{"id":"https://openalex.org/W2072056933","doi":"https://doi.org/10.5551/jat.13.31","title":"Coronary Artery Calcification Revisited","display_name":"Coronary Artery Calcification Revisited","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2072056933","doi":"https://doi.org/10.5551/jat.13.31","mag":"2072056933","pmid":"https://pubmed.ncbi.nlm.nih.gov/16505589"},"language":"en","primary_location":{"id":"doi:10.5551/jat.13.31","doi":"https://doi.org/10.5551/jat.13.31","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.13.31","pdf_url":"https://www.jstage.jst.go.jp/article/jat/13/1/13_1_31/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jstage.jst.go.jp/article/jat/13/1/13_1_31/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081095133","display_name":"Shoichi Ehara","orcid":"https://orcid.org/0000-0001-7445-5516","observed_orcids":["https://orcid.org/0000-0001-7445-5516"]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shoichi Ehara","raw_affiliation_strings":["Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan. ehara@med.osaka-cu.ac.jp","Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine, Osaka, Japan. ehara@med.osaka-cu.ac.jp","institution_ids":["https://openalex.org/I317356780"]},{"raw_affiliation_string":"Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083198484","display_name":"\u82b3\u6a39 \u5c0f\u6797","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshiki Kobayashi","raw_affiliation_strings":["Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110822041","display_name":"Minoru Yoshiyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Minoru Yoshiyama","raw_affiliation_strings":["Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine and Cardiology, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074241677","display_name":"Makiko Ueda","orcid":"https://orcid.org/0000-0001-6725-3801","observed_orcids":["https://orcid.org/0000-0001-6725-3801"]},"institutions":[{"id":"https://openalex.org/I317356780","display_name":"Osaka City University","ror":"https://ror.org/02skfsw40","country_code":"JP","type":"education","lineage":["https://openalex.org/I317356780","https://openalex.org/I4387152983"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makiko Ueda","raw_affiliation_strings":["Department of Pathology, Osaka City University, Graduate School of Medicine, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Osaka City University, Graduate School of Medicine, Osaka, Japan","institution_ids":["https://openalex.org/I317356780"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026433163","display_name":"Junichi Yoshikawa","orcid":"https://orcid.org/0000-0003-1490-1558","observed_orcids":["https://orcid.org/0000-0003-1490-1558"]},"institutions":[{"id":"https://openalex.org/I4210112882","display_name":"Osaka Ekisaikai Hospital","ror":"https://ror.org/02ay4fy51","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210112882"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junichi Yoshikawa","raw_affiliation_strings":["Osaka Ekisaikai Hospital, Osaka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Ekisaikai Hospital, Osaka, Japan","institution_ids":["https://openalex.org/I4210112882"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.785,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.61815336,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"13","issue":"1","first_page":"31","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.8349999785423279,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.8349999785423279,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.15320000052452087,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coronary-artery-calcification","display_name":"coronary artery calcification","score":0.996999979019165},{"id":"https://openalex.org/keywords/vulnerable-plaque","display_name":"vulnerable plaque","score":0.6869999766349792},{"id":"https://openalex.org/keywords/unstable-plaque","display_name":"plaque vulnerability","score":0.7900000214576721},{"id":"https://openalex.org/keywords/intravascular-ultrasound","display_name":"intravascular ultrasound","score":0.8510000109672546},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.9049999713897705},{"id":"https://openalex.org/keywords/stable-angina","display_name":"stable angina","score":0.9919999837875366},{"id":"https://openalex.org/keywords/positive-remodeling","display_name":"positive remodeling","score":0.8209999799728394},{"id":"https://openalex.org/keywords/fibrofatty-plaque","display_name":"fibrofatty plaque","score":0.859000027179718},{"id":"https://openalex.org/keywords/lipid-core","display_name":"lipid core","score":0.8880000114440918},{"id":"https://openalex.org/keywords/spotty-calcification","display_name":"spotty calcification","score":0.8659999966621399}],"concepts":[{"id":"https://openalex.org/C2776931568","wikidata":"https://www.wikidata.org/wiki/Q1671577","display_name":"Intravascular ultrasound","level":2,"score":0.8368370532989502},{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.8366008996963501},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8085982799530029},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6663608551025391},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6184672117233276},{"id":"https://openalex.org/C2778742706","wikidata":"https://www.wikidata.org/wiki/Q18361829","display_name":"Coronary arteries","level":3,"score":0.5883051156997681},{"id":"https://openalex.org/C2993958921","wikidata":"https://www.wikidata.org/wiki/Q180762","display_name":"Stable angina","level":3,"score":0.5496177077293396},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.5172051191329956},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.46897539496421814},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.4370253384113312},{"id":"https://openalex.org/C2777785093","wikidata":"https://www.wikidata.org/wiki/Q2032041","display_name":"Unstable angina","level":3,"score":0.42455899715423584}],"mesh":[{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019160","descriptor_name":"Endosonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.5551/jat.13.31","doi":"https://doi.org/10.5551/jat.13.31","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.13.31","pdf_url":"https://www.jstage.jst.go.jp/article/jat/13/1/13_1_31/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},{"id":"pmid:16505589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16505589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of atherosclerosis and thrombosis","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5551/jat.13.31","doi":"https://doi.org/10.5551/jat.13.31","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.13.31","pdf_url":"https://www.jstage.jst.go.jp/article/jat/13/1/13_1_31/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2072056933.pdf","grobid_xml":"https://content.openalex.org/works/W2072056933.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1979939384","https://openalex.org/W1981395503","https://openalex.org/W1988116406","https://openalex.org/W2005345642","https://openalex.org/W2005447894","https://openalex.org/W2011935133","https://openalex.org/W2042227739","https://openalex.org/W2047173144","https://openalex.org/W2047334981","https://openalex.org/W2056893401","https://openalex.org/W2061886045","https://openalex.org/W2066387850","https://openalex.org/W2067307516","https://openalex.org/W2069297972","https://openalex.org/W2073273481","https://openalex.org/W2073751205","https://openalex.org/W2074610325","https://openalex.org/W2083806996","https://openalex.org/W2085343007","https://openalex.org/W2087255170","https://openalex.org/W2088956783","https://openalex.org/W2093664978","https://openalex.org/W2112278367","https://openalex.org/W2115268091","https://openalex.org/W2123974465","https://openalex.org/W2127256519","https://openalex.org/W2128715037","https://openalex.org/W2140385719","https://openalex.org/W2144093179","https://openalex.org/W2147339811","https://openalex.org/W2156244896","https://openalex.org/W2160656586","https://openalex.org/W2317358310","https://openalex.org/W2409722202"],"related_works":["https://openalex.org/W2036119994","https://openalex.org/W2140385719","https://openalex.org/W2617605845","https://openalex.org/W2465754850","https://openalex.org/W1840020261","https://openalex.org/W2405457340","https://openalex.org/W2036293365","https://openalex.org/W1490118385","https://openalex.org/W3172572741","https://openalex.org/W2074610325"],"abstract_inverted_index":{"Calcification":[0],"is":[1,11],"a":[2,15,28,59,90,99],"common":[3],"finding":[4],"in":[5,47,66,83],"human":[6],"coronary":[7,84],"arteries.":[8],"However,":[9],"there":[10],"conflicting":[12],"evidence":[13],"for":[14],"link":[16],"between":[17],"calcification":[18,33,73],"and":[19,34,62,94],"plaque":[20,61],"instability.":[21],"Current":[22],"intravascular":[23],"ultrasound":[24],"(IVUS)":[25],"technology":[26],"allows":[27,77],"definitive":[29],"detection":[30,79],"of":[31,36,80,102],"the":[32,37,78],"measurement":[35],"vessel":[38],"wall.":[39],"Using":[40],"preinterventional":[41],"IVUS":[42,76],"images,":[43],"we":[44],"clarified":[45],"that":[46],"patients":[48,67],"with":[49,58,68],"acute":[50],"myocardial":[51],"infarction,":[52],"small":[53],"\"spotty\"":[54],"calcifications":[55],"prevailed,":[56],"associated":[57],"fibrofatty":[60],"positive":[63,95],"remodeling.":[64],"Conversely,":[65],"stable":[69],"angina":[70],"pectoris,":[71],"extensive":[72],"was":[74],"frequent.":[75],"vulnerable":[81],"plaques":[82],"arteries,":[85],"by":[86],"identifying":[87],"not":[88],"only":[89],"large":[91],"lipid":[92],"core":[93],"remodeling,":[96],"but":[97],"also":[98],"spotty":[100],"pattern":[101],"calcification.":[103]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}