{"id":"https://openalex.org/W2072392983","doi":"https://doi.org/10.1016/j.clon.2006.02.008","title":"Symptomatic Responses to Neoadjuvant Chemotherapy for Carcinoma of the Oesophagus and Oesophagogastric Junction: Are They Worth Measuring?","display_name":"Symptomatic Responses to Neoadjuvant Chemotherapy for Carcinoma of the Oesophagus and Oesophagogastric Junction: Are They Worth Measuring?","publication_year":2006,"publication_date":"2006-03-28","ids":{"openalex":"https://openalex.org/W2072392983","doi":"https://doi.org/10.1016/j.clon.2006.02.008","mag":"2072392983","pmid":"https://pubmed.ncbi.nlm.nih.gov/16703754"},"language":"en","primary_location":{"id":"doi:10.1016/j.clon.2006.02.008","doi":"https://doi.org/10.1016/j.clon.2006.02.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clon.2006.02.008","pdf_url":null,"source":{"id":"https://openalex.org/S190064913","display_name":"Clinical Oncology","issn_l":"0936-6555","issn":["0936-6555","1433-2981"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012126642","display_name":"M Forshaw","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1298207432","display_name":"Guy's Hospital","ror":"https://ror.org/04r33pf22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1298207432","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I1324925910","display_name":"St Thomas' Hospital","ror":"https://ror.org/054gk2851","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324925910","https://openalex.org/I200166805","https://openalex.org/I4210111135"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M.J. Forshaw","raw_affiliation_strings":["Department of General Surgery, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK","Department of General Surgery, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK","institution_ids":["https://openalex.org/I1298207432","https://openalex.org/I1324925910"]},{"raw_affiliation_string":"Department of General Surgery, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052291824","display_name":"James Gossage","orcid":"https://orcid.org/0000-0002-1185-8059","observed_orcids":["https://orcid.org/0000-0002-1185-8059"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.A. Gossage","raw_affiliation_strings":["Department of General Surgery, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057369891","display_name":"Kathryn F. Chrystal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1298207432","display_name":"Guy's Hospital","ror":"https://ror.org/04r33pf22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1298207432","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I1324925910","display_name":"St Thomas' Hospital","ror":"https://ror.org/054gk2851","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324925910","https://openalex.org/I200166805","https://openalex.org/I4210111135"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K. Chrystal","raw_affiliation_strings":["Department of Medical Oncology, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK","institution_ids":["https://openalex.org/I1298207432","https://openalex.org/I1324925910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111641971","display_name":"K. Cheong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1298207432","display_name":"Guy's Hospital","ror":"https://ror.org/04r33pf22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1298207432","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I1324925910","display_name":"St Thomas' Hospital","ror":"https://ror.org/054gk2851","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324925910","https://openalex.org/I200166805","https://openalex.org/I4210111135"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K. Cheong","raw_affiliation_strings":["Department of Medical Oncology, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK","institution_ids":["https://openalex.org/I1298207432","https://openalex.org/I1324925910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101758297","display_name":"Peter Harper","orcid":"https://orcid.org/0000-0001-6754-8343","observed_orcids":["https://orcid.org/0000-0001-6754-8343"]},"institutions":[{"id":"https://openalex.org/I1298207432","display_name":"Guy's Hospital","ror":"https://ror.org/04r33pf22","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1298207432","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I1324925910","display_name":"St Thomas' Hospital","ror":"https://ror.org/054gk2851","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324925910","https://openalex.org/I200166805","https://openalex.org/I4210111135"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P.G. Harper","raw_affiliation_strings":["Department of Medical Oncology, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Guy's and St Thomas' NHS Trust, St Thomas' Hospital, London, UK","institution_ids":["https://openalex.org/I1298207432","https://openalex.org/I1324925910"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002008554","display_name":"Robert C. Mason","orcid":"https://orcid.org/0000-0002-5267-2189","observed_orcids":["https://orcid.org/0000-0002-5267-2189"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"R.C. Mason","raw_affiliation_strings":["Department of General Surgery, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, UK","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5002008554"],"corresponding_institution_ids":[],"apc_list":{"value":3200,"currency":"USD","value_usd":3200},"apc_paid":null,"fwci":0.7243,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.71829693,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"18","issue":"4","first_page":"345","last_page":"350"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11358","display_name":"Dysphagia Assessment and Management","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neoadjuvant-chemotherapy","display_name":"neoadjuvant chemotherapy","score":0.9679999947547913},{"id":"https://openalex.org/keywords/esophageal-cancer","display_name":"esophageal cancer","score":0.9070000052452087},{"id":"https://openalex.org/keywords/gastroesophageal-junction-cancer","display_name":"gastroesophageal junction cancer","score":0.9409999847412109},{"id":"https://openalex.org/keywords/epirubicin","display_name":"epirubicin","score":0.8309999704360962},{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.9829999804496765},{"id":"https://openalex.org/keywords/5-fluorouracil","display_name":"5-fluorouracil","score":0.9909999966621399},{"id":"https://openalex.org/keywords/dysphagia","display_name":"dysphagia","score":0.9179999828338623},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.9739999771118164},{"id":"https://openalex.org/keywords/chemotherapy-response-assessment","display_name":"chemotherapy response assessment","score":0.6769999861717224},{"id":"https://openalex.org/keywords/radiological-response","display_name":"radiological response","score":0.6539999842643738},{"id":"https://openalex.org/keywords/pathological-response","display_name":"pathological response","score":0.8109999895095825},{"id":"https://openalex.org/keywords/resectability","display_name":"resectability","score":0.6570000052452087},{"id":"https://openalex.org/keywords/patient-selection-for-surgery","display_name":"patient selection for surgery","score":0.7390000224113464}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9307905435562134},{"id":"https://openalex.org/C112497637","wikidata":"https://www.wikidata.org/wiki/Q211669","display_name":"Swallowing","level":2,"score":0.7465255260467529},{"id":"https://openalex.org/C2780835546","wikidata":"https://www.wikidata.org/wiki/Q425122","display_name":"Epirubicin","level":4,"score":0.6909931898117065},{"id":"https://openalex.org/C2780596822","wikidata":"https://www.wikidata.org/wiki/Q623289","display_name":"Dysphagia","level":2,"score":0.6798604726791382},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6284265518188477},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.5154936909675598},{"id":"https://openalex.org/C2778822529","wikidata":"https://www.wikidata.org/wiki/Q1951525","display_name":"Progressive disease","level":3,"score":0.5022869110107422},{"id":"https://openalex.org/C2778424827","wikidata":"https://www.wikidata.org/wiki/Q5090613","display_name":"Chemoradiotherapy","level":3,"score":0.4500735402107239},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4426642656326294},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.44182682037353516},{"id":"https://openalex.org/C2780323790","wikidata":"https://www.wikidata.org/wiki/Q2912193","display_name":"Esophageal disease","level":3,"score":0.41505351662635803},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.40840578079223633},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.39631161093711853},{"id":"https://openalex.org/C2777819096","wikidata":"https://www.wikidata.org/wiki/Q173710","display_name":"Esophagus","level":2,"score":0.16735711693763733},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.05368363857269287},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003657","descriptor_name":"Decision Making","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003679","descriptor_name":"Deglutition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D004943","descriptor_name":"Esophagogastric Junction","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005472","descriptor_name":"Fluorouracil","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015251","descriptor_name":"Epirubicin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.clon.2006.02.008","doi":"https://doi.org/10.1016/j.clon.2006.02.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clon.2006.02.008","pdf_url":null,"source":{"id":"https://openalex.org/S190064913","display_name":"Clinical Oncology","issn_l":"0936-6555","issn":["0936-6555","1433-2981"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Oncology","raw_type":"journal-article"},{"id":"pmid:16703754","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16703754","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical oncology (Royal College of Radiologists (Great Britain))","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W224697977","https://openalex.org/W1625189041","https://openalex.org/W1865426939","https://openalex.org/W1901180305","https://openalex.org/W1964067844","https://openalex.org/W1977468182","https://openalex.org/W1996433466","https://openalex.org/W1997155298","https://openalex.org/W2011698349","https://openalex.org/W2020521007","https://openalex.org/W2023086358","https://openalex.org/W2025945212","https://openalex.org/W2026949114","https://openalex.org/W2028269517","https://openalex.org/W2035240434","https://openalex.org/W2045830855","https://openalex.org/W2050057988","https://openalex.org/W2050972034","https://openalex.org/W2051298545","https://openalex.org/W2054837552","https://openalex.org/W2075362684","https://openalex.org/W2093882157","https://openalex.org/W2099972879","https://openalex.org/W2108088065","https://openalex.org/W2109603651","https://openalex.org/W2122352172","https://openalex.org/W2134506690","https://openalex.org/W2158535566","https://openalex.org/W2160019071","https://openalex.org/W2270432219","https://openalex.org/W2315843358","https://openalex.org/W2333224485","https://openalex.org/W2338880854","https://openalex.org/W2347198999","https://openalex.org/W4253667253","https://openalex.org/W4300955892"],"related_works":["https://openalex.org/W2134506690","https://openalex.org/W4402132194","https://openalex.org/W2326065612","https://openalex.org/W4223600553","https://openalex.org/W2906470118","https://openalex.org/W2149761022","https://openalex.org/W3158224073","https://openalex.org/W2590027378","https://openalex.org/W2968254700","https://openalex.org/W2887589608"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}