{"id":"https://openalex.org/W2072089869","doi":"https://doi.org/10.1002/micr.20065","title":"Technique for retransplanting heterotopic heart grafts in mice","display_name":"Technique for retransplanting heterotopic heart grafts in mice","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2072089869","doi":"https://doi.org/10.1002/micr.20065","mag":"2072089869","pmid":"https://pubmed.ncbi.nlm.nih.gov/15378574"},"language":"en","primary_location":{"id":"doi:10.1002/micr.20065","doi":"https://doi.org/10.1002/micr.20065","is_oa":false,"landing_page_url":"https://doi.org/10.1002/micr.20065","pdf_url":null,"source":{"id":"https://openalex.org/S51047553","display_name":"Microsurgery","issn_l":"0738-1085","issn":["0738-1085","1098-2752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsurgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100350196","display_name":"Qi Li","orcid":"https://orcid.org/0000-0002-1921-4979","observed_orcids":["https://orcid.org/0000-0002-1921-4979"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qi Li","raw_affiliation_strings":["Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 065420, USA. qi.li@yale.edu","Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 065420, USA. qi.li@yale.edu","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004434222","display_name":"Yinong Wang","orcid":"https://orcid.org/0000-0003-0954-3493","observed_orcids":["https://orcid.org/0000-0003-0954-3493"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yinong Wang","raw_affiliation_strings":["Department of Surgery, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028806508","display_name":"Tai Yi","orcid":"https://orcid.org/0000-0003-0464-1043","observed_orcids":["https://orcid.org/0000-0003-0464-1043"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tai Yi","raw_affiliation_strings":["Department of Surgery, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113487552","display_name":"Geetha Chalasani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Geetha Chalasani","raw_affiliation_strings":["Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024123604","display_name":"Zhenhua Dai","orcid":"https://orcid.org/0000-0002-6236-8105","observed_orcids":["https://orcid.org/0000-0002-6236-8105"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhenhua Dai","raw_affiliation_strings":["Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055641686","display_name":"Marc I. Lorber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marc I. Lorber","raw_affiliation_strings":["Department of Surgery, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036202065","display_name":"George Tellides","orcid":"https://orcid.org/0000-0001-7042-8190","observed_orcids":["https://orcid.org/0000-0001-7042-8190"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George Tellides","raw_affiliation_strings":["Department of Surgery, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073466889","display_name":"Fadi G. Lakkis","orcid":"https://orcid.org/0000-0001-9937-2637","observed_orcids":["https://orcid.org/0000-0001-9937-2637"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fadi G. Lakkis","raw_affiliation_strings":["Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Nephrology and Section of Immunobiology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100350196"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":0.3158,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.67983528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"24","issue":"6","first_page":"465","last_page":"467"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12654","display_name":"Xenotransplantation and immune response","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-retransplantation","display_name":"heart retransplantation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/heart-transplantation","display_name":"heart transplantation","score":0.4410000145435333},{"id":"https://openalex.org/keywords/graft-rejection","display_name":"graft rejection","score":0.6129999756813049},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.9440000057220459},{"id":"https://openalex.org/keywords/microsurgical-anastomosis","display_name":"microsurgical anastomosis","score":0.8040000200271606},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.4519999921321869},{"id":"https://openalex.org/keywords/immunodeficient-mice","display_name":"immunodeficient mice","score":0.6290000081062317}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9582111835479736},{"id":"https://openalex.org/C2910216633","wikidata":"https://www.wikidata.org/wiki/Q745438","display_name":"Inferior vena cava","level":2,"score":0.7123658657073975},{"id":"https://openalex.org/C2781437307","wikidata":"https://www.wikidata.org/wiki/Q977628","display_name":"Microsurgery","level":2,"score":0.6868598461151123},{"id":"https://openalex.org/C8443397","wikidata":"https://www.wikidata.org/wiki/Q15177","display_name":"Anastomosis","level":2,"score":0.6679859757423401},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.6657230257987976},{"id":"https://openalex.org/C2780520971","wikidata":"https://www.wikidata.org/wiki/Q2264329","display_name":"Abdominal aorta","level":3,"score":0.646789014339447},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.6369040012359619},{"id":"https://openalex.org/C2779983558","wikidata":"https://www.wikidata.org/wiki/Q9597","display_name":"Abdomen","level":2,"score":0.5206845998764038},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4438198208808899}],"mesh":[{"descriptor_ui":"D000714","descriptor_name":"Anastomosis, Surgical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000938","descriptor_name":"Antigen-Presenting Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001012","descriptor_name":"Aorta, Abdominal","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D001012","descriptor_name":"Aorta, Abdominal","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008866","descriptor_name":"Microsurgery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013156","descriptor_name":"Splenectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014185","descriptor_name":"Transplantation, Isogeneic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014682","descriptor_name":"Vena Cava, Inferior","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D014682","descriptor_name":"Vena Cava, Inferior","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":false},{"descriptor_ui":"D015428","descriptor_name":"Myocardial Reperfusion Injury","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D016027","descriptor_name":"Heart Transplantation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016027","descriptor_name":"Heart Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016042","descriptor_name":"Transplantation, Heterotopic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/micr.20065","doi":"https://doi.org/10.1002/micr.20065","is_oa":false,"landing_page_url":"https://doi.org/10.1002/micr.20065","pdf_url":null,"source":{"id":"https://openalex.org/S51047553","display_name":"Microsurgery","issn_l":"0738-1085","issn":["0738-1085","1098-2752"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsurgery","raw_type":"journal-article"},{"id":"pmid:15378574","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15378574","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsurgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1692468525","display_name":"Chronic DTH and IFN-gamma in Human Graft Arteriosclerosis","funder_award_id":"P01HL070295","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3736158124","display_name":null,"funder_award_id":"P01 HL70295-01","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4398458399","display_name":null,"funder_award_id":"AI44644","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4486109017","display_name":null,"funder_award_id":"AI49466","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5387821321","display_name":"T Cell Memory in Organ Transplantation","funder_award_id":"R01AI049466","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W213324783","https://openalex.org/W650129009","https://openalex.org/W2067846827","https://openalex.org/W2092843904","https://openalex.org/W2126659232"],"related_works":["https://openalex.org/W1971310788","https://openalex.org/W4200416510","https://openalex.org/W2049486130","https://openalex.org/W2377244081","https://openalex.org/W2351101444","https://openalex.org/W2392337568","https://openalex.org/W4403500713","https://openalex.org/W2080558718","https://openalex.org/W2358107315","https://openalex.org/W7097583344"],"abstract_inverted_index":{"Removal":[0],"of":[1,24,37,61,85,92,147],"a":[2,13,34,46,62,86],"transplanted":[3],"organ":[4],"from":[5],"its":[6],"original":[7],"recipient":[8],"and":[9,57,98,109,140],"retransplanting":[10],"it":[11],"into":[12,82],"new":[14],"host":[15],"is":[16,51,80],"an":[17],"important":[18],"method":[19,128],"to":[20,53,103],"study":[21],"the":[22,25,28,41,54,77,83,93,104,145],"role":[23],"graft":[26,50,79],"in":[27,40],"rejection":[29],"process.":[30],"Here":[31],"we":[32],"describe":[33],"novel":[35],"technique":[36],"heart":[38,49],"retransplantation":[39],"mouse.":[42],"In":[43],"this":[44,124],"technique,":[45],"primarily":[47],"vascularized":[48],"anastomosed":[52],"abdominal":[55,107],"aorta":[56,108],"inferior":[58,99,110],"vena":[59,100,111],"cava":[60],"syngeneic":[63],"or":[64,73],"immunodeficient":[65],"allogeneic":[66],"mouse,":[67],"using":[68,123],"standard":[69],"techniques.":[70],"Either":[71],"10":[72],"70":[74],"days":[75],"later,":[76],"same":[78],"retransplanted":[81],"abdomen":[84],"second":[87,105],"mouse":[88],"by":[89,122],"end-to-side":[90],"anastomosis":[91],"donor":[94,141],"(first":[95],"recipient)":[96],"aortic":[97],"cava's":[101],"cuffs":[102],"recipient's":[106],"cava,":[112],"respectively.":[113],"A":[114],"greater":[115],"than":[116],"90%":[117],"success":[118],"rate":[119],"was":[120],"achieved":[121],"microsurgical":[125],"technique.":[126],"This":[127],"should":[129],"be":[130],"useful":[131],"for":[132],"studying":[133],"intragraft":[134],"factors,":[135],"such":[136],"as":[137],"ischemia-reperfusion":[138],"injury":[139],"antigen-presenting":[142],"cells,":[143],"on":[144],"outcomes":[146],"transplantations.":[148]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}