{"id":"https://openalex.org/W2071753136","doi":"https://doi.org/10.1155/2000/919260","title":"Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins","display_name":"Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins","publication_year":2000,"publication_date":"2000-01-01","ids":{"openalex":"https://openalex.org/W2071753136","doi":"https://doi.org/10.1155/2000/919260","mag":"2071753136","pmid":"https://pubmed.ncbi.nlm.nih.gov/10900456","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2448332"},"language":"en","primary_location":{"id":"doi:10.1155/2000/919260","doi":"https://doi.org/10.1155/2000/919260","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2000/919260","pdf_url":"https://downloads.hindawi.com/journals/ijg/2000/919260.pdf","source":{"id":"https://openalex.org/S80252601","display_name":"Yeast","issn_l":"0749-503X","issn":["0749-503X","1097-0061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yeast","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/ijg/2000/919260.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065533632","display_name":"Micheline Fromont\u2010Racine","orcid":"https://orcid.org/0000-0001-9906-0334","observed_orcids":["https://orcid.org/0000-0001-9906-0334"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Micheline Fromont-Racine","raw_affiliation_strings":["G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, Paris Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, Paris Cedex 15, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026782155","display_name":"Andrew E. Mayes","orcid":"https://orcid.org/0000-0003-4060-0660","observed_orcids":["https://orcid.org/0000-0003-4060-0660"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew E. Mayes","raw_affiliation_strings":["Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004325428","display_name":"Adeline Simon","orcid":"https://orcid.org/0000-0002-0020-6442","observed_orcids":["https://orcid.org/0000-0002-0020-6442"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Adeline Brunet-Simon","raw_affiliation_strings":["G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]},{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008102729","display_name":"Jean\u2010Christophe Rain","orcid":"https://orcid.org/0000-0001-8110-0641","observed_orcids":["https://orcid.org/0000-0001-8110-0641"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Christophe Rain","raw_affiliation_strings":["G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]},{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045201259","display_name":"Alan Colley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alan Colley","raw_affiliation_strings":["Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023871211","display_name":"Ian Dix","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ian Dix","raw_affiliation_strings":["Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088118853","display_name":"Laurence Decourty","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laurence Decourty","raw_affiliation_strings":["G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]},{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nicolas Joly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nicolas Joly","raw_affiliation_strings":["Service d'Informatique Scientifique, Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","Service d'Informatique Scientifique, Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service d'Informatique Scientifique, Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Service d'Informatique Scientifique, Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France","institution_ids":["https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082986730","display_name":"Florence Ricard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Florence Ricard","raw_affiliation_strings":["G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]},{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073859869","display_name":"Jean D. Beggs","orcid":"https://orcid.org/0000-0002-8179-6519","observed_orcids":["https://orcid.org/0000-0002-8179-6519"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jean D. Beggs","raw_affiliation_strings":["Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings, Mayfield Road, Edinburgh EH9 3JR","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Institute of Cell and Molecular Biology, University of Edinburgh, King's Buildings Mayfield Road, Edinburgh, EH9 3JR, UK","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064028987","display_name":"Pierre Legrain","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Pierre Legrain","raw_affiliation_strings":["G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300) Institut Pasteur, 25-28 rue du Dr Roux, Paris Cedex 15 75724","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]},{"raw_affiliation_string":"G\u00e9n\u00e9tique des Interactions Macromol\u00e9culaires, CNRS (URA 1300), Institut Pasteur, 25\u201328 rue du Dr Roux, 75724\u2009Paris Cedex 15, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5064028987"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I157536573"],"apc_list":{"value":3980,"currency":"USD","value_usd":3980},"apc_paid":{"value":3980,"currency":"USD","value_usd":3980},"fwci":7.1664,"has_fulltext":true,"cited_by_count":209,"citation_normalized_percentile":{"value":0.98266181,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"1","issue":"2","first_page":"95","last_page":"110"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lsm-proteins","display_name":"Lsm proteins","score":0.9710000157356262},{"id":"https://openalex.org/keywords/sm-like-proteins","display_name":"Sm-like proteins","score":0.878000020980835},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.8690000176429749},{"id":"https://openalex.org/keywords/spliceosome","display_name":"spliceosome","score":0.7179999947547913},{"id":"https://openalex.org/keywords/u4-u6-snrnp","display_name":"U4/U6 snRNP","score":0.7329999804496765},{"id":"https://openalex.org/keywords/u6-snrna","display_name":"U6 snRNA","score":0.9020000100135803},{"id":"https://openalex.org/keywords/mrna-turnover","display_name":"mRNA turnover","score":0.8080000281333923},{"id":"https://openalex.org/keywords/dcp1","display_name":"DCP1","score":0.6740000247955322},{"id":"https://openalex.org/keywords/dcp2","display_name":"Dcp2","score":0.9919999837875366},{"id":"https://openalex.org/keywords/xrn1","display_name":"Xrn1","score":0.9850000143051147},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.8759999871253967},{"id":"https://openalex.org/keywords/rna-metabolism","display_name":"RNA metabolism","score":0.6129999756813049}],"concepts":[{"id":"https://openalex.org/C68483431","wikidata":"https://www.wikidata.org/wiki/Q2076770","display_name":"snRNP","level":5,"score":0.6162642240524292},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5955782532691956},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.5360982418060303},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.4178861379623413},{"id":"https://openalex.org/C144292202","wikidata":"https://www.wikidata.org/wiki/Q898273","display_name":"Protein domain","level":3,"score":0.41785621643066406},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41483891010284424},{"id":"https://openalex.org/C40000846","wikidata":"https://www.wikidata.org/wiki/Q915868","display_name":"Spliceosome","level":5,"score":0.4130040407180786},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4110007584095001},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.3787999153137207},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3126886487007141},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.25920072197914124},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2577667236328125}],"mesh":[{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012326","descriptor_name":"RNA Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012331","descriptor_name":"RNA, Fungal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016681","descriptor_name":"Genome, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017411","descriptor_name":"Ribonucleoproteins, Small Nuclear","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017411","descriptor_name":"Ribonucleoproteins, Small Nuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D020798","descriptor_name":"Two-Hybrid System Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1155/2000/919260","doi":"https://doi.org/10.1155/2000/919260","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2000/919260","pdf_url":"https://downloads.hindawi.com/journals/ijg/2000/919260.pdf","source":{"id":"https://openalex.org/S80252601","display_name":"Yeast","issn_l":"0749-503X","issn":["0749-503X","1097-0061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yeast","raw_type":"journal-article"},{"id":"doi:10.1002/1097-0061(20000630)17:2<95::aid-yea16>3.0.co;2-h","doi":"https://doi.org/10.1002/1097-0061(20000630)17:2<95::aid-yea16>3.0.co;2-h","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0061(20000630)17:2<95::aid-yea16>3.0.co;2-h","pdf_url":null,"source":{"id":"https://openalex.org/S80252601","display_name":"Yeast","issn_l":"0749-503X","issn":["0749-503X","1097-0061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yeast","raw_type":"journal-article"},{"id":"pmid:10900456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10900456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yeast (Chichester, England)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2448332","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2448332/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yeast","raw_type":"Text"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/77336324-7d66-4b73-b5a3-dd501e5961cf","doi":null,"is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/77336324-7d66-4b73-b5a3-dd501e5961cf","pdf_url":"https://www.research.ed.ac.uk/files/10341583/Genome_Wide_Protein_Interaction_Screens_Reveal_Functional_Networks_Involving_Sm_Like_Proteins.pdf","source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Fromont-Racine, M, Mayes, A E, Brunet-Simon, A, Rain, J C, Colley, A, Dix, I, Decourty, L, Joly, N, Ricard, F, Beggs, J D & Legrain, P 2000, 'Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins', Yeast, vol. 17, no. 2, pp. 95-110. https://doi.org/10.1002/1097-0061(20000630)17:2<95::AID-YEA16>3.0.CO;2-H","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:pasteur-03439480v1","doi":null,"is_oa":false,"landing_page_url":"https://pasteur.hal.science/pasteur-03439480","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Yeast, 2000, 17 (2), pp.95-110. &#x27E8;10.1002/1097-0061(20000630)17:23.0.CO;2-H&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1155/2000/919260","doi":"https://doi.org/10.1155/2000/919260","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2000/919260","pdf_url":"https://downloads.hindawi.com/journals/ijg/2000/919260.pdf","source":{"id":"https://openalex.org/S80252601","display_name":"Yeast","issn_l":"0749-503X","issn":["0749-503X","1097-0061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yeast","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1274625865","display_name":null,"funder_award_id":"047685","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4091174763","display_name":null,"funder_award_id":"047685","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2071753136.pdf","grobid_xml":"https://content.openalex.org/works/W2071753136.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W48446126","https://openalex.org/W1485023011","https://openalex.org/W1575542444","https://openalex.org/W1644692915","https://openalex.org/W1657208855","https://openalex.org/W1833943928","https://openalex.org/W1834476919","https://openalex.org/W1881929849","https://openalex.org/W1905489680","https://openalex.org/W1942379865","https://openalex.org/W1964987091","https://openalex.org/W1968453920","https://openalex.org/W1983509070","https://openalex.org/W1988498926","https://openalex.org/W1990214042","https://openalex.org/W1991017037","https://openalex.org/W1997279341","https://openalex.org/W2006062026","https://openalex.org/W2022862659","https://openalex.org/W2035792284","https://openalex.org/W2041703851","https://openalex.org/W2053177462","https://openalex.org/W2065304353","https://openalex.org/W2066107954","https://openalex.org/W2066696278","https://openalex.org/W2068778722","https://openalex.org/W2071112476","https://openalex.org/W2073688200","https://openalex.org/W2079818352","https://openalex.org/W2080115238","https://openalex.org/W2088973552","https://openalex.org/W2095676095","https://openalex.org/W2097436619","https://openalex.org/W2098357851","https://openalex.org/W2100057937","https://openalex.org/W2104496647","https://openalex.org/W2116841494","https://openalex.org/W2118485393","https://openalex.org/W2118985834","https://openalex.org/W2121770428","https://openalex.org/W2124049693","https://openalex.org/W2133815301","https://openalex.org/W2134201576","https://openalex.org/W2142985191","https://openalex.org/W2144011606","https://openalex.org/W2146364074","https://openalex.org/W2151844976","https://openalex.org/W2152758802","https://openalex.org/W2158098213","https://openalex.org/W2165064583","https://openalex.org/W2166558964","https://openalex.org/W2169436908","https://openalex.org/W2252877470","https://openalex.org/W2266395920","https://openalex.org/W2314225431","https://openalex.org/W4245646325","https://openalex.org/W4388367253","https://openalex.org/W7093874238","https://openalex.org/W7096858812"],"related_works":["https://openalex.org/W1997279341","https://openalex.org/W2143138678","https://openalex.org/W1968160161","https://openalex.org/W2106543077","https://openalex.org/W2124049693","https://openalex.org/W2462862137","https://openalex.org/W2129752042","https://openalex.org/W7095929394","https://openalex.org/W7097807961","https://openalex.org/W1979566118"],"abstract_inverted_index":{"A":[0,24],"set":[1],"of":[2,11,26,30,37,55,100,148],"seven":[3],"structurally":[4,44],"related":[5],"Sm":[6,113,121],"proteins":[7,46,63,84,93,150,161],"forms":[8],"the":[9,12,16,27,53,61,69,82,98,111,120,145],"core":[10],"snRNP":[13],"particles":[14],"containing":[15],"spliceosomal":[17,152],"U1,":[18],"U2,":[19],"U4":[20],"and":[21,64,75,137,143,154,171,206],"U5":[22],"snRNAs.":[23],"search":[25],"genomic":[28,77],"sequence":[29],"Saccharomyces":[31],"cerevisiae":[32],"has":[33],"identified":[34],"a":[35,101,219],"number":[36],"open":[38],"reading":[39],"frames":[40],"that":[41,96,115,184,196],"potentially":[42],"encode":[43],"similar":[45],"termed":[47],"Lsm":[48,62,83,92,102,107,149,177],"(Like":[49],"Sm)":[50],"proteins.":[51,122],"With":[52],"aim":[54],"analysing":[56],"all":[57],"possible":[58],"interactions":[59,89,108,118,129,159,205],"between":[60,119],"any":[65],"protein":[66],"encoded":[67],"in":[68,133,163,179,187],"yeast":[70],"genome,":[71],"we":[72],"performed":[73,217],"exhaustive":[74],"iterative":[76],"two-hybrid":[78,197],"screens,":[79],"starting":[80],"with":[81,130,135,140,144,151,160],"as":[85,167],"baits.":[86],"Indeed,":[87],"extensive":[88],"amongst":[90],"eight":[91],"were":[94],"found":[95],"suggest":[97,208],"existence":[99],"complex":[103],"or":[104],"complexes.":[105],"These":[106,191],"apparently":[109],"involve":[110],"conserved":[112],"domain":[114],"also":[116,125],"mediates":[117],"The":[123],"screens":[124,198],"reveal":[126],"functionally":[127,200],"significant":[128],"splicing":[131],"factors,":[132],"particular":[134],"Prp4":[136],"Prp24,":[138],"compatible":[139],"genetic":[141],"studies":[142],"reported":[146],"association":[147],"U6":[153],"U4/U6":[155],"particles.":[156],"In":[157],"addition,":[158],"involved":[162],"mRNA":[164],"turnover,":[165],"such":[166],"Mrt1,":[168],"Dcp1,":[169],"Dcp2":[170],"Xrn1,":[172],"point":[173],"to":[174],"roles":[175],"for":[176,210],"complexes":[178],"distinct":[180],"RNA":[181],"metabolic":[182],"processes,":[183],"are":[185,216],"confirmed":[186],"independent":[188],"functional":[189],"studies.":[190],"results":[192],"provide":[193],"compelling":[194],"evidence":[195],"yield":[199],"meaningful":[201],"information":[202],"about":[203],"protein-protein":[204],"can":[207],"functions":[209],"uncharacterized":[211],"proteins,":[212],"especially":[213],"when":[214],"they":[215],"on":[218],"genome-wide":[220],"scale.":[221]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}