata.org/wiki/Q502781","display_name":"Intervertebral disc","level":2,"score":0.8527504205703735},{"id":"https://openalex.org/C154280991","wikidata":"https://www.wikidata.org/wiki/Q623090","display_name":"Aquaporin","level":2,"score":0.8118983507156372},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.7473288178443909},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.5997174978256226},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5718168020248413},{"id":"https://openalex.org/C2779354088","wikidata":"https://www.wikidata.org/wiki/Q15467261","display_name":"Degeneration (medical)","level":2,"score":0.5715933442115784},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5352225303649902},{"id":"https://openalex.org/C177586851","wikidata":"https://www.wikidata.org/wiki/Q14905238","display_name":"Aquaporin 1","level":4,"score":0.46482375264167786},{"id":"https://openalex.org/C15755913","wikidata":"https://www.wikidata.org/wiki/Q14902502","display_name":"Aquaporin 4","level":2,"score":0.4552047550678253},{"id":"https://openalex.org/C3018239782","wikidata":"https://www.wikidata.org/wiki/Q502781","display_name":"Intervertebral disk","level":3,"score":0.45434898138046265},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.4184378981590271},{"id":"https://openalex.org/C2775845273","wikidata":"https://www.wikidata.org/wiki/Q7973466","display_name":"Water channel","level":3,"score":0.27280956506729126},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.08437100052833557},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C201289731","wikidata":"https://www.wikidata.org/wiki/Q1172599","display_name":"Inlet","level":2,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.5152/balkanmedj.2012.079","doi":"https://doi.org/10.5152/balkanmedj.2012.079","is_oa":true,"landing_page_url":"https://doi.org/10.5152/balkanmedj.2012.079","pdf_url":"https://doi.org/10.5152/balkanmedj.2012.079","source":{"id":"https://openalex.org/S2479243684","display_name":"Balkan Medical Journal","issn_l":"1301-3149","issn":["1301-3149","2146-3123","2146-3131"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Balkan Medical Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4115877","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4115877","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Balkan Med J","raw_type":"Text"},{"id":"pmid:25207032","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25207032","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Balkan medical journal","raw_type":"Journal Article"},{"id":"pmh:53a0d0ac-f360-4af1-97f1-f16492c5fcaa","doi":null,"is_oa":true,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/53a0d0ac-f360-4af1-97f1-f16492c5fcaa/oai","pdf_url":"https://avesis.aybu.edu.tr/publication/details/53a0d0ac-f360-4af1-97f1-f16492c5fcaa/oai/document.pdf","source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dergipark.gov.tr:article/50337","doi":null,"is_oa":false,"landing_page_url":"http://dergipark.gov.tr/bmj/issue/3775/50337","pdf_url":null,"source":{"id":"https://openalex.org/S4306401840","display_name":"DergiPark (Istanbul University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67581229","host_organization_name":"Istanbul University","host_organization_lineage":["https://openalex.org/I67581229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\\n Volume: 2012, Issue: 4\\n 354-357\\n \\n","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:a8dbc949037b48a38d7eb5d43ffc5ead","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/a8dbc949037b48a38d7eb5d43ffc5ead","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Balkan Medical Journal, Vol 29, Iss 4, Pp 349-353 (2012)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.5152/balkanmedj.2012.079","doi":"https://doi.org/10.5152/balkanmedj.2012.079","is_oa":true,"landing_page_url":"https://doi.org/10.5152/balkanmedj.2012.079","pdf_url":"https://doi.org/10.5152/balkanmedj.2012.079","source":{"id":"https://openalex.org/S2479243684","display_name":"Balkan Medical Journal","issn_l":"1301-3149","issn":["1301-3149","2146-3123","2146-3131"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Balkan Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2072609727.pdf","grobid_xml":"https://content.openalex.org/works/W2072609727.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W174720216","https://openalex.org/W1930491343","https://openalex.org/W1968535715","https://openalex.org/W1972211185","https://openalex.org/W1982324672","https://openalex.org/W1982680776","https://openalex.org/W1985713820","https://openalex.org/W1999776567","https://openalex.org/W2039388180","https://openalex.org/W2040349733","https://openalex.org/W2040725197","https://openalex.org/W2051039788","https://openalex.org/W2051152599","https://openalex.org/W2055676578","https://openalex.org/W2057722514","https://openalex.org/W2060910799","https://openalex.org/W2074690643","https://openalex.org/W2077492163","https://openalex.org/W2079117822","https://openalex.org/W2080670277","https://openalex.org/W2090823918","https://openalex.org/W2124862797","https://openalex.org/W6805552365"],"related_works":["https://openalex.org/W2922292398","https://openalex.org/W7215362854","https://openalex.org/W6949173921","https://openalex.org/W2372502660","https://openalex.org/W2324124890","https://openalex.org/W2620527463","https://openalex.org/W2000990372","https://openalex.org/W2365114912","https://openalex.org/W2744307430","https://openalex.org/W3016905655"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1,114,135],"intervertebral":[2,93,136,195],"disc":[3,53,137],"(IVD)":[4],"undergoes":[5],"biochemical":[6],"and":[7,28,34,80,98,154,162,169,184],"morphologic":[8],"degenerative":[9],"changes":[10],"during":[11],"the":[12,41,48,63,75,112,125,132,141,176,189,194],"process":[13],"of":[14,21,44,47,65,69,77,90,152,171,193],"aging.":[15],"Aquaporins":[16],"(AQPs)":[17],"are":[18],"a":[19,37],"family":[20],"water":[22,27],"channel":[23],"proteins":[24],"that":[25,160,182],"facilitate":[26],"small":[29],"solute":[30],"movement":[31],"in":[32,40,51,82,111,167],"tissues":[33,138],"may":[35,186],"have":[36],"potential":[38],"role":[39],"aging":[42],"degeneration":[43,54,192],"IVDs.":[45,66],"One":[46],"important":[49],"problems":[50],"understanding":[52],"is":[55],"to":[56,62,73,175,188],"find":[57],"cellular":[58],"molecules":[59],"which":[60],"contribute":[61,187],"pathogenesis":[64],"XThe":[67],"aim":[68],"this":[70],"study":[71,158],"was":[72],"demonstrate":[74],"expression":[76],"aquaporin":[78],"1":[79],"3":[81,185],"nucleus":[83],"pulposus":[84],"(NP),":[85],"annulus":[86],"fibrosus":[87],"(AF)":[88],"cells":[89],"rat":[91],"lumbar":[92,142],"discs":[94],"from":[95,140],"both":[96],"young":[97,126,177],"aged":[99,172],"animals":[100],"using":[101],"immunohistochemistry.":[102],"MATERIAL":[103],"AND":[104],"METHODS:":[105],"Twenty":[106],"Wistar-albino":[107],"rats":[108,115,122,129,173],"were":[109,116,147],"included":[110],"study.":[113],"separated":[117],"into":[118],"two":[119],"groups:":[120],"2-month-old":[121],"(n=10)":[123,130],"as":[124,131],"group,":[127],"18-month-old":[128],"old":[133],"group.":[134],"obtained":[139],"spine":[143],"(L1-L4,":[144],"4":[145],"discs)":[146],"used":[148],"for":[149],"immunohistochemical":[150],"staining":[151],"AQP-1":[153,161,183],"3.":[155],"RESULTS:":[156],"This":[157],"demonstrated":[159],"AQP-3":[163],"immunoreactivity":[164],"significantly":[165],"decreased":[166],"NP":[168],"AF":[170],"compared":[174],"rats.":[178],"CONCLUSION:":[179],"We":[180],"suggest":[181],"age":[190],"related":[191],"disc.":[196]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}