{"id":"https://openalex.org/W2071950078","doi":"https://doi.org/10.1517/14712598.2014.858116","title":"Effectiveness and safety of erythropoiesis-stimulating agent use in the perioperative period","display_name":"Effectiveness and safety of erythropoiesis-stimulating agent use in the perioperative period","publication_year":2013,"publication_date":"2013-11-13","ids":{"openalex":"https://openalex.org/W2071950078","doi":"https://doi.org/10.1517/14712598.2014.858116","mag":"2071950078","pmid":"https://pubmed.ncbi.nlm.nih.gov/24219367"},"language":"en","primary_location":{"id":"doi:10.1517/14712598.2014.858116","doi":"https://doi.org/10.1517/14712598.2014.858116","is_oa":false,"landing_page_url":"https://doi.org/10.1517/14712598.2014.858116","pdf_url":null,"source":{"id":"https://openalex.org/S57380513","display_name":"Expert Opinion on Biological Therapy","issn_l":"1471-2598","issn":["1471-2598","1744-7682"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Biological Therapy","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002449256","display_name":"Diane HD Tran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800810863","display_name":"Queen Mary Hospital","ror":"https://ror.org/02xkx3e48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I2800810863"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Diane HD Tran","raw_affiliation_strings":["University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk","institution_ids":["https://openalex.org/I2800810863","https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103413266","display_name":"Gordon TC Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800810863","display_name":"Queen Mary Hospital","ror":"https://ror.org/02xkx3e48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I2800810863"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Gordon TC Wong","raw_affiliation_strings":["University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk","institution_ids":["https://openalex.org/I2800810863","https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083138570","display_name":"Yee Eot Chee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800810863","display_name":"Queen Mary Hospital","ror":"https://ror.org/02xkx3e48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I2800810863"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Yee Eot Chee","raw_affiliation_strings":["University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk","institution_ids":["https://openalex.org/I2800810863","https://openalex.org/I889458895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075622190","display_name":"Michael G. Irwin","orcid":"https://orcid.org/0000-0001-5801-274X","observed_orcids":["https://orcid.org/0000-0001-5801-274X"]},"institutions":[{"id":"https://openalex.org/I2800810863","display_name":"Queen Mary Hospital","ror":"https://ror.org/02xkx3e48","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I2800810863"]},{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Michael G Irwin","raw_affiliation_strings":["University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Hong Kong, Queen Mary Hospital, Department of Anaesthesiology, 102 Pokfulam Road, HK, Hong Kong gordon@hku.hk","institution_ids":["https://openalex.org/I2800810863","https://openalex.org/I889458895"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4913,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.38753894,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"14","issue":"1","first_page":"51","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9125999808311462,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.9125999808311462,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.08569999784231186,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythropoiesis-stimulating-agents","display_name":"erythropoiesis-stimulating agents","score":0.9990000128746033},{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":0.9760000109672546},{"id":"https://openalex.org/keywords/perioperative-anemia","display_name":"perioperative anemia","score":0.7630000114440918},{"id":"https://openalex.org/keywords/allogeneic-blood-transfusion","display_name":"allogeneic blood transfusion","score":0.9020000100135803},{"id":"https://openalex.org/keywords/transfusion-reduction","display_name":"transfusion reduction","score":0.48899999260902405},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.6209999918937683},{"id":"https://openalex.org/keywords/adverse-cardiovascular-events","display_name":"cardiovascular adverse events","score":0.6200000047683716},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.6990000009536743},{"id":"https://openalex.org/keywords/thromboembolism","display_name":"thromboembolism","score":0.8970000147819519},{"id":"https://openalex.org/keywords/intraoperative-blood-loss","display_name":"intraoperative blood loss","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9084178805351257},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.810254693031311},{"id":"https://openalex.org/C2777288759","wikidata":"https://www.wikidata.org/wiki/Q4164182","display_name":"Dosing","level":2,"score":0.8042107820510864},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.7507651448249817},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.7137434482574463},{"id":"https://openalex.org/C2776164570","wikidata":"https://www.wikidata.org/wiki/Q5383794","display_name":"Epoetin alfa","level":3,"score":0.6462792754173279},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.5417736768722534},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4745006263256073},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.44643014669418335},{"id":"https://openalex.org/C2778534260","wikidata":"https://www.wikidata.org/wiki/Q218706","display_name":"Erythropoietin","level":2,"score":0.4181348383426666},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2837693691253662},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21998581290245056},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001803","descriptor_name":"Blood Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004920","descriptor_name":"Erythropoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004921","descriptor_name":"Erythropoietin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006397","descriptor_name":"Hematinics","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D006397","descriptor_name":"Hematinics","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016063","descriptor_name":"Blood Loss, Surgical","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019106","descriptor_name":"Postoperative Hemorrhage","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019106","descriptor_name":"Postoperative Hemorrhage","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D019990","descriptor_name":"Perioperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1517/14712598.2014.858116","doi":"https://doi.org/10.1517/14712598.2014.858116","is_oa":false,"landing_page_url":"https://doi.org/10.1517/14712598.2014.858116","pdf_url":null,"source":{"id":"https://openalex.org/S57380513","display_name":"Expert Opinion on Biological Therapy","issn_l":"1471-2598","issn":["1471-2598","1744-7682"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Opinion on Biological Therapy","raw_type":"journal-article"},{"id":"pmid:24219367","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24219367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert opinion on biological therapy","raw_type":"Journal Article"},{"id":"pmh:oai:hub.hku.hk:10722/193162","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10722/193162","pdf_url":null,"source":{"id":"https://openalex.org/S4377196271","display_name":"The HKU Scholars Hub (University of Hong Kong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I889458895","host_organization_name":"University of Hong Kong","host_organization_lineage":["https://openalex.org/I889458895"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W26122530","https://openalex.org/W122174934","https://openalex.org/W170849090","https://openalex.org/W1608757922","https://openalex.org/W1752254530","https://openalex.org/W1967512627","https://openalex.org/W1976714933","https://openalex.org/W1977820130","https://openalex.org/W1996619807","https://openalex.org/W1998943227","https://openalex.org/W2001796138","https://openalex.org/W2009255958","https://openalex.org/W2011196639","https://openalex.org/W2023245037","https://openalex.org/W2028722252","https://openalex.org/W2037347063","https://openalex.org/W2038879581","https://openalex.org/W2039412193","https://openalex.org/W2040029744","https://openalex.org/W2047514408","https://openalex.org/W2048749101","https://openalex.org/W2056058233","https://openalex.org/W2057170780","https://openalex.org/W2059364207","https://openalex.org/W2061473093","https://openalex.org/W2072223552","https://openalex.org/W2082526002","https://openalex.org/W2088071732","https://openalex.org/W2093362111","https://openalex.org/W2093705233","https://openalex.org/W2100222319","https://openalex.org/W2109328187","https://openalex.org/W2109827973","https://openalex.org/W2115598659","https://openalex.org/W2116841847","https://openalex.org/W2119138117","https://openalex.org/W2123200029","https://openalex.org/W2123639625","https://openalex.org/W2136886013","https://openalex.org/W2140043294","https://openalex.org/W2143449839","https://openalex.org/W2149512015","https://openalex.org/W2155208959","https://openalex.org/W2156338292","https://openalex.org/W2157630652","https://openalex.org/W2159738034","https://openalex.org/W2170110528","https://openalex.org/W2331665138","https://openalex.org/W3149132779","https://openalex.org/W4242329867","https://openalex.org/W4252687781"],"related_works":["https://openalex.org/W4387708783","https://openalex.org/W2069287065","https://openalex.org/W2050401388","https://openalex.org/W3096637305","https://openalex.org/W4401778182","https://openalex.org/W2150135873","https://openalex.org/W2932715234","https://openalex.org/W1988146807","https://openalex.org/W2911116908","https://openalex.org/W2472036269"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Erythropoiesis-stimulating":[1],"agents":[2],"(ESAs)":[3],"are":[4,15],"widely":[5],"used":[6,18,186],"in":[7,29,136,177,182,201],"treating":[8],"anemia":[9],"associated":[10,44,58],"with":[11,33,45,59,139,184],"renal":[12,141],"failure.":[13],"They":[14],"also":[16],"now":[17],"perioperatively":[19],"to":[20,78,125,165,193,203],"reduce":[21,41,126],"the":[22,42,52,80,84,120,127,161,169,195,205],"use":[23,53,121],"of":[24,50,54,88,94,105,122,197],"allogeneic":[25],"blood":[26,36],"transfusions":[27],"(ABTs)":[28],"patients":[30,138],"undergoing":[31],"surgery":[32],"anticipated":[34],"high":[35],"loss.":[37],"Although":[38],"they":[39],"can":[40,157],"risks":[43],"ABT":[46],"and":[47,71,86,96,113,150,180,208],"improve":[48],"quality":[49],"life,":[51],"ESAs":[55,70,90,124],"is":[56,67],"still":[57],"adverse":[60,145,210],"effects.":[61],"AREAS":[62],"COVERED:":[63],"A":[64,92],"narrative":[65],"review":[66,74],"provided":[68],"on":[69],"a":[72,103],"systematic":[73],"has":[75,99],"been":[76,100,174],"conducted":[77],"examine":[79],"current":[81],"evidence":[82,118],"for":[83,129,187],"efficacy":[85],"safety":[87,112,135],"perioperative":[89,123,170],"use.":[91],"search":[93,106],"PubMed":[95],"Medline":[97],"databases":[98],"performed":[101],"using":[102],"combination":[104],"terms":[107],"including":[108,147],"erythropoietin,":[109],"perioperative,":[110],"surgical,":[111],"efficacy.":[114],"EXPERT":[115],"OPINION:":[116],"Current":[117],"supports":[119],"need":[128],"ABT.":[130],"However,":[131,153],"large":[132],"studies":[133],"assessing":[134],"anemic":[137],"chronic":[140,188],"disease":[142],"have":[143,173],"found":[144],"effects":[146,207],"cardiovascular,":[148],"stroke":[149],"thromboembolic":[151],"events.":[152,211],"whether":[154],"these":[155],"concerns":[156],"be":[158,166],"conferred":[159],"onto":[160],"surgical":[162],"population":[163],"remains":[164],"seen":[167],"as":[168],"dosing":[171,199],"strategies":[172,200],"more":[175],"variable":[176],"timing,":[178],"dose":[179],"duration":[181],"comparison":[183],"those":[185],"diseases.":[189],"Future":[190],"research":[191],"needs":[192],"address":[194],"questions":[196],"optimal":[198],"order":[202],"maximize":[204],"positive":[206],"minimize":[209]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}