{"id":"https://openalex.org/W2071955506","doi":"https://doi.org/10.1161/01.atv.12.6.682","title":"A DNA polymorphism for LCAT is associated with altered LCAT activity and high density lipoprotein size distributions in baboons.","display_name":"A DNA polymorphism for LCAT is associated with altered LCAT activity and high density lipoprotein size distributions in baboons.","publication_year":1992,"publication_date":"1992-06-01","ids":{"openalex":"https://openalex.org/W2071955506","doi":"https://doi.org/10.1161/01.atv.12.6.682","mag":"2071955506","pmid":"https://pubmed.ncbi.nlm.nih.gov/1350465"},"language":"en","primary_location":{"id":"doi:10.1161/01.atv.12.6.682","doi":"https://doi.org/10.1161/01.atv.12.6.682","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.12.6.682","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.12.6.682","source":{"id":"https://openalex.org/S4210240347","display_name":"Arteriosclerosis and Thrombosis A Journal of Vascular Biology","issn_l":"1049-8834","issn":["1049-8834","2330-9199"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis and Thrombosis: A Journal of Vascular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.12.6.682","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082680532","display_name":"David L. Rainwater","orcid":"https://orcid.org/0000-0002-3668-4331","observed_orcids":["https://orcid.org/0000-0002-3668-4331"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D L Rainwater","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004538115","display_name":"John Blangero","orcid":"https://orcid.org/0000-0001-6250-5723","observed_orcids":["https://orcid.org/0000-0001-6250-5723"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Blangero","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054280155","display_name":"James E. Hixson","orcid":"https://orcid.org/0000-0002-0849-9315","observed_orcids":["https://orcid.org/0000-0002-0849-9315"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J E Hixson","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S Birnbaum","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S Birnbaum","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112498361","display_name":"Glen E. Mott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G E Mott","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016947225","display_name":"John L. VandeBerg","orcid":"https://orcid.org/0000-0002-7087-979X","observed_orcids":["https://orcid.org/0000-0002-7087-979X"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J L VandeBerg","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147","institution_ids":["https://openalex.org/I1289525096"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1289525096"],"apc_list":null,"apc_paid":null,"fwci":3.8283,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.93467664,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"12","issue":"6","first_page":"682","last_page":"690"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.9345999956130981,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.9345999956130981,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.02410000003874302,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.017400000244379044,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lcat","display_name":"lecithin:cholesterol acyltransferase","score":0.9909999966621399},{"id":"https://openalex.org/keywords/intron-5","display_name":"intron 5","score":0.75},{"id":"https://openalex.org/keywords/baboons","display_name":"baboons","score":0.7319999933242798},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.656000018119812},{"id":"https://openalex.org/keywords/apolipoprotein-a-i","display_name":"apolipoprotein A-I","score":0.9340000152587891},{"id":"https://openalex.org/keywords/hdl3","display_name":"HDL3","score":0.8130000233650208},{"id":"https://openalex.org/keywords/cholesterol-metabolism","display_name":"cholesterol metabolism","score":0.6290000081062317},{"id":"https://openalex.org/keywords/atherogenic-diet","display_name":"atherogenic diet","score":0.8149999976158142},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.6290000081062317},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.5879999995231628}],"concepts":[{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.7026033997535706},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.6693506836891174},{"id":"https://openalex.org/C964641","wikidata":"https://www.wikidata.org/wiki/Q424716","display_name":"Lecithin\u2014cholesterol acyltransferase","level":4,"score":0.6438857913017273},{"id":"https://openalex.org/C2779594886","wikidata":"https://www.wikidata.org/wiki/Q159429","display_name":"Baboon","level":2,"score":0.6413824558258057},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6345280408859253},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6345114707946777},{"id":"https://openalex.org/C37002583","wikidata":"https://www.wikidata.org/wiki/Q418755","display_name":"Sterol O-acyltransferase","level":4,"score":0.6186949610710144},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5906533002853394},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5725680589675903},{"id":"https://openalex.org/C153471976","wikidata":"https://www.wikidata.org/wiki/Q2873354","display_name":"Heterozygote advantage","level":4,"score":0.5664717555046082},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.5422992706298828},{"id":"https://openalex.org/C2779564620","wikidata":"https://www.wikidata.org/wiki/Q241595","display_name":"Lecithin","level":2,"score":0.5118967294692993},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.509596586227417},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.4775984287261963},{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.4553641676902771},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.4485076665878296},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.41659241914749146},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2777370810508728},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23474586009979248},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17440325021743774},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10048374533653259},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007862","descriptor_name":"Phosphatidylcholine-Sterol O-Acyltransferase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007862","descriptor_name":"Phosphatidylcholine-Sterol O-Acyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008075","descriptor_name":"Lipoproteins, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010215","descriptor_name":"Papio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012150","descriptor_name":"Polymorphism, Restriction Fragment Length","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015252","descriptor_name":"Deoxyribonucleases, Type II Site-Specific","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016632","descriptor_name":"Apolipoprotein A-I","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1161/01.atv.12.6.682","doi":"https://doi.org/10.1161/01.atv.12.6.682","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.12.6.682","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.12.6.682","source":{"id":"https://openalex.org/S4210240347","display_name":"Arteriosclerosis and Thrombosis A Journal of Vascular Biology","issn_l":"1049-8834","issn":["1049-8834","2330-9199"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis and Thrombosis: A Journal of Vascular Biology","raw_type":"journal-article"},{"id":"pmid:1350465","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1350465","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis and thrombosis : a journal of vascular biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.830.1463","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.830.1463","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://atvb.ahajournals.org/content/12/6/682.full.pdf","raw_type":"text"},{"id":"mag:3148048020","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/atv91.12.6.1350465?cited-by=yesr12%2F6%2F682","pdf_url":null,"source":{"id":"https://openalex.org/S4210240347","display_name":"Arteriosclerosis and Thrombosis A Journal of Vascular Biology","issn_l":"1049-8834","issn":["1049-8834","2330-9199"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Arteriosclerosis and Thrombosis: A Journal of Vascular Biology","raw_type":null}],"best_oa_location":{"id":"doi:10.1161/01.atv.12.6.682","doi":"https://doi.org/10.1161/01.atv.12.6.682","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.12.6.682","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.12.6.682","source":{"id":"https://openalex.org/S4210240347","display_name":"Arteriosclerosis and Thrombosis A Journal of Vascular Biology","issn_l":"1049-8834","issn":["1049-8834","2330-9199"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis and Thrombosis: A Journal of Vascular Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2006841341","display_name":"NONHUMAN PRIMATE MODELS OF ATHEROSCLEROSIS/HYPERTENSION","funder_award_id":"n01hv053030-028","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2873144787","display_name":null,"funder_award_id":"HL-28972","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G518769146","display_name":null,"funder_award_id":"HV-53030","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6843954451","display_name":"Diet and Genotype in Primate Atherosclerosis","funder_award_id":"P01HL028972","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2071955506.pdf","grobid_xml":"https://content.openalex.org/works/W2071955506.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W143383438","https://openalex.org/W1492212334","https://openalex.org/W1513994146","https://openalex.org/W1552121147","https://openalex.org/W1709756153","https://openalex.org/W1893651774","https://openalex.org/W1932595303","https://openalex.org/W1946263363","https://openalex.org/W1968551431","https://openalex.org/W1971728585","https://openalex.org/W1973150839","https://openalex.org/W1988582229","https://openalex.org/W1990986783","https://openalex.org/W1997583050","https://openalex.org/W2008844806","https://openalex.org/W2019150102","https://openalex.org/W2020376434","https://openalex.org/W2022756457","https://openalex.org/W2033168374","https://openalex.org/W2033518322","https://openalex.org/W2035559804","https://openalex.org/W2042385191","https://openalex.org/W2050324148","https://openalex.org/W2050717506","https://openalex.org/W2056862882","https://openalex.org/W2068797485","https://openalex.org/W2072310823","https://openalex.org/W2080744397","https://openalex.org/W2082220604","https://openalex.org/W2082807908","https://openalex.org/W2083997718","https://openalex.org/W2108333058","https://openalex.org/W2111774300","https://openalex.org/W2122224620","https://openalex.org/W2157971481","https://openalex.org/W2166325326","https://openalex.org/W2181839796","https://openalex.org/W2182332740","https://openalex.org/W2184332109","https://openalex.org/W2226655261","https://openalex.org/W2276495252","https://openalex.org/W2309042381","https://openalex.org/W2336419393","https://openalex.org/W2342991650","https://openalex.org/W2407845087","https://openalex.org/W2409578693","https://openalex.org/W2411406722","https://openalex.org/W2419198402","https://openalex.org/W4299542564","https://openalex.org/W4299870384","https://openalex.org/W4323517781","https://openalex.org/W4372144402"],"related_works":["https://openalex.org/W2034608884","https://openalex.org/W2116997743","https://openalex.org/W1831040923","https://openalex.org/W2074193765","https://openalex.org/W2103739208","https://openalex.org/W1994463222","https://openalex.org/W2082220604","https://openalex.org/W2046844111","https://openalex.org/W2127432329","https://openalex.org/W2049746692"],"abstract_inverted_index":{"A":[0],"polymorphic":[1],"Pvu":[2],"II":[3],"site":[4],"was":[5],"mapped":[6],"to":[7],"intron":[8],"5":[9],"of":[10,23,50,70,85,109,134,146,152,172,183,206],"LCAT,":[11],"the":[12,41,51,189,199,221,225],"gene":[13],"encoding":[14],"baboon":[15,105],"lecithin:":[16],"cholesterol":[17,64,75,86,115,136,154,173,184,210],"acyltransferase":[18],"(LCAT).":[19],"In":[20,140],"a":[21,110,203],"study":[22],"83":[24],"baboons,":[25],"heterozygous":[26],"baboons":[27,38,128],"(Pv1/Pv2)":[28],"had":[29,129,169],"significantly":[30,130],"higher":[31],"LCAT":[32,46,55,147,200,226,234],"enzyme":[33,56,235],"activity":[34,236],"levels":[35,133],"than":[36,137],"did":[37,138,162],"homozygous":[39],"for":[40,60,103],"more":[42],"common":[43],"allele":[44],"(Pv1/Pv1).":[45],"genotype":[47,148],"explained":[48,202],"6%":[49],"total":[52,135,207],"variation":[53,208],"in":[54,114,177,188,209,233,240],"activity.":[57],"To":[58],"test":[59],"allelic":[61],"effects":[62,145],"on":[63,123,149,158,217],"metabolism,":[65],"we":[66,142],"compared":[67,83],"serum":[68,132],"concentrations":[69],"high":[71],"density":[72],"lipoprotein":[73],"(HDL)":[74],"and":[76,87,97,116,118,155,174,180,185,212,237],"apolipoprotein":[77],"A-I":[78,89,157,176,187,214],"(apo":[79],"A-I).":[80],"We":[81],"also":[82],"distributions":[84,151,216],"apo":[88,156,175,186,213],"among":[90],"three":[91],"HDL":[92,153,191,241],"size":[93,150,192],"classes":[94,193],"(HDL1,":[95],"HDL2,":[96],"HDL3).":[98],"All":[99],"measurements":[100],"were":[101],"obtained":[102],"each":[104],"after":[106,120],"long-term":[107],"feeding":[108],"basal":[111],"diet":[112],"low":[113],"fat":[117],"again":[119],"7":[121],"weeks":[122],"an":[124],"atherogenic":[125],"diet.":[126],"Heterozygous":[127],"lower":[131,181],"homozygotes.":[139,197],"addition,":[141],"detected":[143],"significant":[144,204,231],"both":[159,218],"diets":[160],"but":[161],"not":[163],"detect":[164],"any":[165],"genotype-by-diet":[166],"interaction.":[167],"Heterozygotes":[168],"increased":[170],"amounts":[171,182],"HDL3":[178],"particles":[179],"larger":[190],"by":[194],"comparison":[195],"with":[196,230,238],"Overall,":[198],"polymorphism":[201,227],"proportion":[205],"(4-10%)":[211],"(13%)":[215],"diets.":[219],"Thus,":[220],"results":[222],"indicate":[223],"that":[224],"is":[228],"associated":[229],"differences":[232],"alterations":[239],"compositions.":[242]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}