{"id":"https://openalex.org/W2071944927","doi":"https://doi.org/10.1038/sj.onc.1205572","title":"MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site","display_name":"MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site","publication_year":2002,"publication_date":"2002-07-05","ids":{"openalex":"https://openalex.org/W2071944927","doi":"https://doi.org/10.1038/sj.onc.1205572","mag":"2071944927","pmid":"https://pubmed.ncbi.nlm.nih.gov/12096348"},"language":"en","primary_location":{"id":"doi:10.1038/sj.onc.1205572","doi":"https://doi.org/10.1038/sj.onc.1205572","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.onc.1205572","pdf_url":null,"source":{"id":"https://openalex.org/S128439998","display_name":"Oncogene","issn_l":"0950-9232","issn":["0950-9232","1476-5594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063783317","display_name":"Diana J. Slater","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diana J Slater","raw_affiliation_strings":["Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, PA 19104, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, PA 19104, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018366667","display_name":"Eva Hilgenfeld","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]},{"id":"https://openalex.org/I4210103666","display_name":"University Hospital M\u00fcnster","ror":"https://ror.org/01856cw59","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210103666"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Eva Hilgenfeld","raw_affiliation_strings":["Genetics Division, National Cancer Institute, Bethesda, 20892, Maryland, MD, USA","Hematology/Oncology, Medizinische Klinik und Poliklinik A, University of Muenster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Division, National Cancer Institute, Bethesda, 20892, Maryland, MD, USA","institution_ids":["https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Hematology/Oncology, Medizinische Klinik und Poliklinik A, University of Muenster, Germany","institution_ids":["https://openalex.org/I22465464","https://openalex.org/I4210103666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109345826","display_name":"Eric F. Rappaport","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric F Rappaport","raw_affiliation_strings":["Joseph Stokes Jr, Research Institute, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","Joseph Stokes, Jr Research Institute, Children's Hospital of Philadelphia, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joseph Stokes Jr, Research Institute, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","institution_ids":["https://openalex.org/I1335321130"]},{"raw_affiliation_string":"Joseph Stokes, Jr Research Institute, Children's Hospital of Philadelphia, Philadelphia, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033131710","display_name":"Narayan R. Shah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1293487830","display_name":"Geisinger Medical Center","ror":"https://ror.org/03j9npf54","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1293487830","https://openalex.org/I54713919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Narayan Shah","raw_affiliation_strings":["Division of Hematology/Oncology, Department of Pediatrics, Geisinger Medical Center, Danville, 17822, Pennsylvania, PA, USA","Division of Hematology/Oncology, Department of Pediatrics, Geisinger Medical Center, Danville, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, Department of Pediatrics, Geisinger Medical Center, Danville, 17822, Pennsylvania, PA, USA","institution_ids":["https://openalex.org/I1293487830"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Department of Pediatrics, Geisinger Medical Center, Danville, USA","institution_ids":["https://openalex.org/I1293487830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110011365","display_name":"Rita Meek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1326254912","display_name":"Alfred I. duPont Hospital for Children","ror":"https://ror.org/00jyx0v10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1326254912","https://openalex.org/I4210108049"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rita G Meek","raw_affiliation_strings":["Division of Hematology/Oncology, Department of Pediatrics, Alfred I Dupont Institute, Wilmington, 19899, Delaware, DE, USA","Division of Hematology/Oncology, Department of Pediatrics, Alfred I Dupont Institute, Wilmington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology/Oncology, Department of Pediatrics, Alfred I Dupont Institute, Wilmington, 19899, Delaware, DE, USA","institution_ids":["https://openalex.org/I1326254912"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Department of Pediatrics, Alfred I Dupont Institute, Wilmington, USA","institution_ids":["https://openalex.org/I1326254912"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wendy Reed Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wendy Reed Williams","raw_affiliation_strings":["Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","institution_ids":["https://openalex.org/I1335321130"]},{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006901304","display_name":"Brian D. Lovett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian D Lovett","raw_affiliation_strings":["Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, USA","Pennsylvania State University College of Medicine, Hershey, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","institution_ids":["https://openalex.org/I1335321130"]},{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, USA","institution_ids":["https://openalex.org/I1335321130"]},{"raw_affiliation_string":"Pennsylvania State University College of Medicine, Hershey, USA","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041320360","display_name":"Neil Osheroff","orcid":"https://orcid.org/0000-0002-2550-4884","observed_orcids":["https://orcid.org/0000-0002-2550-4884","https://orcid.org/0000-0003-0355-4773"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil Osheroff","raw_affiliation_strings":["Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, 37232, Tennessee, TN, USA","Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, 37232, Tennessee, TN, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029626784","display_name":"Reshma Saskia Autar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2802928900","display_name":"Amsterdam UMC Location University of Amsterdam","ror":"https://ror.org/03t4gr691","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2802928900","https://openalex.org/I4210151833"]},{"id":"https://openalex.org/I887064364","display_name":"University of Amsterdam","ror":"https://ror.org/04dkp9463","country_code":"NL","type":"education","lineage":["https://openalex.org/I887064364"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"Reshma S Autar","raw_affiliation_strings":["Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, USA","University of Amsterdam of the Medical Faculty of the Academic Medical Center of Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","institution_ids":["https://openalex.org/I1335321130"]},{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, USA","institution_ids":["https://openalex.org/I1335321130"]},{"raw_affiliation_string":"University of Amsterdam of the Medical Faculty of the Academic Medical Center of Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2802928900","https://openalex.org/I887064364"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031392514","display_name":"Thomas Ried","orcid":"https://orcid.org/0000-0002-0767-6009","observed_orcids":["https://orcid.org/0000-0002-0767-6009"]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Ried","raw_affiliation_strings":["Genetics Division, National Cancer Institute, Bethesda, 20892, Maryland, MD, USA","Genetics Division, National Cancer Institute, Bethesda, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Division, National Cancer Institute, Bethesda, 20892, Maryland, MD, USA","institution_ids":["https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Genetics Division, National Cancer Institute, Bethesda, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105981798","display_name":"Carolyn A. Felix","orcid":"https://orcid.org/0000-0002-4335-6993","observed_orcids":["https://orcid.org/0000-0002-4335-6993"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"funder","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Carolyn A Felix","raw_affiliation_strings":["Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, 19104, Pennsylvania, PA, USA","Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, USA","Division of Oncology, Children\u2019s Hospital of Philadelphia, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, 19104, Pennsylvania, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, 19104, Pennsylvania, PA, USA","institution_ids":["https://openalex.org/I1335321130"]},{"raw_affiliation_string":"Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Division of Oncology, Children\u2019s Hospital of Philadelphia, Philadelphia, USA","institution_ids":["https://openalex.org/I1335321130"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5105981798"],"corresponding_institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"],"apc_list":{"value":5990,"currency":"USD","value_usd":5990},"apc_paid":null,"fwci":3.837,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.93869882,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"21","issue":"30","first_page":"4706","last_page":"4714"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mll-translocation","display_name":"MLL translocation","score":0.7889999747276306},{"id":"https://openalex.org/keywords/acute-myelomonocytic-leukemia","display_name":"acute myelomonocytic leukemia","score":0.9200000166893005},{"id":"https://openalex.org/keywords/complex-chromosomal-rearrangements","display_name":"complex chromosomal rearrangements","score":0.6940000057220459},{"id":"https://openalex.org/keywords/msf","display_name":"MSF","score":0.9869999885559082},{"id":"https://openalex.org/keywords/leukemogenesis","display_name":"leukemogenesis","score":0.7350000143051147},{"id":"https://openalex.org/keywords/fusion-transcripts","display_name":"fusion transcripts","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C206936463","wikidata":"https://www.wikidata.org/wiki/Q634179","display_name":"Breakpoint","level":4,"score":0.8739504814147949},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8708195686340332},{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.7473679184913635},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.6657482385635376},{"id":"https://openalex.org/C53226629","wikidata":"https://www.wikidata.org/wiki/Q189967","display_name":"Karyotype","level":4,"score":0.6376301646232605},{"id":"https://openalex.org/C2778274637","wikidata":"https://www.wikidata.org/wiki/Q5510282","display_name":"Fusion transcript","level":4,"score":0.6270442008972168},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6148360967636108},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5423558354377747},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.5166807174682617},{"id":"https://openalex.org/C133307689","wikidata":"https://www.wikidata.org/wiki/Q48749","display_name":"Southern blot","level":3,"score":0.48582741618156433},{"id":"https://openalex.org/C2992511266","wikidata":"https://www.wikidata.org/wiki/Q1093098","display_name":"Gene rearrangement","level":3,"score":0.4492376148700714},{"id":"https://openalex.org/C17757408","wikidata":"https://www.wikidata.org/wiki/Q4135516","display_name":"genomic DNA","level":3,"score":0.41277700662612915},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31363940238952637},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.2963123321533203}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002880","descriptor_name":"Chromosomes, Human, Pair 11","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002893","descriptor_name":"Chromosomes, Human, Pair 3","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003598","descriptor_name":"Cytoskeletal Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004250","descriptor_name":"DNA Topoisomerases, Type II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007951","descriptor_name":"Leukemia, Myeloid","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011495","descriptor_name":"Histone-Lysine N-Methyltransferase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011519","descriptor_name":"Proto-Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014178","descriptor_name":"Translocation, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014960","descriptor_name":"X Chromosome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015479","descriptor_name":"Leukemia, Myelomonocytic, Acute","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019204","descriptor_name":"GTP-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019457","descriptor_name":"Chromosome Breakage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051788","descriptor_name":"Myeloid-Lymphoid Leukemia Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058112","descriptor_name":"Septins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/sj.onc.1205572","doi":"https://doi.org/10.1038/sj.onc.1205572","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.onc.1205572","pdf_url":null,"source":{"id":"https://openalex.org/S128439998","display_name":"Oncogene","issn_l":"0950-9232","issn":["0950-9232","1476-5594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"journal-article"},{"id":"pmid:12096348","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12096348","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/14","score":0.5699999928474426,"display_name":"Life below water"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[{"id":"https://openalex.org/G1338606963","display_name":"Molecular Genetic Changes in Leukemia in Infants","funder_award_id":"R01CA080175","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1412068617","display_name":null,"funder_award_id":"CA80175","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1593503869","display_name":null,"funder_award_id":"GM 33944","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2210873228","display_name":null,"funder_award_id":"CA77683","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G384624924","display_name":null,"funder_award_id":"CA85469","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6531455616","display_name":"Function and Biology of Eukaryotic DNA Topoisomerases","funder_award_id":"R01GM033944","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6551681428","display_name":"BIOMARKERS OF TREATMENT RELATED LEUKEMIA","funder_award_id":"R01CA085469","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7129243497","display_name":"ANTINEOPLASTIC v LEUKEMOGENIC EPIPODOPHYLLOTOXIN EFFECTS","funder_award_id":"R01CA077683","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320308295","display_name":"Leukemia and Lymphoma Society","ror":"https://ror.org/04m0xav37"},{"id":"https://openalex.org/F4320323556","display_name":"Deutsche Krebshilfe","ror":"https://ror.org/01wxdd722"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W4474461","https://openalex.org/W37845799","https://openalex.org/W72913968","https://openalex.org/W82240137","https://openalex.org/W123495240","https://openalex.org/W237111889","https://openalex.org/W279116378","https://openalex.org/W590848019","https://openalex.org/W1515498851","https://openalex.org/W1526487990","https://openalex.org/W1565552070","https://openalex.org/W1572512950","https://openalex.org/W1582596547","https://openalex.org/W1587615774","https://openalex.org/W1786259862","https://openalex.org/W1847176704","https://openalex.org/W1976631985","https://openalex.org/W1977546547","https://openalex.org/W1982640053","https://openalex.org/W1986658762","https://openalex.org/W1988582699","https://openalex.org/W1990863885","https://openalex.org/W1997394042","https://openalex.org/W1997397984","https://openalex.org/W1997670036","https://openalex.org/W2001886943","https://openalex.org/W2004373779","https://openalex.org/W2008601218","https://openalex.org/W2009685139","https://openalex.org/W2012220765","https://openalex.org/W2015410199","https://openalex.org/W2027003150","https://openalex.org/W2034682816","https://openalex.org/W2036296056","https://openalex.org/W2036839079","https://openalex.org/W2037479635","https://openalex.org/W2044820954","https://openalex.org/W2044884259","https://openalex.org/W2047519730","https://openalex.org/W2050778299","https://openalex.org/W2050800108","https://openalex.org/W2058873773","https://openalex.org/W2065130184","https://openalex.org/W2071916629","https://openalex.org/W2075368420","https://openalex.org/W2082866416","https://openalex.org/W2087283266","https://openalex.org/W2093846063","https://openalex.org/W2095184701","https://openalex.org/W2095405591","https://openalex.org/W2101085659","https://openalex.org/W2103646675","https://openalex.org/W2115540872","https://openalex.org/W2117646322","https://openalex.org/W2119749554","https://openalex.org/W2129995506","https://openalex.org/W2137114892","https://openalex.org/W2139860130","https://openalex.org/W2144551286","https://openalex.org/W2161679878","https://openalex.org/W2164304095","https://openalex.org/W2166907165","https://openalex.org/W2169704403","https://openalex.org/W2320868553","https://openalex.org/W2331191863","https://openalex.org/W2339359539","https://openalex.org/W2736870608","https://openalex.org/W4232374197","https://openalex.org/W4237833990"],"related_works":["https://openalex.org/W2168261943","https://openalex.org/W2084508429","https://openalex.org/W2139860130","https://openalex.org/W2112216325","https://openalex.org/W2145871939","https://openalex.org/W2170141201","https://openalex.org/W2144551286","https://openalex.org/W1986131842","https://openalex.org/W4232374197","https://openalex.org/W190101321"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}