{"id":"https://openalex.org/W2072227092","doi":"https://doi.org/10.3109/03009742.2014.918175","title":"Relationship between SNPs and expression level for candidate genes in rheumatoid arthritis","display_name":"Relationship between SNPs and expression level for candidate genes in rheumatoid arthritis","publication_year":2014,"publication_date":"2014-09-15","ids":{"openalex":"https://openalex.org/W2072227092","doi":"https://doi.org/10.3109/03009742.2014.918175","mag":"2072227092","pmid":"https://pubmed.ncbi.nlm.nih.gov/25221852"},"language":"en","primary_location":{"id":"doi:10.3109/03009742.2014.918175","doi":"https://doi.org/10.3109/03009742.2014.918175","is_oa":false,"landing_page_url":"https://doi.org/10.3109/03009742.2014.918175","pdf_url":null,"source":{"id":"https://openalex.org/S42124886","display_name":"Scandinavian Journal of Rheumatology","issn_l":"0300-9742","issn":["0300-9742","1502-7732"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Rheumatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://dspace.library.uu.nl/handle/1874/331487","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009895966","display_name":"Mostefa Fodil","orcid":"https://orcid.org/0000-0003-2856-1988","observed_orcids":["https://orcid.org/0000-0003-2856-1988"]},"institutions":[{"id":"https://openalex.org/I3124969661","display_name":"Universit\u00e9 des Sciences et de la Technologie d'Oran Mohamed Boudiaf","ror":"https://ror.org/02nbj1r55","country_code":"DZ","type":"education","lineage":["https://openalex.org/I3124969661"]},{"id":"https://openalex.org/I4405252902","display_name":"Laboratoire de recherche europ\u00e9en pour la polyarthrite rhumato\u00efde","ror":"https://ror.org/003ene322","country_code":"FR","type":"facility","lineage":["https://openalex.org/I277688954","https://openalex.org/I4405252902","https://openalex.org/I88467170"]}],"countries":["DZ","FR"],"is_corresponding":false,"raw_author_name":"M Fodil","raw_affiliation_strings":["GenHotel-EA3886, Evry-Val d'Essonne University, Evry-Genopole, France","Department of Applied Molecular Genetics, University of Sciences and Technology of Oran Mohamed Boudiaf (USTO-MB), Oran', Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenHotel-EA3886, Evry-Val d'Essonne University, Evry-Genopole, France","institution_ids":["https://openalex.org/I4405252902"]},{"raw_affiliation_string":"Department of Applied Molecular Genetics, University of Sciences and Technology of Oran Mohamed Boudiaf (USTO-MB), Oran', Algeria","institution_ids":["https://openalex.org/I3124969661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018430261","display_name":"VH Teixeira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405252902","display_name":"Laboratoire de recherche europ\u00e9en pour la polyarthrite rhumato\u00efde","ror":"https://ror.org/003ene322","country_code":"FR","type":"facility","lineage":["https://openalex.org/I277688954","https://openalex.org/I4405252902","https://openalex.org/I88467170"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["FR","GB"],"is_corresponding":false,"raw_author_name":"VH Teixeira","raw_affiliation_strings":["GenHotel-EA3886, Evry-Val d\u2019Essonne University, Evry-Genopole, France; Centre for Respiratory Research, University College London, UK","Centre for Respiratory Research, University College London, UK","GenHotel-EA3886, Evry-Val d'Essonne University, Evry-Genopole, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenHotel-EA3886, Evry-Val d\u2019Essonne University, Evry-Genopole, France; Centre for Respiratory Research, University College London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Respiratory Research, University College London, UK","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"GenHotel-EA3886, Evry-Val d'Essonne University, Evry-Genopole, France","institution_ids":["https://openalex.org/I4405252902"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041468847","display_name":"Val\u00e9rie Chaudru","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405252902","display_name":"Laboratoire de recherche europ\u00e9en pour la polyarthrite rhumato\u00efde","ror":"https://ror.org/003ene322","country_code":"FR","type":"facility","lineage":["https://openalex.org/I277688954","https://openalex.org/I4405252902","https://openalex.org/I88467170"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"V Chaudru","raw_affiliation_strings":["GenHotel-EA3886, Evry-Val d\u2019Essonne University, Evry-Genopole, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenHotel-EA3886, Evry-Val d\u2019Essonne University, Evry-Genopole, France","institution_ids":["https://openalex.org/I4405252902"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040733842","display_name":"Pascal Hilliquin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113338","display_name":"Centre Hospitalier Sud Francilien","ror":"https://ror.org/0246mbd04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210113338"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P Hilliquin","raw_affiliation_strings":["South Francilien Hospital Centre, Corbeil-Essonnes, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South Francilien Hospital Centre, Corbeil-Essonnes, France","institution_ids":["https://openalex.org/I4210113338"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101579609","display_name":"Stefano Bombardieri","orcid":"https://orcid.org/0000-0002-3878-5216","observed_orcids":["https://orcid.org/0000-0002-3878-5216"]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S Bombardieri","raw_affiliation_strings":["University of Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054608926","display_name":"Alejandro Balsa","orcid":"https://orcid.org/0000-0001-8070-7062","observed_orcids":["https://orcid.org/0000-0001-8070-7062"]},"institutions":[{"id":"https://openalex.org/I2800562746","display_name":"Hospital Universitario La Paz","ror":"https://ror.org/01s1q0w69","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2800562746"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A Balsa","raw_affiliation_strings":["La Paz Hospital, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"La Paz Hospital, Madrid, Spain","institution_ids":["https://openalex.org/I2800562746"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110043702","display_name":"R. Westhovens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"R Westhovens","raw_affiliation_strings":["Department of Rheumatology, University of Leuven, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, University of Leuven, Belgium","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001646568","display_name":"Pilar Barrera","orcid":"https://orcid.org/0000-0003-3797-1532","observed_orcids":["https://orcid.org/0000-0003-3797-1532"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P Barrera","raw_affiliation_strings":["Nijmegen University, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nijmegen University, The Netherlands","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073709432","display_name":"Helena Alves","orcid":"https://orcid.org/0000-0001-5435-0047","observed_orcids":["https://orcid.org/0000-0001-5435-0047"]},"institutions":[{"id":"https://openalex.org/I3018176973","display_name":"Hospital de S\u00e3o Jo\u00e3o","ror":"https://ror.org/04qsnc772","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I3018176973"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"H Alves","raw_affiliation_strings":["Porto San Joao Hospital, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Porto San Joao Hospital, Portugal","institution_ids":["https://openalex.org/I3018176973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105999867","display_name":"P Migliorin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P Migliorin","raw_affiliation_strings":["University of Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008108487","display_name":"Thomas Bardin","orcid":"https://orcid.org/0000-0002-5080-4790","observed_orcids":["https://orcid.org/0000-0002-5080-4790"]},"institutions":[{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"T Bardin","raw_affiliation_strings":["Department of Rheumatology, Division of Musculoskeletal Diseases, Lariboisi\u00e8re Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Division of Musculoskeletal Diseases, Lariboisi\u00e8re Hospital, Paris, France","institution_ids":["https://openalex.org/I4210119095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108503893","display_name":"Fran\u00e7ois Corn\u00e9lis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I198244214","display_name":"Universit\u00e9 Clermont Auvergne","ror":"https://ror.org/01a8ajp46","country_code":"FR","type":"education","lineage":["https://openalex.org/I198244214"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Cornelis","raw_affiliation_strings":["GenHotel-Auvergne, CHU Clermont-Ferrand, University of Auvergne, Clermont-Ferrand, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenHotel-Auvergne, CHU Clermont-Ferrand, University of Auvergne, Clermont-Ferrand, France","institution_ids":["https://openalex.org/I198244214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008311960","display_name":"Abdallah Boudjema","orcid":"https://orcid.org/0000-0002-0319-896X","observed_orcids":["https://orcid.org/0000-0002-0319-896X"]},"institutions":[{"id":"https://openalex.org/I3124969661","display_name":"Universit\u00e9 des Sciences et de la Technologie d'Oran Mohamed Boudiaf","ror":"https://ror.org/02nbj1r55","country_code":"DZ","type":"education","lineage":["https://openalex.org/I3124969661"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"A Boudjema","raw_affiliation_strings":["Department of Applied Molecular Genetics, University of Sciences and Technology of Oran Mohamed Boudiaf (USTO-MB), Oran\u2019, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Molecular Genetics, University of Sciences and Technology of Oran Mohamed Boudiaf (USTO-MB), Oran\u2019, Algeria","institution_ids":["https://openalex.org/I3124969661"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038309467","display_name":"\u00c9lisabeth Petit","orcid":"https://orcid.org/0000-0001-9724-3575","observed_orcids":["https://orcid.org/0000-0001-9724-3575"]},"institutions":[{"id":"https://openalex.org/I4405252902","display_name":"Laboratoire de recherche europ\u00e9en pour la polyarthrite rhumato\u00efde","ror":"https://ror.org/003ene322","country_code":"FR","type":"facility","lineage":["https://openalex.org/I277688954","https://openalex.org/I4405252902","https://openalex.org/I88467170"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"E Petit-Teixeira","raw_affiliation_strings":["GenHotel-EA3886, Evry-Val d\u2019Essonne University, Evry-Genopole, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenHotel-EA3886, Evry-Val d\u2019Essonne University, Evry-Genopole, France","institution_ids":["https://openalex.org/I4405252902"]}]}],"institutions":[],"countries_distinct_count":8,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5038309467"],"corresponding_institution_ids":["https://openalex.org/I4405252902"],"apc_list":null,"apc_paid":null,"fwci":0.2594,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.59391258,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"44","issue":"1","first_page":"2","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.03519999980926514,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":1.0},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9959999918937683},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.8610000014305115},{"id":"https://openalex.org/keywords/candidate-genes","display_name":"candidate genes","score":0.8999999761581421},{"id":"https://openalex.org/keywords/rnase2","display_name":"RNASE2","score":0.9459999799728394},{"id":"https://openalex.org/keywords/pglyrp1","display_name":"PGLYRP1","score":0.9919999837875366},{"id":"https://openalex.org/keywords/s100a8","display_name":"S100A8","score":0.9580000042915344},{"id":"https://openalex.org/keywords/runx3","display_name":"RUNX3","score":0.9890000224113464},{"id":"https://openalex.org/keywords/il2rb","display_name":"IL2RB","score":0.9990000128746033},{"id":"https://openalex.org/keywords/md-2","display_name":"MD-2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/family-based-association","display_name":"family-based association","score":0.7689999938011169},{"id":"https://openalex.org/keywords/hla-drb1-shared-epitope","display_name":"HLA-DRB1 shared epitope","score":0.9760000109672546},{"id":"https://openalex.org/keywords/differential-gene-expression","display_name":"differential gene expression","score":0.6439999938011169}],"concepts":[{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.884726881980896},{"id":"https://openalex.org/C69991583","wikidata":"https://www.wikidata.org/wiki/Q1423575","display_name":"Candidate gene","level":3,"score":0.6918559074401855},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.6509092450141907},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6104552745819092},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.5450778603553772},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5151718854904175},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.514358401298523},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.4990818500518799},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4587481617927551},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3731282353401184},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.20481520891189575}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040501","descriptor_name":"Calgranulin A","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D047208","descriptor_name":"Eosinophil-Derived Neurotoxin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D050677","descriptor_name":"Core Binding Factor Alpha 3 Subunit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051218","descriptor_name":"Lymphocyte Antigen 96","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053646","descriptor_name":"Interleukin-2 Receptor beta Subunit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":10,"locations":[{"id":"doi:10.3109/03009742.2014.918175","doi":"https://doi.org/10.3109/03009742.2014.918175","is_oa":false,"landing_page_url":"https://doi.org/10.3109/03009742.2014.918175","pdf_url":null,"source":{"id":"https://openalex.org/S42124886","display_name":"Scandinavian Journal of Rheumatology","issn_l":"0300-9742","issn":["0300-9742","1502-7732"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Rheumatology","raw_type":"journal-article"},{"id":"pmid:25221852","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25221852","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian journal of rheumatology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-02084419v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-02084419","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scandinavian Journal of Rheumatology, 2015, 44 (1), pp.2--7. ⟨10.3109/03009742.2014.918175⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:arpi.unipi.it:11568/682065","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11568/682065","pdf_url":null,"source":{"id":"https://openalex.org/S4377196265","display_name":"CINECA IRIS Institutial research information system (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dspace.library.uu.nl:1874/331487","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/331487","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1545575","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1545575/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"SCANDINAVIAN JOURNAL OF RHEUMATOLOGY , 44 (1) pp. 2-7. (2015)","raw_type":"Article"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/153842","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2066/153842","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/153842","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/153842","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scandinavian Journal of Rheumatology, 44, 2 - 7","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:umcu:oai:dspace.library.uu.nl:1874/331487","doi":null,"is_oa":false,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/331487","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scandinavian Journal of Rheumatology, 44(1), 2. Informa Healthcare","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:uu:oai:dspace.library.uu.nl:1874/331487","doi":null,"is_oa":false,"landing_page_url":"http://dspace.library.uu.nl/handle/1874/331487","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scandinavian Journal of Rheumatology, 44(1), 2","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:dspace.library.uu.nl:1874/331487","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/331487","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W569951484","https://openalex.org/W1530717069","https://openalex.org/W1543868019","https://openalex.org/W1803375514","https://openalex.org/W1964349500","https://openalex.org/W1974555103","https://openalex.org/W1984939442","https://openalex.org/W1993442297","https://openalex.org/W2002036523","https://openalex.org/W2006824342","https://openalex.org/W2028331369","https://openalex.org/W2038951548","https://openalex.org/W2047306218","https://openalex.org/W2062515846","https://openalex.org/W2065419533","https://openalex.org/W2080817427","https://openalex.org/W2083277002","https://openalex.org/W2097128560","https://openalex.org/W2099174981","https://openalex.org/W2100382163","https://openalex.org/W2104982663","https://openalex.org/W2115783720","https://openalex.org/W2117626181","https://openalex.org/W2136737474","https://openalex.org/W2144082759","https://openalex.org/W2148668599","https://openalex.org/W2152348310","https://openalex.org/W2170000318","https://openalex.org/W2171500346","https://openalex.org/W2326307508","https://openalex.org/W2391458699"],"related_works":["https://openalex.org/W4240385728","https://openalex.org/W6939826333","https://openalex.org/W4385345541","https://openalex.org/W2378366146","https://openalex.org/W2984393077","https://openalex.org/W2030008043","https://openalex.org/W2059063061","https://openalex.org/W4366775590","https://openalex.org/W6986744920","https://openalex.org/W4413765336"],"abstract_inverted_index":{"OBJECTIVES:":[0],"The":[1,80,102,139],"study":[2,141],"of":[3,5,14,59,87,105,146,192,214],"polymorphisms":[4,37],"genes":[6,42,217],"differentially":[7,224],"expressed":[8,225],"may":[9],"lead":[10],"to":[11,40,73,129,237],"the":[12,51,174,215,239],"identification":[13],"putative":[15],"causal":[16],"genetic":[17,103],"variants":[18],"in":[19,77,97,117,132,142,168,188,226,247],"multifactorial":[20],"diseases":[21],"such":[22],"as":[23],"rheumatoid":[24],"arthritis":[25],"(RA).":[26],"Based":[27],"on":[28],"preceding":[29],"transcriptomic":[30],"results,":[31],"we":[32],"genotyped":[33],"10":[34],"single":[35],"nucleotide":[36],"(SNPs)":[38],"belonging":[39],"six":[41],"(S100A8,":[43],"RNASE2,":[44],"PGLYRP1,":[45],"RUNX3,":[46],"IL2RB,":[47],"and":[48,66,85,94,100,211],"LY96)":[49],"showing":[50],"highest":[52],"fold":[53],"change":[54],"(>":[55],"1.9)":[56],"when":[57],"level":[58],"expression":[60,84,126,222],"was":[61,89,127,166,185,223],"compared":[62],"between":[63,82,209],"RA":[64,98,109,134,156,171,210,227],"patients":[65,99,135,172,228],"controls.":[67,101],"These":[68],"SNPs":[69,88,107],"were":[70,110],"then":[71,111],"analysed":[72,112],"evaluate":[74],"their":[75],"role":[76],"RA.":[78,248],"METHOD:":[79],"relationship":[81],"gene":[83,125,221,246],"genotypes":[86,131],"first":[90],"investigated":[91],"by":[92],"Kruskal-Wallis":[93],"Mann-Whitney":[95],"tests":[96,116,203],"association":[104,115,140,154,165,184,202,208],"these":[106],"with":[108,155],"using":[113],"family-based":[114],"trio":[118,149,195],"families.":[119],"RESULTS:":[120],"We":[121],"found":[122,187],"that":[123],"RNASE2":[124,220],"related":[128],"rs2013109":[130],"14":[133],"(p":[136,161,179,197],"=":[137,162,180,198],"0.030).":[138],"a":[143,152,189,230],"discovery":[144],"sample":[145,191],"200":[147],"French":[148],"families":[150,196],"revealed":[151],"significant":[153],"for":[157,243],"one":[158],"SNP,":[159],"PGLYRP1-rs2041992":[160],"0.019);":[163],"this":[164,183,244],"stronger":[167],"trios":[169],"where":[170],"carried":[173],"HLA-DRB1":[175],"shared":[176],"epitope":[177],"(SE)":[178],"0.003).":[181],"However,":[182,219],"not":[186,205],"replication":[190],"240":[193],"European":[194],"0.6).":[199],"CONCLUSIONS:":[200],"Family-based":[201],"did":[204],"reveal":[206],"an":[207],"any":[212],"SNP":[213],"candidate":[216,245],"tested.":[218],"considering":[229],"sequence":[231],"polymorphism.":[232],"This":[233],"result":[234],"led":[235],"us":[236],"highlight":[238],"potential":[240],"disease-specific":[241],"regulation":[242]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}