{"id":"https://openalex.org/W2071908798","doi":"https://doi.org/10.1016/0168-3659(95)00183-2","title":"Poly(\u03b1-hydroxy acid) carrier for delivering recombinant human bone morphogenetic protein-2 for bone regeneration","display_name":"Poly(\u03b1-hydroxy acid) carrier for delivering recombinant human bone morphogenetic protein-2 for bone regeneration","publication_year":1996,"publication_date":"1996-05-01","ids":{"openalex":"https://openalex.org/W2071908798","doi":"https://doi.org/10.1016/0168-3659(95)00183-2","mag":"2071908798"},"language":"en","primary_location":{"id":"doi:10.1016/0168-3659(95)00183-2","doi":"https://doi.org/10.1016/0168-3659(95)00183-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0168-3659(95)00183-2","pdf_url":null,"source":{"id":"https://openalex.org/S161954266","display_name":"Journal of Controlled Release","issn_l":"0168-3659","issn":["0168-3659","1873-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Controlled Release","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111043831","display_name":"Jared Hollinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J. Hollinger","raw_affiliation_strings":["Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112442802","display_name":"Michael H. Mayer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Mayer","raw_affiliation_strings":["Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111495950","display_name":"Dave C. Buck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Buck","raw_affiliation_strings":["Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050538210","display_name":"H. Daniel Zegzula","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Zegzula","raw_affiliation_strings":["Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oregon Health Sciences University, 3181 SW Sam Jackson Park Rd L352A, Portland, OR 97201-3098, USA","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046555436","display_name":"Eyal S. Ron","orcid":"https://orcid.org/0000-0003-3433-4562","observed_orcids":["https://orcid.org/0000-0003-3433-4562"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Ron","raw_affiliation_strings":["GelMed, 213 Burlington Road, Bedford, MA 01730, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GelMed, 213 Burlington Road, Bedford, MA 01730, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Smith","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Smith","raw_affiliation_strings":["Genetics Institute, One Burtt Rd, Andover, MA 01810, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Institute, One Burtt Rd, Andover, MA 01810, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"L. Jin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Jin","raw_affiliation_strings":["Genetics Institute, One Burtt Rd, Andover, MA 01810, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Institute, One Burtt Rd, Andover, MA 01810, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088552955","display_name":"John M. Wozney","orcid":"https://orcid.org/0000-0001-5460-6815","observed_orcids":["https://orcid.org/0000-0001-5460-6815"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Wozney","raw_affiliation_strings":["Genetics Institute, One Burtt Rd, Andover, MA 01810, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Institute, One Burtt Rd, Andover, MA 01810, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111043831"],"corresponding_institution_ids":["https://openalex.org/I165690674"],"apc_list":{"value":4440,"currency":"USD","value_usd":4440},"apc_paid":null,"fwci":4.5567,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.94940927,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"39","issue":"2-3","first_page":"287","last_page":"304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhbmp-2","display_name":"rhBMP-2","score":0.949999988079071},{"id":"https://openalex.org/keywords/poly-lactic-co-glycolic-acid","display_name":"poly(lactic-co-glycolic acid)","score":0.902999997138977},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.7749999761581421},{"id":"https://openalex.org/keywords/bone-defects","display_name":"bone defects","score":0.7960000038146973},{"id":"https://openalex.org/keywords/allogeneic-bone","display_name":"allogeneic bone","score":0.718999981880188},{"id":"https://openalex.org/keywords/controlled-drug-delivery","display_name":"controlled drug delivery","score":0.6840000152587891}],"concepts":[{"id":"https://openalex.org/C2779079599","wikidata":"https://www.wikidata.org/wiki/Q3774464","display_name":"Iliac crest","level":2,"score":0.8376578092575073},{"id":"https://openalex.org/C31507581","wikidata":"https://www.wikidata.org/wiki/Q425383","display_name":"Bone morphogenetic protein","level":3,"score":0.717952311038971},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6121016144752502},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.5518056154251099},{"id":"https://openalex.org/C30352789","wikidata":"https://www.wikidata.org/wiki/Q14903153","display_name":"Bone morphogenetic protein 2","level":3,"score":0.5300951600074768},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.5163472890853882},{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.44433826208114624},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4362573027610779},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.16402456164360046},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16390076279640198},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11053311824798584},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10737401247024536},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.07382199168205261},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/0168-3659(95)00183-2","doi":"https://doi.org/10.1016/0168-3659(95)00183-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0168-3659(95)00183-2","pdf_url":null,"source":{"id":"https://openalex.org/S161954266","display_name":"Journal of Controlled Release","issn_l":"0168-3659","issn":["0168-3659","1873-4995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Controlled Release","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W54668368","https://openalex.org/W1496740624","https://openalex.org/W1502127219","https://openalex.org/W1517038772","https://openalex.org/W1549455124","https://openalex.org/W1655444266","https://openalex.org/W1755214722","https://openalex.org/W1853269734","https://openalex.org/W1902783929","https://openalex.org/W1968822620","https://openalex.org/W1975168711","https://openalex.org/W1975357704","https://openalex.org/W1975828859","https://openalex.org/W1976584345","https://openalex.org/W1986469118","https://openalex.org/W1987295787","https://openalex.org/W1991573324","https://openalex.org/W1998781840","https://openalex.org/W2004573486","https://openalex.org/W2012333093","https://openalex.org/W2012992333","https://openalex.org/W2013404858","https://openalex.org/W2029040734","https://openalex.org/W2029415593","https://openalex.org/W2037997875","https://openalex.org/W2040249570","https://openalex.org/W2043070543","https://openalex.org/W2045799047","https://openalex.org/W2047144232","https://openalex.org/W2059585969","https://openalex.org/W2059905814","https://openalex.org/W2070994703","https://openalex.org/W2073981823","https://openalex.org/W2084101932","https://openalex.org/W2089946224","https://openalex.org/W2091103523","https://openalex.org/W2092012724","https://openalex.org/W2093654042","https://openalex.org/W2095978877","https://openalex.org/W2100703201","https://openalex.org/W2107833077","https://openalex.org/W2113240961","https://openalex.org/W2117115638","https://openalex.org/W2127936916","https://openalex.org/W2128179614","https://openalex.org/W2131211068","https://openalex.org/W2142258375","https://openalex.org/W2144259467","https://openalex.org/W2168905766","https://openalex.org/W2208640131","https://openalex.org/W2227538606","https://openalex.org/W2233320357","https://openalex.org/W2255736307","https://openalex.org/W2289446650","https://openalex.org/W2313378491","https://openalex.org/W2340065664","https://openalex.org/W2434545165","https://openalex.org/W2438921174","https://openalex.org/W2767155929","https://openalex.org/W4229606223","https://openalex.org/W4231167940","https://openalex.org/W4239171241","https://openalex.org/W4255781844","https://openalex.org/W4293411852","https://openalex.org/W6611145640","https://openalex.org/W6696767174"],"related_works":["https://openalex.org/W2107833077","https://openalex.org/W2071846257","https://openalex.org/W2001527223","https://openalex.org/W2022409816","https://openalex.org/W2094111430","https://openalex.org/W2767661233","https://openalex.org/W3092930079","https://openalex.org/W2112650040","https://openalex.org/W2009230779","https://openalex.org/W1972875582"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}